메뉴 건너뛰기




Volumn 9, Issue 6, 2006, Pages 672-676

Eat the meat or feed the meat: Protein turnover in remodeling muscle

Author keywords

Exercise; Nutrition; Protein degradation; Protein synthesis

Indexed keywords

AMINO ACID; MUSCLE PROTEIN;

EID: 33750286069     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/01.mco.0000247471.64532.7d     Document Type: Review
Times cited : (8)

References (36)
  • 1
    • 0022831821 scopus 로고
    • Determinants of 24-h energy expenditure in man. Methods and results using a respiratory chamber
    • Ravussin E, Lillioja S, Anderson TE, et al. Determinants of 24-h energy expenditure in man. Methods and results using a respiratory chamber. J Clin Invest 1986; 78:1568-1578.
    • (1986) J Clin Invest , vol.78 , pp. 1568-1578
    • Ravussin, E.1    Lillioja, S.2    Anderson, T.E.3
  • 2
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
    • DeFronzo RA, Gunnarsson R, Bjorkman O, et al. Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest 1985; 76:149-155.
    • (1985) J Clin Invest , vol.76 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Bjorkman, O.3
  • 3
    • 0020464729 scopus 로고
    • Muscle protein synthesis measured by stable isotope techniques in man: The effects of feeding and fasting
    • (Lond)
    • Rennie MJ, Edwards RH, Halliday D, et al. Muscle protein synthesis measured by stable isotope techniques in man: the effects of feeding and fasting. Clin Sci (Lond) 1982; 63:519-523.
    • (1982) Clin Sci , vol.63 , pp. 519-523
    • Rennie, M.J.1    Edwards, R.H.2    Halliday, D.3
  • 4
    • 0024567234 scopus 로고
    • Increase in anterior tibialis muscle protein synthesis in healthy man during mixed amino acid infusion: Studies of incorporation of [1-13C]leucine
    • (Lond)
    • Bennet WM, Connacher AA, Scrimgeour CM, et al. Increase in anterior tibialis muscle protein synthesis in healthy man during mixed amino acid infusion: studies of incorporation of [1-13C]leucine. Clin Sci (Lond) 1989; 76:447-454.
    • (1989) Clin Sci , vol.76 , pp. 447-454
    • Bennet, W.M.1    Connacher, A.A.2    Scrimgeour, C.M.3
  • 5
    • 0031831344 scopus 로고    scopus 로고
    • Effects of flooding amino acids on incorporation of labeled amino acids into human muscle protein
    • Smith K, Reynolds N, Downie S, et al. Effects of flooding amino acids on incorporation of labeled amino acids into human muscle protein. Am J Physiol 1998; 275:E73-E78.
    • (1998) Am J Physiol , vol.275
    • Smith, K.1    Reynolds, N.2    Downie, S.3
  • 6
    • 0025328669 scopus 로고
    • Influence of leucine infusion on intracellular amino acids in humans
    • Alvestrand A, Hagenfeldt L, Merli M, et al. Influence of leucine infusion on intracellular amino acids in humans. Eur J Clin Invest 1990; 20:293-298.
    • (1990) Eur J Clin Invest , vol.20 , pp. 293-298
    • Alvestrand, A.1    Hagenfeldt, L.2    Merli, M.3
  • 7
    • 0142062041 scopus 로고    scopus 로고
    • Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: A dose-response study
    • Bohe J, Low A, Wolfe RR, et al. Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study. J Physiol 2003; 552:315-324.
    • (2003) J Physiol , vol.552 , pp. 315-324
    • Bohe, J.1    Low, A.2    Wolfe, R.R.3
  • 8
    • 22144465152 scopus 로고    scopus 로고
    • Body maintenance and repair: How food and exercise keep the musculoskeletal system in good shape
    • Rennie MJ. Body maintenance and repair: how food and exercise keep the musculoskeletal system in good shape. Exp Physiol 2005; 90:427-436.
    • (2005) Exp Physiol , vol.90 , pp. 427-436
    • Rennie, M.J.1
  • 9
  • 10
    • 0033949496 scopus 로고    scopus 로고
    • Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate
    • van Loon LJ, Saris WH, Verhagen H, et al. Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate. Am J Clin Nutr 2000; 72:96-105.
    • (2000) Am J Clin Nutr , vol.72 , pp. 96-105
    • Loon, L.J.1    Saris, W.H.2    Verhagen, H.3
