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Volumn 7, Issue 1, 2017, Pages

Comparisons of the biodistribution and toxicological examinations after repeated intravenous administration of silver and gold nanoparticles in mice

Author keywords

[No Author keywords available]

Indexed keywords

GOLD; METAL NANOPARTICLE; SILVER;

EID: 85020742376     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-03015-1     Document Type: Article
Times cited : (191)

References (49)
  • 1
    • 77951641729 scopus 로고    scopus 로고
    • Properties and applications of colloidal nonspherical noble metal nanoparticles
    • Sau, T. K., Rogach, A. L., Jäckel, F., Klar, T. A., Feldmann, J. Properties and applications of colloidal nonspherical noble metal nanoparticles. Adv. Mater. 22, 1805-25, doi:10.1002/adma.200902557 (2010).
    • (2010) Adv. Mater. , vol.22 , pp. 1805-1825
    • Sau, T.K.1    Rogach, A.L.2    Jäckel, F.3    Klar, T.A.4    Feldmann, J.5
  • 2
    • 84866873854 scopus 로고    scopus 로고
    • Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats
    • Dziendzikowska, K., et al. Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats. J. Appl. Toxicol. 32, 920-928, doi:10.1002/jat.2758 (2012).
    • (2012) J. Appl. Toxicol. , vol.32 , pp. 920-928
    • Dziendzikowska, K.1
  • 3
    • 84865588812 scopus 로고    scopus 로고
    • Distribution, elimination, toxicity of silver nanoparticles and silver ions
    • Zande, M., et al. Distribution, elimination, toxicity of silver nanoparticles and silver ions. ACS Nano 6, 7427-7442, doi:10.1021/nn302649p (2012).
    • (2012) ACS Nano , vol.6 , pp. 7427-7442
    • Zande, M.1
  • 4
    • 67651233657 scopus 로고    scopus 로고
    • Gold nanoparticles in nanomedicine: Preparations, imaging, diagnostics, therapies and toxicity
    • Boisselier, E., Astruc, D. Gold nanoparticles in nanomedicine: Preparations, imaging, diagnostics, therapies and toxicity. Chem. Soc. Rev. 38, 1759-82, doi:10.1039/b806051g (2009).
    • (2009) Chem. Soc. Rev. , vol.38 , pp. 1759-1782
    • Boisselier, E.1    Astruc, D.2
  • 5
    • 46749122210 scopus 로고    scopus 로고
    • Gold nanoparticles in delivery applications
    • Ghosh, P., Han, G., De, M., Kim, C. K., Rotello, V. M. Gold nanoparticles in delivery applications. Adv. Drug Deliver. Rev 60, 1307-15, doi:10.1016/j.addr.2008.03.016 (2008).
    • (2008) Adv. Drug Deliver. Rev , vol.60 , pp. 1307-1315
    • Ghosh, P.1    De, H.G.M.2    Kim, C.K.3    Rotello, V.M.4
  • 6
    • 74449089602 scopus 로고    scopus 로고
    • Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rat
    • Balasubramanian, S. K., et al. Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rat. Biomaterials 31, 2034-42, doi:10.1016/j.biomaterials.2009.11.079 (2010).
    • (2010) Biomaterials , vol.31 , pp. 2034-2042
    • Balasubramanian, S.K.1
  • 7
    • 82955207599 scopus 로고    scopus 로고
    • The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells
    • Lankoff, A., et al. The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells. Toxicol. Lett. 208, 197-213, doi:10.1016/j.toxlet.2011.11.006 (2012).
    • (2012) Toxicol. Lett. , vol.208 , pp. 197-213
    • Lankoff, A.1
  • 8
    • 38449108160 scopus 로고    scopus 로고
    • Gold nanoparticles induce oxidative damage in lung fibroblasts in vitro
    • Li, J. J., et al. Gold nanoparticles induce oxidative damage in lung fibroblasts in vitro. Adv. Mater. 20, 138-42, doi:10.1002/adma.200701853 (2008).
    • (2008) Adv. Mater. , vol.20 , pp. 138-142
    • Li, J.J.1
  • 9
    • 84889004661 scopus 로고    scopus 로고
    • Differential cytotoxic effects of gold nanoparticles in different mammalian cell lines
    • Chueha, P. J., Lianga, R. Y., Leea, Y. H., Zenga, Z., Chuang, S. M. Differential cytotoxic effects of gold nanoparticles in different mammalian cell lines. J. Hazard. Mater. 264, 303-312, doi:10.1016/j.jhazmat.2013.11.031 (2014).
