Serum Metabolomics Profiling to Identify Biomarkers for Unstable Angina

BioMed Research International

Volumn 2017, Issue , 2017, Pages

  Yao, Wei ^a   Gao, Yuxia ^a   Wan, Zheng ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; BIOLOGICAL MARKER; CHOLESTEROL; CHOLINE; CREATININE; GLUCOSE; GLUTAMIC ACID; GLYCEROPHOSPHORYLCHOLINE; GLYCINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOXANTHINE; ISOBUTYRIC ACID; ISOLEUCINE; LACTIC ACID; LEUCINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LYSINE; MALONIC ACID; METHANOL; METHIONINE; PHENYLALANINE; PHOSPHORYLCHOLINE; PYRUVIC ACID; SUCCINIC ACID; THREONINE; TRIMETHYLAMINE; UREA; URIC ACID; VALINE; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLOMICS; PROTEIN BLOOD LEVEL; PROTON NUCLEAR MAGNETIC RESONANCE; UNSTABLE ANGINA PECTORIS; UPREGULATION; AGED; BLOOD; CORONARY ARTERY DISEASE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE; RANDOMIZED CONTROLLED TRIAL;

AGED; ANGINA, UNSTABLE; BIOMARKERS; CORONARY DISEASE; FEMALE; HUMANS; MALE; METABOLOMICS; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 85021766052     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2017/7657306     Document Type: Article

References (29)

