Membrane engineering - A novel strategy to enhance the production and accumulation of β-carotene in Escherichia coli

Metabolic Engineering

Volumn 43, Issue , 2017, Pages 85-91

  Wu, Tao ^a,b,c   Ye, Lijun ^a,b   Zhao, Dongdong ^a,b   Li, Siwei ^a,b   Li, Qingyan ^a,b   Zhang, Bolin ^c   Bi, Changhao ^a,b   Zhang, Xueli ^a,b  

^a Chinese Academy of Sciences   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c BEIJING FORESTRY UNIVERSITY   (China)

Author keywords

Escherichia coli; Membrane engineering; Production; Terpenoids; Carotene

Indexed keywords

BIOSYNTHESIS; CELLS; CYTOLOGY; ESCHERICHIA COLI; HYDROPHOBICITY; PRODUCTION; STRAIN; TERPENES;

BIOLOGICAL FUNCTIONS; ELECTRON MICROSCOPY IMAGES; HYDROPHOBIC COMPOUNDS; MEMBRANE ENGINEERINGS; MEMBRANE SEPARATION; MICROBIAL CELL FACTORIES; MORPHOLOGICAL CHANGES; TERPENOIDS;

MEMBRANES;

BETA CAROTENE; ESCHERICHIA COLI PROTEIN; MEMBRANE PROTEIN;

ARTICLE; BACTERIAL CELL; BACTERIAL CHROMOSOME; BACTERIAL STRAIN; BACTERIUM CULTURE; BIOTECHNOLOGICAL PRODUCTION; CELL MEMBRANE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ESCHERICHIA COLI; METABOLIC ENGINEERING; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS; BIOSYNTHESIS; GENETIC ENGINEERING; GENETICS; METABOLISM;

BETA CAROTENE; CELL MEMBRANE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENETIC ENGINEERING; MEMBRANE PROTEINS;

EID: 85024840263     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.07.001     Document Type: Article

References (32)