    • (2014) J. Hazard. Mater. , vol.264 , pp. 303-312
    • Chueha, P.J.1    Lianga, R.Y.2    Leea, Y.H.3    Zenga, Z.4    Chuang, S.M.5
  • 10
    • 84974694693 scopus 로고    scopus 로고
    • Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis
    • Kovács, D., et al. Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis. Sci. Rep. 6, doi:10.1038/srep27902 (2016).
    • (2016) Sci. Rep. , vol.6
    • Kovács, D.1
  • 11
    • 84878038535 scopus 로고    scopus 로고
    • Silver nanoparticles decrease body weight and locomotor activity in adult male rats
    • Zhang, Y., et al. Silver nanoparticles decrease body weight and locomotor activity in adult male rats. Small 9, 1715-20, doi:10.1002/smll.201201548 (2013).
    • (2013) Small , vol.9 , pp. 1715-1720
    • Zhang, Y.1
  • 12
    • 42649083989 scopus 로고    scopus 로고
    • Lung function changes in Sprague-Dawley rats after prolonged inhalation exposure to silver nanoparticles
    • Sung, J. H., et al. Lung function changes in Sprague-Dawley rats after prolonged inhalation exposure to silver nanoparticles. Inhal. Toxicol. 20, 567-74, doi:10.1080/08958370701874671 (2008).
    • (2008) Inhal. Toxicol. , vol.20 , pp. 567-574
    • Sung, J.H.1
  • 13
    • 79952311136 scopus 로고    scopus 로고
    • Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration
    • Hirn, S., et al. Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration. Eur. J. Pharm. Biopharm. 77, 407-16, doi:10.1016/j.ejpb.2010.12.029 (2011).
    • (2011) Eur. J. Pharm. Biopharm. , vol.77 , pp. 407-416
    • Hirn, S.1
  • 14
    • 84880891190 scopus 로고    scopus 로고
    • Biopersistence of silver nanoparticles in tissues from Sprague-Dawley rats
    • Lee, J. H., et al. Biopersistence of silver nanoparticles in tissues from Sprague-Dawley rats. Part. Fibre Toxicol. 10, 36, doi:10.1186/1743-8977-10-36 (2013).
    • (2013) Part. Fibre Toxicol. , vol.10 , pp. 36
    • Lee, J.H.1
  • 15
    • 77949492727 scopus 로고    scopus 로고
    • Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice
    • Lasagna-Reeves, C., et al. Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice. Biochem. Bioph. Res. Co 393, 649-55, doi:10.1016/j.bbrc.2010.02.046 (2010).
    • (2010) Biochem. Bioph. Res. Co , vol.393 , pp. 649-655
    • Lasagna-Reeves, C.1
  • 16
    • 84894586147 scopus 로고    scopus 로고
    • Differential toxicological response to positively and negatively charged nanoparticles in the rat brain
    • Knudsen, K. B., et al. Differential toxicological response to positively and negatively charged nanoparticles in the rat brain. Nanotoxicology 8, 764-74, doi:10.3109/17435390.2013.829589 (2014).
    • (2014) Nanotoxicology , vol.8 , pp. 764-774
    • Knudsen, K.B.1
  • 17
    • 84935017858 scopus 로고    scopus 로고
    • Surface chemistry but not aspect ratio mediates the biological toxicity of gold nanorods in vitro and in vivo
    • Wan, J., et al. Surface chemistry but not aspect ratio mediates the biological toxicity of gold nanorods in vitro and in vivo. Sci. Rep. 5, doi:10.1038/srep11398 (2015).
    • (2015) Sci. Rep. , vol.5
    • Wan, J.1
  • 18
    • 84947579486 scopus 로고    scopus 로고
    • Shape-dependent skin penetration of silver nanoparticles: Does it really matter
    • Tak, Y. K., Pal, S., Naoghare, P. K., Rangasamy, S., Song, J. M. Shape-dependent skin penetration of silver nanoparticles: Does it really matter Sci. Rep. 5, doi:10.1038/srep16908 (2015).
    • (2015) Sci. Rep. , vol.5
    • Tak, Y.K.1    Pal, S.2    Naoghare, P.K.3    Rangasamy, S.4    Song, J.M.5
  • 19
    • 78650452336 scopus 로고    scopus 로고
    • Dose-dependent in-vivo toxicity assessment of silver nanoparticle in Wistar Rats
    • Tiwari, D. K., Jin, T., Behari, J. Dose-dependent in-vivo toxicity assessment of silver nanoparticle in Wistar Rats. Toxicol. Mech. Method 21, 13-24, doi:10.3109/15376516.2010.529184 (2011).
