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Volumn 59, Issue 1, 2017, Pages R1-R10

Role of soluble and membrane-bound dipeptidyl peptidase-4 in diabetic nephropathy

Author keywords

Diabetic nephropathy; DPP 4; DPP 4 inhibitors; GLP 1 and SDF 1a

Indexed keywords

ALOGLIPTIN; ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GEMIGLIPTIN; GLUCAGON LIKE PEPTIDE 1; LINAGLIPTIN; LIRAGLUTIDE; METFORMIN; PLACEBO; SAXAGLIPTIN; SITAGLIPTIN; STREPTOZOCIN; STROMAL CELL DERIVED FACTOR 1ALPHA; SULFONYLUREA; VILDAGLIPTIN; ANTIDIABETIC AGENT; CXCL12 PROTEIN, HUMAN; DPP4 PROTEIN, HUMAN; PROTECTIVE AGENT; STROMAL CELL DERIVED FACTOR 1;

EID: 85024907511     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-17-0005     Document Type: Review
Times cited : (49)

References (60)
  • 2
    • 84885662277 scopus 로고    scopus 로고
    • Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension
    • discussion 2299
    • Chaykovska L, Alter ML, von Websky K, Hohmann M, Tsuprykov O, Reichetzeder C, Kutil B, Kraft R, Klein T & Hocher B 2013 Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension. Journal of Hypertension 31 2290–2298; discussion 2299. (doi:10.1097/HJH.0b013e3283649b4d)
    • (2013) Journal of Hypertension , vol.31 , pp. 2290-2298
    • Chaykovska, L.1    Alter, M.L.2    Von Websky, K.3    Hohmann, M.4    Tsuprykov, O.5    Reichetzeder, C.6    Kutil, B.7    Kraft, R.8    Klein, T.9    Hocher, B.10
  • 6
    • 84896883898 scopus 로고    scopus 로고
    • DPP-4 inhibition with alogliptin on top of angiotensin II type 1 receptor blockade ameliorates albuminuria via up-regulation of SDF-1alpha in type 2 diabetic patients with incipient nephropathy
    • Fujita H, Taniai H, Murayama H, Ohshiro H, Hayashi H, Sato S, Kikuchi N, Komatsu T, Komatsu K, Narita T, et al. 2014b DPP-4 inhibition with alogliptin on top of angiotensin II type 1 receptor blockade ameliorates albuminuria via up-regulation of SDF-1alpha in type 2 diabetic patients with incipient nephropathy. Endocrine Journal 61 159–166. (doi:10.1507/endocrj.EJ13-0305)
    • (2014) Endocrine Journal , vol.61 , pp. 159-166
    • Fujita, H.1    Taniai, H.2    Murayama, H.3    Ohshiro, H.4    Hayashi, H.5    Sato, S.6    Kikuchi, N.7    Komatsu, T.8    Komatsu, K.9    Narita, T.10
  • 7
    • 84990960882 scopus 로고    scopus 로고
    • Urinary albumin excretion with sitagliptin compared to sulfonylurea as add on to metformin in type 2 diabetes patients with albuminuria: A real-world evidence study
    • Goldshtein I, Karasik A, Melzer-Cohen C, Engel SS, Yu S, Sharon O, Brodovicz K, Gadir N, Katzeff HL, Radican L, et al. 2016 Urinary albumin excretion with sitagliptin compared to sulfonylurea as add on to metformin in type 2 diabetes patients with albuminuria: a real-world evidence study. Journal of Diabetic Complications 30 1354–1359. (doi:10.1016/j.jdiacomp.2016.05.012)
    • (2016) Journal of Diabetic Complications , vol.30 , pp. 1354-1359
    • Goldshtein, I.1    Karasik, A.2    Melzer-Cohen, C.3    Engel, S.S.4    Yu, S.5    Sharon, O.6    Brodovicz, K.7    Gadir, N.8    Katzeff, H.L.9    Radican, L.10
  • 8
    • 84890476805 scopus 로고    scopus 로고
    • Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction
    • Groop PH, Cooper ME, Perkovic V, Emser A, Woerle HJ & von Eynatten M 2013 Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction. Diabetes Care 36 3460–3468. (doi:10.2337/dc13-0323)
    • (2013) Diabetes Care , vol.36 , pp. 3460-3468
    • Groop, P.H.1    Cooper, M.E.2    Perkovic, V.3    Emser, A.4    Woerle, H.J.5    Von Eynatten, M.6
  • 9
    • 84945315616 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibition with linagliptin and effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: Rationale and design of the MARLINA-T2D trial
    • Groop PH, Cooper ME, Perkovic V, Sharma K, Schernthaner G, Haneda M, Hocher B, Gordat M, Cescutti J, Woerle HJ, et al. 2015 Dipeptidyl peptidase-4 inhibition with linagliptin and effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: Rationale and design of the MARLINA-T2D trial. Diabetes and Vascular Disease Research 12 455–462. (doi:10.1177/1479164115579002)
    • (2015) Diabetes and Vascular Disease Research , vol.12 , pp. 455-462
    • Groop, P.H.1    Cooper, M.E.2    Perkovic, V.3    Sharma, K.4    Schernthaner, G.5    Haneda, M.6    Hocher, B.7    Gordat, M.8    Cescutti, J.9    Woerle, H.J.10
  • 12
    • 79251604529 scopus 로고    scopus 로고
    • Sitagliptin reduces albuminuria in patients with type 2 diabetes
    • Hattori S 2011 Sitagliptin reduces albuminuria in patients with type 2 diabetes. Endocrine Journal 58 69–73. (doi:10.1507/endocrj.K10E-382)
    • (2011) Endocrine Journal , vol.58 , pp. 69-73
    • Hattori, S.1
  • 13
    • 84866732695 scopus 로고    scopus 로고
    • GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases
    • Hendarto H, Inoguchi T, Maeda Y, Ikeda N, Zheng J, Takei R, Yokomizo H, Hirata E, Sonoda N & Takayanagi R 2012 GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases. Metabolism 61 1422–1434. (doi:10.1016/j. metabol.2012.03.002)
    • (2012) Metabolism , vol.61 , pp. 1422-1434
    • Hendarto, H.1    Inoguchi, T.2    Maeda, Y.3    Ikeda, N.4    Zheng, J.5    Takei, R.6    Yokomizo, H.7    Hirata, E.8    Sonoda, N.9    Takayanagi, R.10
  • 15
    • 0013986243 scopus 로고
    • A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide
    • Hopsu-Havu VK & Glenner GG 1966 A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide. Histochemie 7 197–201. (doi:10.1007/BF00577838)
    • (1966) Histochemie , vol.7 , pp. 197-201
    • Hopsu-Havu, V.K.1    Glenner, G.G.2
  • 16
    • 84885000482 scopus 로고    scopus 로고
    • The glucagon-like peptide-1 receptor agonist, liraglutide, attenuates the progression of overt diabetic nephropathy in type 2 diabetic patients
    • Imamura S, Hirai K & Hirai A 2013 The glucagon-like peptide-1 receptor agonist, liraglutide, attenuates the progression of overt diabetic nephropathy in type 2 diabetic patients. Tohoku Journal of Experimental Medicine 231 57–61. (doi:10.1620/tjem.231.57)
    • (2013) Tohoku Journal of Experimental Medicine , vol.231 , pp. 57-61
    • Imamura, S.1    Hirai, K.2    Hirai, A.3
  • 17
    • 84979884860 scopus 로고    scopus 로고
    • Cardiac and renovascular complications in type 2 diabetes – is there hope?
