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Volumn 18, Issue 10, 2017, Pages 931-943

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

(46)  Farzan, Niloufar a,b   Vijverberg, Susanne J a,b   Andiappan, Anand K c   Arianto, Lambang d   Berce, Vojko e,f   Blanca López, Natalia g   Bisgaard, Hans d   Bønnelykke, Klaus d   Burchard, Esteban G h   Campo, Paloma i   Canino, Glorisa j   Carleton, Bruce k   Celedón, Juan C l   Chew, Fook Tim m,ai   Chiang, Wen Chin m,ai   Cloutier, Michelle M n   Daley, Denis k   Den Dekker, Herman T o   Dijk, F Nicole p,q   Duijts, Liesbeth o   more..


Author keywords

asthma; children; consortium; genetics; pharmacogenomics; treatment

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; LEUKOTRIENE RECEPTOR BLOCKING AGENT; ANTIASTHMATIC AGENT;

EID: 85024501836     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs-2017-0035     Document Type: Article
Times cited : (25)

References (60)
  • 2
    • 2342590065 scopus 로고    scopus 로고
    • The global burden of asthma: Executive summary of the GINA Dissemination Committee report
    • Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 59(5), 469-478 (2004).
    • (2004) Allergy , vol.59 , Issue.5 , pp. 469-478
    • Masoli, M.1    Fabian, D.2    Holt, S.3    Beasley, R.4
  • 3
    • 0036126690 scopus 로고    scopus 로고
    • Significant variability in response to inhaled corticosteroids for persistent asthma
    • Szefler SJ, Martin RJ, King TS et al. Significant variability in response to inhaled corticosteroids for persistent asthma. J. Allergy Clin. Immunol. 109(3), 410-418 (2002).
    • (2002) J. Allergy Clin. Immunol. , vol.109 , Issue.3 , pp. 410-418
    • Szefler, S.J.1    Martin, R.J.2    King, T.S.3
  • 4
    • 13444254245 scopus 로고    scopus 로고
    • Characterization of within-subject responses to fluticasone and montelukast in childhood asthma
    • Szefler SJ, Phillips BR, Martinez FD et al. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma. J. Allergy Clin. Immunol. 115(2), 233-242 (2005).
    • (2005) J. Allergy Clin. Immunol. , vol.115 , Issue.2 , pp. 233-242
    • Szefler, S.J.1    Phillips, B.R.2    Martinez, F.D.3
  • 5
    • 0033574195 scopus 로고    scopus 로고
    • Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma. A randomized, controlled trial. Montelukast/Beclomethasone Study Group
    • Malmstrom K, Rodriguez-Gomez G, Guerra J et al. Oral montelukast, inhaled beclomethasone, and placebo for chronic asthma. A randomized, controlled trial. Montelukast/Beclomethasone Study Group. Ann. Intern. Med. Mar. 130(6), 487-495 (1999).
    • (1999) Ann. Intern. Med. Mar. , vol.130 , Issue.6 , pp. 487-495
    • Malmstrom, K.1    Rodriguez-Gomez, G.2    Guerra, J.3
  • 6
    • 74549125654 scopus 로고    scopus 로고
    • Heterogeneity of response to asthma controller therapy: Clinical implications
    • Langmack EL, Martin RJ. Heterogeneity of response to asthma controller therapy: clinical implications. Curr. Opin. Pulm. Med. 16(1), 13-18 (2010).
    • (2010) Curr. Opin. Pulm. Med. , vol.16 , Issue.1 , pp. 13-18
    • Langmack, E.L.1    Martin, R.J.2
  • 8
    • 40649100801 scopus 로고    scopus 로고
    • Suboptimal asthma control: Prevalence, detection and consequences in general practice
    • Chapman KR, Boulet LP, Rea RM, Franssen E. Suboptimal asthma control: prevalence, detection and consequences in general practice. Eur. Respir. J. 31(2), 320-325 (2008).
    • (2008) Eur. Respir. J. , vol.31 , Issue.2 , pp. 320-325
    • Chapman, K.R.1    Boulet, L.P.2    Rea, R.M.3    Franssen, E.4
  • 9
    • 33845968717 scopus 로고    scopus 로고
    • Cost of scheduled and unscheduled asthma management in seven European Union countries
    • Williams AE, Lloyd AC, Watson L, Rabe KF. Cost of scheduled and unscheduled asthma management in seven European Union countries. Eur. Respir. Rev. 15(98), 4-9 (2006).
