New tools for detecting latent tuberculosis infection: Evaluation of RD1-specific long-term response

BMC Infectious Diseases

Volumn 9, Issue , 2009, Pages

  Butera, Ornella ^a   Chiacchio, Teresa ^a   Carrara, Stefania ^a   Casetti, Rita ^b   Vanini, Valentina ^a   Meraviglia, Serena ^c   Guggino, Giuliana ^c   Dieli, Francesco ^c   Vecchi, Marco ^d   Lauria, Francesco N ^d   Marruchella, Almerico ^d   Laurenti, Patrizia ^e   Singh, Mahavir ^f   Caccamo, Nadia ^c   Girardi, Enrico ^g   Goletti, Delia ^a  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^b Cellular Immunology Laboratory (INMI)   (Italy)

^c UNIVERSITY OF PALERMO   (Italy)

^d Health Department (INMI)   (Italy)

^e CATHOLIC UNIVERSITY   (Italy)

^f LIONEX DIAGNOSTICS AND THERAPEUTICS GMBH   (Germany)

^g Department of Epidemiology and Preclinical Research ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BCG VACCINE; GAMMA INTERFERON; RDI ANTIGEN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BCG VACCINATION; CLINICAL TRIAL; CONTROLLED STUDY; CULTURE MEDIUM; DIAGNOSTIC VALUE; FEMALE; HUMAN; IMMUNOASSAY; IMMUNOSTIMULATION; INFECTION; LATENT TUBERCULOSIS INFECTION; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MICROBIOLOGY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SHORT COURSE THERAPY; SMEAR; TREATMENT RESPONSE; TUBERCULIN TEST; TUBERCULOSIS; ANALYTICAL EQUIPMENT; BLOOD; IMMUNOLOGY; ISOLATION AND PURIFICATION; LATENT TUBERCULOSIS; METHODOLOGY; MIDDLE AGED;

ADULT; ANTIGENS, BACTERIAL; FEMALE; HUMANS; INTERFERON-GAMMA; LATENT TUBERCULOSIS; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; REAGENT KITS, DIAGNOSTIC; TUBERCULIN TEST; YOUNG ADULT;

EID: 71049177888     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-9-182     Document Type: Article

References (30)