    • Ingelfinger JR & Rosen CJ 2016 Cardiac and renovascular complications in type 2 diabetes – is there hope? New England Journal of Medicine 375 380–382. (doi:10.1056/NEJMe1607413)
    • (2016) New England Journal of Medicine , vol.375 , pp. 380-382
    • Ingelfinger, J.R.1    Rosen, C.J.2
  • 18
    • 84865447930 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV regulates proliferation of preglomerular vascular smooth muscle and mesangial cells
    • Jackson EK, Kochanek SJ & Gillespie DG 2012 Dipeptidyl peptidase IV regulates proliferation of preglomerular vascular smooth muscle and mesangial cells. Hypertension 60 757–764. (doi:10.1161/HYPERTENSIONAHA.112.196501)
    • (2012) Hypertension , vol.60 , pp. 757-764
    • Jackson, E.K.1    Kochanek, S.J.2    Gillespie, D.G.3
  • 19
    • 84929310684 scopus 로고    scopus 로고
    • Gemigliptin improves renal function and attenuates podocyte injury in mice with diabetic nephropathy
    • Jung E, Kim J, Ho Kim S, Kim S & Cho MH 2015 Gemigliptin improves renal function and attenuates podocyte injury in mice with diabetic nephropathy. European Journal of Pharmacology 761 116–124. (doi:10.1016/j.ejphar.2015.04.055)
    • (2015) European Journal of Pharmacology , vol.761 , pp. 116-124
    • Jung, E.1    Kim, J.2    Ho Kim, S.3    Kim, S.4    Cho, M.H.5
  • 20
    • 84901309585 scopus 로고    scopus 로고
    • Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen
    • Kanasaki K, Shi S, Kanasaki M, He J, Nagai T, Nakamura Y, Ishigaki Y, Kitada M, Srivastava SP & Koya D 2014 Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen. Diabetes 63 2120–2131. (doi:10.2337/db13-1029)
    • (2014) Diabetes , vol.63 , pp. 2120-2131
    • Kanasaki, K.1    Shi, S.2    Kanasaki, M.3    He, J.4    Nagai, T.5    Nakamura, Y.6    Ishigaki, Y.7    Kitada, M.8    Srivastava, S.P.9    Koya, D.10
  • 21
    • 0026703489 scopus 로고
    • Ultrastructural localization of dipeptidylpeptidase IV in the glomerulum of the rat kidney
    • Kettmann U, Humbel B & Holzhausen HJ 1992 Ultrastructural localization of dipeptidylpeptidase IV in the glomerulum of the rat kidney. Acta Histochemica 92 225–227. (doi:10.1016/S0065-1281(11)80085-1)
    • (1992) Acta Histochemica , vol.92 , pp. 225-227
    • Kettmann, U.1    Humbel, B.2    Holzhausen, H.J.3
  • 22
    • 79953826349 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
    • Kodera R, Shikata K, Kataoka HU, Takatsuka T, Miyamoto S, Sasaki M, Kajitani N, Nishishita S, Sarai K, Hirota D, et al. 2011 Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes. Diabetologia 54 965–978. (doi:10.1007/s00125-010-2028-x)
    • (2011) Diabetologia , vol.54 , pp. 965-978
    • Kodera, R.1    Shikata, K.2    Kataoka, H.U.3    Takatsuka, T.4    Miyamoto, S.5    Sasaki, M.6    Kajitani, N.7    Nishishita, S.8    Sarai, K.9    Hirota, D.10
  • 24
    • 84865227510 scopus 로고    scopus 로고
    • Inhibition of the expression of TGF-beta1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist
    • Li W, Cui M, Wei Y, Kong X, Tang L & Xu D 2012 Inhibition of the expression of TGF-beta1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist. Cellular Physiology and Biochemistry 30 749–757. (doi:10.1159/000341454)
    • (2012) Cellular Physiology and Biochemistry , vol.30 , pp. 749-757
    • Li, W.1    Cui, M.2    Wei, Y.3    Kong, X.4    Tang, L.5    Xu, D.6
  • 25
    • 84942798720 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury
    • Lim SW, Jin L, Piao SG, Chung BH & Yang CW 2015 Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury. Laboratory Investigation 95 1174–1185. (doi:10.1038/labinvest.2015.93)
    • (2015) Laboratory Investigation , vol.95 , pp. 1174-1185
    • Lim, S.W.1    Jin, L.2    Piao, S.G.3    Chung, B.H.4    Yang, C.W.5
  • 28
