Cellulosic ethanol: status and innovation

Current Opinion in Biotechnology

Volumn 45, Issue , 2017, Pages 202-211

  Lynd, Lee R ^a   Liang, Xiaoyu ^a   Biddy, Mary J ^b   Allee, Andrew ^a   Cai, Hao ^c   Foust, Thomas ^b   Himmel, Michael E ^b   Laser, Mark S ^a   Wang, Michael ^c   Wyman, Charles E ^d  

^a DARTMOUTH COLLEGE   (United States)

^b NATIONAL RENEWABLE ENERGY LABORATORY   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

^d University of California Riverside   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BOILERS; CELLULOSIC ETHANOL; COST REDUCTION; COSTS; ETHANOL; FUELS; GAS FUEL ANALYSIS;

CELLULOSIC FEEDSTOCKS; CONSOLIDATED BIO-PROCESSING; COST COMPETITIVENESS; CURRENT TECHNOLOGY; LIGNOCELLULOSE CONVERSIONS; SOLID FUEL BOILERS; THERMOCHEMICAL PRETREATMENT; THERMOPHILIC BACTERIA;

COST BENEFIT ANALYSIS;

ALCOHOL; AMYLASE; BIOFUEL; CARBOHYDRATE; CELLULASE; CELLULOSIC ETHANOL; ENZYME; LIGNOCELLULOSE; UNCLASSIFIED DRUG; CELLULOSE; LIGNIN;

BIOFUEL PRODUCTION; BIOMASS; BIOPROCESS; CLIMATE CHANGE; CLOSTRIDIUM THERMOCELLUM; CONSOLIDATED BIOPROCESSING; COST; FERMENTATION; GREENHOUSE GAS; NONHUMAN; PRIORITY JOURNAL; REVIEW; TECHNOLOGY; THERMOANAEROBACTERIUM SACCHAROLYTICUM; THERMOPHILIC BACTERIUM; ZYMOMONAS; ZYMOMONAS MOBILIS; ENZYMOLOGY; FUNGUS; METABOLISM;

BIOFUELS; CELLULASE; CELLULOSE; ETHANOL; FERMENTATION; FUNGI; LIGNIN;

EID: 85019592584     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2017.03.008     Document Type: Review

References (33)

