-
1
-
-
0031857508
-
Clinical pharmacology of antiar-rhythmic drugs
-
Capucci A, Aschieri D, and Villani GQ (1998) Clinical pharmacology of antiar-rhythmic drugs. Drugs Aging 13:51–70.
-
(1998)
Drugs Aging
, vol.13
, pp. 51-70
-
-
Capucci, A.1
Aschieri, D.2
Villani, G.Q.3
-
2
-
-
34047102944
-
Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells
-
Chen N and Reith ME (2007) Substrates and inhibitors display different sensitivity to expression level of the dopamine transporter in heterologously expressing cells. J Neurochem 101:377–388.
-
(2007)
J Neurochem
, vol.101
, pp. 377-388
-
-
Chen, N.1
Reith, M.E.2
-
3
-
-
84910072268
-
Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOat3
-
Chioukh R, Noel-Hudson MS, Ribes S, Fournier N, Becquemont L, and Verstuyft C (2014) Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3. Drug Metab Dispos 42:2041–2048.
-
(2014)
Drug Metab Dispos
, vol.42
, pp. 2041-2048
-
-
Chioukh, R.1
Noel-Hudson, M.S.2
Ribes, S.3
Fournier, N.4
Becquemont, L.5
Verstuyft, C.6
-
4
-
-
34247236764
-
Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4c1, and multidrug resistance p-glycoprotein
-
Chu XY, Bleasby K, Yabut J, Cai X, Chan GH, Hafey MJ, Xu S, Bergman AJ, Braun MP, Dean DC, et al. (2007) Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein. J Pharmacol Exp Ther 321:673–683.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 673-683
-
-
Chu, X.Y.1
Bleasby, K.2
Yabut, J.3
Cai, X.4
Chan, G.H.5
Hafey, M.J.6
Xu, S.7
Bergman, A.J.8
Braun, M.P.9
Dean, D.C.10
-
5
-
-
84868583572
-
Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: Discovery and molecular characterization
-
Duan P, Li S, Ai N, Hu L, Welsh WJ, and You G (2012) Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization. Mol Pharm 9:3340–3346.
-
(2012)
Mol Pharm
, vol.9
, pp. 3340-3346
-
-
Duan, P.1
Li, S.2
Ai, N.3
Hu, L.4
Welsh, W.J.5
You, G.6
-
6
-
-
84865415281
-
-
Center for Drug Evaluation and Research (CDER) (U.S. Department of Health and Human Services, Food and Drug Administration, Rockville, MD
-
Center for Drug Evaluation and Research (CDER) (2012) Guidance for Industry: Drug Interaction Studies — Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations U.S. Department of Health and Human Services, Food and Drug Administration, Rockville, MD.
-
(2012)
Guidance for Industry: Drug Interaction Studies — Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations
-
-
-
7
-
-
0022371866
-
Effect of nicardipine in elderly hypertensive patients
-
Forette F, Bellet M, Henry JF, Hervy MP, Poyard-Salmeron C, Bouchacourt P, and Guerret M (1985) Effect of nicardipine in elderly hypertensive patients. Br J Clin Pharmacol 20 (Suppl 1):125S–129S.
-
(1985)
Br J Clin Pharmacol
, vol.20
, pp. 125S-129S
-
-
Forette, F.1
Bellet, M.2
Henry, J.F.3
Hervy, M.P.4
Poyard-Salmeron, C.5
Bouchacourt, P.6
Guerret, M.7
-
8
-
-
84982121530
-
Pharmacokinetic profiles of significant adverse events with crizotinib in japanese patients with abcb1 polymorphism
-
Fujiwara Y, Hamada A, Mizugaki H, Aikawa H, Hata T, Horinouchi H, Kanda S, Goto Y, Itahashi K, Nokihara H, et al. (2016) Pharmacokinetic profiles of significant adverse events with crizotinib in Japanese patients with ABCB1 polymorphism. Cancer Sci 107:1117–1123.
-
(2016)
Cancer Sci
, vol.107
, pp. 1117-1123
-
-
Fujiwara, Y.1
Hamada, A.2
Mizugaki, H.3
Aikawa, H.4
Hata, T.5
Horinouchi, H.6
Kanda, S.7
Goto, Y.8
Itahashi, K.9
Nokihara, H.10
-
9
-
-
0037427972
-
The superfamily of organic anion transporting polypeptides
-
Hagenbuch B and Meier PJ (2003) The superfamily of organic anion transporting polypeptides. Biochim Biophys Acta 1609:1–18.
