Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

Nature Communications

Volumn 8, Issue , 2017, Pages

  Sapkota, Yadav ^a,b   Steinthorsdottir, Valgerdur ^c   Morris, Andrew P ^d,e   Fassbender, Amelie ^f   Rahmioglu, Nilufer ^e   De Vivo, Immaculata ^g,h   Buring, Julie E ^g,i   Zhang, Futao ^j   Edwards, Todd L ^k   Jones, Sarah ^k   Dorien, O ^f   Peterse, Daniëlle ^f   Rexrode, Kathryn M ^g,i   Ridker, Paul M ^g,i   Schork, Andrew J ^l,m   MacGregor, Stuart ^a   Martin, Nicholas G ^a   Becker, Christian M ⁿ   Adachi, Sosuke ^o   Yoshihara, Kosuke ^o   Enomoto, Takayuki ^o   Takahashi, Atsushi ^p   Kamatani, Yoichiro ^p   Matsuda, Koichi ^q   Kubo, Michiaki ^p   Thorleifsson, Gudmar ^c   Geirsson, Reynir T ^r,s   Thorsteinsdottir, Unnur ^c,s   Wallace, Leanne M ^a,j   Werge, Thomas M ^u,y,z   Thompson, Wesley K ^u,y,aa   Yang, Jian ^j   Velez Edwards, DIgna R ^k   Nyegaard, Mette ^t,u   Low, Siew Kee ^p   Zondervan, Krina T ^e,n   Missmer, Stacey A ^g,h   D'Hooghe, Thomas ^f,v   Montgomery, Grant W ^a,j   Chasman, Daniel I ^g,i   Stefansson, Kari ^c,s   Tung, Joyce Y ^w   Nyholt, Dale R ^a,x   more..

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c DECODE GENETICS   (Iceland)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

^j UNIVERSITY OF QUEENSLAND   (Australia)

^k VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^l UNIVERSITY OF CALIFORNIA   (United States)

^m Mental Health Center Glostrup   (Denmark)

ⁿ UNIVERSITY OF OXFORD   (United Kingdom)

^o NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^p Institute of Physical and Chemical Research   (Japan)

^q UNIVERSITY OF TOKYO   (Japan)

^r LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^s UNIVERSITY OF ICELAND   (Iceland)

^t AARHUS UNIVERSITY   (Denmark)

^u H LUNDBECK A S   (Denmark)

^v MERCK KGAA   (Germany)

^w Merck KGaA ^*  (United States)

^x QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^y Institute of Biological Psychiatry MHC Sct Hans Mental Health Services Copenhagen   (Denmark)

^z UNIVERSITY OF COPENHAGEN   (Denmark)

^aa UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CCDC170 PROTEIN; ESTROGEN RECEPTOR ALPHA; FIBRONECTIN; FIBRONECTIN 1; FOLLITROPIN BETA SUBUNIT; SEX HORMONE; SYNE1 PROTEIN; UNCLASSIFIED DRUG; ESTROGEN RECEPTOR ALPHA, HUMAN;

DISEASE INCIDENCE; FERTILITY; GENE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC MARKER; HORMONE; META-ANALYSIS; METABOLISM; RESEARCH WORK; SEX HORMONE;

ARTICLE; BIOINFORMATICS; CASE CONTROL STUDY; ENDOMETRIOSIS; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC RISK; GENETIC TRAIT; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HORMONE METABOLISM; HUMAN; MENDELIAN RANDOMIZATION ANALYSIS; META ANALYSIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; AGED; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; METABOLISM; MIDDLE AGED;

ADULT; AGED; ENDOMETRIOSIS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GONADAL STEROID HORMONES; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 85019935832     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms15539     Document Type: Article

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