Hemoglobin inhibits albumin uptake by proximal tubule cells: Implications for sickle cell disease

American Journal of Physiology - Cell Physiology

Volumn 312, Issue 6, 2017, Pages C733-C740

  Eshbach, Megan L ^a   Kaur, Amandeep ^a   Rbaibi, Youssef ^a   Tejero, Jesús ^a   Weisz, Ora A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Megalin; Proteinuria; Proximal tubule; Sickle cell disease; Vitamin D

Indexed keywords

ALBUMIN; CUBILIN; HAPTOGLOBIN; HEME; HEME OXYGENASE 1; HEMOGLOBIN; HEMOGLOBIN A; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN BETA CHAIN; HEMOGLOBIN GAMMA CHAIN; HEMOGLOBIN H; HEMOGLOBIN S; HUMAN ALBUMIN; MEGALIN; HP PROTEIN, HUMAN; LIGAND; PROTEIN BINDING; SERUM ALBUMIN;

ADULT; ANIMAL CELL; ARTICLE; BINDING SITE; COMPARATIVE STUDY; CONTROLLED STUDY; DIDELPHIS VIRGINIANA; ENDOCYTOSIS; FEMALE; HEMOLYSIS; HUMAN; HUMAN CELL; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SICKLE CELL ANEMIA; ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; CELL LINE; CHEMISTRY; CYTOLOGY; GENETICS; METABOLISM; OPOSSUM; OXIDATION REDUCTION REACTION; PATHOLOGY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRANSFORMED CELL LINE;

AMINO ACID SEQUENCE; ANEMIA, SICKLE CELL; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; CELL LINE, TRANSFORMED; FEMALE; HAPTOGLOBINS; HEME; HEMOGLOBINS; HEMOLYSIS; HUMANS; KIDNEY TUBULES, PROXIMAL; LIGANDS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2; MALE; OPOSSUMS; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SERUM ALBUMIN;

EID: 85020382596     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00021.2017     Document Type: Article

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