Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target

eLife

Volumn 3, Issue , 2014, Pages

  Yang, Zhiping ^a   Huang, Yuh Chin T ^a   Koziel, Henry ^a   de Crom, Rini ^a   Ruetten, Hartmut ^a   Wohlfart, Paulus ^a   Thomsen, Reimar W ^a   Kahlert, Johnny A ^a   Sørensen, Henrik Toft ^a   Jozefowski, Szczepan ^a   Colby, Amy ^a   Kobzik, Lester ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

bacteria; gender; human; human biology; immunology; innate immunity; macrophages; medicine; mouse; nitric oxide; pneumonia

Indexed keywords

1,3 BENZODIOXOLE DERIVATIVE; 2,2-DIFLUOROBENZO(1,3)DIOXOLE-5-CARBOXYLIC ACID INDAN-2-YLAMIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTROGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDAN DERIVATIVE;

ADOLESCENT; ADULT; AGED; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; DRUG EFFECTS; ENZYMOLOGY; FEMALE; HOSPITALIZATION; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MALE; METABOLISM; MICROBIAL VIABILITY; MIDDLE AGED; MOLECULARLY TARGETED THERAPY; ODDS RATIO; PATHOLOGY; PHAGOCYTOSIS; PNEUMONIA, PNEUMOCOCCAL; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BENZODIOXOLES; CASE-CONTROL STUDIES; ESTROGENS; FEMALE; HOSPITALIZATION; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNITY, INNATE; INDANS; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MALE; MICE, INBRED C57BL; MICROBIAL VIABILITY; MIDDLE AGED; MOLECULAR TARGETED THERAPY; NITRIC OXIDE SYNTHASE TYPE III; ODDS RATIO; PHAGOCYTOSIS; PNEUMONIA, PNEUMOCOCCAL; YOUNG ADULT;

EID: 84936137320     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.03711     Document Type: Article

References (0)