Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 22, 2017, Pages E4462-E4471

  Tobe, Brian T D ^a,b,c   Crain, Andrew M ^a,b   Winquist, Alicia M ^a,b   Calabrese, Barbara ^b,d   Makihara, Hiroko ^e   Zhao, Wen Ning ^f   Lalonde, Jasmin ^f   Nakamura, Haruko ^e   Konopaske, Glenn ^g,h,i   Sidor, Michelle ^j   Pernia, Cameron D ^a,b   Yamashita, Naoya ^e   Wada, Moyuka ^e   Inoue, Yuuka ^e   Nakamura, Fumio ^e   Sheridan, Steven D ^f   Logan, Ryan W ^j   Brandel, Michael ^a,b   Wu, Dongmei ^a   Hunsberger, Joshua ^a   Dorsett, Laurel ^a,b   Duerr, Cordulla ^a,b   Basa, Ranor C B ^l   McCarthy, Michael J ^c,m   Udeshi, Namrata D ⁿ   Mertins, Philipp ⁿ   Carr, Steven A ⁿ   Rouleau, Guy A ^o   Mastrangelo, Lina ^a,b   Li, Jianxue ^p   Gutierrez, Gustavo J ^a,q   Brill, Laurence M ^a   Venizelos, Nikolaos ^r   Chen, Guang ^s   Nye, Jeffrey S ^s   Manji, Husseini ^s   Price, Jeffrey H ^a,l   McClungk, Colleen A ^j   Akiskal, Hagop S ^m   Alda, Martin ^m   Chuang, De Maw M ^k   Coyle, Joseph T ^g,h   Liua, Yang ^a   Teng, Yang D ^h   Ohshima, Toshio ^t,u   Mikoshiba, Katsuhiko ^t,u   Sidman, Richard L ^p   Halpain, Shelley ^b,d   Haggarty, Stephen J ^f   Goshima, Yoshio ^e   Snyder, Evan Y ^a,b,v   more..

^a BURNHAM INSTITUTE   (United States)

^b SANFORD CONSORTIUM FOR REGENERATIVE MEDICINE   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^d NEUROBIOLOGY SECTION   (United States)

^e YOKOHAMA CITY UNIVERSITY   (Japan)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g MCLEAN HOSPITAL   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^k NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^l VALA SCIENCES INC   (United States)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^o DALHOUSIE UNIVERSITY   (Canada)

^p BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^q VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^r ÖREBRO UNIVERSITY   (Sweden)

^s JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^t WASEDA UNIVERSITY   (Japan)

^u RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^v UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

more..

Author keywords

CRMP2; Dendrites; Posttranslational modification; Proteomics; Psychiatric disease modeling

Indexed keywords

COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; LITHIUM; CALCIUM; COLLAPSIN RESPONSE MEDIATOR PROTEIN-2; NERVE PROTEIN; SIGNAL PEPTIDE;

ANIMAL TISSUE; ARTICLE; BIPOLAR DISORDER; CYTOSKELETON; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; MAJOR DEPRESSION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; ANIMAL; BIOLOGICAL MODEL; BRAIN CHEMISTRY; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; PROTEOMICS;

ANIMALS; BIPOLAR DISORDER; BRAIN CHEMISTRY; CALCIUM; CELLS, CULTURED; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LITHIUM; MICE; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS;

EID: 85020051123     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1700111114     Document Type: Article

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