Standardizing vitamin D assays: The way forward

Journal of Bone and Mineral Research

Volumn 29, Issue 8, 2014, Pages 1709-1714

  Binkley, Neil ^a   Sempos, Christopher T ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

25 Hydroxyvitamin D; Standardization; VDSP; Vitamin D; Vitamin D Standardization Program

Indexed keywords

VITAMIN D; 25-HYDROXYVITAMIN D;

ASSAY; CLINICAL LABORATORY; CLINICAL RESEARCH; EVIDENCE BASED PRACTICE; HEALTH PROGRAM; HEALTH SURVEY; HUMAN; NUTRITIONAL HEALTH; PRACTICE GUIDELINE; REVIEW; STANDARDIZATION; SYSTEMATIC REVIEW; VITAMIN D STANDARDIZATION PROGRAM; ANALOGS AND DERIVATIVES; BIOASSAY; BLOOD; BLOOD ANALYSIS; PROCEDURES; STANDARDS; VITAMIN D DEFICIENCY;

BIOLOGICAL ASSAY; BLOOD CHEMICAL ANALYSIS; HUMANS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84904621146     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2252     Document Type: Review

References (32)

1. IOM (Institute of Medicine). Dietary reference intakes for calcium and vitamin D. Washington, DC: The National Academies Press; 2011.
2. Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrin Metab. 2011; 96: 1911-30.
3. Binkley N, Krueger D, Cowgill CS, et al. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrin Metab. 2004; 89: 3152-7.
4. Carter GD., Accuracy of 25-hydroxyvitamin D assays: confronting the issues. Current Drug Targets. 2011; 12: 19-28.
5. Lai JK, Lucas RM, Banks E, Ponsonby AL., Ausimmune Investigator Group. Variability in vitamin D assays impairs clinical assessment of vitamin D status. Intern Med J. 2012; 42: 43-50.
6. Sempos CT, Vesper HW, Phinney KW, Thienpont LM, Coates PM., Vitamin D Standardization Program (VDSP). Vitamin D status as an international issue: national surveys and the problem of standardization. Scand J Clin Lab Invest Suppl. 2012 Apr; 243: 32-40.
7. Vesper HW, Thienpont LM., Traceability in laboratory medicine. Clin Chem. 2009; 55: 1067-75.
8. 2. Scand J Clin Lab Invest Suppl. 2012 Apr; 243: 41-9.
9. 2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry. Anal Chem. 2010; 82: 1942-8.
10. 2 by using isotope-dilution liquid chromatography-tandem mass spectrometry. Clin Chem. 2011; 57: 441-8.
11. Joint Committee for Traceability in Laboratory Medicine (JCTLM) database: Laboratory medicine and in vitro diagnostics [Internet]. Available from: http://www.bipm.org/jctlm/.
12. Looker AC, Pfeiffer CM, Lacher DA, Schleicher RL, Picciano MF, Yetley EA., Serum 25-hydroxyvitamin D status of the US population: 1988-1994 compared with 2000-2004. Am J Clin Nutr. 2008; 88: 1519-27.
13. Bunk DM., Materials and reference measurement procedures: an overview from a national metrology institute. Clin Biochem Rev. 2007; 28: 131-7.
14. Myers GL., Introduction to standardization of laboratory results. Steroids. 2008; 73: 1293-6.
15. Miller WG, Myers GL, Gantzer ML, et al. Roadmap for harmonization of clinical laboratory measurement procedures. Clin Chem. 2011; 57: 1108-17.
16. Miller WG, Jones GRD, Horowitz GL, Weykamp C., Proficiency testing/external quality assessment: Current challenges and future directions. Clin Chem. 2011; 57: 1670-80.
17. Stöckl D, Sluss PM, Thienpont LM., Specifications for trueness and precision of a reference measurement system for serum/plasma 25-hydroxyvitamin D analysis. Clin Chim Acta. 2009 Oct; 408 (1-2): 8-13.
18. Phinney KW, Bedner M, Tai SS, et al. Development and certification of a standard reference material for vitamin D metabolites in human serum. Anal Chem. 2012; 84: 956-62.
19. Miller WG, Myers CL., Commutability still matters. Clin Chem. 2013; 59: 1291-3.
20. Phinney KW, Merkel J, Sempos CT., VDSP Commutability Study results: total 25(OH)D nmol/L. Presentation given at the Vitamin D Standardization Program (VDSP) Symposium: Tools to Improve Laboratory Measurement, November 14, 2013, Gaithersburg, MD, USA. Available from: http://ods.od.nih.gov/News/VDSPSymposium- Agenda-2013.aspx.
21. Bedner M, Lippa KA, Tai SS., An assessment of 25-hydroxyvitamin D measurements in comparability studies conducted by the Vitamin D Metabolites Quality Assurance Program. Clin Chim Acta. 2013 Nov 15; 426: 6-11.
22. Cashman KD, Kiely M, Kinsella M, et al. An evaluation of the Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program's potential for national nutrition/health surveys. Am J Clin Nutr. 2013 Jun; 97 (6): 1235-42.
23. Lensmeyer G, Poquette M, Wiebe D, Binkley N., The C-3 epimer of 25-hydroxyvitamin D is present in adult serum. J Clin Endocrinol Metab. 2012; 97: 163-8.
24. 3 supplementation. J Steroid Biochem Mol Biol. 2011 Sep; 126 (3-5): 72-7.
25. Hollis BW, Wagner CL., Clinical review: the role of the parent compound vitamin D with respect to metabolism and function: why clinical dose intervals can affect clinical outcomes. J Clin Endocrinol Metab. 2013 Dec; 98 (12): 4619-28.
26. Powe CE, Evans MK, Wenger J, et al. Vitamin D-Binding protein and vitamin D status of black Americans and white Americans. N Engl J Med. 2013; 369: 1991-2000.
27. Bouillon R, Jones K, Schoenmakers I., Vitamin D-binding protein and vitamin D in blacks and whites. N Engl J Med. 2014 Feb 27; 370 (9): 879. [Letter to the Editor].
28. Hollis BW, Bikle DD., Vitamin D-binding protein and vitamin D in blacks and whites. N Engl J Med. 2014 Feb 27; 370 (9): 879-80. [Letter to the Editor].
29. Carter GD, Phinney KW., Assessing vitamin D status: time for a rethink ? Clin Chem. 2014 Jun; 60 (6): 809-11.
30. Handelsman DJ, Wartofsky L., Requirement for mass spectrometry sex steroid assays in the Journal of Clinical Endocrinology and Metabolism. J Clin Endocrinol Metab. 2013 Oct; 98 (10): 3971-3.
31. Wallace AM, Gibson S, de la Hunty A, Lamberg-Allardt C, Ashwell M., Measurement of 25-hydroxyvitamin D in the clinical laboratory: current procedures, performance characteristics and limitations. Steroids. 2010; 75: 477-88.
32. de la Hunty A, Wallace AM, Gibson S, Viljakainen H, Lamberg-Allardt C, Ashwell M., UK Food Standards Agency Workshop Consensus Report: the choice of method for measuring 25-hydroxyvitamin D to estimate vitamin D status for the UK National Diet and Nutrition Survey. Br J Nutr. 2010 Aug; 104 (4): 612-9.