    • (2011) Toxicol. Mech. Method , vol.21 , pp. 13-24
    • Tiwari, D.K.1    Jin, T.2    Behari, J.3
  • 20
    • 42649143562 scopus 로고    scopus 로고
    • Twenty-eight-day oral toxicity, genotoxicity, gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats
    • Kim, Y. S., et al. Twenty-eight-day oral toxicity, genotoxicity, gender-related tissue distribution of silver nanoparticles in Sprague-Dawley rats. Inhal. Toxicol. 20, 575-83, doi:10.1080/08958370701874663 (2008).
    • (2008) Inhal. Toxicol. , vol.20 , pp. 575-583
    • Kim, Y.S.1
  • 21
    • 84866863235 scopus 로고    scopus 로고
    • Acute toxic effects and gender-related biokinetics of silver nanoparticles following an intravenous injection in mice
    • Xue, Y., et al. Acute toxic effects and gender-related biokinetics of silver nanoparticles following an intravenous injection in mice. J. Appl. Toxicol. 32, 890-99, doi:10.1002/jat.2742 (2012).
    • (2012) J. Appl. Toxicol. , vol.32 , pp. 890-899
    • Xue, Y.1
  • 22
    • 77949780454 scopus 로고    scopus 로고
    • A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity
    • Johnston, H. J., et al. A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity. Crit. Rev. Toxicol. 403, 28-46, doi:10.3109/10408440903453074 (2010).
    • (2010) Crit. Rev. Toxicol. , vol.403 , pp. 28-46
    • Johnston, H.J.1
  • 23
    • 64349090027 scopus 로고    scopus 로고
    • Subchronic inhalation toxicity of silver nanoparticles
    • Sung, J. H., et al. Subchronic inhalation toxicity of silver nanoparticles. Toxicol. Sci. 108, 452-61, doi:10.1093/toxsci/kfn246 (2009).
    • (2009) Toxicol. Sci. , vol.108 , pp. 452-461
    • Sung, J.H.1
  • 24
    • 84862856783 scopus 로고    scopus 로고
    • Subacute oral toxicity investigation of nanoparticulate and ionic silver in rats
    • Sung, J. H., et al. Subacute oral toxicity investigation of nanoparticulate and ionic silver in rats. Arch. Toxicol. 86, 543-51, doi:10.1007/s00204-011-0759-1 (2012).
    • (2012) Arch. Toxicol. , vol.86 , pp. 543-551
    • Sung, J.H.1
  • 25
    • 77953958484 scopus 로고    scopus 로고
    • Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection
    • Lipka, J., et al. Biodistribution of PEG-modified gold nanoparticles following intratracheal instillation and intravenous injection. Biomaterials 31, 6574-81, doi:10.1016/j.biomaterials.2010.05.009 (2010).
    • (2010) Biomaterials , vol.31 , pp. 6574-6581
    • Lipka, J.1
  • 26
    • 39649115201 scopus 로고    scopus 로고
    • Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
    • De Jong, W. H., et al. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 29, 1912-19, doi:10.1016/j.biomaterials.2007.12.037 (2008).
    • (2008) Biomaterials , vol.29 , pp. 1912-1919
    • De Jong, W.H.1
  • 27
    • 50649113474 scopus 로고    scopus 로고
    • Biodistribution of colloidal gold nanoparticles after intravenous administration: Effect of particle size
    • Sonavane, G., Tomoda, K., Makino, K. Biodistribution of colloidal gold nanoparticles after intravenous administration: Effect of particle size. Colloid surface B 66, 274-80, doi:10.1016/j.colsurfb.2008.07.004 (2008).
    • (2008) Colloid Surface B , vol.66 , pp. 274-280
    • Sonavane, G.1    Tomoda, K.2    Makino, K.3
  • 28
    • 84881663479 scopus 로고    scopus 로고
    • Systemic and immunotoxicity of silver nanoparticles in an intravenous 28 days repeated dose toxicity study in rats
    • De Jong, W. H., et al. Systemic and immunotoxicity of silver nanoparticles in an intravenous 28 days repeated dose toxicity study in rats. Biomaterials 34, 8333-43, doi:10.1016/j.biomaterials.2013.06.048 (2013).
    • (2013) Biomaterials , vol.34 , pp. 8333-8343
    • De Jong, W.H.1
  • 29
    • 79957633238 scopus 로고    scopus 로고
    • Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate
    • Loeschner, K., et al. Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate. Part. Fibre Toxicol. 8, 18, doi:10.1186/1743-8977-8-18 (2011).
