Effects of Donor Breastmilk Feeding on Growth and Early Neurodevelopmental Outcomes in Preterm Infants: An Observational Study

Clinical Therapeutics

Volumn 39, Issue 6, 2017, Pages 1210-1220

  Madore, Laura S ^a,b   Bora, Samudragupta ^c,d   Erdei, Carmina ^a,c   Jumani, Tina ^a,e   Dengos, Allison R ^a,f   Sen, Sarbattama ^a,c  

^a TUFTS MEDICAL CENTER   (United States)

^b BAYSTATE MEDICAL CENTER   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e ALBANY MEDICAL CENTER   (United States)

^f ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

donor breastmilk; growth; neurodevelopment; preterm infants

Indexed keywords

APGAR SCORE; ARTICLE; ARTIFICIAL MILK; BAYLEY SCALES OF INFANT DEVELOPMENT; BIRTH WEIGHT; BODY HEIGHT; BRAIN INJURY; BREAST FEEDING; BREAST MILK; CHILD DEVELOPMENT; CHILD GROWTH; COGNITION; COHORT ANALYSIS; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE SEVERITY; DONOR BREAST MILK; FEMALE; GESTATIONAL AGE; HEAD CIRCUMFERENCE; HOUSEHOLD INCOME; HUMAN; INFANT; LANGUAGE; LENGTH OF STAY; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MOTOR PERFORMANCE; NECROTIZING ENTEROCOLITIS; NEONATAL INTENSIVE CARE UNIT; NERVE CELL DIFFERENTIATION; NEWBORN MORBIDITY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PATENT DUCTUS ARTERIOSUS; PERINATAL DRUG EXPOSURE; POSITIVE END EXPIRATORY PRESSURE; PREMATURITY; RETROLENTAL FIBROPLASIA; SMALL FOR DATE INFANT; SOCIOECONOMICS; WEIGHT GAIN; WEIGHT REDUCTION; NEWBORN;

BIRTH WEIGHT; CHILD DEVELOPMENT; COGNITION; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INTENSIVE CARE UNITS, NEONATAL; MALE; MILK, HUMAN; WEIGHT GAIN;

EID: 85019972765     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2017.05.341     Document Type: Article

References (40)

