Relationship between Infarct Size and Outcomes Following Primary PCI Patient-Level Analysis from 10 Randomized Trials

Journal of the American College of Cardiology

Volumn 67, Issue 14, 2016, Pages 1674-1683

  Stone, Gregg W ^a   Selker, Harry P ^b   Thiele, Holger ^c   Patel, Manesh R ^d   Udelson, James E ^b   Ohman, E Magnus ^d   Maehara, Akiko ^a   Eitel, Ingo ^c   Granger, Christopher B ^d   Jenkins, Paul L ^e   Nichols, Melissa ^a   Ben Yehuda, Ori ^a  

^a NewYork Presbyterian Hospital   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c University Heart Center Lübeck   (Germany)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e BASSETT MEDICAL CENTER   (United States)

Author keywords

angioplasty; infarct size; myocardial infarction; prognosis

Indexed keywords

METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

ADULT; AGED; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CARDIOVASCULAR PARAMETERS; DIABETES MELLITUS; FEMALE; FOLLOW UP; HEART FAILURE; HEART INFARCTION SIZE; HEART REINFARCTION; HOSPITALIZATION; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SMOKING; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THROMBOLYSIS IN MYOCARDIAL INFARCTION FLOW; TIME TO TREATMENT; FACTUAL DATABASE; META ANALYSIS; MIDDLE AGED; MYOCARDIAL INFARCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; RECURRENT DISEASE; SCINTISCANNING; STATISTICS AND NUMERICAL DATA; SURVIVAL RATE;

AGED; DATABASES, FACTUAL; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HOSPITALIZATION; HUMANS; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PATIENT OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECURRENCE; SURVIVAL RATE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84962150632     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2016.01.069     Document Type: Article

References (33)

