Healthcare utilization and costs in ARDS survivors: a 1-year longitudinal national US multicenter study

Intensive Care Medicine

Volumn 43, Issue 7, 2017, Pages 980-991

  Ruhl, A Parker ^a,b   Huang, Minxuan ^b   Colantuoni, Elizabeth ^b,c   Karmarkar, Taruja ^c   Dinglas, Victor D ^b   Hopkins, Ramona O ^d,e,f   Needham, Dale M ^b  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d INTERMOUNTAIN MEDICAL CENTER   (United States)

^e INTERMOUNTAIN HEALTHCARE   (United States)

^f BRIGHAM YOUNG UNIVERSITY   (United States)

Author keywords

Cost; Critical illness; Healthcare; Patient readmission; Quality of life

Indexed keywords

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ANXIETY; ARTICLE; CARDIOVASCULAR DISEASE; COGNITION; COHORT ANALYSIS; DEPRESSION; DIABETES MELLITUS; FEMALE; FOLLOW UP; HEALTH CARE COST; HEALTH CARE UTILIZATION; HEALTH INSURANCE; HOSPITAL COST; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; LENGTH OF STAY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MIDDLE AGED; MULTICENTER STUDY; OUTPATIENT CARE; PHYSICAL ACTIVITY; PHYSIOTHERAPY; PNEUMONIA; QUALITY OF LIFE; SEPSIS; STRUCTURED INTERVIEW; SURVIVOR; CLINICAL TRIAL; CRITICAL CARE OUTCOME; ECONOMICS; INTENSIVE CARE UNIT; PATIENT ATTITUDE; PSYCHOLOGY; REHABILITATION CENTER; STATISTICS AND NUMERICAL DATA; UTILIZATION;

ADULT; CRITICAL CARE OUTCOMES; FEMALE; HOSPITAL COSTS; HUMANS; INTENSIVE CARE UNITS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PATIENT ACCEPTANCE OF HEALTH CARE; PATIENT READMISSION; QUALITY OF LIFE; REHABILITATION CENTERS; RESPIRATORY DISTRESS SYNDROME, ADULT; SURVIVORS;

EID: 85019702531     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-017-4827-8     Document Type: Article

References (45)