-
(2003)
Biochim Biophys Acta
, vol.1609
, pp. 1-18
-
-
Hagenbuch, B.1
Meier, P.J.2
-
10
-
-
1242272736
-
Organic anion transporting polypeptides of the Oatp/ slc21 family: Phylogenetic classification as oatp/ slco superfamily, new nomenclature and molecular/functional properties
-
Hagenbuch B and Meier PJ (2004) Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 447:653–665.
-
(2004)
Pflugers Arch
, vol.447
, pp. 653-665
-
-
Hagenbuch, B.1
Meier, P.J.2
-
11
-
-
0031751330
-
Ritonavir. Clinical pharmacokinetics and interactions with other anti-hiv agents
-
Hsu A, Granneman GR, and Bertz RJ (1998) Ritonavir. Clinical pharmacokinetics and interactions with other anti-HIV agents. Clin Pharmacokinet 35:275–291.
-
(1998)
Clin Pharmacokinet
, vol.35
, pp. 275-291
-
-
Hsu, A.1
Granneman, G.R.2
Bertz, R.J.3
-
12
-
-
0031723235
-
Prediction of pharmacokinetic alterations caused by drug-drug interactions: Metabolic interaction in the liver
-
Ito K, Iwatsubo T, Kanamitsu S, Ueda K, Suzuki H, and Sugiyama Y (1998) Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver. Pharmacol Rev 50:387–412.
-
(1998)
Pharmacol Rev
, vol.50
, pp. 387-412
-
-
Ito, K.1
Iwatsubo, T.2
Kanamitsu, S.3
Ueda, K.4
Suzuki, H.5
Sugiyama, Y.6
-
13
-
-
84921044413
-
Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1b1 inhibition profiles for the prediction of drug-drug interactions
-
Izumi S, Nozaki Y, Maeda K, Komori T, Takenaka O, Kusuhara H, and Sugiyama Y (2015) Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Drug Metab Dispos 43:235–247.
-
(2015)
Drug Metab Dispos
, vol.43
, pp. 235-247
-
-
Izumi, S.1
Nozaki, Y.2
Maeda, K.3
Komori, T.4
Takenaka, O.5
Kusuhara, H.6
Sugiyama, Y.7
-
14
-
-
0034145948
-
Gender-specific effects on verapamil pharmacokinetics and pharmacodynamics in humans
-
Krecic-Shepard ME, Barnas CR, Slimko J, Jones MP, and Schwartz JB (2000) Gender-specific effects on verapamil pharmacokinetics and pharmacodynamics in humans. J Clin Pharmacol 40:219–230.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 219-230
-
-
Krecic-Shepard, M.E.1
Barnas, C.R.2
Slimko, J.3
Jones, M.P.4
Schwartz, J.B.5
-
15
-
-
0346100571
-
Enterohepatic bile salt transporters in normal physiology and liver disease
-
Kullak-Ublick GA, Stieger B, and Meier PJ (2004) Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology 126:322–342.
-
(2004)
Gastroenterology
, vol.126
, pp. 322-342
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Meier, P.J.3
-
16
-
-
75149118366
-
Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid
-
Landersdorfer CB, Kirkpatrick CM, Kinzig M, Bulitta JB, Holzgrabe U, Jaehde U, Reiter A, Naber KG, Rodamer M, and Sörgel F (2010) Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid. Br J Clin Pharmacol 69:167–178.
-
(2010)
Br J Clin Pharmacol
, vol.69
, pp. 167-178
-
-
Landersdorfer, C.B.1
Kirkpatrick, C.M.2
Kinzig, M.3
Bulitta, J.B.4
Holzgrabe, U.5
Jaehde, U.6
Reiter, A.7
Naber, K.G.8
Rodamer, M.9
Sörgel, F.10
-
17
-
-
0020325272
-
Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans
-
Laskin OL, de Miranda P, King DH, Page DA, Longstreth JA, Rocco L, and Lietman PS (1982) Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans. Antimicrob Agents Chemother 21:804–807.