  • 11
    • 0028837394 scopus 로고
    • Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle
    • Biolo G, Declan Fleming RY, Wolfe RR. Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle. J Clin Invest 1995; 95:811-819.
    • (1995) J Clin Invest , vol.95 , pp. 811-819
    • Biolo, G.1    Declan Fleming, R.Y.2    Wolfe, R.R.3
  • 12
    • 14644444464 scopus 로고    scopus 로고
    • Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
    • Cuthbertson D, Smith K, Babraj J, et al. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J 2005; 19:422-424. A report showing that exogenous amino acids stimulate protein synthesis independent of insulin, conserved basal rates of protein synthesis in elderly but decreased sensitivity and responsiveness to exogenous amino acids possibly linked to components of anabolic signaling pathways.
    • (2005) FASEB J , vol.19 , pp. 422-424
    • Cuthbertson, D.1    Smith, K.2    Babraj, J.3
  • 13
    • 0142116163 scopus 로고    scopus 로고
    • No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise
    • Louis M, Poortmans JR, Francaux M, et al. No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise. Am J Physiol Endocrinol Metab 2003; 285:E1089-E1094.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Louis, M.1    Poortmans, J.R.2    Francaux, M.3
  • 14
    • 0035871128 scopus 로고    scopus 로고
    • Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids
    • Bohe J, Low JF, Wolfe RR, et al. Latency and duration of stimulation of human muscle protein synthesis during continuous infusion of amino acids. J Physiol 2001; 532:575-579.
    • (2001) J Physiol , vol.532 , pp. 575-579
    • Bohe, J.1    Low, J.F.2    Wolfe, R.R.3
  • 15
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock KL, Gramm C, Rothstein L, et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 1994; 78:761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3
  • 16
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges D, Zwickl P, Baumeister W. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 1999; 68:1015-1068.
    • (1999) Annu Rev Biochem , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 17
    • 0032947267 scopus 로고    scopus 로고
    • Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states
    • Lecker SH, Solomon V, Mitch WE, et al. Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. J Nutr 1999; 129:227S-237S.
    • (1999) J Nutr , vol.129
    • Lecker, S.H.1    Solomon, V.2    Mitch, W.E.3
  • 18
    • 0029022262 scopus 로고
    • Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation
    • Wing SS, Haas AL, Goldberg AL. Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation. Biochem J 1995; 307 (Pt 3):639-645.
    • (1995) Biochem J , vol.307 , Issue.PART 3 , pp. 639-645
    • Wing, S.S.1    Haas, A.L.2    Goldberg, A.L.3
  • 19
    • 0035350530 scopus 로고    scopus 로고
    • What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?
    • Jagoe RT, Goldberg AL. What do we really know about the ubiquitin-proteasome pathway in muscle atrophy? Curr Opin Clin Nutr Metab Care 2001; 4:183-190.
    • (2001) Curr Opin Clin Nutr Metab Care , vol.4 , pp. 183-190
    • Jagoe, R.T.1    Goldberg, A.L.2
  • 20
    • 29344464782 scopus 로고    scopus 로고
    • Protein synthesis upon acute nutrient restriction relies on proteasome function
    • Vabulas RM, Hartl FU. Protein synthesis upon acute nutrient restriction relies on proteasome function. Science 2005; 310:1960-1963. A report showing that amino acids for de-novo protein synthesis are derived from the degradation of preexisting proteins, whereas nascent and newly formed polypeptides remained largely protected from proteolysis. Proteasome inhibition during nutrient deprivation caused rapid amino acid depletion and marked impairment of translation, identifying the ubiquitin-proteosome pathway as a critical player with respect to cell survival during starvation.