1. E.G. Nabel, and E. Braunwald A tale of coronary artery disease and myocardial infarction N Engl J Med 366 2012 54 63
2. T. Baardman, W.T. Hermens, T. Lenderink, and et al. Differential effects of tissue plasminogen activator and streptokinase on infarct size and on rate of enzyme release: influence of early infarct related artery patency. The GUSTO Enzyme Substudy Eur Heart J 17 1996 237 246
3. A. Schömig, A. Kastrati, J. Dirschinger, et al. for the Stent versus Thrombolysis for Occluded Coronary Arteries in Patients with Acute Myocardial Infarction Study Investigators Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction N Engl J Med 343 2000 385 391
4. E.C. Keeley, J.A. Boura, and C.L. Grines Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials Lancet 361 2003 13 20
5. D.P. Chew, F.A. Anderson, A. Avezum, and et al. Six-month survival benefits associated with clinical guideline recommendations in acute coronary syndromes Heart 96 2010 1201 1206
6. B.J. Gersh, G.W. Stone, H.D. White, and D.R. Holmes Jr. Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: is the slope of the curve the shape of the future? JAMA 293 2005 979 986
7. R.J. Burns, R.J. Gibbons, Q. Yi, and et al. The relationships of left ventricular ejection fraction, end-systolic volume index and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis J Am Coll Cardiol 39 2002 30 36
8. G.W. Stone, J. Webb, D.A. Cox, and et al. Distal microcirculatory protection during percutaneous coronary intervention in acute ST-segment elevation myocardial infarction: a randomized controlled trial JAMA 293 2005 1063 1072
9. G.W. Stone, J.L. Martin, M.J. de Boer, and et al. Effect of supersaturated oxygen delivery on infarct size after percutaneous coronary intervention in acute myocardial infarction Circ Cardiovasc Interv 2 2009 366 375
10. H.P. Selker, J.R. Beshansky, P.R. Sheehan, and et al. Out-of-hospital administration of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE randomized controlled trial JAMA 307 2012 1925 1933
11. M.R. Patel, S.G. Worthley, A. Stebbins, and et al. Pexelizumab and infarct size in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention: a delayed enhancement cardiac magnetic resonance substudy from the APEX-AMI trial J Am Coll Cardiol Img 3 2010 52 60
12. H. Thiele, K. Schindler, J. Friedenberger, and et al. Intracoronary compared with intravenous bolus abciximab application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: the randomized Leipzig immediate percutaneous coronary intervention abciximab IV versus IC in ST-elevation myocardial infarction trial Circulation 118 2008 49 57
13. H. Thiele, L. Hildebrand, C. Schirdewahn, and et al. Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: the LIPSIA-N-ACC (Prospective, Single-Blind, Placebo-Controlled, Randomized Leipzig Immediate PercutaneouS Coronary Intervention Acute Myocardial Infarction N-ACC) trial J Am Coll Cardiol 55 2010 2201 2209
14. H. Thiele, I. Eitel, C. Meinberg, and et al. Randomized comparison of pre-hospital-initiated facilitated percutaneous coronary intervention versus primary percutaneous coronary intervention in acute myocardial infarction very early after symptom onset: the LIPSIA-STEMI trial (Leipzig immediate prehospital facilitated angioplasty in ST-segment myocardial infarction) J Am Coll Cardiol Intv 4 2011 605 614
15. M.R. Patel, R.W. Smalling, H. Thiele, and et al. Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial JAMA 306 2011 1329 1337
16. I. Eitel, J. Wöhrle, H. Suenkel, and et al. Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial J Am Coll Cardiol 61 2013 1447 1454
17. G.W. Stone, A. Maehara, B. Witzenbichler, and et al. Intracoronary abciximab and aspiration thrombectomy in patients with large anterior myocardial infarction: the INFUSE-AMI randomized trial JAMA 307 2012 1817 1826
18. M.J. Pencina, R.B. D'Agostino Sr., R.B. D'Agostino Jr., and R.S. Vasan Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond Stat Med 27 2008 157 172
19. T.D. Miller, T.F. Christian, M.R. Hopfenspirger, and et al. Infarct size after acute myocardial infarction measured by quantitative tomographic 99mtc sestamibi imaging predicts subsequent mortality Circulation 92 1995 334 341
20. G.W. Stone, S.R. Dixon, C.L. Grines, and et al. Predictors of infarct size after primary coronary angioplasty in acute myocardial infarction from pooled analysis from four contemporary trials Am J Cardiol 100 2007 1370 1375
21. G. De Luca, H. Suryapranata, J.P. Ottervanger, and E.M. Antman Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay counts Circulation 109 2004 1223 1225
22. A. Halkin, M. Singh, E. Nicolsky, and et al. Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction. The CADILLAC risk score J Am Coll Cardiol 45 2005 1397 1405
23. G.W. Stone, D. Cox, E. Garcia, and et al. Normal flow (TIMI-3) before mechanical reperfusion therapy is an independent determinant of survival in acute myocardial infarction: analysis from the primary angioplasty in myocardial infarction trials Circulation 104 2001 636 641
24. E.I. Lev, R. Kornowski, H. Vaknin-Assa, and et al. Comparison of the predictive value of four different risk scores for outcome of patients with ST-elevation acute myocardial infarction undergoing primary percutaneous coronary intervention Am J Cardiol 102 2008 6 11
25. S. Blecker, M. Paul, G. Taksler, G. Ogedegbe, and S. Katz Heart failure associated hospitalizations in the United States J Am Coll Cardiol 61 2013 1259 1267
26. F. Zannad, N. Agrinier, and F. Alla Heart failure burden and therapy Europace 11 Suppl 5 2009 1 9
27. A.P. Ambrosy, G.C. Fonarow, J. Butler, and et al. The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries J Am Coll Cardiol 63 2014 1123 1133
28. R.L. Prentice Surrogate end points in clinical trials: definition and operational criteria Stat Med 8 1989 431 440
29. T.R. Fleming, and D.L. DeMets Surrogate end points in clinical trials: are we being misled? Ann Intern Med 125 1996 605 613
30. S.J. Kernis, K.J. Harjai, G.W. Stone, and et al. The incidence, predictors and outcomes of early reinfarction after primary angioplasty for acute myocardial infarction J Am Coll Cardiol 42 2003 1173 1177
31. S.G. Stone, G.W. Serrao, R. Mehran, and et al. Incidence, predictors, and implications of reinfarction after primary percutaneous coronary intervention in ST-segment-elevation myocardial infarction: the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction Trial Circ Cardiovasc Interv 7 2014 543 551
32. A. Wagner, H. Mahrholdt, T.A. Holly, and et al. Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study Lancet 361 2003 374 379
33. L. Schwartz Longacre, R.A. Kloner, A.E. Arai, and et al. New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop Circulation 124 2011 1172 1179