The reverse J-shaped association between serum total 25-hydroxyvitamin D concentration and all-cause mortality: The impact of assay standardization

American Journal of Epidemiology

Volumn 185, Issue 8, 2017, Pages 720-726

  Durazo Arvizu, Ramón A ^a   Dawson Hughes, Bess ^b   Kramer, Holly ^a   Cao, Guichan ^a   Merkel, Joyce ^c   Coates, Paul M ^c   Sempos, Christopher T ^c  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b TUFTS UNIVERSITY   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

25(OH)D; 25 hydroxyvitamin D; Mortality; NHANES; VDSP; Vitamin D; Vitamin D standardization program

Indexed keywords

25 HYDROXYVITAMIN D; 25-HYDROXYVITAMIN D; VITAMIN D;

BIOCHEMICAL COMPOSITION; DOSE-RESPONSE RELATIONSHIP; HEALTH RISK; HEALTH SURVEY; MORTALITY; PARTICIPATORY APPROACH; SERUM; STANDARDIZATION; VITAMIN;

ADULT; ALL CAUSE MORTALITY; ARTICLE; ETHNICITY; FEMALE; FOLLOW UP; HUMAN; LABORATORY TECHNIQUE; MAJOR CLINICAL STUDY; MALE; MORTALITY; NUTRITION; RACE; RISK FACTOR; SEASON; STANDARDIZATION; VITAMIN BLOOD LEVEL; ANALOGS AND DERIVATIVES; BLOOD; RISK; STATISTICAL ANALYSIS; STATISTICS; YOUNG ADULT;

DATA INTERPRETATION, STATISTICAL; FEMALE; HUMANS; MALE; MORTALITY; NUTRITION SURVEYS; RISK; RISK FACTORS; STATISTICS AS TOPIC; VITAMIN D; YOUNG ADULT;

EID: 85019651873     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kww244     Document Type: Article

References (24)

1. Sempos CT, Durazo-Arvizu RA, Dawson-Hughes B, et al. Is there a reverse J-shaped association between 25-hydroxyvitamin D and all-cause mortality? Results from the US nationally representative NHANES. J Clin Endocrinol Metab. 2013;98(7):3001-3009.
2. Zittermann A, Iodice S, Pilz S, et al. Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies. Am J Clin Nutr. 2012;95(1): 91-100.
3. Sohl E, de Jongh RT, Heymans MW, et al. Thresholds for serum 25(OH)D concentrations with respect to different outcomes. J Clin Endocrinol Metab. 2015;100(6): 2480-2488.
4. Carter GD. Accuracy of 25-hydroxyvitamin D assays: confronting the issues. Curr Drug Targets. 2011;12(1):19-28.
5. Binkley N, Krueger D, Cowgill CS, et al. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab. 2004;89(7): 3152-3157.
6. Cashman KD, Kiely M, Kinsella M, et al. An evaluation of the Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program's potential for national nutrition and health surveys. Am J Clin Nutr. 2013;97(6):1235-1242.
7. 2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry. Anal Chem. 2010;82(5):1942-1948.
8. 2 by using isotope-dilution liquid chromatography-tandem mass spectrometry. Clin Chem. 2011;57(3):441-448.
9. Looker AC, Pfeiffer CM, Lacher DA, et al. Serum 25-hydroxyvitamin D status of the US population: 1988-1994 compared with 2000-2004. Am J Clin Nutr. 2008;88(6): 1519-1527.
10. Schleicher RL, Sternberg MR, Lacher DA, et al. A methodbridging study for serum 25-hydroxyvitamin D to standardize historical radioimmunoassay data to liquid chromatography-tandem mass spectrometry. Natl Health Stat Report. 2016; (93):1-16.
11. Long JS, Freese J. Regression Models for Categorical Dependent Variables Using Stata. 2nd ed. College Station, TX: Stata Press; 2005.
12. Kahn HA, Sempos CT. Statistical Methods in Epidemiology. New York, NY: Oxford University Press; 1989.
13. Cashman KD, Hayes A, Galvin K, et al. Significance of serum 24,25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword? Clin Chem. 2015;61(4): 636-645.
14. Visser M, Deeg DJ, Puts MT, et al. Low serum concentrations of 25-hydroxyvitamin D in older persons and the risk of nursing home admission. Am J Clin Nutr. 2006;84(3): 616-622.
15. Jia X, Aucott LS, McNeill G. Nutritional status and subsequent all-cause mortality in men and women aged 75 years or over living in the community. Br J Nutr. 2007;98(3): 593-599.
16. Michaëlsson K, Baron JA, Snellman G, et al. Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr. 2010;92(4):841-848.
17. Johansson H, Odén A, Kanis J, et al. Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden. Osteoporos Int. 2012;23(3):991-999.
18. Durup D, Jørgensen HL, Christensen J, et al. A reverse J-shaped association of all-cause mortality with serum 25-hydroxyvitamin D in general practice: the CopD study. J Clin Endocrinol Metab. 2012;97(8):2644-2652.
19. Cashman KD, Dowling KG, Škrabáková Z, et al. Standardizing serum 25-hydroxyvitamin D data from four Nordic population samples using the Vitamin D Standardization Program protocols: shedding new light on vitamin D status in Nordic individuals. Scand J Clin Lab Invest. 2015;75(7):549-561.
20. Serafin K, Durazo-Arvizu R, Tian L, et al. Standardizing 25-hydroxyvitamin D values from the Canadian Health Measures Survey. Am J Clin Nutr. 2015;102(5):1044-1050.
21. Kiely M, Cashman KD; the ODIN Consortium. The ODIN project: development of food-based approaches for prevention of vitamin D deficiency throughout life. Nutr Bull. 2015;40(3): 235-246.
22. Binkley N, Sempos CT; Vitamin D Standardization Program (VDSP). Standardizing vitamin D assays: the way forward. J Bone Miner Res. 2014;29(8):1709-1714.
23. Sempos CT, Durazo-Arvizu RA, Binkley N, et al. Developing vitamin D dietary guidelines and the lack of 25-hydroxyvitamin D assay standardization: the ever-present past. J Steroid Biochem Mol Biol. 2016;164:115-119.
24. National Center for Health Statistics, Centers for Disease Control and Prevention. NHANES III (1988-1994). http://www.cdc.gov/nchs/nhanes/nhanes3.htm. Updated October 15, 2015. Accessed May 22, 2016.