    • 84929074723 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 deficiency protects against experimental diabetic nephropathy partly by blocking the advanced glycation end products-receptor axis
    • Matsui T, Nakashima S, Nishino Y, Ojima A, Nakamura N, Arima K, Fukami K, Okuda S & Yamagishi S 2015 Dipeptidyl peptidase-4 deficiency protects against experimental diabetic nephropathy partly by blocking the advanced glycation end products-receptor axis. Laboratory Investigation 95 525–533. (doi:10.1038/labinvest.2015.35)
    • (2015) Laboratory Investigation , vol.95 , pp. 525-533
    • Matsui, T.1    Nakashima, S.2    Nishino, Y.3    Ojima, A.4    Nakamura, N.5    Arima, K.6    Fukami, K.7    Okuda, S.8    Yamagishi, S.9
  • 32
    • 54249132506 scopus 로고    scopus 로고
    • Diagnostic value of the aminopeptidase N,N-acetyl-beta-D-glucosaminidase and dipeptidylpeptidase IV in evaluating tubular dysfunction in patients with glomerulopathies
    • Mitic B, Lazarevic G, Vlahovic P, Rajic M & Stefanovic V 2008 Diagnostic value of the aminopeptidase N,N-acetyl-beta-D-glucosaminidase and dipeptidylpeptidase IV in evaluating tubular dysfunction in patients with glomerulopathies. Renal Failure 30 896–903. (doi:10.1080/08860220802359048)
    • (2008) Renal Failure , vol.30 , pp. 896-903
    • Mitic, B.1    Lazarevic, G.2    Vlahovic, P.3    Rajic, M.4    Stefanovic, V.5
  • 33
    • 84961226958 scopus 로고    scopus 로고
    • The dose-dependent organ-specific effects of a dipeptidyl peptidase-4 inhibitor on cardiovascular complications in a model of type 2 diabetes
    • Moon JY, Woo JS, Seo JW, Lee A, Kim DJ, Kim YG, Kim SY, Lee KH, Lim SJ, Cheng XW, et al. 2016 The dose-dependent organ-specific effects of a dipeptidyl peptidase-4 inhibitor on cardiovascular complications in a model of type 2 diabetes. PLoS ONE 11 e0150745. (doi:10.1371/journal.pone.0150745)
    • (2016) Plos ONE , vol.11
    • Moon, J.Y.1    Woo, J.S.2    Seo, J.W.3    Lee, A.4    Kim, D.J.5    Kim, Y.G.6    Kim, S.Y.7    Lee, K.H.8    Lim, S.J.9    Cheng, X.W.10
  • 34
    • 84920095184 scopus 로고    scopus 로고
    • Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors
    • Mulvihill EE & Drucker DJ 2014 Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors. Endocrine Reviews 35 992–1019. (doi:10.1210/er.2014-1035)
    • (2014) Endocrine Reviews , vol.35 , pp. 992-1019
    • Mulvihill, E.E.1    Drucker, D.J.2
  • 35
    • 84929469873 scopus 로고    scopus 로고
    • Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis
    • Nakashima S, Matsui T, Takeuchi M & Yamagishi SI 2014 Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis. Hormone and Metabolic Research 46 717–721. (doi:10.1055/s-0034-1371892)
    • (2014) Hormone and Metabolic Research , vol.46 , pp. 717-721
    • Nakashima, S.1    Matsui, T.2    Takeuchi, M.3    Yamagishi, S.I.4
  • 37
    • 84871309097 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression
    • Ojima A, Ishibashi Y, Matsui T, Maeda S, Nishino Y, Takeuchi M, Fukami K & Yamagishi S 2013 Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression. American Journal of Pathology 182 132–141. (doi:10.1016/j.ajpath.2012.09.016)
    • (2013) American Journal of Pathology , vol.182 , pp. 132-141
    • Ojima, A.1    Ishibashi, Y.2    Matsui, T.3    Maeda, S.4    Nishino, Y.5    Takeuchi, M.6    Fukami, K.7    Yamagishi, S.8
  • 38
    • 84901303279 scopus 로고    scopus 로고
    • DPP-4 inhibitors-renoprotection in diabetic nephropathy?
    • Panchapakesan U & Pollock CA 2014 DPP-4 inhibitors-renoprotection in diabetic nephropathy? Diabetes 63 1829–1830. (doi:10.2337/db14-0366)
    • (2014) Diabetes , vol.63 , pp. 1829-1830
    • Panchapakesan, U.1    Pollock, C.A.2
  • 40
    • 84871675071 scopus 로고    scopus 로고
    • The glucagon-like peptide-1 receptor – or not?