    • (2006) Eur. Respir. Rev. , vol.15 , Issue.98 , pp. 4-9
    • Williams, A.E.1    Lloyd, A.C.2    Watson, L.3    Rabe, K.F.4
  • 12
    • 84925607568 scopus 로고    scopus 로고
    • Personalized medicine in children with asthma
    • Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr. Respir. Rev. 16(2), 101-107 (2015).
    • (2015) Paediatr. Respir. Rev. , vol.16 , Issue.2 , pp. 101-107
    • Pijnenburg, M.W.1    Szefler, S.2
  • 13
    • 84896716139 scopus 로고    scopus 로고
    • Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids
    • Park H-W, Dahlin A, Tse S et al. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J. Allergy Clin. Immunol. 133(3), 664.e5-669.e5 (2014).
    • (2014) J. Allergy Clin. Immunol. , vol.133 , Issue.3 , pp. 664e5-669e5
    • Park, H.-W.1    Dahlin, A.2    Tse, S.3
  • 14
    • 70649097378 scopus 로고    scopus 로고
    • Predictors of poor response during asthma therapy differ with definition of outcome
    • Rogers AJ, Tantisira KG, Fuhlbrigge AL et al. Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics 10(8), 1231-1242 (2009).
    • (2009) Pharmacogenomics , vol.10 , Issue.8 , pp. 1231-1242
    • Rogers, A.J.1    Tantisira, K.G.2    Fuhlbrigge, A.L.3
  • 15
    • 79960429165 scopus 로고    scopus 로고
    • Predictors of symptoms are different from predictors of severe exacerbations from asthma in children
    • Wu AC, Tantisira K, Li L, Schuemann B, Weiss ST, Fuhlbrigge AL. Predictors of symptoms are different from predictors of severe exacerbations from asthma in children. Chest 140(1), 100-107 (2011).
    • (2011) Chest , vol.140 , Issue.1 , pp. 100-107
    • Wu, A.C.1    Tantisira, K.2    Li, L.3    Schuemann, B.4    Weiss, S.T.5    Fuhlbrigge, A.L.6
  • 16
    • 2642570170 scopus 로고    scopus 로고
    • Moving towards individualized medicine with pharmacogenomics
    • Evans WE, Relling MV. Moving towards individualized medicine with pharmacogenomics. Nature 429(6990), 464-468 (2004).
    • (2004) Nature , vol.429 , Issue.6990 , pp. 464-468
    • Evans, W.E.1    Relling, M.V.2
  • 17
  • 18
    • 84940770259 scopus 로고    scopus 로고
    • The Study Team for Early Life Asthma Research (STELAR) consortium "asthma e-lab": Team science bringing data, methods and investigators together
    • Custovic A, Ainsworth J, Arshad H et al. The Study Team for Early Life Asthma Research (STELAR) consortium "Asthma e-lab": team science bringing data, methods and investigators together. Thorax 70(8), 799-801 (2015).
    • (2015) Thorax , vol.70 , Issue.8 , pp. 799-801
    • Custovic, A.1    Ainsworth, J.2    Arshad, H.3
  • 19
    • 36649003702 scopus 로고    scopus 로고
    • Diagnosis and treatment of asthma in childhood: A PRACTALL consensus report
    • Bacharier LB, Boner A, Carlsen K-H et al. Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy 63(1), 5-34 (2008).
    • (2008) Allergy , vol.63 , Issue.1 , pp. 5-34
    • Bacharier, L.B.1    Boner, A.2    Carlsen, K.-H.3
  • 20
    • 85024475714 scopus 로고    scopus 로고
    • Pica consortium. www.pica-consortium.org
  • 21
  • 22
    • 67649805319 scopus 로고    scopus 로고
    • An official American Thoracic Society/European Respiratory Society statement: Asthma control and exacerbations: Standardizing endpoints for clinical asthma trials and clinical practice
    • Reddel HK, Taylor DR, Bateman ED et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am. J. Respir. Crit. Care Med. 180(1), 59-99 (2009).