1. Cheung AM, Tansey CM, Tomlinson G, Diaz-Granados N, Matte A, Barr A, Mehta S, Mazer CD, Guest CB, Stewart TE, Al-Saidi F, Cooper AB, Cook D, Slutsky AS, Herridge MS (2006) Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med 174:538–544
2. Herridge MS, Tansey CM, Matte A, Tomlinson G, Diaz-Granados N, Cooper A, Guest CB, Mazer CD, Mehta S, Stewart TE, Kudlow P, Cook D, Slutsky AS, Cheung AM (2011) Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 364:1293–1304
3. Lone NI, Gillies MA, Haddow C, Dobbie R, Rowan KM, Wild SH, Murray GD, Walsh TS (2016) Five-year mortality and hospital costs associated with surviving intensive care. Am J Respir Crit Care Med 194:198–208
4. Needham DM, Dinglas VD, Morris PE, Jackson JC, Hough CL, Mendez-Tellez PA, Wozniak AW, Colantuoni E, Ely EW, Rice TW, Hopkins RO, NIH NHLBI ARDS Network (2013) Physical and cognitive performance of patients with acute lung injury 1 year after initial trophic versus full enteral feeding. EDEN trial follow-up. Am J Respir Crit Care Med 188:567–576
5. Huang M, Parker AM, Bienvenu OJ, Dinglas VD, Colantuoni E, Hopkins RO, Needham DM, National Institutes of Health National Heart, Lung, Blood Institute Acute Respiratory Distress Syndrome Network (2016) Psychiatric symptoms in acute respiratory distress syndrome survivors: a 1-year national multicenter study. Crit Care Med 44:954–965
6. Fan E, Dowdy DW, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Shanholtz C, Himmelfarb CR, Desai SV, Ciesla N, Herridge MS, Pronovost PJ, Needham DM (2014) Physical complications in acute lung injury survivors: a two-year longitudinal prospective study. Crit Care Med 42:849–859
7. Marti J, Hall P, Hamilton P, Lamb S, McCabe C, Lall R, Darbyshire J, Young D, Hulme C (2016) One-year resource utilisation, costs and quality of life in patients with acute respiratory distress syndrome (ARDS): secondary analysis of a randomised controlled trial. J Intensive Care 4:56
8. Clermont G, Kong L, Weissfeld LA, Lave JR, Rubenfeld GD, Roberts MS, Connors AF Jr, Bernard GR, Thompson BT, Wheeler AP, Angus DC, NHLBI ARDS Clinical Trials Network (2011) The effect of pulmonary artery catheter use on costs and long-term outcomes of acute lung injury. PLoS One 6:e22512
9. Ruhl AP, Huang M, Colantuoni E, Lord RK, Dinglas VD, Chong A, Sepulveda KA, Mendez-Tellez PA, Shanholtz CB, Steinwachs DM, Pronovost PJ, Needham DM (2017) Healthcare resource use and costs in long-term survivors of acute respiratory distress syndrome: a 5-year longitudinal cohort study. Crit Care Med 45:196–204
10. Lone NI, Seretny M, Wild SH, Rowan KM, Murray GD, Walsh TS (2013) Surviving intensive care: a systematic review of healthcare resource use after hospital discharge. Crit Care Med 41:1832–1843
11. Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT (2011) Randomized, placebo-controlled clinical trial of an aerosolized beta(2)-agonist for treatment of acute lung injury. Am J Respir Crit Care Med 184:561–568
12. Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, Moss M, Morris A, Dong N, Rock P (2012) Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA 307:795–803
13. Rice TW, Wheeler AP, Thompson BT, deBoisblanc BP, Steingrub J, Rock P (2011) Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA 306:1574–1581
14. National Heart, Lung, and Blood Institute ARDS Clinical Trials Network, Truwit JD, Bernard GR, Steingrub J, Matthay MA, Liu KD, Albertson TE, Brower RG, Shanholtz C, Rock P, Douglas IS, deBoisblanc BP, Hough CL, Hite RD, Thompson BT (2014) Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med 370:2191–2200
15. Needham DM, Colantuoni E, Dinglas VD, Hough CL, Wozniak AW, Jackson JC, Morris PE, Mendez-Tellez PA, Ely EW, Hopkins RO (2016) Rosuvastatin versus placebo for delirium in intensive care and subsequent cognitive impairment in patients with sepsis-associated acute respiratory distress syndrome: an ancillary study to a randomised controlled trial. Lancet Respir Med 4:203–212
16. Needham DM, Dinglas VD, Bienvenu OJ, Colantuoni E, Wozniak A, Rice TW, Hopkins RO (2013) One year outcomes of initial trophic vs full enteral feeding in acute lung injury patients: prospective follow-up ofthe EDEN randomized trial. BMJ 346:f1532
17. Needham DM, Dinglas VD, Morris PE, Jackson JC, Hough CL, Mendez-Tellez PA, Wozniak AW, Colantuoni E, Ely EW, Rice TW, Hopkins RO (2013) Physical and cognitive performance of patients with acute lung injury 1 year after initial trophic versus full enteral feeding. EDEN trial follow-up. Am J Respir Crit Care Med 188:567–576
18. Dinglas VD, Hopkins RO, Wozniak AW, Hough CL, Morris PE, Jackson JC, Mendez-Tellez PA, Bienvenu OJ, Ely EW, Colantuoni E, Needham DM (2016) One-year outcomes of rosuvastatin versus placebo in sepsis-associated acute respiratory distress syndrome: prospective follow-up of SAILS randomised trial. Thorax 71:401–410
