Cell-cycle dynamics of chromosomal organization at single-cell resolution

Nature

Volumn 547, Issue 7661, 2017, Pages 61-67

  Nagano, Takashi ^a   Lubling, Yaniv ^b   Várnai, Csilla ^a   Dudley, Carmel ^b   Leung, Wing ^a   Baran, Yael ^b   Mendelson Cohen, Netta ^b   Wingett, Steven ^a   Fraser, Peter ^a,c   Tanay, Amos ^b  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c FLORIDA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS AND CELL COMPONENTS; CHROMOSOME; CYTOLOGY; DNA; GENOME; GENOMICS; METAZOAN; THREE-DIMENSIONAL MODELING;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL SELECTION; CHROMOSOME STRUCTURE; COMPUTER MODEL; DIPLOIDY; DNA REPLICATION; EMBRYO; EPIGENETICS; FLOW CYTOMETRY; HAPLOIDY; MOUSE; MOUSE EMBRYONIC STEM CELL; NONHUMAN; PRIORITY JOURNAL; SINGLE CELL ANALYSIS; ANIMAL; CELL COMPARTMENTALIZATION; CHEMISTRY; CHROMOSOME; CYTOLOGY; GENETIC EPIGENESIS; GENETICS; METABOLISM; PHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; THREE DIMENSIONAL IMAGING;

METAZOA;

ANIMALS; CELL COMPARTMENTATION; CELL CYCLE; CHROMOSOMES, MAMMALIAN; EPIGENESIS, GENETIC; HAPLOIDY; IMAGING, THREE-DIMENSIONAL; MICE; MOUSE EMBRYONIC STEM CELLS; REPRODUCIBILITY OF RESULTS; SINGLE-CELL ANALYSIS;

EID: 85022195504     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature23001     Document Type: Article

References (22)

1. Paweletz, N. Walther Flemming: pioneer of mitosis research. Nat. Rev. Mol. Cell Biol. 2, 72-75 (2001).
2. Lieberman-Aiden, E. et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 326, 289-293 (2009).
3. Sexton, T. et al. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 148, 458-472 (2012).
4. Nora, E. P. et al. Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature 485, 381-385 (2012).
5. Dixon, J. R. et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 485, 376-380 (2012).
6. Sofueva, S. et al. Cohesin-mediated interactions organize chromosomal domain architecture. EMBO J. 32, 3119-3129 (2013).
7. Rao, S. S. P. S. P. et al. A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell 159, 1665-1680 (2014).
8. Zuin, J. et al. Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells. Proc. Natl Acad. Sci. USA 111, 996-1001 (2014).
9. de Wit, E. et al. CTCF binding polarity determines chromatin looping. Mol. Cell 60, 676-684 (2015).
10. Flavahan, W. A. et al. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature 529, 110-114 (2016).
11. Naumova, N. et al. Organization of the mitotic chromosome. Science 342, 948-953 (2013).
12. Nagano, T. et al. Single-cell Hi-C reveals cell-to-cell variability in chromosome structure. Nature 502, 59-64 (2013).
13. Nagano, T. et al. Comparison of Hi-C results using in-solution versus in-nucleus ligation. Genome Biol. 16, 175 (2015).
14. Pope, B. D. et al. Topologically associating domains are stable units of replication-timing regulation. Nature 515, 402-405 (2014).
15. Mouse ENCODE Consortium et al. An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol. 13, 418 (2012).
16. Boettiger, A. N. et al. Super-resolution imaging reveals distinct chromatin folding for different epigenetic states. Nature 529, 418-422 (2016).
17. Peric-Hupkes, D. et al. Molecular maps of the reorganization of genomenuclear lamina interactions during differentiation. Mol. Cell 38, 603-613 (2010).
18. Dileep, V. et al. Topologically associating domains and their long-range contacts are established during early G1 coincident with the establishment of the replication-timing program. Genome Res. 25, 1104-1113 (2015).
19. Britton-Davidian, J., Cazaux, B. & Catalan, J. Chromosomal dynamics of nucleolar organizer regions (NORs) in the house mouse: micro-evolutionary insights. Heredity 108, 68-74 (2012).
20. Ramani, V. et al. Massively multiplex single-cell Hi-C. Nat. Methods 14, 263-266 (2017).
21. Stevens, T. J. et al. 3D structures of individual mammalian genomes studied by single-cell Hi-C. Nature 544, 59-64 (2017).
22. Flyamer, I. M. et al. Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition. Nature 544, 110-114 (2017).