Immunological characterization of latent tuberculosis infection in a low endemic country

Tuberculosis

Volumn 106, Issue , 2017, Pages 62-72

  de Paus, Roelof A ^a   van Meijgaarden, Krista E ^a   Prins, Corine ^a   Kamphorst, Margreet H ^b   Arend, Sandra M ^a   Ottenhoff, Tom H M ^a   Joosten, Simone A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GGD Hollands Midden   (Netherlands)

Author keywords

Latent tuberculosis infection; Lymphocyte stimulation; Quantiferon; Tuberculin skin test; Tuberculosis

Indexed keywords

BACTERIAL ANTIGEN; MYCOBACTERIUM TUBERCULOSIS ANTIGEN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CFP-10 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; GAMMA INTERFERON; IFNG PROTEIN, HUMAN; TUBERCULIN;

ADULT; ANTIGEN RECOGNITION; ARTICLE; FOLLOW UP; HUMAN; IMMIGRANT; IMMUNITY; LATENT TUBERCULOSIS; LYMPHOCYTE TRANSFORMATION TEST; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS TEST KIT; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TUBERCULIN TEST; ADOLESCENT; CELL CULTURE; CELLULAR IMMUNITY; COMPARATIVE STUDY; ENDEMIC DISEASE; FEMALE; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INTERFERON GAMMA RELEASE ASSAY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NETHERLANDS; PREDICTIVE VALUE; REPRODUCIBILITY; YOUNG ADULT;

ADOLESCENT; ADULT; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELLS, CULTURED; ENDEMIC DISEASES; FEMALE; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, CELLULAR; INTERFERON-GAMMA; INTERFERON-GAMMA RELEASE TESTS; LATENT TUBERCULOSIS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; NETHERLANDS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; TUBERCULIN; TUBERCULIN TEST; YOUNG ADULT;

EID: 85021896845     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2017.07.001     Document Type: Article

References (37)

