Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia

Journal of the American Medical Directors Association

Volumn 18, Issue 7, 2017, Pages 637.e1-637.e11

  Kneppers, Anita E M ^a   Langen, Ramon C J ^a   Gosker, Harry R ^a   Verdijk, Lex B ^a   Cebron Lipovec, Nanca ^b   Leermakers, Pieter A ^a   Kelders, Marco C J M ^a   de Theije, Chiel C ^a   Omersa, Daniel ^c   Lainscak, Mitja ^d,e   Schols, Annemie M W J ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b University Clinic of Pulmonary and Allergic Diseases Golnik   (Slovenia)

^c NATIONAL INSTITUTE OF PUBLIC HEALTH   (Slovenia)

^d General Hospital Celje   (Slovenia)

^e UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Muscular atrophy; myogenic differentiation; protein biosynthesis; proteolysis

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INITIATION FACTOR 4E BINDING PROTEIN 1; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 1; MUSCLE PROTEIN; MYOSTATIN; SEQUESTOSOME 1; TRANSCRIPTION FACTOR FKHR;

ADULT; ARTICLE; AUTOPHAGY; BODY COMPOSITION; BODY MASS; BONE DENSITOMETRY; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; HUMAN TISSUE; ICD-10-CM; LYSOSOME; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MUSCLE BIOPSY; MUSCLE DEVELOPMENT; MUSCLE MASS; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOPENIA; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE; AGED; COMPLICATION; METABOLISM; MUSCLE ATROPHY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; SARCOPENIA; SIGNAL TRANSDUCTION;

EID: 85020030738     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2017.04.016     Document Type: Article

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