    • (2005) Science , vol.310 , pp. 1960-1963
    • Vabulas, R.M.1    Hartl, F.U.2
  • 21
    • 0034643336 scopus 로고    scopus 로고
    • Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
    • Schubert U, Anton LC, Gibbs J, et al. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 2000; 404:770-774.
    • (2000) Nature , vol.404 , pp. 770-774
    • Schubert, U.1    Anton, L.C.2    Gibbs, J.3
  • 22
    • 2942733632 scopus 로고    scopus 로고
    • Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- And exercise-induced signalling
    • Bolster DR, Jefferson LS, Kimball SR. Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- and exercise-induced signalling. Proc Nutr Soc 2004; 63:351-356.
    • (2004) Proc Nutr Soc , vol.63 , pp. 351-356
    • Bolster, D.R.1    Jefferson, L.S.2    Kimball, S.R.3
  • 23
    • 20644440418 scopus 로고    scopus 로고
    • The kinase domain of titin controls muscle gene expression and protein turnover
    • Lange S, Xiang F, Yakovenko A, et al. The kinase domain of titin controls muscle gene expression and protein turnover. Science 2005; 308:1599-1603. A report showing the importance of the sensing of mechanical load by titin with respect to regulating protein turnover in muscle.
    • (2005) Science , vol.308 , pp. 1599-1603
    • Lange, S.1    Xiang, F.2    Yakovenko, A.3
  • 24
    • 18144386162 scopus 로고    scopus 로고
    • Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation
    • Atherton PJ, Babraj J, Smith K, et al. Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. FASEB J 2005; 19:786-788. The first report identifying distinct signaling pathways for resistance versus endurance exercise.
    • (2005) FASEB J , vol.19 , pp. 786-788
    • Atherton, P.J.1    Babraj, J.2    Smith, K.3
  • 25
    • 30744439347 scopus 로고    scopus 로고
    • Early signaling responses to divergent exercise stimuli in skeletal muscle from well trained humans
    • Coffey VG, Zhong Z, Shield A, et al. Early signaling responses to divergent exercise stimuli in skeletal muscle from well trained humans. FASEB J 2006; 20:190-192. A report examining the effect of training history on the signaling responsiveness to resistance and endurance exercise.
    • (2006) FASEB J , vol.20 , pp. 190-192
    • Coffey, V.G.1    Zhong, Z.2    Shield, A.3
  • 26
    • 10644253597 scopus 로고    scopus 로고
    • Intracellular signaling specificity in response to uniaxial vs. multiaxial stretch: Implications for mechanotransduction
    • Hornberger TA, Armstrong DD, Koh TJ, et al. Intracellular signaling specificity in response to uniaxial vs. multiaxial stretch: implications for mechanotransduction. Am J Physiol Cell Physiol 2005; 288:C185-C194. Studies in cultured muscle cells showing that anabolic responses in muscle cells are sensitive to the direction of strain.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Hornberger, T.A.1    Armstrong, D.D.2    Koh, T.J.3
  • 27
    • 33646083955 scopus 로고    scopus 로고
    • Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exercise
    • Cuthbertson DJ, Babraj J, Smith K, et al. Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exercise. Am J Physiol Endocrinol Metab 2006; 290:E731-E738. A human study examining the effect of positive versus negative work on anabolic signaling pathways.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Cuthbertson, D.J.1    Babraj, J.2    Smith, K.3
  • 28
    • 19444386124 scopus 로고    scopus 로고
    • Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions
    • Moore DR, Phillips SM, Babraj JA, et al. Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions. Am J Physiol Endocrinol Metab 2005; 288:E1153-E1159. A report showing exercise mode-specific effects on both myofibrillar and extracellular matrix protein synthesis.
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Moore, D.R.1    Phillips, S.M.2    Babraj, J.A.3
  • 29
    • 33750371417 scopus 로고    scopus 로고