1. Lonnroth, K., Migliori, G.B., Abubakar, I., D'Ambrosio, L., de Vries, G., Diel, R., et al. Towards tuberculosis elimination: an action framework for low-incidence countries. Eur Respir J 45 (2015), 928–952.
2. Erkens, C.G., Slump, E., Verhagen, M., Schimmel, H., de Vries, G., Cobelens, F., et al. Monitoring latent tuberculosis infection diagnosis and management in The Netherlands. Eur Respir J 47 (2016), 1492–1501.
3. Erkens, C.G., Kamphorst, M., Abubakar, I., Bothamley, G.H., Chemtob, D., Haas, W., et al. Tuberculosis contact investigation in low prevalence countries: a European consensus. Eur Respir J 36 (2010), 925–949.
4. Erkens, C.G., Dinmohamed, A.G., Kamphorst, M., Toumanian, S., van Nispen-Dobrescu, R., Alink, M., et al. Added value of interferon-gamma release assays in screening for tuberculous infection in The Netherlands. Int J Tuberc Lung Dis Off. J Int Union Against Tuberc Lung Dis 18 (2014), 413–420.
5. Pai, M., Denkinger, C.M., Kik, S.V., Rangaka, M.X., Zwerling, A., Oxlade, O., et al. Gamma interferon release assays for detection of Mycobacterium tuberculosis infection. Clin Microbiol Rev 27 (2014), 3–20.
6. Goletti, D., Sanduzzi, A., Delogu, G., Performance of the tuberculin skin test and interferon-gamma release assays: an update on the accuracy, cutoff stratification, and new potential immune-based approaches. J Rheumatol. Suppl 91 (2014), 24–31.
7. Trajman, A., Steffen, R.E., Menzies, D., Interferon-Gamma release assays versus tuberculin skin testing for the diagnosis of latent tuberculosis infection: an overview of the evidence. Pulm Med, 2013, 2013, 601737.
8. Adams, L.V., Waddell, R.D., Von Reyn, C.F., T-SPOT.TB Test(R) results in adults with Mycobacterium avium complex pulmonary disease. Scand J Infect Dis 40 (2008), 196–203.
9. Zwerling, A., Behr, M.A., Verma, A., Brewer, T.F., Menzies, D., Pai, M., The BCG World Atlas: a database of global BCG vaccination policies and practices. PLoS Med, 8, 2011, e1001012.
10. Lin, M.Y., Reddy, T.B., Arend, S.M., Friggen, A.H., Franken, K.L., van Meijgaarden, K.E., et al. Cross-reactive immunity to Mycobacterium tuberculosis DosR regulon-encoded antigens in individuals infected with environmental, nontuberculous mycobacteria. Infect Immun 77 (2009), 5071–5079.
11. Commandeur, S., Lin, M.Y., van Meijgaarden, K.E., Friggen, A.H., Franken, K.L., Drijfhout, J.W., et al. Double- and monofunctional CD4(+) and CD8(+) T-cell responses to Mycobacterium tuberculosis DosR antigens and peptides in long-term latently infected individuals. Eur J Immunol 41 (2011), 2925–2936.
12. Pai, M., Zwerling, A., Menzies, D., Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update. Ann Intern Med 149 (2008), 177–184.
13. Banaei, N., Gaur, R.L., Pai, M., Interferon gamma release assays for latent tuberculosis: what are the sources of variability?. J Clin Microbiol 54 (2016), 845–850.
14. Tagmouti, S., Slater, M., Benedetti, A., Kik, S.V., Banaei, N., Cattamanchi, A., et al. Reproducibility of interferon gamma (IFN-gamma) release Assays. A systematic review. Ann Am Thorac Soc 11 (2014), 1267–1276.
15. Menzies, D., Interpretation of repeated tuberculin tests. Boosting, conversion, and reversion. Am J Respir Crit Care Med 159 (1999), 15–21.
16. Pai, M., Elwood, K., Interferon-gamma release assays for screening of health care workers in low tuberculosis incidence settings: dynamic patterns and interpretational challenges. Can Respir J 19 (2012), 81–83.
17. Zwerling, A., van den Hof, S., Scholten, J., Cobelens, F., Menzies, D., Pai, M., Interferon-gamma release assays for tuberculosis screening of healthcare workers: a systematic review. Thorax 67 (2012), 62–70.
18. Franken, W.P., Arend, S.M., Thijsen, S.F., Bouwman, J.J., Koster, B.F., van Dissel, J.T., et al. Interferon-gamma release assays during follow-up of tuberculin skin test-positive contacts. Int J Tuberc Lung Dis Off. J Int Union Against Tuberc Lung Dis 12 (2008), 1286–1294.
19. Franken, W.P., Koster, B.F., Bossink, A.W., Thijsen, S.F., Bouwman, J.J., van Dissel, J.T., et al. Follow-up study of tuberculosis-exposed supermarket customers with negative tuberculin skin test results in association with positive gamma interferon release assay results. Clin Vacc. Immunol CVI 14 (2007), 1239–1241.