1. Pai M, Zwerling A, Menzies D. Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: An update. Ann Intern Med 2008, 149:177-84. 18593687.
2. Goletti D, Carrara S, Butera O, Amicosante M, Ernst M, Sauzullo I, Vullo V, Cirillo D, Borroni E, Markova R, Drenska R, Dominguez J, Latorre I, Angeletti C, Navarra A, Petrosillo N, Lauria FN, Ippolito G, Migliori GB, Lange C, Girardi E. Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study. PLoS ONE 2008, 3:e3417. 10.1371/journal.pone.0003417, 2561073, 18923709.
3. Arend SM, Andersen P, van Meijgaarden KE, Skjot RL, Subronto YW, van Dissel JT, Ottenhoff TH. Detection of active tuberculosis infection by T cell responses to early-secreted antigenic target 6-kDa protein and culture filtrate protein 10. J Infect Dis 2000, 181:1850-1854. 10.1086/315448, 10823800.
4. Munk ME, Arend SM, Brock I, Ottenhoff TH, Andersen P. Use of ESAT-6 and CFP-10 antigens for diagnosis of extrapulmonary tuberculosis. J Infect Dis 2001, 183:175-176. 10.1086/317663, 11106545.
5. Ravn P, Demissie A, Eguale T, Wondwosson H, Lein D, Amoudy HA, Mustafa AS, Jensen AK, Holm A, Rosenkrands I, Oftung F, Olobo J, von Reyn F, Andersen P. Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis. J Infect Dis 1999, 179:637-645. 10.1086/314640, 9952370.
6. Wu-Hsieh BA, Chen CK, Chang JH, Lai SY, Wu CH, Cheng WC, Andersen P, Doherty TM. Long-lived immune response to early secretory antigenic target 6 in individuals who had recovered from tuberculosis. Clin Infect Dis 2001, 33:1336-1340. 10.1086/323044, 11565073.
7. Mahairas GG, Sabo PJ, Hickey MJ, Singh DC, Stover CK. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J Bacteriol 1996, 178:1274-82. 177799, 8631702.
8. Ewer K, Deeks J, Alvarez L, Bryant G, Waller S, Andersen P, Monk P, Lalvani A. Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet 2003, 361:1168-1173. 10.1016/S0140-6736(03)12950-9, 12686038.
9. Lalvani A, Pathan AA, Durkan H, Wilkinson KA, Whelan A, Deeks JJ, Reece WH, Latif M, Pasvol G, Hill AV. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Lancet 2001, 357:2017-2021. 10.1016/S0140-6736(00)05115-1, 11438135.
10. Shams H, Weis SE, Klucar P, Lalvani A, Moonan PK, Pogoda JM, Ewer K, Barnes PF. Enzyme-linked immunospot and tuberculin skin testing to detect latent tuberculosis infection. Am J Respir Crit Care Med 2005, 172:1161-1168. 10.1164/rccm.200505-748OC, 2718400, 16081545.
11. Leyten EM, Arend SM, Prins C, Cobelens FG, Ottenhoff TH, van Dissel JT. Discrepancy between Mycobacterium tuberculosis-specific gamma interferon release assays using short and prolonged in vitro incubation. Clin Vaccine Immunol 2007, 14:880-5. 10.1128/CVI.00132-07, 1951056, 17507543.
12. Arend SM, Thijsen SF, Leyten EM, Bouwman JJ, Franken WP, Koster BF, Cobelens FG, van Houte AJ, Bossink AW. Comparison of two interferon-gamma assays and tuberculin skin test for tracing TB contacts. Am J Respir Crit Care Med 2007, 175:618-627. 10.1164/rccm.200608-1099OC, 17170386.
13. Leyten EM, Prins C, Bossink AW, Thijsen S, Ottenhoff TH, van Dissel JT, Arend SM. Effect of tuberculin skin testing on a Mycobacterium tuberculosis-specific IFN-γ assay. Eur Respir J 2007, 29:1212-6. 10.1183/09031936.00117506, 17215314.
14. Black GF, Dockrell HM, Crampin AC, Floyd S, Weir RE, Bliss L, Sichali L, Mwaungulu L, Kanyongoloka H, Ngwira B, Warndorff DK, Fine PE. Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi. J Infect Dis 2001, 1(184):322-9.
15. American Thoracic Society Diagnostic standards and classification of tuberculosis in adults and children. Am J Respir Crit Care Med 2000, 161:1376-95.
16. McAdam JM, Bucher SJ, Brickner PW, Vincent RL, Lascher S. Latent tuberculosis and active tuberculosis disease rates among the homeless. Emerg Infect Dis 2009, 15:1109-11. 10.3201/eid1507.080410, 2744228, 19624932.
17. Lawn SD, Bangani N, Vogt M, Bekker LG, Badri M, Ntobongwana M, Dockrell HM, Wilkinson RJ, Wood R. Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa. BMC Infect Dis 2007, 7:99. 10.1186/1471-2334-7-99, 2031899, 17725839.
18. Mori T, Sakatani M, Yamagishi F, Takashima T, Kawabe Y, Nagao K, Shigeto E, Harada N, Mitarai S, Okada M, Suzuki K, Inoue Y, Tsuyuguchi K, Sasaki Y, Mazurek GH, Tsuyuguchi I. Specific detection of tuberculosis infection: an interferon-gamma-based assay using new antigens. Am J Respir Crit Care Med 2004, 170:59-64. 10.1164/rccm.200402-179OC, 15059788.
19. Goletti D, Parracino MP, Butera O, Bizzoni F, Casetti R, Dainotto D, Anzidei G, Nisii C, Ippolito G, Poccia F, Girardi E. I.soniazid prophylaxis differently modulates T-cell responses to RD1-epitopes in contacts recently exposed to Mycobacterium tuberculosis a pilot study. Respir Res 2007, 8:5. 10.1186/1465-9921-8-5, 1794408, 17257436.
20. Goletti D, Carrara S, Vincenti D, Saltini C, Rizzi EB, Schininà V, Ippolito G, Amicosante M, Girardi E. Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study. Clin Microbiol Infect 2006, 12:544-50. 10.1111/j.1469-0691.2006.01391.x, 16700703.
21. Aiken AM, Hill PC, Fox A, McAdam KP, Jackson-Sillah D, Lugos MD, Donkor SA, Adegbola RA, Brookes RH. Reversion of the ELISPOT test after treatment in Gambian tuberculosis cases. BMC Infect Dis 2006, 30:6-66.
22. Carrara S, Vincenti D, Petrosillo N, Amicosante M, Girardi E, Goletti D. Use of a T cell-based assay for monitoring efficacy of antituberculosis therapy. Clin Infect Dis 2004, 38:754-6. 10.1086/381754, 14986262.
23. Sauzullo I, Mengoni F, Lichtner M, Massetti AP, Rossi R, Iannetta M, Marocco R, Del Borgo C, Soscia F, Vullo V, Mastroianni CM. In vivo and in vitro effects of antituberculosis treatment on mycobacterial Interferon-gamma T cell response. PLoS One 2009, 4:e5187. 10.1371/journal.pone.0005187, 2664463, 19365543.
24. Farhat M, Greenaway C, Pai M, Menzies D. False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria?. Int J Tuberc Lung Dis 2006, 10:1192-204.
25. Rangaka MX, Wilkinson KA, Seldon R, Van Cutsem G, Meintjes GA, Morroni C, Mouton P, Diwakar L, Connell TG, Maartens G, Wilkinson RJ. The effect of HIV-1 infection on T cell based and skin test detection of tuberculosis infection. Am J Respir Crit Care Med 2007, 175:514-520. 10.1164/rccm.200610-1439OC, 17158278.
26. Kang YA, Lee HW, Yoon HI, Cho B, Han SK, Shim YS, Yim JJ. Discrepancy between the tuberculin skin test and the whole-blood interferon gamma assay for the diagnosis of latent tuberculosis infection in an intermediate tuberculosis-burden country. JAMA 2005, 293:2756-2761. 10.1001/jama.293.22.2756, 15941805.
27. Mahomed H, Hughes EJ, Hawkridge T, Minnies D, Simon E, Little F, Hanekom WA, Geiter L, Hussey GD. Comparison of Mantoux skin test with three generations of a whole blood IFN-gamma assay for tuberculosis infection. Int J Tuberc Lung Dis 2006, 10:310-316.
28. Goletti D, Butera O, Bizzoni F, Casetti R, Girardi E, Poccia F. Region of difference 1 antigen-specific CD4_ memory T cells correlate with a favorable outcome of tuberculosis. J Infect Dis 2006, 194:984-992. 10.1086/507427, 16960787.
29. Godkin AJ, Thomas HC, Openshaw PJ. Evolution of epitope-specific memory CD4_ T cells after clearance of hepatitis C virus. J Immunol 2002, 169:2210-2214.
30. Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993, 362:758-61. 10.1038/362758a0, 8469287.