AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 24, 2017, Pages E4822-E4831

  Schäper, Simon ^a   Steinchen, Wieland ^a   Krol, Elizaveta ^a   Altegoer, Florian ^a   Skotnicka, Dorota ^b   Søgaard Andersen, Lotte ^b   Bange, Gert ^a   Becker, Anke ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b MAX PLANCK INSTITUTE FOR TERRESTRIAL MICROBIOLOGY   (Germany)

Author keywords

C di GMP; Extracellular polysaccharide; PilZ; Sinorhizobium meliloti; Transcription factor

Indexed keywords

ARAC PROTEIN; CYCLIC GMP; HELIX LOOP HELIX PROTEIN; HOMODIMER; POLYSACCHARIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CUXR; UNCLASSIFIED DRUG; BACTERIAL POLYSACCHARIDE; BACTERIAL PROTEIN; BIS(3',5')-CYCLIC DIGUANYLIC ACID; PROTEIN BINDING; TRANSACTIVATOR PROTEIN;

ALPHAPROTEOBACTERIA; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; GENE CLUSTER; GENETIC TRANSCRIPTION; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SINORHIZOBIUM MELILOTI; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMISTRY; CONSERVED SEQUENCE; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN QUATERNARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ARAC TRANSCRIPTION FACTOR; BACTERIAL PROTEINS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYCLIC GMP; MODELS, MOLECULAR; POLYSACCHARIDES, BACTERIAL; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN DOMAINS; PROTEIN STRUCTURE, QUATERNARY; SINORHIZOBIUM MELILOTI; TRANS-ACTIVATORS;

EID: 85020701749     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1702435114     Document Type: Article

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