    • (2009) Am. J. Respir. Crit. Care Med. , vol.180 , Issue.1 , pp. 59-99
    • Reddel, H.K.1    Taylor, D.R.2    Bateman, E.D.3
  • 23
    • 49449101148 scopus 로고    scopus 로고
    • Discrepancy between clinical asthma control assessment tools and fractional exhaled nitric oxide
    • Khalili B, Boggs PB, Shi R, Bahna SL. Discrepancy between clinical asthma control assessment tools and fractional exhaled nitric oxide. Ann. Allergy Asthma Immunol. 101(2), 124-129 (2008).
    • (2008) Ann. Allergy Asthma Immunol. , vol.101 , Issue.2 , pp. 124-129
    • Khalili, B.1    Boggs, P.B.2    Shi, R.3    Bahna, S.L.4
  • 24
    • 18544372466 scopus 로고    scopus 로고
    • Understanding interobserver agreement: The kappa statistic
    • Viera AJ, Garrett JM. Understanding interobserver agreement: the kappa statistic. Fam. Med. 37(5), 360-363 (2005).
    • (2005) Fam. Med. , vol.37 , Issue.5 , pp. 360-363
    • Viera, A.J.1    Garrett, J.M.2
  • 25
    • 84907095419 scopus 로고    scopus 로고
    • R: A language and environment for statistical computing
    • Vienna, Austria
    • R Development Core Team (2008). R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. www.R-project.org
    • (2008) R Foundation for Statistical Computing
  • 26
    • 80052721297 scopus 로고    scopus 로고
    • Identification of IL6R and chromosome 11q13.5 as risk loci for asthma
    • Ferreira MAR, Matheson MC, Duffy DL et al. Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet 378(9795), 1006-1014 (2011).
    • (2011) Lancet , vol.378 , Issue.9795 , pp. 1006-1014
    • Ferreira, M.A.R.1    Matheson, M.C.2    Duffy, D.L.3
  • 27
    • 33750302641 scopus 로고    scopus 로고
    • Arginine-16 beta2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol
    • Palmer CNA, Lipworth BJ, Lee S, Ismail T, Macgregor DF, Mukhopadhyay S. Arginine-16 beta2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol. Thorax 61(11), 940-944 (2006).
    • (2006) Thorax , vol.61 , Issue.11 , pp. 940-944
    • Palmer, C.N.A.1    Lipworth, B.J.2    Lee, S.3    Ismail, T.4    Macgregor, D.F.5    Mukhopadhyay, S.6
  • 28
    • 0041670812 scopus 로고    scopus 로고
    • Strategies for preventing wheezing and asthma in small children
    • Wickman M, Melén E, Berglind N et al. Strategies for preventing wheezing and asthma in small children. Allergy 58(8), 742-747 (2003).
    • (2003) Allergy , vol.58 , Issue.8 , pp. 742-747
    • Wickman, M.1    Melén, E.2    Berglind, N.3
  • 29
    • 0033012176 scopus 로고    scopus 로고
    • The Childhood Asthma Management Program (CAMP): Design, rationale, and methods. Childhood Asthma Management Program Research Group
    • The Childhood Asthma Management Program (CAMP): design, rationale, and methods. Childhood Asthma Management Program Research Group. Control Clin. Trials 20(1), 91-120 (1999).
    • (1999) Control Clin. Trials , vol.20 , Issue.1 , pp. 91-120
  • 30
    • 6044229549 scopus 로고    scopus 로고
    • The Copenhagen Prospective Study on Asthma in Childhood (COPSAC): Design, rationale, and baseline data from a longitudinal birth cohort study
    • Bisgaard H. The Copenhagen Prospective Study on Asthma in Childhood (COPSAC): design, rationale, and baseline data from a longitudinal birth cohort study. Ann. Allergy Asthma Immunol. 93(4), 381-389 (2004).
    • (2004) Ann. Allergy Asthma Immunol. , vol.93 , Issue.4 , pp. 381-389
    • Bisgaard, H.1
  • 31
    • 34547216747 scopus 로고    scopus 로고
    • Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
    • Moffatt MF, Kabesch M, Liang L et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448(7152), 470-473 (2007).
    • (2007) Nature , vol.448 , Issue.7152 , pp. 470-473
    • Moffatt, M.F.1    Kabesch, M.2    Liang, L.3
  • 32
    • 84881135063 scopus 로고    scopus 로고
    • Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies
    • Nishimura KK, Galanter JM, Roth LA et al. Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies. Am. J. Respir. Crit. Care Med. 188(3), 309-318 (2013).
