Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain

NeuroMolecular Medicine

Volumn 19, Issue 2-3, 2017, Pages 375-386

  Zhang, Cheng Wu ^a,f   Tai, Yee Kit ^b   Chai, Bing Han ^a   Chew, Katherine C M ^b   Ang, Eng Tat ^b   Tsang, Fai ^b   Tan, Bryce W Q ^b   Hong, Eugenia T E ^a   Asad, Abu Bakar Ali ^c   Chuang, Kai Hsiang ^c   Lim, Kah Leong ^a,b,d,e   Soong, Tuck Wah ^a,b,e  

^a NATIONAL NEUROSCIENCE INSTITUTE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c AGENCY FOR SCIENCE   (Singapore)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f NANJING TECH UNIVERSITY   (China)

Author keywords

6 OHDA; Dopamine; Oxidative stress; Parkin; Parkinson s disease

Indexed keywords

IRON; MANGANESE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; OXIDOPAMINE; PARKIN; CATION TRANSPORT PROTEIN; RECOMBINANT PROTEIN; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IRON STORAGE; KNOCKOUT MOUSE; MOUSE; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROTAROD TEST; SUBSTANTIA NIGRA; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMICALLY INDUCED; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; MACACA FASCICULARIS; METABOLISM; PARKINSONISM; PHYSIOLOGY; PRION; PROMOTER REGION;

ANIMALS; CATION TRANSPORT PROTEINS; GENE EXPRESSION REGULATION; IRON; MACACA FASCICULARIS; MANGANESE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDOPAMINE; PARKINSONIAN DISORDERS; PRIONS; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS; ROTAROD PERFORMANCE TEST; SUBSTANTIA NIGRA; UBIQUITIN-PROTEIN LIGASES;

EID: 85022229654     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-017-8451-0     Document Type: Article

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