1. American Academy of Pediatrics, Section on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics 129 (2012), 827–841.
2. Hack, M., Young adult outcomes of very-low-birth-weight children. Semin Fetal Neonatal Med 11 (2006), 127–137.
3. Lucas, A., Morley, R., Cole, T.J., et al. Breast milk and subsequent intelligence quotient in children born preterm. Lancet 339 (1992), 261–264.
4. Vohr, B.R., Poindexter, B.B., Dusick, A.M., et al. Persistent beneficial effects of breast milk ingested in the neonatal intensive care unit on outcomes of extremely low birth weight infants at 30 months of age. Pediatrics 120 (2007), 953–959.
5. Sullivan, S., Schanler, R.J., Kim, J.H., et al. An exclusively human milk-based diet is associated with a lower rate of necrotizing enterocolitis than a diet of human milk and bovine milk-based products. J Pediatr 156 (2010), 562–567.
6. Jones, F., History of North American donor milk banking: one hundred years of progress. J Hum Lact 19 (2003), 313–318.
7. Kim, J.H., Unger, S., Human milk banking. Paediatr Child Health 15 (2010), 595–598.
8. Hagadorn, J.I., Brownell, E.A., Lussier, M.M., et al. Variability of criteria for pasteurized donor human milk use: a survey of US neonatal intensive care unit medical directors. JPEN J Parenter Enteral Nutr 40 (2016), 326–333.
9. Arslanoglu, S., Corpeleijn, W., Moro, G., et al., European Society for Paediatric Gastroenterology Hepatology and Nutrition Committee on Nutrition. Donor human milk for preterm infants: current evidence and research directions. J Pediatr Gastroenterol Nutr 57 (2013), 535–542.
10. Corpeleijn, W.E., de Waard, M., Christmann, V., et al. Effect of donor milk on severe infections and mortality in very low-birth-weight infants: the early nutrition study randomized clinical trial. JAMA Pediatr 170 (2016), 654–661.
11. O'Connor, D.L., Gibbins, S., Kiss, A., et al., Greater Toronto Area DoMINO Feeding Group. Effect of supplemental donor human milk compared with preterm formula on neurodevelopment of very low-birth-weight infants at 18 months: a randomized clinical trial. JAMA 316 (2016), 1897–1905.
12. Quigley, M., McGuire, W., Formula versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst Rev 4 (2014), 1–92.
13. Andersson, Y., Savman, K., Blackberg, L., Hernell, O., Pasteurization of mother's own milk reduces fat absorption and growth in preterm infants. Acta Paediatr 96 (2007), 1445–1449.
14. Montjaux-Régis, N., Cristini, C., Arnaud, C., et al. Improved growth of preterm infants receiving mother's own raw milk compared with pasteurized donor milk. Acta Paediatr 100 (2011), 1548–1554.
15. Colaizy, T.T., Carlson, S., Saftlas, A.F., Morriss, F.H. Jr., Growth in VLBW infants fed predominantly fortified maternal and donor human milk diets: a retrospective cohort study. BMC Pediatr, 12, 2012, 124.
16. Sisk, P.M., Lambeth, T.M., Rojas, M.A., et al. Necrotizing enterocolitis and growth in preterm infants fed predominantly maternal milk, pasteurized donor milk, or preterm formula: a retrospective study. Am J Perinatol, 2016 [Epub ahead of print].
17. Ehrenkranz, R.A., Dusick, A.M., Vohr, B.R., et al. Growth in the neonatal intensive care unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants. Pediatrics 117 (2006), 1253–1261.
18. Stephens, B.E., Walden, R.V., Gargus, R.A., et al. First-week protein and energy intakes are associated with 18-month developmental outcomes in extremely low birth weight infants. Pediatrics 123 (2009), 1337–1343.
19. Chan, S.H., Johnson, M.J., Leaf, A.A., Vollmer, B., Nutrition and neurodevelopmental outcomes in preterm infants: a systematic review. Acta Paediatr 105 (2016), 587–599.
20. Guidelines for the Establishment and Operation of a Donor Human Milk Bank. 2013, Human Milk Banking Association of North America, Fort Worth, TX.
21. Lechner, B.E., Vohr, B.R., Neurodevelopmental outcomes of preterm infants fed human milk: a systematic review. Clin Perinatol 44 (2017), 69–83.
22. Ewaschuk, J.B., Unger, S., O'Connor, D.L., et al. Effect of pasteurization on selected immune components of donated human breast milk. J Perinatol 31 (2011), 593–598.
23. Lawrence, R.A., Milk banking: The influence of storage procedures and subsequent processing on immunologic components of human milk. Adv Nutr Res 10 (2001), 389–404.
24. Vieira, A.A., Soares, F.V., Pimenta, H.P., et al. Analysis of the influence of pasteurization, freezing/thawing, and offer processes on human milk's macronutrient concentrations. Early Hum Dev 87 (2011), 577–580.
25. Wojcik, K.Y., Rechtman, D.J., Lee, M.L., et al. Macronutrient analysis of a nationwide sample of donor breast milk. J Am Diet Assoc 109 (2009), 137–140.
26. Radmacher, P.G., Lewis, S.L., Adamkin, D.H., Individualizing fortification of human milk using real time human milk analysis. J Neonatal Perinatal Med 6 (2013), 319–323.
27. Bauer, J., Gerss, J., Longitudinal analysis of macronutrients and minerals in human milk produced by mothers of preterm infants. Clin Nutr 30 (2011), 215–220.
28. de Halleux, V., Rigo, J., Variability in human milk composition: benefit of individualized fortification in very-low-birth-weight infants. Am J Clin Nutr 98 (2013), 529–535.
29. National Institute of Child Health and Human Development, Neonatal Research Network. Donor milk vs. formula in extremely low birth weight (ELBW) infants. Available at: https://clinicaltrials.gov/ct2/show/NCT01534481?term=donor+milk&rank=3. Accessed 03/15/2017.
30. Valentine, C.J., Morrow, G., Fernandez, S., et al. Docosahexaenoic acid and amino acid contents in pasteurized donor milk are low for preterm infants. J Pediatr 157 (2010), 906–910.
31. Baack, M.L., Norris, A.W., Yao, J., Colaizy, T., Long-chain polyunsaturated fatty acid levels in US donor human milk: meeting the needs of premature infants?. J Perinatol 32 (2012), 598–603.
32. Henderson, T.R., Fay, T.N., Hamosh, M., Effect of pasteurization on long-chain polyunsaturated fatty acid levels and enzyme activities of human milk. J Pediatr 132 (1998), 876–878.
33. Wardell, J.M., Wright, A.J., Bardsley, W.G., D'Souza, S.W., Bile salt-stimulated lipase and esterase activity in human milk after collection, storage, and heating: nutritional implications. Pediatr Res 18 (1984), 382–386.
34. Hernell, O., Human milk lipases III. Physiological implications of the bile salt stimulated lipase. Eur J Clin Invest 5 (1975), 267–272.
35. Silvestre, D., Miranda, M., Muriach, M., et al. Antioxidant capacity of human milk: effect of thermal conditions for the pasteurization. Acta Paediatr 97 (2008), 1070–1074.
36. Shim, S.Y., Kim, H.S., Oxidative stress and the antioxidant enzyme system in the developing brain. Korean J Pediatr 56 (2013), 107–111.
37. Wang, B., Sialic acid is an essential nutrient for brain development and cognition. Annu Rev Nutr 29 (2009), 177–222.
38. Marx, C., Bridge, R., Wolf, A.K., et al. Human milk oligosaccharide composition differs between donor milk and mother's own milk in the NICU. J Hum Lact 30 (2014), 54–61.
39. Keunen, K., van Elburg, R.M., van Bel, F., Benders, M.J., Impact of nutrition on brain development and its neuroprotective implications following preterm birth. Pediatr Res 77 (2015), 148–155.
40. Spencer-Smith, M.M., Spittle, A.J., Lee, K.J., et al. Bayley-III cognitive and language scales in preterm children. Pediatrics 135 (2015), 1258–1265.