The microbiome and development of allergic disease

Current Opinion in Allergy and Clinical Immunology

Volumn 16, Issue 2, 2016, Pages 165-171

  Lynch, Susan V ^a   Boushey, Homer A ^b  

^a Division of Gastroenterology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

asthma; atopy; immune function; microbiome

Indexed keywords

ALLERGIC ASTHMA; ALLERGY; ATOPY; BRONCHIAL MICROBIOTA; CHILD; COMMENSAL; DISEASE ASSOCIATION; DISEASE COURSE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EVOLUTION; HUMAN; HYGIENE HYPOTHESIS; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INTESTINE FLORA; MICROBIAL COLONIZATION; MICROBIOME; NONHUMAN; PREVALENCE; PRIMARY PREVENTION; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; REVIEW; VIRUS INFECTION; WHEEZING; ADVERSE EFFECTS; ANIMAL; ASTHMA; BIOLOGICAL THERAPY; GENOTYPE ENVIRONMENT INTERACTION; HYPERSENSITIVITY; IMMUNE SYSTEM; INFANT; INTESTINE; MICROBIOLOGY; MICROFLORA; MOUSE; RESPIRATORY SYSTEM;

ANIMALS; ASTHMA; BIOLOGICAL THERAPY; ENVIRONMENTAL EXPOSURE; GENE-ENVIRONMENT INTERACTION; HUMANS; HYPERSENSITIVITY; IMMUNE SYSTEM; IMMUNE TOLERANCE; INFANT; INTESTINES; MICE; MICROBIOTA; RESPIRATORY SYSTEM;

EID: 84960077632     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0000000000000255     Document Type: Review

References (56)

