The Use of Mouse Asthma Models to Successfully Discover and Develop Novel Drugs

International Archives of Allergy and Immunology

Volumn 173, Issue 2, 2017, Pages 61-70

  Epstein, Michelle M ^a   Tilp, Cornelia ^b   Erb, Klaus J ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Animal models; Anti asthma drugs; Asthma therapy; Murine asthma models; Respiratory diseases

Indexed keywords

BIOLOGICAL MARKER; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; INTERLEUKIN 17; INTERLEUKIN 4; OVALBUMIN; ANTIASTHMATIC AGENT;

AIRWAY; ASTHMA; B LYMPHOCYTE; CARTILAGE; DISEASE EXACERBATION; DRUG DEVELOPMENT; ENVIRONMENT; EOSINOPHILIA; EXPERIMENTAL MODEL; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOCOMPETENT CELL; LUNG INFECTION; MAST CELL DEGRANULATION; MOUSE MODEL; MUSCLE HYPERTROPHY; NEUTROPHIL COUNT; NONHUMAN; PHENOTYPE; PNEUMONIA; POLLEN; PREDICTIVE VALUE; PRIORITY JOURNAL; REVIEW; RHINOVIRUS; SEX DIFFERENCE; SMOKING; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; DISEASE MODEL; MOUSE;

ANIMALS; ANTI-ASTHMATIC AGENTS; ASTHMA; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; HUMANS; MICE;

EID: 85020419923     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000473699     Document Type: Review

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