Free actin impairs macrophage bacterial defenses via scavenger receptor MARCO interaction with reversal by plasma gelsolin

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 312, Issue 6, 2017, Pages L1018-L1028

  Ordija, Christine M ^a   Chiou, Terry Ting Yu ^a,b   Yang, Zhiping ^a   Deloid, Glen M ^a   De Oliveira Valdo, Melina ^a   Wang, Zhi ^a   Bedugnis, Alice ^a   Noah, Terry L ^c   Jones, Samuel ^c   Koziel, Henry ^d   Kobzik, Lester ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Actin; Alveolar macrophages; Plasma gelsolin; Scavenger receptors

Indexed keywords

ACTIN; BETA ACTIN; BOVINE SERUM ALBUMIN; FREE ACTIN; PLASMA GELSOLIN; PLASMA PROTEIN; SCAVENGER RECEPTOR; SCAVENGER RECEPTOR MARCO; UNCLASSIFIED DRUG; GELSOLIN; IMMUNOGLOBULIN RECEPTOR; MARCO PROTEIN, MOUSE; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BRONCHOALVEOLAR LAVAGE FLUID; CONTROLLED STUDY; ESCHERICHIA COLI; EXPERIMENTAL INFLUENZA; EXPERIMENTAL LUNG INJURY; EXTRACELLULAR SPACE; FEMALE; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG BURN; LUNG LAVAGE; MACROPHAGE CELL LINE; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; WESTERN BLOTTING; ANIMAL; BACTERIUM; BLOOD; C57BL MOUSE; IMMUNOLOGY; LUNG INJURY; MALE; METABOLISM; MICROBIOLOGY; PATHOLOGY;

ACTINS; ANIMALS; BACTERIA; FEMALE; GELSOLIN; HUMANS; LUNG INJURY; MACROPHAGES, ALVEOLAR; MALE; MICE, INBRED C57BL; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, SCAVENGER;

EID: 85020249513     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00067.2017     Document Type: Article

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