    • (2011) Part. Fibre Toxicol. , vol.8 , pp. 18
    • Loeschner, K.1
  • 30
    • 84906227106 scopus 로고    scopus 로고
    • Quantitatively profiling the dissolution and redistribution of silver nanoparticles in living rats using a knotted reactor-based differentiation scheme
    • Su, C. K., Liu, H. T., Hsia, S. C., Sun, Y. C. Quantitatively profiling the dissolution and redistribution of silver nanoparticles in living rats using a knotted reactor-based differentiation scheme. Anal. Chem. 86, 8267-74, doi:10.1021/ac501691z (2014).
    • (2014) Anal. Chem. , vol.86 , pp. 8267-8274
    • Su, C.K.1    Liu, H.T.2    Hsia, S.C.3    Sun, Y.C.4
  • 31
    • 84944455323 scopus 로고    scopus 로고
    • In vivo integrity of polymer-coated gold nanoparticles
    • Kreyling, W. G., et al. In vivo integrity of polymer-coated gold nanoparticles. Nat. Nanotechnol 10, 619-623, doi:10.1038/nnano.2015.111 (2015).
    • (2015) Nat. Nanotechnol , vol.10 , pp. 619-623
    • Kreyling, W.G.1
  • 32
    • 84908564122 scopus 로고    scopus 로고
    • Short-and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration
    • Fraga, S., et al. Short-and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration. Nanomed.-Nanotechnol 10, 1757-1766, doi:10.1016/j.nano.2014.06.005 (2014).
    • (2014) Nanomed.-Nanotechnol , vol.10 , pp. 1757-1766
    • Fraga, S.1
  • 33
    • 57349139366 scopus 로고    scopus 로고
    • Biodistribution of 1.4-A nd 18-nm gold particles in rats
    • Semmler-Behnke, M., et al. Biodistribution of 1.4-A nd 18-nm gold particles in rats. Small 4, 2108-2111, doi:10.1002/smll.200800922 (2008).
    • (2008) Small , vol.4 , pp. 2108-2111
    • Semmler-Behnke, M.1
  • 34
    • 69049115300 scopus 로고    scopus 로고
    • Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos
    • Bar-Ilan, O., Albrecht, R. M., Fako, V. E., Furgeson, D. Y. Toxicity assessments of multisized gold and silver nanoparticles in zebrafish embryos. Small 5, 1897-10, doi:10.1002/smll.200801716 (2009).
    • (2009) Small , vol.5 , pp. 1897-1910
    • Bar-Ilan, O.1    Albrecht, R.M.2    Fako, V.E.3    Furgeson, D.Y.4
  • 35
    • 79957922713 scopus 로고    scopus 로고
    • In vivo distribution, pharmacokinetics, toxicity of aqueous synthesized cadmium-containing quantum dots
    • Su, Y., et al. In vivo distribution, pharmacokinetics, toxicity of aqueous synthesized cadmium-containing quantum dots. Biomaterials 32, 5855-62, doi:10.1016/j.biomaterials.2011.04.063 (2011).
    • (2011) Biomaterials , vol.32 , pp. 5855-5862
    • Su, Y.1
  • 36
    • 84916899140 scopus 로고    scopus 로고
    • Size dpendent bodistribution and txicokinetics of ion oide mgnetic nnoparticles in mce
    • Yang, L., et al. Size dpendent bodistribution and txicokinetics of ion oide mgnetic nnoparticles in mce. Nanoscale 7, 625-36, doi:10.1039/c4nr05061d (2015).
    • (2015) Nanoscale , vol.7 , pp. 625-636
    • Yang, L.1
  • 37
    • 84875254244 scopus 로고    scopus 로고
    • Biodistribution, pharmacokinetics and toxicology Ag2S of near-infrared quantum dots in mice
    • Zhang, Y., et al. Biodistribution, pharmacokinetics and toxicology Ag2S of near-infrared quantum dots in mice. Biomaterials 34, 3639-46, doi:10.1016/j.biomaterials.2013.01.089 (2013).
    • (2013) Biomaterials , vol.34 , pp. 3639-3646
    • Zhang, Y.1
  • 38
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • Nel, A., Xia, T., Mädler, L., Li, N. Toxic potential of materials at the nanolevel. Science 311, 622-27, doi:10.1126/science.1114397 (2006).
    • (2006) Science , vol.311 , pp. 622-627
    • Nel, A.1    Xia, T.2    Mädler, L.3    Li, N.4
  • 39
    • 84855606424 scopus 로고    scopus 로고
    • Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure
    • Nabeshi, H., et al. Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure. Nanotechnology 23, 045101, doi:10.1088/0957-4484/23/4/045101 (2012).