    • Pyke C & Knudsen LB 2013 The glucagon-like peptide-1 receptor – or not? Endocrinology 154 4–8. (doi:10.1210/en.2012-2124)
    • (2013) Endocrinology , vol.154 , pp. 4-8
    • Pyke, C.1    Knudsen, L.B.2
  • 42
    • 84867136387 scopus 로고    scopus 로고
    • Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice
    • Rieg T, Gerasimova M, Murray F, Masuda T, Tang T, Rose M, Drucker DJ & Vallon V 2012 Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. American Journal of Physiology: Renal Physiology 303 F963–F971. (doi:10.1152/ajpcell.00217.2012)
    • (2012) American Journal of Physiology: Renal Physiology , vol.303 , pp. F963-F971
    • Rieg, T.1    Gerasimova, M.2    Murray, F.3    Masuda, T.4    Tang, T.5    Rose, M.6    Drucker, D.J.7    Vallon, V.8
  • 43
    • 84883560410 scopus 로고    scopus 로고
    • Efficacy of alogliptin, a dipeptidyl peptidase-4 inhibitor, on glucose parameters, the activity of the advanced glycation end product (AGE) – receptor for AGE (RAGE) axis and albuminuria in Japanese type 2 diabetes
    • Sakata K, Hayakawa M, Yano Y, Tamaki N, Yokota N, Eto T, Watanabe R, Hirayama N, Matsuo T, Kuroki K, et al. 2013 Efficacy of alogliptin, a dipeptidyl peptidase-4 inhibitor, on glucose parameters, the activity of the advanced glycation end product (AGE) – receptor for AGE (RAGE) axis and albuminuria in Japanese type 2 diabetes. Diabetes/ Metabolism Research and Reviews 29 624–630. (doi:10.1002/dmrr.2437)
    • (2013) Diabetes/ Metabolism Research and Reviews , vol.29 , pp. 624-630
    • Sakata, K.1    Hayakawa, M.2    Yano, Y.3    Tamaki, N.4    Yokota, N.5    Eto, T.6    Watanabe, R.7    Hirayama, N.8    Matsuo, T.9    Kuroki, K.10
  • 44
    • 70349882090 scopus 로고    scopus 로고
    • Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes
    • Sayyed SG, Hagele H, Kulkarni OP, Endlich K, Segerer S, Eulberg D, Klussmann S & Anders HJ 2009 Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes. Diabetologia 52 2445–2454. (doi:10.1007/s00125-009-1493-6)
    • (2009) Diabetologia , vol.52 , pp. 2445-2454
    • Sayyed, S.G.1    Hagele, H.2    Kulkarni, O.P.3    Endlich, K.4    Segerer, S.5    Eulberg, D.6    Klussmann, S.7    Anders, H.J.8
  • 45
    • 33947584619 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells
    • Schlatter P, Beglinger C, Drewe J & Gutmann H 2007 Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells. Regulatory Peptides 141 120–128. (doi:10.1016/j. regpep.2006.12.016)
    • (2007) Regulatory Peptides , vol.141 , pp. 120-128
    • Schlatter, P.1    Beglinger, C.2    Drewe, J.3    Gutmann, H.4
  • 47
    • 84927640087 scopus 로고    scopus 로고
    • Blood pressure and glucose independent renoprotective effects of dipeptidyl peptidase-4 inhibition in a mouse model of type-2 diabetic nephropathy
    • discussion 2223
    • Sharkovska Y, Reichetzeder C, Alter M, Tsuprykov O, Bachmann S, Secher T, Klein T & Hocher B 2014 Blood pressure and glucose independent renoprotective effects of dipeptidyl peptidase-4 inhibition in a mouse model of type-2 diabetic nephropathy. Journal of Hypertension 32 2211–2223; discussion 2223. (doi:10.1097/HJH.0000000000000328)
    • (2014) Journal of Hypertension , vol.32 , pp. 2211-2223
    • Sharkovska, Y.1    Reichetzeder, C.2    Alter, M.3    Tsuprykov, O.4    Bachmann, S.5    Secher, T.6    Klein, T.7    Hocher, B.8
  • 49
    • 0029785894 scopus 로고    scopus 로고
    • Immunoelectron microscopic single and double labelling of aminopeptidase N (CD 13) and dipeptidyl peptidase IV (CD 26)
    • Stange T, Kettmann U & Holzhausen HJ 1996 Immunoelectron microscopic single and double labelling of aminopeptidase N (CD 13) and dipeptidyl peptidase IV (CD 26). Acta Histochemica 98 323–331. (doi:10.1016/S0065-1281(96)80025-0)
    • (1996) Acta Histochemica , vol.98 , pp. 323-331
    • Stange, T.1    Kettmann, U.2    Holzhausen, H.J.3
  • 50
  • 51
    • 84964689544 scopus 로고    scopus 로고