    • (2013) Am. J. Respir. Crit. Care Med. , vol.188 , Issue.3 , pp. 309-318
    • Nishimura, K.K.1    Galanter, J.M.2    Roth, L.A.3
  • 33
    • 84857923980 scopus 로고    scopus 로고
    • Fetal and infant growth and asthma symptoms in preschool children: The Generation R Study
    • Sonnenschein-van der Voort AMM, Jaddoe VW, Raat H et al. Fetal and infant growth and asthma symptoms in preschool children: the Generation R Study. Am. J. Respir. Crit. Care Med. 185(7), 731-737 (2012).
    • (2012) Am. J. Respir. Crit. Care Med. , vol.185 , Issue.7 , pp. 731-737
    • Sonnenschein-Van Der Voort, A.M.M.1    Jaddoe, V.W.2    Raat, H.3
  • 34
    • 84856463195 scopus 로고    scopus 로고
    • IL-1 receptor-associated kinase 3 gene (IRAK3) variants associate with asthma in a replication study in the Spanish population
    • 575.e1-575.e10
    • Pino-Yanes M, Sánchez-Machín I, Cumplido J et al. IL-1 receptor-associated kinase 3 gene (IRAK3) variants associate with asthma in a replication study in the Spanish population. J. Allergy Clin. Immunol. 129(2), 573-575, 575.e1-575.e10 (2012).
    • (2012) J. Allergy Clin. Immunol. , vol.129 , Issue.2 , pp. 573-575
    • Pino-Yanes, M.1    Sánchez-Machín, I.2    Cumplido, J.3
  • 35
    • 70649108806 scopus 로고    scopus 로고
    • Pharmacogenetics of anti-inflammatory treatment in children with asthma: Rationale and design of the PACMAN cohort
    • Koster ES, Raaijmakers JAM, Koppelman GH et al. Pharmacogenetics of anti-inflammatory treatment in children with asthma: rationale and design of the PACMAN cohort. Pharmacogenomics 10(8), 1351-1361 (2009).
    • (2009) Pharmacogenomics , vol.10 , Issue.8 , pp. 1351-1361
    • Koster, E.S.1    Raaijmakers, J.A.M.2    Koppelman, G.H.3
  • 36
    • 78649713360 scopus 로고    scopus 로고
    • A methodology to establish a database to study gene environment interactions for childhood asthma
    • Turner SW, Ayres JG, Macfarlane TV et al. A methodology to establish a database to study gene environment interactions for childhood asthma. BMC Med. Res. Methodol. 10, 107 (2010).
    • (2010) BMC Med. Res. Methodol. , vol.10 , pp. 107
    • Turner, S.W.1    Ayres, J.G.2    Macfarlane, T.V.3
  • 37
    • 84962607767 scopus 로고    scopus 로고
    • Adrenal responses to a low-dose short synacthen test in children with asthma
    • Hawcutt DB, Jorgensen AL, Wallin N et al. Adrenal responses to a low-dose short synacthen test in children with asthma. Clin. Endocrinol. (Oxf.) 84(5), 793 (2016).
    • (2016) Clin. Endocrinol. (Oxf.) , vol.84 , Issue.5 , pp. 793
    • Hawcutt, D.B.1    Jorgensen, A.L.2    Wallin, N.3
  • 38
    • 77249148898 scopus 로고    scopus 로고
    • Asthma therapy during the first 8 years of life: A PIAMA cohort study
    • Zuidgeest MGP, Koster ES, Maitland-van der Zee A-H et al. Asthma therapy during the first 8 years of life: a PIAMA cohort study. J. Asthma 47(2), 209-213 (2010).
    • (2010) J. Asthma , vol.47 , Issue.2 , pp. 209-213
    • Zuidgeest, M.G.P.1    Koster, E.S.2    Maitland-Van Der Zee, A.-H.3
  • 39
    • 84973563197 scopus 로고    scopus 로고
    • Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis
    • Andiappan AK, Sio YY, Lee B et al. Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis. J. Allergy Clin. Immunol. 137(3), 758.e3-766.e3 (2016).
    • (2016) J. Allergy Clin. Immunol. , vol.137 , Issue.3 , pp. 758e3-766e3
    • Andiappan, A.K.1    Sio, Y.Y.2    Lee, B.3
  • 40
    • 84888130450 scopus 로고    scopus 로고
    • Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma
    • Berce V, Kozmus CEP, Potočnik U. Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma. Pharmacogenomics J. 13(6), 523-529 (2013).