20. Bartalesi, F., Goletti, D., Spinicci, M., Cavallo, A., Attala, L., Mencarini, J., et al. Serial QuantiFERON TB-gold in-tube testing during LTBI therapy in candidates for TNFi treatment. J Infect 66 (2013), 346–356.
21. Boer, M.C., Joosten, S.A., Ottenhoff, T.H., Regulatory T-cells at the interface between human host and pathogens in infectious diseases and vaccination. Front Immunol, 6, 2015, 217.
22. Leyten, E.M., Arend, S.M., Prins, C., Cobelens, F.G., Ottenhoff, T.H., van Dissel, J.T., Discrepancy between Mycobacterium tuberculosis-specific gamma interferon release assays using short and prolonged in vitro incubation. Clin Vacc. Immunol CVI 14 (2007), 880–885.
23. Butera, O., Chiacchio, T., Carrara, S., Casetti, R., Vanini, V., Meraviglia, S., et al. New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term response. BMC Infect Dis, 9, 2009, 182.
24. Delogu, G., Chiacchio, T., Vanini, V., Butera, O., Cuzzi, G., Bua, A., et al. Methylated HBHA produced in M. smegmatis discriminates between active and non-active tuberculosis disease among RD1-responders. PloS One, 6, 2011, e18315.
25. Hill, P.C., Jackson-Sillah, D., Fox, A., Franken, K.L., Lugos, M.D., Jeffries, D.J., et al. ESAT-6/CFP-10 fusion protein and peptides for optimal diagnosis of mycobacterium tuberculosis infection by ex vivo enzyme-linked immunospot assay in the Gambia. J Clin Microbiol 43 (2005), 2070–2074.
26. Abramo, C., Meijgaarden, K.E., Garcia, D., Franken, K.L., Klein, M.R., Kolk, A.J., et al. Monokine induced by interferon gamma and IFN-gamma response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients. Microbes Infect/Institut Pasteur 8 (2006), 45–51.
27. Erkens, C.G.M., Slump, E., Verhagen, M., Schimmel, H., Cobelens, F., van den Hof, S., Risk of developing tuberculosis disease among persons diagnosed with latent tuberculosis infection in The Netherlands. Eur Respir J 48 (2016), 1420–1428.
28. Menzies, D., Gardiner, G., Farhat, M., Greenaway, C., Pai, M., Thinking in three dimensions: a web-based algorithm to aid the interpretation of tuberculin skin test results. Int J Tuberc Lung Dis Off. J Int Union Against Tuberc Lung Dis 12 (2008), 498–505.
29. Rozot, V., Patrizia, A., Vigano, S., Mazza-Stalder, J., Idrizi, E., Day, C.L., et al. Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis. Clin Infect Dis Off. Publ Infect Dis Soc Am 60 (2015), 432–437.
30. Petruccioli, E., Chiacchio, T., Pepponi, I., Vanini, V., Urso, R., Cuzzi, G., et al. First characterization of the CD4 and CD8 T-cell responses to QuantiFERON-TB plus. J Infect 73:6 (2016), 588–597.
31. Metcalfe, J.Z., Cattamanchi, A., McCulloch, C.E., Lew, J.D., Ha, N.P., Graviss, E.A., Test variability of the QuantiFERON-TB gold in-tube assay in clinical practice. Am J Respir Crit Care Med 187 (2013), 206–211.
32. Andrews, J.R., Nemes, E., Tameris, M., Landry, B.S., Mahomed, H., McClain, J.B., et al. Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study. Lancet Respir Med 5:4 (2017), 282–290.
33. Mulder, C., van Deutekom, H., Huisman, E.M., Toumanian, S., Koster, B.F., Meijer-Veldman, W., et al. Role of the QuantiFERON(R)-TB Gold In-Tube assay in screening new immigrants for tuberculosis infection. Eur Respir J 40 (2012), 1443–1449.
34. Zellweger, J.P., Sotgiu, G., Block, M., Dore, S., Altet, N., Blunschi, R., et al. Risk assessment of tuberculosis in contacts by IFN-gamma release assays. A tuberculosis network european trials group study. Am J Respir Crit Care Med 191 (2015), 1176–1184.
35. Petruccioli, E., Scriba, T.J., Petrone, L., Hatherill, M., Cirillo, D.M., Joosten, S.A., et al. Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis. Eur Respir J 48 (2016), 1751–1763.
36. Sloot, R., Schim van der Loeff, M.F., van Zwet, E.W., Haks, M.C., Keizer, S.T., Scholing, M., et al. Biomarkers can identify pulmonary tuberculosis in HIV-infected drug users months prior to clinical diagnosis. EBioMedicine 2 (2015), 172–179.
37. Zak, D.E., Penn-Nicholson, A., Scriba, T.J., Thompson, E., Suliman, S., Amon, L.M., et al. A blood RNA signature for tuberculosis disease risk: a prospective cohort study. Lancet 387 (2016), 2312–2322.