Prognostic Significance of Remote Myocardium Alterations Assessed by Quantitative Noncontrast T1 Mapping in ST-Segment Elevation Myocardial Infarction

JACC: Cardiovascular Imaging

Volumn 11, Issue 3, 2018, Pages 411-419

  Reinstadler, Sebastian J ^a,b,c   Stiermaier, Thomas ^a,b   Liebetrau, Johanna ^a,b   Fuernau, Georg ^a,b   Eitel, Charlotte ^a,b   de Waha, Suzanne ^a,b   Desch, Steffen ^a,b   Reil, Jan Christian ^a,b   Pöss, Janine ^a,b   Metzler, Bernhard ^c   Lücke, Christian ^d   Gutberlet, Matthias ^d   Schuler, Gerhard ^d   Thiele, Holger ^a,b   Eitel, Ingo ^a,b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

cardiac magnetic resonance imaging; myocardial infarction; prognosis; remote myocardium; T1 mapping

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRASUGREL; TICAGRELOR; TROPONIN T;

ADULT; AGED; ARTICLE; CARDIAC MUSCLE; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL OUTCOME; CONGESTIVE HEART FAILURE; CORE LABORATORY; DISEASE MARKER; FEMALE; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HUMAN; MAJOR ADVERSE CARDIAC EVENT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THROMBUS ASPIRATION; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE EXACERBATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; TIME FACTOR; TREATMENT OUTCOME;

AGED; DISEASE PROGRESSION; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIUM; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECURRENCE; RISK FACTORS; ST ELEVATION MYOCARDIAL INFARCTION; TIME FACTORS; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 85020786353     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2017.03.015     Document Type: Article

References (35)