19. Leidy NK, Knebel A (1999) Clinical validation of the functional performance inventory in patients with chronic obstructive pulmonary disease. Respir Care 44:932–939
20. Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361–370
21. Bienvenu OJ, Williams JB, Yang A, Hopkins RO, Needham DM (2013) Posttraumatic stress disorder in survivors of acute lung injury: evaluating the impact of Event Scale-Revised. Chest 144:24–31
22. Newkirk LA, Kim JM, Thompson JM, Tinklenberg JR, Yesavage JA, Taylor JL (2004) Validation of a 26-point telephone version of the Mini-Mental State Examination. J Geriatr Psychiatry Neurol 17:81–87
23. Group TE (1990) EuroQol–a new facility for the measurement of health-related quality of life. Health Policy 16:199–208
24. Ware JE Jr, Kosinski M, Dewey JE (2000) How to score version 2 of the SF-36 health survey. QualityMetric, Lincoln
25. Walters SJ, Brazier JE (2005) Comparison of the minimally important difference for two health state utility measures: EQ-5D and SF-6D. Qual Life Res 14:1523–1532
26. Samsa G, Edelman D, Rothman ML, Williams GR, Lipscomb J, Matchar D (1999) Determining clinically important differences in health status measures: a general approach with illustration to the Health Utilities Index Mark II. PharmacoEconomics 15:141–155
27. Puhan MA, Frey M, Buchi S, Schunemann HJ (2008) The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease. Health Qual Life Outcomes 6:46
28. Norman GR, Sloan JA, Wyrwich KW (2003) Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Med Care 41:582–592
29. Ruhl AP, Lord RK, Panek JA, Colantuoni E, Sepulveda KA, Chong A, Dinglas VD, Shanholtz CB, Pronovost PJ, Steinwachs DM, Needham DM (2015) Health care resource use and costs of two-year survivors of acute lung injury. An observational cohort study. Ann Am Thorac Soc 12:392–401
30. Sirey JA, Meyers BS, Teresi JA, Bruce ML, Ramirez M, Raue PJ, Perlick DA, Holmes D (2005) The Cornell Service Index as a measure of health service use. Psychiatr Serv 56:1564–1569
31. Means B (1989) Autobiographical memory for health-related events. No. 2. US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Center for Health Statistics
32. Coughlan D, Yeh ST, O’Neill C, Frick KD (2014) Evaluating direct medical expenditures estimation methods of adults using the medical expenditure panel survey: an example focusing on head and neck cancer. Value Health 17:90–97
33. Diehr P, Yanez D, Ash A, Hornbrook M, Lin DY (1999) Methods for analyzing health care utilization and costs. Annu Rev Public Health 20:125–144
34. Fine JG, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94:496–509
35. Hua M, Gong MN, Brady J, Wunsch H (2015) Early and late unplanned rehospitalizations for survivors of critical illness. Crit Care Med 43:430–438
36. Prescott HC, Langa KM, Liu V, Escobar GJ, Iwashyna TJ (2014) Increased 1-year healthcare use in survivors of severe sepsis. Am J Respir Crit Care Med 190:62–69
37. Liu V, Lei X, Prescott HC, Kipnis P, Iwashyna TJ, Escobar GJ (2014) Hospital readmission and healthcare utilization following sepsis in community settings. J Hosp Med 9:502–507
38. Goodwin AJ, Rice DA, Simpson KN, Ford DW (2015) Frequency, cost, and risk factors of readmissions among severe sepsis survivors. Crit Care Med 43:738–746
39. Hu J, Gonsahn MD, Nerenz DR (2014) Socioeconomic status and readmissions: evidence from an urban teaching hospital. Health Aff (Millwood) 33:778–785
40. Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI, RECOVER Program Investigators (Phase 1: towards RECOVER), Canadian Critical Care Trials Group (2016) The RECOVER program: disability risk groups and one year outcome after ≥7 days of mechanical ventilation. Am J Respir Crit Care Med 194(7):831–844
41. Lee H, Doig CJ, Ghali WA, Donaldson C, Johnson D, Manns B (2004) Detailed cost analysis of care for survivors of severe sepsis. Crit Care Med 32:981–985
42. Unroe M, Kahn JM, Carson SS, Govert JA, Martinu T, Sathy SJ, Clay AS, Chia J, Gray A, Tulsky JA, Cox CE (2010) One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: a cohort study. Ann Intern Med 153:167–175
43. Hussey PS, Schneider EC, Rudin RS, Fox DS, Lai J, Pollack CE (2014) Continuity and the costs of care for chronic disease. JAMA Intern Med 174:742–748
44. Davydow DS, Hough CL, Zatzick D, Katon WJ (2014) Psychiatric symptoms and acute care service utilization over the course of the year following medical-surgical ICU admission: a longitudinal investigation. Crit Care Med 42:2473–2481
45. Kjellsson G, Clarke P, Gerdtham UG (2014) Forgetting to remember or remembering to forget: a study of the recall period length in health care survey questions. J Health Econ 35:34–46