    • (2013) Pharmacogenomics J. , vol.13 , Issue.6 , pp. 523-529
    • Berce, V.1    Kozmus, C.E.P.2    Potočnik, U.3
  • 41
    • 0018068101 scopus 로고
    • Epidemiology Standardization Project (American Thoracic Society)
    • Ferris BG. Epidemiology Standardization Project (American Thoracic Society). Am Rev. Respir. Dis. 118(6 Pt 2), 1-120 (1978).
    • (1978) Am Rev. Respir. Dis. , vol.118 , Issue.6 , pp. 1-120
    • Ferris, B.G.1
  • 43
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han B, Eskin E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet. 88(5), 586-598 (2011).
    • (2011) Am. J. Hum. Genet. , vol.88 , Issue.5 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 44
    • 84988441568 scopus 로고    scopus 로고
    • Genetic association studies in thorax
    • Hall IP, Blakey JD. Genetic association studies in thorax. Thorax 60(5), 357-359 (2005).
    • (2005) Thorax , vol.60 , Issue.5 , pp. 357-359
    • Hall, I.P.1    Blakey, J.D.2
  • 45
    • 84946615672 scopus 로고    scopus 로고
    • The burden of severe asthma in childhood and adolescence: Results from the paediatric U-BIOPRED cohorts
    • Fleming L, Murray C, Bansal AT et al. The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts. Eur. Respir. J. 46(5), 1322-1333 (2015).
    • (2015) Eur. Respir. J. , vol.46 , Issue.5 , pp. 1322-1333
    • Fleming, L.1    Murray, C.2    Bansal, A.T.3
  • 46
    • 80053370268 scopus 로고    scopus 로고
    • Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma
    • Tantisira KG, Lasky-Su J, Harada M et al. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N. Engl. J. Med. 365(13), 1173-1183 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , Issue.13 , pp. 1173-1183
    • Tantisira, K.G.1    Lasky-Su, J.2    Harada, M.3
  • 47
    • 84896716139 scopus 로고    scopus 로고
    • Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids
    • e5
    • Park HW, Dahlin A, Tse S et al. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J. Allergy Clin. Immunol. 133(3), 664-669.e5 (2014).
    • (2014) J. Allergy Clin. Immunol. , vol.133 , Issue.3 , pp. 664-669
    • Park, H.W.1    Dahlin, A.2    Tse, S.3
  • 48
    • 84862585029 scopus 로고    scopus 로고
    • Genomewide association identifies the T gene as a novel asthma pharmacogenetic locus
    • Tantisira KG, Damask A, Szefler SJ et al. Genomewide association identifies the T gene as a novel asthma pharmacogenetic locus. Am. J. Respir. Crit. Care Med. 185(12), 1286-1291 (2012).
    • (2012) Am. J. Respir. Crit. Care Med. , vol.185 , Issue.12 , pp. 1286-1291
    • Tantisira, K.G.1    Damask, A.2    Szefler, S.J.3
  • 49
    • 84891790401 scopus 로고    scopus 로고
    • The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
    • Hindorff L, Parkinson H, Welter D et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 42, D1001-D1006 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D1001-D1006
    • Hindorff, L.1    Parkinson, H.2    Welter, D.3
  • 50
    • 84889016425 scopus 로고    scopus 로고
    • Arg16 ADRB2 genotype increases the risk of asthma exacerbation in children with a reported use of longacting β2-agonists: Results of the PACMAN cohort
    • Zuurhout MJL, Vijverberg SJH, Raaijmakers JAM et al. Arg16 ADRB2 genotype increases the risk of asthma exacerbation in children with a reported use of longacting β2-agonists: results of the PACMAN cohort. Pharmacogenomics 14(16), 1965-1971 (2013).
    • (2013) Pharmacogenomics , vol.14 , Issue.16 , pp. 1965-1971
    • Zuurhout, M.J.L.1    Vijverberg, S.J.H.2    Raaijmakers, J.A.M.3
  • 51
    • 70449652591 scopus 로고    scopus 로고
    • Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): A genotype-stratified, randomised, placebo-controlled, crossover trial
    • Wechsler ME, Kunselman SJ, Chinchilli VM et al. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet 374(9703), 1754-1764 (2009).