    • The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy
    • Tsuprykov O, Ando R, Reichetzeder C, von Websky K, Antonenko V, Sharkovska Y, Chaykovska L, Rahnenfuhrer J, Hasan AA, Tammen H, et al. 2016 The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy. Kidney International 89 1049–1061. (doi:10.1016/j.kint.2016.01.016)
    • (2016) Kidney International , vol.89 , pp. 1049-1061
    • Tsuprykov, O.1    Ando, R.2    Reichetzeder, C.3    Von Websky, K.4    Antonenko, V.5    Sharkovska, Y.6    Chaykovska, L.7    Rahnenfuhrer, J.8    Hasan, A.A.9    Tammen, H.10
  • 52
    • 85013989186 scopus 로고    scopus 로고
    • Effects of once-weekly dulaglutide on kidney function in patients with type 2 diabetes in phase II and III clinical trials
    • Tuttle KR, McKinney TD, Davidson JA, Anglin G, Harper KD & Botros FT 2016 Effects of once-weekly dulaglutide on kidney function in patients with type 2 diabetes in phase II and III clinical trials. Diabetes, Obesity and Metabolism 19 436–441. (doi:10.1111/dom.12816)
    • (2016) Diabetes, Obesity and Metabolism , vol.19 , pp. 436-441
    • Tuttle, K.R.1    McKinney, T.D.2    Davidson, J.A.3    Anglin, G.4    Harper, K.D.5    Botros, F.T.6
  • 53
    • 0025344306 scopus 로고
    • CD26 antigen is a surface dipeptidyl peptidase IV (DPPIV) as characterized by monoclonal antibodies clone TII-19–4-7 and 4EL1C7
    • Ulmer AJ, Mattern T, Feller AC, Heymann E & Flad HD 1990 CD26 antigen is a surface dipeptidyl peptidase IV (DPPIV) as characterized by monoclonal antibodies clone TII-19–4-7 and 4EL1C7. Scandinavian Journal of Immunology 31 429–435. (doi:10.1111/j.1365-3083.1990.tb02789.x)
    • (1990) Scandinavian Journal of Immunology , vol.31 , pp. 429-435
    • Ulmer, A.J.1    Mattern, T.2    Feller, A.C.3    Heymann, E.4    Flad, H.D.5
  • 57
    • 84902552092 scopus 로고    scopus 로고
    • Soluble DPP4 originates in part from bone marrow cells and not from the kidney
    • Wang Z, Grigo C, Steinbeck J, von Horsten S, Amann K & Daniel C 2014 Soluble DPP4 originates in part from bone marrow cells and not from the kidney. Peptides 57 109–117. (doi:10.1016/j. peptides.2014.05.006)
    • (2014) Peptides , vol.57 , pp. 109-117
    • Wang, Z.1    Grigo, C.2    Steinbeck, J.3    Von Horsten, S.4    Amann, K.5    Daniel, C.6
  • 58
    • 34447103388 scopus 로고    scopus 로고
    • Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin
    • Yang J, Campitelli J, Hu G, Lin Y, Luo J & Xue C 2007 Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin. Life Science 81 272–279. (doi:10.1016/j. lfs.2007.04.040)
    • (2007) Life Science , vol.81 , pp. 272-279
    • Yang, J.1    Campitelli, J.2    Hu, G.3    Lin, Y.4    Luo, J.5    Xue, C.6
  • 59
    • 85006263584 scopus 로고    scopus 로고
    • Exendin-4 ameliorates lipotoxicity-induced glomerular endothelial cell injury by improving ABC transporter A1-mediated cholesterol efflux in diabetic apoE knockout mice
    • Yin QH, Zhang R, Li L, Wang YT, Liu JP, Zhang J, Bai L, Cheng JQ, Fu P & Liu F 2016 Exendin-4 ameliorates lipotoxicity-induced glomerular endothelial cell injury by improving ABC transporter A1-mediated cholesterol efflux in diabetic apoE knockout mice. Journal of Biological Chemistry 291 26487–26501. (doi:10.1074/jbc.M116.730564)
    • (2016) Journal of Biological Chemistry , vol.291 , pp. 26487-26501
    • Yin, Q.H.1    Zhang, R.2    Li, L.3    Wang, Y.T.4    Liu, J.P.5    Zhang, J.6    Bai, L.7    Cheng, J.Q.8    Fu, P.9    Liu, F.10
  • 60
    • 84940767662 scopus 로고    scopus 로고
    • Evidence for antifibrotic incretin-independent effects of the DPP-4 inhibitor linagliptin
    • Zeisberg M & Zeisberg EM 2015 Evidence for antifibrotic incretin-independent effects of the DPP-4 inhibitor linagliptin. Kidney International 88 429–431. (doi:10.1038/ki.2015.175)
    • (2015) Kidney International , vol.88 , pp. 429-431
    • Zeisberg, M.1    Zeisberg, E.M.2


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