1. Jackson DJ, Hartert TV, Martinez FD, et al. Asthma: NHLBI workshop on the primary prevention of chronic lung diseases. Ann Am Thorac Soc 2014; 11 (Suppl 3):S139-S145.
2. Bousquet J, Gern JE, Martinez FD, et al. Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop. J Allergy Clin Immunol 2014; 133:1535-1546.
3. Eder W, Ege MJ, von Mutius E. The asthma epidemic. N Engl J Med 2006; 355:2226-2235.
4. Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004; 59:469-478.
5. Newacheck PW, Halfon N. Prevalence, impact, and trends in childhood disability due to asthma. Arch Pediatr Adolesc Med 2000; 154:287-293.
6. Sears MR, Greene JM, Willan AR, et al. A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med 2003; 349:1414-1422.
7. Arshad SH, Tariq SM, Matthews S, Hakim E. Sensitization to common allergens and its association with allergic disorders at age 4 years: A whole population birth cohort study. Pediatrics 2001; 108:E33.
8. Gern JE. Promising candidates for allergy prevention. J Allergy Clin Immunol 2015; 136:23-28.
9. Platts-Mills TA. The allergy epidemics: 1870-2010. J Allergy Clin Immunol 2015; 136:3-13.
10. Pearce N, Ait-Khaled N, Beasley R, et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2007; 62:758-766.
11. Beasley R, Semprini A, Mitchell EA. Risk factors for asthma: is prevention possible? Lancet 2015; 386:1075-1085.
12. Crain EF, Weiss KB, Bijur PE, et al. An estimate of the prevalence of asthma and wheezing among inner-city children. Pediatrics 1994; 94:356-362.
13. Weiss KB, Gergen PJ, Crain EF. Inner-city asthma. The epidemiology of an emerging US public health concern. Chest 1992; 101:362S-367S.
14. Ober C, Yao TC. The genetics of asthma and allergic disease: A 21st century perspective. Immunol Rev 2011; 242:10-30.
15. Strachan DP. Hay fever, hygiene, and household size. BMJ 1989; 299:1259-1260.
16. Strachan DP. Family size, infection and atopy: The first decade of the hygiene hypothesis. Thorax 2000; 55 (Suppl 1):S2-S10.
17. Genuneit J. Exposure to farming environments in childhood and asthma and wheeze in rural populations: A systematic review with meta-Analysis. Pediatr Allergy Immunol 2012; 23:509-518.
18. Riedler J, Braun-Fahrlander C, Eder W, et al. Exposure to farming in early life and development of asthma and allergy: A cross-sectional survey. Lancet 2001; 358:1129-1133.
19. Fall T, Lundholm C, Ortqvist AK, et al. Early exposure to dogs and farm animals and the risk of childhood asthma. JAMA Pediatr 2015; 169: e153219.
20. Ownby DR, Johnson CC, Peterson EL. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA 2002; 288:963-972.
21. Braun-Fahrlander C, Riedler J, Herz U, et al. Environmental exposure to endotoxin and its relation to asthma in school-Age children. N Engl J Med 2002; 347:869-877.
22. Schuijs MJ, Willart MA, Vergote K, et al. Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells. Science 2015; 349:1106-1110.
23. Bager P, Melbye M, Rostgaard K, et al. Mode of delivery and risk of allergic rhinitis and asthma. J Allergy Clin Immunol 2003; 111:51-56.
24. Silvers KM, Frampton CM, Wickens K, et al. Breastfeeding protects against current asthma up to 6 years of age. J Pediatr 2012; 160:991-996; e991.
25. Waser M, Michels KB, Bieli C, et al. Inverse association of farm milk consumption with asthma and allergy in rural and suburban populations across Europe. Clin Exp Allergy 2007; 37:661-670.
26. Penders J, Kummeling I, Thijs C. Infant antibiotic use and wheeze and asthma risk: A systematic review and meta-Analysis. Eur Respir J 2011; 38:295-302.
27. Tariq SM, Matthews SM, Hakim EA, et al. The prevalence of and risk factors for atopy in early childhood: A whole population birth cohort study. J Allergy Clin Immunol 1998; 101:587-593.
28. von Mutius E, Martinez FD, Fritzsch C, et al. Prevalence of asthma and atopy in two areas of West and East Germany. Am J Respir Crit Care Med 1994; 149:358-364.
29. Rook GA. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Darwinian medicine and the hygiene or old friends hypothesis. Clin Exp Immunol 2010; 160:70-79.
30. Sepp E, Julge K, Vasar M, et al. Intestinal microflora of Estonian and Swedish infants. Acta Paediatr 1997; 86:956-961.
31. Bjorksten B, Naaber P, Sepp E, Mikelsaar M. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin Exp Allergy 1999; 29:342-346.
32. Bjorksten B, Sepp E, Julge K, et al. Allergy development and the intestinal microflora during the first year of life. J Allergy Clin Immunol 2001; 108:516-520.
33. Kalliomaki M, Kirjavainen P, Eerola E, et al. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J Allergy Clin Immunol 2001; 107:129-134.
34. Kusel MM, de Klerk NH, Kebadze T, et al. Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma. J Allergy Clin Immunol 2007; 119:1105-1110.
35. Lemanske RF Jr. The childhood origins of asthma (COAST) study. Pediatr Allergy Immunol 2002; 13 (Suppl 15):38-43.
36. Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 2009; 9:313-323.
37. Macpherson AJ, Harris NL. Interactions between commensal intestinal bacteria and the immune system. Nat Rev Immunol 2004; 4:478-485.
38. Smith K, McCoy KD, Macpherson AJ. Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota. Semin Immunol 2007; 19:59-69.
39. Atarashi K, Honda K. Microbiota in autoimmunity and tolerance. Curr Opin Immunol 2011; 23:761-768.
40. Ochoa-Reparaz J, Mielcarz DW, Ditrio LE, et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J Immunol 2010; 185:4101-4108.
41. Josefowicz SZ, Niec RE, Kim HY, et al. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 2012; 482:395-399.
42. Douwes J, Cheng S, Travier N, et al. Farm exposure in utero may protect against asthma, hay fever and eczema. Eur Respir J 2008; 32:603-611.
43. Aagaard K, Ma J, Antony KM, et al. The placenta harbors a unique microbiome. Sci Transl Med 2014; 6:237ra265.
44. Conrad ML, Ferstl R, Teich R, et al. Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78. J Exp Med 2009; 206:2869-2877.
45. Arrieta MC, Stiemsma LT, Dimitriu PA, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med 2015; 7:307ra152.
46. Dominguez-Bello MG, Costello EK, Contreras M, et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci U S A 2010; 107:11971-11975.
47. Renz-Polster H, David MR, Buist AS, et al. Caesarean section delivery and the risk of allergic disorders in childhood. Clin Exp Allergy 2005; 35:1466-1472.
48. Fujimura KE, Johnson CC, Ownby DR, et al. Mans best friend? The effect of pet ownership on house dust microbial communities. J Allergy Clin Immunol 2010; 126:410-412.
49. Bush RK, Portnoy JM. The role and abatement of fungal allergens in allergic diseases. J Allergy Clin Immunol 2001; 107:S430-440.
50. Gravesen S. Fungi as a cause of allergic disease. Allergy 1979; 34:135-154.
51. Kurup VP, Shen HD, Banerjee B. Respiratory fungal allergy. Microbes Infect 2000; 2:1101-1110.
52. Lynch SV, Wood RA, Boushey H, et al. Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol 2014; 134:593-601.
53. Fujimura KE, Demoor T, Rauch M, et al. House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection. Proc Natl Acad Sci U S A 2014; 111:805-810.
54. Fujimura KE, Lynch SV. Microbiota in allergy and asthma and the emerging relationship with the gut microbiome. Cell Host Microbe 2015; 17:592-602.
55. Trompette A, Gollwitzer ES, Yadava K, et al. Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis. Nat Med 2014; 20:159-166.
56. Holt PG. The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage. J Allergy Clin Immunol 2015; 136:15-22.