-
(1982)
Antimicrob Agents Chemother
, vol.21
, pp. 804-807
-
-
Laskin, O.L.1
De Miranda, P.2
King, D.H.3
Page, D.A.4
Longstreth, J.A.5
Rocco, L.6
Lietman, P.S.7
-
18
-
-
33846571368
-
Effect of oatp1b transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers
-
Lau YY, Huang Y, Frassetto L, and Benet LZ (2007) effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers. Clin Pharmacol Ther 81:194–204.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 194-204
-
-
Lau, Y.Y.1
Huang, Y.2
Frassetto, L.3
Benet, L.Z.4
-
19
-
-
84876748933
-
Functional cooperation of smcts and urat1 for renal reabsorption transport of urate
-
Lu Y, Nakanishi T, and Tamai I (2013) Functional cooperation of SMCTs and URAT1 for renal reabsorption transport of urate. Drug Metab Pharmacokinet 28:153–158.
-
(2013)
Drug Metab Pharmacokinet
, vol.28
, pp. 153-158
-
-
Lu, Y.1
Nakanishi, T.2
Tamai, I.3
-
22
-
-
16544374913
-
The organic anion transporter (oatp) family
-
Mikkaichi T, Suzuki T, Tanemoto M, Ito S, and Abe T (2004a) The organic anion transporter (OATP) family. Drug Metab Pharmacokinet 19:171–179.
-
(2004)
Drug Metab Pharmacokinet
, vol.19
, pp. 171-179
-
-
Mikkaichi, T.1
Suzuki, T.2
Tanemoto, M.3
Ito, S.4
Abe, T.5
-
23
-
-
12144288563
-
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney
-
Mikkaichi T, Suzuki T, Onogawa T, Tanemoto M, Mizutamari H, Okada M, Chaki T, Masuda S, Tokui T, Eto N, et al. (2004b) Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci USA 101:3569–3574.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3569-3574
-
-
Mikkaichi, T.1
Suzuki, T.2
Onogawa, T.3
Tanemoto, M.4
Mizutamari, H.5
Okada, M.6
Chaki, T.7
Masuda, S.8
Tokui, T.9
Eto, N.10
-
24
-
-
84885951869
-
Oxidative albumin damage in chronic liver failure: Relation to albumin binding capacity, liver dysfunction and survival
-
Oettl K, Birner-Gruenberger R, Spindelboeck W, Stueger HP, Dorn L, Stadlbauer V, Putz-Bankuti C, Krisper P, Graziadei I, Vogel W, et al. (2013) Oxidative albumin damage in chronic liver failure: relation to albumin binding capacity, liver dysfunction and survival. J Hepatol 59:978–983.
-
(2013)
J Hepatol
, vol.59
, pp. 978-983
-
-
Oettl, K.1
Birner-Gruenberger, R.2
Spindelboeck, W.3
Stueger, H.P.4
Dorn, L.5
Stadlbauer, V.6
Putz-Bankuti, C.7
Krisper, P.8
Graziadei, I.9
Vogel, W.10
-
25
-
-
0031709406
-
Pharmacokinetic interaction between ritonavir and clarithromycin
-
Ouellet D, Hsu A, Granneman GR, Carlson G, Cavanaugh J, Guenther H, and Leonard JM (1998) Pharmacokinetic interaction between ritonavir and clarithromycin. Clin Pharmacol Ther 64:355–362.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 355-362
-
-
Ouellet, D.1
Hsu, A.2
Granneman, G.R.3
Carlson, G.4
Cavanaugh, J.5
Guenther, H.6
Leonard, J.M.7
-
27
-
-
84884234269
-
Interaction of ethambutol with human organic cation transporters of the slc22 family indicates potential for drug-drug interactions during antituberculosis therapy
-
Pan X, Wang L, Gründemann D, and Sweet DH (2013) Interaction of Ethambutol with human organic cation transporters of the SLC22 family indicates potential for drug-drug interactions during antituberculosis therapy. Antimicrob Agents Chemother 57:5053–5059.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 5053-5059
-
-
Pan, X.1
Wang, L.2
Gründemann, D.3
Sweet, D.H.4
-
28
-
-
84994881388
-
Inhibitory interaction potential of 22 antituberculosis drugs on organic anion and cation transporters of the slc22a family
-
Parvez MM, Kaisar N, Shin HJ, Jung JA, and Shin JG (2016) Inhibitory interaction potential of 22 antituberculosis drugs on organic anion and cation transporters of the SLC22A family. Antimicrob Agents Chemother 60:6558–6567.
