Oxidative stress, redox signaling pathways, and autophagy in cachectic muscles of male patients with advanced COPD and lung cancer

Free Radical Biology and Medicine

Volumn 79, Issue , 2015, Pages 91-108

  Puig Vilanova, Ester ^a,b   Rodriguez, Diego A ^a,b   Lloreta, Josep ^c   Ausin, Pilar ^a,b   Pascual Guardia, Sergio ^a,b   Broquetas, Joan ^a   Roca, Josep ^b,d   Gea, Joaquim ^a,b   Barreiro, Esther ^a,b  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Autophagy; COPD cachexia; Inflammation; Lung cancer cachexia; Muscle structure and ultrastructural abnormalities; Proteolysis and redox signaling pathways; Redox imbalance

Indexed keywords

ANTIOXIDANT; ATROGIN 1; BIOLOGICAL MARKER; CREATINE KINASE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGHT CHAIN 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCLE PROTEIN; MUSCLE RING FINGER 1 PROTEIN; MYOSTATIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; TRANSCRIPTION FACTOR FOXO; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADULT; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CACHEXIA; CELL FUNCTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; INFLAMMATION; LUNG CANCER; MALE; MITOCHONDRION; MUSCLE ATROPHY; MUSCLE CONTRACTILITY; MUSCLE DEVELOPMENT; MUSCLE FUNCTION; MUSCLE GROWTH; MUSCLE INJURY; MUSCULAR DYSTROPHY; OXIDATION; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN OXIDATION; REDOX BALANCE; SARCOMERE; SIGNAL TRANSDUCTION; UBIQUITINATION; VASTUS LATERALIS MUSCLE; AGED; CASE CONTROL STUDY; LUNG TUMOR; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; SKELETAL MUSCLE;

AGED; AUTOPHAGY; CACHEXIA; CASE-CONTROL STUDIES; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84919644370     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.11.006     Document Type: Article

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