1. Pfeffer, M.A., Braunwald, E., Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation 81 (1990), 1161–1172.
2. Cleutjens, J.P., Verluyten, M.J., Smiths, J.F., Daemen, M.J., Collagen remodeling after myocardial infarction in the rat heart. Am J Pathol 147 (1995), 325–338.
3. Kramer, C.M., Rogers, W.J., Theobald, T.M., Power, T.P., Geskin, G., Reichek, N., Dissociation between changes in intramyocardial function and left ventricular volumes in the eight weeks after first anterior myocardial infarction. J Am Coll Cardiol 30 (1997), 1625–1632.
4. Bogaert, J., Bosmans, H., Maes, A., Suetens, P., Marchal, G., Rademakers, F.E., Remote myocardial dysfunction after acute anterior myocardial infarction: impact of left ventricular shape on regional function: a magnetic resonance myocardial tagging study. J Am Coll Cardiol 35 (2000), 1525–1534.
5. Husser, O., Chaustre, F., Sanchis, J., et al. Function of remote non-infarcted myocardium after STEMI: analysis with cardiovascular magnetic resonance. Int J Cardiovasc Imaging 28 (2012), 2057–2064.
6. Messroghli, D.R., Radjenovic, A., Kozerke, S., Higgins, D.M., Sivananthan, M.U., Ridgway, J.P., Modified Look-Locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart. Magn Reson Med 52 (2004), 141–146.
7. Puntmann, V.O., Peker, E., Chandrashekhar, Y., Nagel, E., T1 mapping in characterizing myocardial disease: a comprehensive review. Circ Res 119 (2016), 277–299.
8. Taylor, A.J., Salerno, M., Dharmakumar, R., Jerosch-Herold, M., T1 mapping: basic techniques and clinical applications. J Am Coll Cardiol Img 9 (2016), 67–81.
9. Bull, S., White, S.K., Piechnik, S.K., et al. Human non-contrast T1 values and correlation with histology in diffuse fibrosis. Heart 99 (2013), 932–937.
10. Carrick, D., Haig, C., Rauhalammi, S., et al. Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison with contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. Eur Heart J 37 (2016), 1044–1059.
11. Hinojar, R., Varma, N., Child, N., et al. T1 mapping in discrimination of hypertrophic phenotypes: hypertensive heart disease and hypertrophic cardiomyopathy: findings from the International T1 Multicenter Cardiovascular Magnetic Resonance Study. Circ Cardiovasc Imaging, 8, 2015, e003285.
12. Puntmann, V.O., Carr-White, G., Jabbour, A., et al. T1-mapping and outcome in nonischemic cardiomyopathy: all-cause mortality and heart failure. J Am Coll Cardiol Img 9 (2016), 40–50.
13. Chan, W., Duffy, S.J., White, D.A., et al. Acute left ventricular remodeling following myocardial infarction: coupling of regional healing with remote extracellular matrix expansion. J Am Coll Cardiol Img 5 (2012), 884–893.
14. Ugander, M., Oki, A.J., Hsu, L.Y., et al. Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology. Eur Heart J 33 (2012), 1268–1278.
15. Carrick, D., Haig, C., Rauhalammi, S., et al. Pathophysiology of LV remodeling in survivors of STEMI: inflammation, remote myocardium, and prognosis. J Am Coll Cardiol 8 (2015), 779–789.
16. Eitel, I., Stiermaier, T., Rommel, K.P., et al. Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial. Eur Heart J 36 (2015), 3049–3057.
17. Eitel, I., Desch, S., Fuernau, G., et al. Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction. J Am Coll Cardiol 55 (2010), 2470–2479.
18. Thiele, H., Kappl, M.J., Conradi, S., Niebauer, J., Hambrecht, R., Schuler, G., Reproducibility of chronic and acute infarct size measurement by delayed enhancement-magnetic resonance imaging. J Am Coll Cardiol 47 (2006), 1641–1645.
19. Desch, S., Siegemund, A., Scholz, U., et al. Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction. Clin Res Cardiol 101 (2012), 117–124.
20. Bohnen, S., Radunski, U.K., Lund, G.K., et al. Performance of T1 and T2 mapping cardiovascular magnetic resonance to detect active myocarditis in patients with recent-onset heart failure. Circ Cardiovasc Imaging, 8, 2015, e003073.
21. Eitel, I., de Waha, S., Wohrle, J., et al. Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction. J Am Coll Cardiol 64 (2014), 1217–1226.
22. DeLong, E.R., DeLong, D.M., Clarke-Pearson, D.L., Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44 (1988), 837–845.
23. Reinstadler, S.J., Thiele, H., Eitel, I., Risk stratification by cardiac magnetic resonance imaging after ST-elevation myocardial infarction. Curr Opin Cardiol 30 (2015), 681–689.
24. Stone, G.W., Selker, H.P., Thiele, H., et al. Relationship between infarct size and outcomes following primary PCI: patient-level analysis from 10 randomized trials. J Am Coll Cardiol 67 (2016), 1674–1683.
25. Lee, W.W., Marinelli, B., van der Laan, A.M., et al. PET/MRI of inflammation in myocardial infarction. J Am Coll Cardiol 59 (2012), 153–163.
26. Seropian, I.M., Toldo, S., Van Tassell, B.W., Abbate, A., Anti-inflammatory strategies for ventricular remodeling following ST-segment elevation acute myocardial infarction. J Am Coll Cardiol 63 (2014), 1593–1603.
27. Mahmod, M., Piechnik, S.K., Levelt, E., et al. Adenosine stress native T1 mapping in severe aortic stenosis: evidence for a role of the intravascular compartment on myocardial T1 values. J Cardiovasc Magn Reson, 16, 2014, 92.
28. Verhaert, D., Thavendiranathan, P., Giri, S., et al. Direct T2 quantification of myocardial edema in acute ischemic injury. J Am Coll Cardiol Img 4 (2011), 269–278.
29. Kramer, C.M., Rogers, W.J., Park, C.S., et al. Regional myocyte hypertrophy parallels regional myocardial dysfunction during post-infarct remodeling. J Mol Cell Cardiol 30 (1998), 1773–1778.
30. Melillo, G., Lima, J.A., Judd, R.M., Goldschmidt-Clermont, P.J., Silverman, H.S., Intrinsic myocyte dysfunction and tyrosine kinase pathway activation underlie the impaired wall thickening of adjacent regions during postinfarct left ventricular remodeling. Circulation 93 (1996), 1447–1458.
31. Grobner, T., Prischl, F.C., Gadolinium and nephrogenic systemic fibrosis. Kidney Int 72 (2007), 260–264.
32. Kanda, T., Fukusato, T., Matsuda, M., et al. Gadolinium-based contrast agent accumulates in the brain even in subjects without severe renal dysfunction: evaluation of autopsy brain specimens with inductively coupled plasma mass spectroscopy. Radiology 276 (2015), 228–232.
33. Moreno-Gonzalez, A., Korte, F.S., Dai, J., et al. Cell therapy enhances function of remote non-infarcted myocardium. J Mol Cell Cardiol 47 (2009), 603–613.
34. Fernandez-Jimenez, R., Sanchez-Gonzalez, J., Aguero, J., et al. Myocardial edema after ischemia/reperfusion is not stable and follows a bimodal pattern: imaging and histological tissue characterization. J Am Coll Cardiol 65 (2015), 315–323.
35. Rogers, T., Dabir, D., Mahmoud, I., et al. Standardization of T1 measurements with MOLLI in differentiation between health and disease—the ConSept study. J Cardiovasc Magn Reson, 15, 2013, 78.