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 6558-6567
-
-
Parvez, M.M.1
Kaisar, N.2
Shin, H.J.3
Jung, J.A.4
Shin, J.G.5
-
29
-
-
0032737529
-
Clinical pharmacokinetics of clarithromycin
-
Rodvold KA (1999) Clinical pharmacokinetics of clarithromycin. Clin Pharmacokinet 37:385–398.
-
(1999)
Clin Pharmacokinet
, vol.37
, pp. 385-398
-
-
Rodvold, K.A.1
-
30
-
-
0034797589
-
Pharmacokinetics and pharmacodynamics of fluoroquinolones
-
Rodvold KA and Neuhauser M (2001) Pharmacokinetics and pharmacodynamics of fluoroquinolones. Pharmacotherapy 21:233S–252S.
-
(2001)
Pharmacotherapy
, vol.21
, pp. 233S-252S
-
-
Rodvold, K.A.1
Neuhauser, M.2
-
31
-
-
84937395433
-
Organic anion transporting polypeptides 1b1 and 1b3 play an important role in uremic toxin handling and drug-uremic toxin interactions in the liver
-
Sato T, Yamaguchi H, Kogawa T, Abe T, and Mano N (2014) Organic anion transporting polypeptides 1B1 and 1B3 play an important role in uremic toxin handling and drug-uremic toxin interactions in the liver. J Pharm Pharm Sci 17:475–484.
-
(2014)
J Pharm Pharm Sci
, vol.17
, pp. 475-484
-
-
Sato, T.1
Yamaguchi, H.2
Kogawa, T.3
Abe, T.4
Mano, N.5
-
32
-
-
85010703157
-
Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (oatp)1b1, oatp1b3 and oatp2b1: Gefitinib shows contradictory interaction with oatp1b3
-
published ahead of print
-
Sato T, Ito H, Hirata A, Abe T, Mano N, and Yamaguchi H (2017) Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3. Xenobiotica DOI: 10.1080/00498254.2016.1275880 [published ahead of print].
-
(2017)
Xenobiotica
-
-
Sato, T.1
Ito, H.2
Hirata, A.3
Abe, T.4
Mano, N.5
Yamaguchi, H.6
-
33
-
-
77949452205
-
Effect of saquinavir/ ritonavir on p-glycoprotein activity in healthy volunteers using digoxin as a probe
-
Schmitt C, Kaeser B, Riek M, Bech N, and Kreuzer C (2010) Effect of saquinavir/ ritonavir on P-glycoprotein activity in healthy volunteers using digoxin as a probe. Int J Clin Pharmacol Ther 48:192–199.
-
(2010)
Int J Clin Pharmacol Ther
, vol.48
, pp. 192-199
-
-
Schmitt, C.1
Kaeser, B.2
Riek, M.3
Bech, N.4
Kreuzer, C.5
-
34
-
-
85021859530
-
Delineating the role of various factors in renal disposition of digoxin through application of physiologically based kidney model to renal impairment populations
-
Scotcher D, Jones CR, Galetin A, and Rostami-Hodjegan A (2017) Delineating the role of various factors in renal disposition of digoxin through application of physiologically based kidney model to renal impairment populations. J Pharmacol Exp Ther 360:484–495.
-
(2017)
J Pharmacol Exp Ther
, vol.360
, pp. 484-495
-
-
Scotcher, D.1
Jones, C.R.2
Galetin, A.3
Rostami-Hodjegan, A.4
-
35
-
-
0035023185
-
Clinical pharmacokinetics of fluvastatin
-
Scripture CD and Pieper JA (2001) Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet 40:263–281.