    • (2012) Nanotechnology , vol.23 , pp. 045101
    • Nabeshi, H.1
  • 40
    • 84890352082 scopus 로고    scopus 로고
    • Toxicity and biodistribution of aqueous synthesized ZnS and ZnO quantum dots in mice
    • Yang, Y., et al. Toxicity and biodistribution of aqueous synthesized ZnS and ZnO quantum dots in mice. Nanotoxicology 8, 107-16, doi:10.3109/17435390.2012.760014 (2014).
    • (2014) Nanotoxicology , vol.8 , pp. 107-116
    • Yang, Y.1
  • 41
    • 84882846247 scopus 로고    scopus 로고
    • The role of surface chemistry in determining in vivo biodistribution and toxicity of CdSe/ZnS core-shell quantum dots
    • Tang, Y., et al. The role of surface chemistry in determining in vivo biodistribution and toxicity of CdSe/ZnS core-shell quantum dots. Biomaterials 34, 8741-55, doi:10.1016/j.biomaterials.2013.07.087 (2013).
    • (2013) Biomaterials , vol.34 , pp. 8741-8755
    • Tang, Y.1
  • 42
    • 34547764374 scopus 로고    scopus 로고
    • Twenty-eight-day inhalation toxicity study of silver nanoparticles in Sprague-Dawley rats
    • Ji, J. H., et al. Twenty-eight-day inhalation toxicity study of silver nanoparticles in Sprague-Dawley rats. Inhal. Toxicol. 19, 857-71, doi:10.1080/08958370701432108 (2007).
    • (2007) Inhal. Toxicol. , vol.19 , pp. 857-871
    • Ji, J.H.1
  • 43
    • 79955060872 scopus 로고    scopus 로고
    • Bioavailability and toxicokinetics of citrate-coated silver nanoparticles in rats
    • Park, K., et al. Bioavailability and toxicokinetics of citrate-coated silver nanoparticles in rats. Arch. Pharm. Res. 34, 153-58, doi:10.1007/s12272-011-0118-z (2011).
    • (2011) Arch. Pharm. Res. , vol.34 , pp. 153-158
    • Park, K.1
  • 44
    • 35148864458 scopus 로고    scopus 로고
    • Renal clearance of quantum dots
    • Choi, H. S., et al. Renal clearance of quantum dots. Nat. Biotechnol. 25, 1165-70, doi:10.1038/nbt1340 (2007).
    • (2007) Nat. Biotechnol. , vol.25 , pp. 1165-1170
    • Choi, H.S.1
  • 45
    • 84885483569 scopus 로고    scopus 로고
    • Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
    • Tenzer, S., et al. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. Nat. Nanotechnol 8, 772-781, doi:10.1038/nnano.2013.181 (2013).
    • (2013) Nat. Nanotechnol , vol.8 , pp. 772-781
    • Tenzer, S.1
  • 46
    • 84867777335 scopus 로고    scopus 로고
    • Surface coatings shape the protein corona of SPIONs with relevance to their application in vivo
    • Jedlovszky-Hajdu, A., et al. Surface coatings shape the protein corona of SPIONs with relevance to their application in vivo. Langmuir 28, 14983-14991, doi:10.1021/la302446h (2012).
    • (2012) Langmuir , vol.28 , pp. 14983-14991
    • Jedlovszky-Hajdu, A.1
  • 47
    • 84901236286 scopus 로고    scopus 로고
    • Protein corona composition of superparamagnetic iron oxide nanoparticles with various physico-chemical properties and coatings
    • Sakulkhu, U., et al. Protein corona composition of superparamagnetic iron oxide nanoparticles with various physico-chemical properties and coatings. Sci. Rep 4, 5020, doi:10.1038/srep05020 (2014).
    • (2014) Sci. Rep , vol.4 , pp. 5020
    • Sakulkhu, U.1
  • 48
    • 84971330919 scopus 로고    scopus 로고
    • Size dependent effect of ZnO nanoparticles on endoplasmic reticulum stress signaling pathway in murine liver
    • Kuang, H., et al. Size dependent effect of ZnO nanoparticles on endoplasmic reticulum stress signaling pathway in murine liver. J. Hazard. Mater. 317, 119-126, doi:10.1016/j.jhazmat.2016.05.063 (2014).
    • (2014) J. Hazard. Mater. , vol.317 , pp. 119-126
    • Kuang, H.1
  • 49
    • 84862180734 scopus 로고    scopus 로고
    • Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel
    • Xu, L., et al. Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel. J. nanobiotechnol 10, 16, doi:10.1186/1477-3155-10-16 (2012).
    • (2012) J. Nanobiotechnol , vol.10 , pp. 16
    • Xu, L.1


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