1. A. Kibos and A. Guerchicoff, "Susceptibility genes for coronary heart disease and myocardial infarction," Acute Cardiac Care, vol. 13, no. 3, pp. 136-142, 2011
2. B. Unal, J. A. Critchley, and S. Capewell, "Explaining the decline in coronary heart diseasemortality in england and wales between 1981 and 2000," Circulation, vol. 109, no. 9, pp. 1101-1107, 2004
3. Y. Yeghiazarians, J. B. Braunstein, A. Askari, and P. H. Stone, "Unstable angina pectoris," New England Journal of Medicine, vol. 342, no. 2, pp. 101-114, 2000
4. J. L. Anderson, B. D. Horne, S. M. Stevens et al., "Randomized trial of genotype-guided versus standard warfarin dosing in patients initiating oral anticoagulation," Circulation, vol. 116, no. 22, pp. 2563-2570, 2007
5. C. Delles, E. Schiffer, C. Von Zur Muhlen et al., "Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 subjects," Journal of Human Hypertension, vol. 24, no. 10, p. 698, 2010
6. T. Reichlin, W. Hochholzer, S. Bassetti et al., "Early diagnosis of myocardial infarction with sensitive cardiac troponin assays," New England Journal of Medicine, vol. 361, no. 9, pp. 858-867, 2009
7. C. E.Wheelock, A.M.Wheelock, S. Kawashima et al., "Systems biology approaches and pathway tools for investigating cardiovascular disease," Molecular BioSystems, vol. 5, no. 6, pp. 588-602, 2009
8. J. K. Nicholson and J. C. Lindon, "Systems biology: metabonomics," Nature, vol. 455, no. 7216, pp. 1054-1056, 2008
9. M. H.Abu Bakar, M. R. Sarmidi, K. Cheng et al., "Metabolomics-the complementary field in systems biology: a review on obesity and type 2 diabetes," Molecular BioSystems, vol. 11, no. 7, pp. 1742-1774, 2015
10. J. Y. Jung, H.-S. Lee, D.-G. Kang et al., "1H-NMR-based metabolomics study of cerebral infarction," Stroke, vol. 42, no. 5, pp. 1282-1288, 2011
11. P. Bernini, I. Bertini, C. Luchinat, L. Tenori, and A. Tognaccini, "The cardiovascular risk of healthy individuals studied by NMR metabonomics of plasma samples," Journal of Proteome Research, vol. 10, no. 11, pp. 4983-4992, 2011
12. V. Bodi, J. Sanchis, J. M. Morales et al., "Metabolomic profile of human myocardial ischemia by nuclear magnetic resonance spectroscopy of peripheral blood serum: a translational study based on transient coronary occlusion models," Journal of the American College of Cardiology, vol. 59, no. 18, pp. 1629-1641, 2012
13. W. B. Dunn, D. I. Broadhurst, S. M. Deepak et al., "Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate," Metabolomics, vol. 3, no. 4, pp. 413-426, 2007
14. K. Akira, S. Masu, M. Imachi, H. Mitome, M. Hashimoto, and T. Hashimoto, "1H NMR-based metabonomic analysis of urine from young spontaneously hypertensive rats," Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 3, pp. 550-556, 2008
15. H. Xiao, B. E. Tan, M. M. Wu et al., "Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: II. Intestinal morphology and function," Journal of Animal Science, vol. 91, no. 10, pp. 4750-4756, 2013
16. M. B. Bizino, S. Hammer, and H. J. Lamb, "Metabolic imaging of the human heart: clinical application of magnetic resonance spectroscopy," Heart, vol. 100, no. 11, pp. 881-890, 2014
17. M. Trupp, P. Jonsson, A. Ohrfelt et al., "Metabolite and peptide levels in plasma and CSF differentiating healthy controls from patients with newly diagnosed parkinson's disease," Journal of Parkinson's Disease, vol. 4, no. 3, pp. 549-560, 2014
18. J. Y. Park, S.-H. Lee, M.-J. Shin, and G.-S. Hwang, "Alteration in metabolic signature and lipid metabolism in patients with angina pectoris and myocardial infarction," PLoS ONE, vol. 10, no. 8, Article ID e0135228, 2015
19. M. M.Wright,A. G.Howe, andV. Zaremberg, "Cellmembranes and apoptosis: role of cardiolipin, phosphatidylcholine, and anticancer lipid analogues," Biochemistry and Cell Biology, vol. 82, no. 1, pp. 18-26, 2004
20. A. K.Walker, R. L. Jacobs, J. L.Watts et al., "Aconserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans," Cell, vol. 147, no. 4, pp. 840-852, 2011
21. S. Dimmeler, C. Hermann, and A. M. Zeiher, "Apoptosis of endothelial cells. contribution to the pathophysiology of atherosclerosis" European Cytokine Network, vol. 9, no. 4, 697 pages, 1998
22. C. B. Granger, R. J. Goldberg, O. Dabbous et al., "Predictors of hospital mortality in the global registry of acute coronary events," Archives of Internal Medicine, vol. 163, no. 19, pp. 2345-2353, 2003
23. R. T. Saygitov, M. G. Glezer, and S. V. Semakina, "Blood urea nitrogen and creatinine levels at admission for mortality risk assessment in patients with acute coronary syndromes," Emergency Medicine Journal, vol. 27, no. 2, pp. 105-109, 2010
24. J. Carrola, C. M. Rocha, A. S. Barros et al., "Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine," Journal of Proteome Research, vol. 10, no. 1, pp. 221-230, 2011
25. K. J. Drake, V. Y. Sidorov, O. P. McGuinness, D. H.Wasserman, and J. P. Wikswo, "Amino acids as metabolic substrates during cardiac ischemia," Experimental Biology and Medicine, vol. 237, no. 12, pp. 1369-1378, 2012
26. G. Liu, S. Chen, J. Zhong, K. Teng, and Y. Yin, "Crosstalk between tryptophan metabolism and cardiovascular disease, mechanisms, and therapeutic implications," OxidativeMedicine and Cellular Longevity, vol. 2017, Article ID 1602074, 5 pages, 2017
27. G. Liu,W. Ren, J. Fang, C. A. Hu et al., "L-Glutamine and Larginine protect against enterotoxigenic Escherichia coli infection via intestinal innate immunity in mice," Amino Acids, pp. 1-10, 2017
28. A. T. Turer, R. D. Stevens, J. R. Bain et al., "Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion," Circulation, vol. 119, no. 13, pp. 1736-1746, 2009
29. M. Nishimura, H. Tanaka, N. Homma, T. Matsuzawa, and Y. Watanabe, "Ionicmechanisms of the depression of automaticity and conduction in the rabbit atrioventricular node caused by hypoxia ormetabolic inhibition and protective action of glucose and valine,"The American Journal of Cardiology, vol. 64, no. 20, pp. J24-J28, 1989.