    • Maximal lengthening contractions increase p70S6 kinase phosphorylation in human skeletal muscle in the absence of nutritional supply
    • 11 July E-pub ahead of print
    • Eliasson J, Elfegoun T, Nilsson J, et al. Maximal lengthening contractions increase p70S6 kinase phosphorylation in human skeletal muscle in the absence of nutritional supply. Am J Physiol Endocrinol Metab, 11 July 2006. E-pub ahead of print. A report showing that activation of the anabolic signaling pathways upon lengthening exercise occurs without nutritional supply.
    • (2006) Am J Physiol Endocrinol Metab
    • Eliasson, J.1    Elfegoun, T.2    Nilsson, J.3
  • 30
    • 6944226810 scopus 로고    scopus 로고
    • Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass
    • Jones SW, Hill RJ, Krasney PA, et al. Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass. FASEB J 2004; 18:1025-1027.
    • (2004) FASEB J , vol.18 , pp. 1025-1027
    • Jones, S.W.1    Hill, R.J.2    Krasney, P.A.3
  • 31
    • 33644670831 scopus 로고    scopus 로고
    • Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis but independent of protein synthesis
    • Krawiec BJ, Frost RA, Vary TC, et al. Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis but independent of protein synthesis. Am J Physiol Endocrinol Metab 2005; 289:E969-E980.
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Krawiec, B.J.1    Frost, R.A.2    Vary, T.C.3
  • 32
    • 33745498417 scopus 로고    scopus 로고
    • TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism
    • Qi L, Heredia JE, Altarejos JY, et al. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science 2006; 312:1763-1766. An elegant work identifying a role for the ubiquitin-proteasome pathway in metabolic remodeling by the targeted degradation of fuel-sensing proteins next to the classically known routes of phosphorylation activation.
    • (2006) Science , vol.312 , pp. 1763-1766
    • Qi, L.1    Heredia, J.E.2    Altarejos, J.Y.3
  • 33
    • 0034802263 scopus 로고    scopus 로고
    • Cellular adaptation to repeated eccentric exercise-induced muscle damage
    • Stupka N, Tarnopolsky MA, Yardley NJ, et al. Cellular adaptation to repeated eccentric exercise-induced muscle damage. J Appl Physiol 2001; 91:1669-1678.
    • (2001) J Appl Physiol , vol.91 , pp. 1669-1678
    • Stupka, N.1    Tarnopolsky, M.A.2    Yardley, N.J.3
  • 34
    • 0344666783 scopus 로고    scopus 로고
    • Glucocorticoid receptor and ubiquitin expression after repeated eccentric exercise
    • Willoughby DS, Taylor M, Taylor L. Glucocorticoid receptor and ubiquitin expression after repeated eccentric exercise. Med Sci Sports Exerc 2003; 35:2023-2031.
    • (2003) Med Sci Sports Exerc , vol.35 , pp. 2023-2031
    • Willoughby, D.S.1    Taylor, M.2    Taylor, L.3
  • 35
    • 20844460131 scopus 로고    scopus 로고
    • Metabolic activity and collagen turnover in human tendon in response to physical activity
    • Kjaer M, Langberg H, Miller BF, et al. Metabolic activity and collagen turnover in human tendon in response to physical activity. J Musculoskelet Neuronal Interact 2005; 5:41-52. One of the few papers focusing on extracellular matrix remodeling upon exercise, which is of importance because muscle cell growth also requires extracellular matrix remodeling.
    • (2005) J Musculoskelet Neuronal Interact , vol.5 , pp. 41-52
    • Kjaer, M.1    Langberg, H.2    Miller, B.F.3
  • 36
    • 0036261245 scopus 로고    scopus 로고
    • Short-term effects of forced eccentric contractions on collagen synthesis and degradation in rat skeletal muscle
    • Koskinen SO, Ahtikoski AM, Komulainen J, et al. Short-term effects of forced eccentric contractions on collagen synthesis and degradation in rat skeletal muscle. Pflugers Arch 2002; 444:59-72.
    • (2002) Pflugers Arch , vol.444 , pp. 59-72
    • Koskinen, S.O.1    Ahtikoski, A.M.2    Komulainen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.