    • (2009) Lancet , vol.374 , Issue.9703 , pp. 1754-1764
    • Wechsler, M.E.1    Kunselman, S.J.2    Chinchilli, V.M.3
  • 52
    • 84953231094 scopus 로고    scopus 로고
    • Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: A meta-analysis stratified by treatment
    • Turner S, Francis B, Vijverberg S et al. Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: a meta-analysis stratified by treatment. J. Allergy Clin. Immunol. 138(1), 107-113 (2016).
    • (2016) J. Allergy Clin. Immunol. , vol.138 , Issue.1 , pp. 107-113
    • Turner, S.1    Francis, B.2    Vijverberg, S.3
  • 53
    • 46949102935 scopus 로고    scopus 로고
    • Severe exacerbations in children with mild asthma: Characterizing a pediatric phenotype
    • Carroll CL, Schramm CM, Zucker AR. Severe exacerbations in children with mild asthma: characterizing a pediatric phenotype. J. Asthma. 45(6), 513-517 (2008).
    • (2008) J. Asthma. , vol.45 , Issue.6 , pp. 513-517
    • Carroll, C.L.1    Schramm, C.M.2    Zucker, A.R.3
  • 54
    • 84929245116 scopus 로고    scopus 로고
    • Genetic variation in uncontrolled childhood asthma despite ICS treatment
    • Leusink M, Vijverberg SJH, Koenderman L et al. Genetic variation in uncontrolled childhood asthma despite ICS treatment. Pharmacogenomics J. 16(2), 158-168 (2015).
    • (2015) Pharmacogenomics J. , vol.16 , Issue.2 , pp. 158-168
    • Leusink, M.1    Vijverberg, S.J.H.2    Koenderman, L.3
  • 55
    • 84901983744 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids
    • Vijverberg SJH, Tavendale R, Leusink M et al. Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids. Pharmacogenomics 15(6), 799-806 (2014).
    • (2014) Pharmacogenomics , vol.15 , Issue.6 , pp. 799-806
    • Vijverberg, S.J.H.1    Tavendale, R.2    Leusink, M.3
  • 56
    • 84892663006 scopus 로고    scopus 로고
    • Clinical and epidemiologic phenotypes of childhood asthma
    • Depner M, Fuchs O, Genuneit J et al. Clinical and epidemiologic phenotypes of childhood asthma. Am. J. Respir. Crit. Care Med. 189(2), 129-138 (2013).
    • (2013) Am. J. Respir. Crit. Care Med. , vol.189 , Issue.2 , pp. 129-138
    • Depner, M.1    Fuchs, O.2    Genuneit, J.3
  • 57
    • 42049109764 scopus 로고    scopus 로고
    • PharmGKB and the international warfarin pharmacogenetics consortium: The changing role for pharmacogenomic databases and singledrug pharmacogenetics
    • Owen RP, Altman RB, Klein TE. PharmGKB and the international warfarin pharmacogenetics consortium: the changing role for pharmacogenomic databases and singledrug pharmacogenetics. Hum. Mutat. 29(4), 456-460 (2008).
    • (2008) Hum. Mutat. , vol.29 , Issue.4 , pp. 456-460
    • Owen, R.P.1    Altman, R.B.2    Klein, T.E.3
  • 58
    • 84856283235 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
    • Paternoster L, Standl M, Chen CM et al. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat. Genet. 44(2), 187-192 (2012).
    • (2012) Nat. Genet. , vol.44 , Issue.2 , pp. 187-192
    • Paternoster, L.1    Standl, M.2    Chen, C.M.3
  • 59
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • Moffatt MF, Gut IG, Demenais F et al. A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 363(13), 1211-1221 (2010).
    • (2010) N. Engl. J. Med. , vol.363 , Issue.13 , pp. 1211-1221
    • Moffatt, M.F.1    Gut, I.G.2    Demenais, F.3
  • 60
    • 85014079519 scopus 로고    scopus 로고
    • Genome-wide interaction study of dust mite allergen on lung function in children with asthma
    • Forno E, Sordillo J, Brehm J et al. Genome-wide interaction study of dust mite allergen on lung function in children with asthma. J Allergy Clin Immunol pii: S0091-6749(17), 30154-30159 (2016).
    • (2016) J Allergy Clin Immunol , pp. 30154-30159
    • Forno, E.1    Sordillo, J.2    Brehm, J.3


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