1. Ahrazem, O., Rubio-Moraga, A., Berman, J., Capell, T., Christou, P., Zhu, C., Gomez-Gomez, L., The carotenoid cleavage dioxygenase CCD2 catalysing the synthesis of crocetin in spring crocuses and saffron is a plastidial enzyme. New Phytol. 209 (2016), 650–663.
2. Ajikumar, P.K., Tyo, K., Carlsen, S., Mucha, O., Phon, T.H., Stephanopoulos, G., Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms. Mol. Pharm. 5 (2008), 167–190.
3. Albermann, C., Trachtmann, N., Sprenger, G.A., A simple and reliable method to conduct and monitor expression cassette integration into the Escherichia coli chromosome. Biotechnol. J. 5 (2010), 32–38.
4. Alper, H., Fischer, C., Nevoigt, E., Stephanopoulos, G., Tuning genetic control through promoter engineering. Proc. Natl. Acad. Sci. USA 102 (2005), 12678–12683.
5. Arechaga, I., Miroux, B., Karrasch, S., Huijbregts, R., de Kruijff, B., Runswick, M.J., Walker, J.E., Characterisation of new intracellular membranes in Escherichia coli accompanying large scale over-production of the b subunit of F(1)F(o) ATP synthase. FEBS Lett. 482 (2000), 215–219.
6. Bernales, S., Mcdonald, K.L., Walter, P., Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol., 4, 2006, e423.
7. Choi, H.S., Lee, S.Y., Kim, T.Y., Woo, H.M., In silico identification of gene amplification targets for improvement of lycopene production. Appl. Environ. Microbiol. 76 (2010), 3097–3105.
8. Cronan, J.E. Jr., Rock, C.O., Biosynthesis of membrane lipids. EcoSal Plus, 2008, 3.
9. Das, A., Yoon, S.H., Lee, S.H., Kim, J.Y., Oh, D.K., Kim, S.W., An update on microbial carotenoid production: application of recent metabolic engineering tools. Appl. Microbiol. Biotechnol. 77 (2007), 505–512.
10. Eriksson, H.M., Wessman, P., Ge, C., Edwards, K., Wieslander, A., Massive formation of intracellular membrane vesicles in Escherichia coli by a monotopic membrane-bound lipid glycosyltransferase. J. Biol. Chem. 284 (2009), 33904–33914.
11. Herskovits, A.A., Shimoni, E., Minsky, A., Bibi, E., Accumulation of endoplasmic membranes and novel membrane-bound ribosome-signal recognition particle receptor complexes in Escherichia coli. J. Cell Biol. 159 (2002), 403–410.
12. Hillson, N.J., Rosengarten, R.D., Keasling, J.D., j5 DNA assembly design automation software. ACS Synth. Biol. 1 (2012), 14–21.
13. Janssen, H.J., Steinbuchel, A., Production of triacylglycerols in Escherichia coli by deletion of the diacylglycerol kinase gene and heterologous overexpression of atfA from Acinetobacter baylyi ADP1. Appl. Microbiol. Biotechnol. 98 (2014), 1913–1924.
14. Jin, Y.S., Stephanopoulos, G., Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab. Eng. 9 (2007), 337–347.
15. Lee, P.C., Schmidt-Dannert, C., Metabolic engineering towards biotechnological production of carotenoids in microorganisms. Appl. Microbiol. Biotechnol. 60 (2002), 1–11.
16. Li, Y., Lin, Z., Huang, C., Zhang, Y., Wang, Z., Tang, Y.-j., Chen, T., Zhao, X., Metabolic engineering of Escherichia coli using CRISPR–Cas9 meditated genome editing. Metab. Eng. 31 (2015), 13–21.
17. Lu, J., Tang, J., Liu, Y., Zhu, X., Zhang, T., Zhang, X., Combinatorial modulation of galP and glk gene expression for improved alternative glucose utilization. Appl. Microbiol. Biotechnol. 93 (2012), 2455–2462.
18. Lu, P., Ma, D., Yan, C., Gong, X., Du, M., Shi, Y., Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase. Proc. Natl. Acad. Sci. USA 111 (2014), 1813–1818.
19. Martin, V.J., Pitera, D.J., Withers, S.T., Newman, J.D., Keasling, J.D., Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat. Biotechnol. 21 (2003), 796–802.
20. Nam, H.-K., Choi, J.-G., Lee, J.-H., Kim, S.-W., Oh, D.-K., Increase in the production of β-carotene in recombinant Escherichia coli cultured in a chemically defined medium supplemented with amino acids. Biotechnol. Lett. 35 (2013), 265–271.
21. Palozza, P., Krinsky, N.I., Antioxidant effects of carotenoids in vivo and in vitro: an overview. Methods Enzymol. 213 (1992), 403–420.
22. Röttig, A., Zurek, P.J., Steinbüchel, A., Assessment of bacterial acyltransferases for an efficient lipid production in metabolically engineered strains of E. coli. Metab. Eng. 32 (2015), 195–206.
23. Van Weeghel, R.P., Keck, W., Robillard, G.T., Regulated high-level expression of the mannitol permease of the phosphoenolpyruvate-dependent sugar phosphotransferase system in Escherichia coli. Proc. Natl. Acad. Sci. USA 87 (1990), 2613–2617.
24. Von Meyenburg, K., Jorgensen, B.B., van Deurs, B., Physiological and morphological effects of overproduction of membrane-bound ATP synthase in Escherichia coli K-12. Embo J. 3 (1984), 1791–1797.
25. Wang, J., Guleria, S., Koffas, M.A.G., Yan, Y., Microbial production of value-added nutraceuticals. Curr. Opin. Biotechnol. 37 (2016), 97–104.
26. Weiner, J.H., Lemire, B.D., Elmes, M.L., Bradley, R.D., Scraba, D.G., Overproduction of fumarate reductase in Escherichia coli induces a novel intracellular lipid-protein organelle. J. Bacteriol. 158 (1984), 590–596.
27. Yang, J., Guo, L., Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways. Microb. Cell Factor., 13, 2014, 160.
28. Yoon, S.H., Lee, S.H., Das, A., Ryu, H.K., Jang, H.J., Kim, J.Y., Oh, D.K., Keasling, J.D., Kim, S.W., Combinatorial expression of bacterial whole mevalonate pathway for the production of beta-carotene in E. coli. J. Biotechnol. 140 (2009), 218–226.
29. Yoon, S.H., Park, H.M., Kim, J.E., Lee, S.H., Choi, M.S., Kim, J.Y., Oh, D.K., Keasling, J.D., Kim, S.W., Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. Biotechnol. Prog. 23 (2007), 599–605.
30. Yuan, L.Z., Rouviere, P.E., Larossa, R.A., Suh, W., Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli. Metab. Eng. 8 (2006), 79–90.
31. Zhao, D., Yuan, S., Xiong, B., Sun, H., Ye, L., Li, J., Zhang, X., Bi, C. Development of a Fast and Easy Method for Escherichia Coli Genome Editing with CRISPR/Cas9.2016,15, 205.
32. Zhao, J., Li, Q., Sun, T., Zhu, X., Xu, H., Tang, J., Zhang, X., Ma, Y., Engineering central metabolic modules of Escherichia coli for improving beta-carotene production. Metab. Eng. 17 (2013), 42–50.