-
(2001)
Clin Pharmacokinet
, vol.40
, pp. 263-281
-
-
Scripture, C.D.1
Pieper, J.A.2
-
36
-
-
85009918033
-
Preference of conjugated bile acids over unconjugated bile acids as substrates for oatp1b1 and Oatp1b3
-
Suga T, Yamaguchi H, Sato T, Maekawa M, Goto J, and Mano N (2017) Preference of conjugated bile acids over unconjugated bile acids as substrates for OATP1B1 and OATP1B3. PLoS One 12:e0169719.
-
(2017)
Plos One
, vol.12
-
-
Suga, T.1
Yamaguchi, H.2
Sato, T.3
Maekawa, M.4
Goto, J.5
Mano, N.6
-
37
-
-
72049086464
-
Slco4c1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation
-
Toyohara T, Suzuki T, Morimoto R, Akiyama Y, Souma T, Shiwaku HO, Takeuchi Y, Mishima E, Abe M, Tanemoto M, et al. (2009) SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. J Am Soc Nephrol 20:2546–2555.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 2546-2555
-
-
Toyohara, T.1
Suzuki, T.2
Morimoto, R.3
Akiyama, Y.4
Souma, T.5
Shiwaku, H.O.6
Takeuchi, Y.7
Mishima, E.8
Abe, M.9
Tanemoto, M.10
-
38
-
-
84959018708
-
Evaluation of ketoconazole and its alternative clinical Cyp3a4/5 inhibitors as inhibitors of drug transporters: The in vitro effects of ketoconazole, ritonavir, clarithromycin, and itraconazole on 13 clinically-relevant drug transporters
-
Vermeer LM, Isringhausen CD, Ogilvie BW, and Buckley DB (2016) Evaluation of ketoconazole and its alternative clinical CYP3A4/5 inhibitors as inhibitors of drug transporters: the in vitro effects of ketoconazole, ritonavir, clarithromycin, and itraconazole on 13 clinically-relevant drug transporters. Drug Metab Dispos 44: 453–459.
-
(2016)
Drug Metab Dispos
, vol.44
, pp. 453-459
-
-
Vermeer, L.M.1
Isringhausen, C.D.2
Ogilvie, B.W.3
Buckley, D.B.4
-
39
-
-
0024335075
-
Plasma protein binding of frusemide in liver disease: Effect of hypoalbuminaemia and hyperbilirubinaemia
-
Viani A, Carrai M, and Pacifici GM (1989) Plasma protein binding of frusemide in liver disease: effect of hypoalbuminaemia and hyperbilirubinaemia. Br J Clin Pharmacol 28:175–178.
-
(1989)
Br J Clin Pharmacol
, vol.28
, pp. 175-178
-
-
Viani, A.1
Carrai, M.2
Pacifici, G.M.3
-
41
-
-
77954289040
-
Transport of estrone 3-sulfate mediated by organic anion transporter oatp4c1: Estrone 3-sulfate binds to the different recognition site for digoxin in oatp4c1
-
Yamaguchi H, Sugie M, Okada M, Mikkaichi T, Toyohara T, Abe T, Goto J, Hishinuma T, Shimada M, and Mano N (2010) Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1. Drug Metab Pharmacokinet 25:314–317.
-
(2010)
Drug Metab Pharmacokinet
, vol.25
, pp. 314-317
-
-
Yamaguchi, H.1
Sugie, M.2
Okada, M.3
Mikkaichi, T.4
Toyohara, T.5
Abe, T.6
Goto, J.7
Hishinuma, T.8
Shimada, M.9
Mano, N.10
-
42
-
-
69449099763
-
Organic anion transporting polypeptide (oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of oatp1a1 in renal elimination of perfluorocarboxylates in rats
-
Yang CH, Glover KP, and Han X (2009) Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats. Toxicol Lett 190:163–171.
-
(2009)
Toxicol Lett
, vol.190
, pp. 163-171
-
-
Yang, C.H.1
Glover, K.P.2
Han, X.3
-
43
-
-
79551489546
-
Organic cation transporter Oct/slc22a and h(1)/ organic cation antiporter mate/slc47a are key molecules for nephrotoxicity of platinum agents
-
Yonezawa A and Inui K (2011) Organic cation transporter OCT/SLC22A and H(1)/ organic cation antiporter MATE/SLC47A are key molecules for nephrotoxicity of platinum agents. Biochem Pharmacol 81:563–568.
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 563-568
-
-
Yonezawa, A.1
Inui, K.2
|