1. • Fulton, L.M., Lynd, L.R., Körner, A., Greene, N., Tonachel, L.R., The need for biofuels as part of a low carbon energy future. Biofuels, Bioprod. Biorefin. 9 (2015), 476–483 Biofuels will likely be required in order to decarbonize about half of anticipated global transport energy demand according to the IEA two degree scenario.
2. • Souza, G.M., Victoria, R.L., Verdade, L.M., Joly, C.A., Netto, P.E.A., Cantarella, H., Chum, H.L., Diaz-Chavez, R., Fernandes, E., Fincher, G., et al. Bioenergy numbers. Souza, G.M., Victoria, R.L., Joly, C.A., Verdade, L.M., (eds.) Bioenergy & Sustainability: Bridging the Gaps, 2015, SCOPE, Paris, 28–57 Bioenergy Numbers is a useful compilation of information within a comprehensive report addressing various aspects of bioenergy merit and potential.
3. Jordan, N., Boody, G., Broussard, W., Glover, J.D., Keeney, D., McCown, B.H., McIsaac, G., Muller, M., Murray, H., Neal, J., et al. Sustainable development of the agricultural bio-economy. Science 316 (2007), 1570–1571.
4. Werling, B.P., Dickson, T.L., Isaacs, R., Gaines, H., Gratton, C., Gross, K.L., Liere, H., Malmstrom, C.M., Meehan, T.D., Ruan, L., et al. Perennial grasslands enhance biodiversity and multiple ecosystem services in bioenergy landscapes. Proc. Natl. Acad. Sci. U.S.A. 111 (2014), 1652–1657.
5. • Lynd, L.R., Sow, M., Chimphango, A.F., Cortez, L.A., Brito Cruz, C.H., Elmissiry, M., Laser, M., Mayaki, I.A., Moraes, M.A., Nogueira, L.A., et al. Bioenergy and African transformation. Biofuels Biotechnol., 8, 2015, 18 An exploration of the potential for realizing social benefits via bioenergy in Africa, informed by experience in Brazil.
6. Anderson, J.E., Dicicco, D.M., Ginder, J.M., Kramer, U., Leone, T.G., Raney-Pablo, H.E., Wallington, T.J., High octane number ethanol-gasoline blends: quantifying the potential benefits in the United States. Fuel 97 (2012), 585–594.
7. • Thomas, J.F., West, B.H., Huff, S.P., Effects of High-octane Ethanol Blends on Four Legacy Flex-fuel Vehicles, and a Turbocharged GDI Vehicle. 2015 ORNL/TM-2015/116 Addresses the potential to use ethanol in high-efficiency engines.
8. Crooks, E., The US Shale Revolution. 2015, Financ. Times.
9. Cardno ENTRIX, Current State of the US Ethanol Industry. 2010 DOE Subcontract 02, http://www1.eere.energy.gov/bioenergy/pdfs/current_state_of_the_us_ethanol_industry.pdf.
10. Klein-Marcuschamer, D., Oleskowicz-Popiel, P., Simmons, B.A., Blanch, H.W., The challenge of enzyme cost in the production of lignocellulosic biofuels. Biotechnol. Bioeng. 109 (2012), 1083–1087.
11. Stephen, J.D., Mabee, W.E., Saddler, J.N., Will second-generation ethanol be able to compete with first-generation ethanol? Opportunities for cost reduction. Biofuels, Bioprod. Bioref. 6 (2012), 159–176.
12. Lynd, L.R., Wyman, C.E., Gerngross, T.U., Biocommodity engineering. Biotechnol. Prog. 15 (1999), 777–793.
13. Himmel, M.E., Ding, S.-Y., Johnson, D.K., Adney, W.S., Nimlos, M.R., Brady, J.W., Foust, T.D., Biomass recalcitrance: engineering plants and enzymes for biofuels production. Science 315 (2007), 804–807.
14. • U.S. Department of Energy, Lignocellulosic Biomass for Advanced Biofuels and Bioproducts: Workshop Report., 2015 DOE SC-0170 An examination of the scientific barriers to expanding the bioeconomy based on lignocellulosic feedstocks, including recognition of the continuing importance of the recalcitrance barrier as an impediment to cost-competitive production.
15. Merrow, E.W., Chapel, S.W., Worthing, C., A Review of Cost Estimation in New Technologies. 1979, RAND Corporation.
16. Goldemberg, J., Coelho, S.T., Nastari, P.M., Lucon, O., Ethanol learning curve—the Brazilian experience. Biomass Bioenergy 26 (2004), 301–304.
17. Hettinga, W.G., Junginger, H.M., Dekker, S.C., Hoogwijk, M., McAloon, A.J., Hicks, K.B., Understanding the reductions in US corn ethanol production costs: an experience curve approach. Energy Policy 37 (2009), 190–203.
18. van den Wall Bake, J.D., Junginger, M., Faaij, A., Poot, T., Walter, A., Explaining the experience curve: cost reductions of Brazilian ethanol from sugarcane. Biomass Bioenergy 33 (2009), 644–658.
19. •• Paye, J.M.D., Guseva, A., Hammer, S.K., Gjersing, E., Davis, M.F., Davison, B.H., Olstad, J., Donohoe, B.S., Nguyen, T.Y., Wyman, C.E., et al. Biological lignocellulose solubilization: comparative evaluation of biocatalysts and enhancement via cotreatment. Biotechnol. Biofuels, 9, 2016, 8 A controlled comparison of lignocellulose solubilization involveing six biocatalysts and three feedstocks, including an initial report of cotreatment to augment fermentation by Clostridium thermocellum.
20. •• Lynd, L.R., Guss, A.M., Himmel, M.E., Beri, D., Herring, C., Holwerda, E.K., Murphy, S.J., Olson, D.G., Paye, J., Rydzak, T., et al. Advances in consolidated bioprocessing using Clostridium thermocellum and Thermoanaerobacter saccharolyticum. Wittmann, C., Liao, J.C., (eds.) Industrial Biotechnology: Microorganisms, 2017, Wiley-VCH Verlag GmbH & Co. KGaA, 365–394 Comprehensive comparative data is presented indicating thatC. thermocellum achieves 2- to 4-fold higher solubilization than industry-standard fungal cellulase on minimially-pretreated lignocellulose feedstocks. Recent progress at engineering two thermophilic anaerobes for improved ethanol production is also reviewed.
21. Resch, M.G., Donohoe, B.S., Baker, J.O., Decker, S.R., Bayer, E.A., Beckham, G.T., Himmel, M.E., Fungal cellulases and complexed cellulosomal enzymes exhibit synergistic mechanisms in cellulose deconstruction. Energy Environ. Sci. 6 (2013), 1858–1867.
22. • Xu, Q., Resch, M.G., Podkaminer, K., Yang, S., Baker, J.O., Donohoe, B.S., Wilson, C., Klingeman, D.M., Olson, D.G., Decker, S.R., et al. Dramatic performance of Clostridium thermocellum explained by its wide range of cellulase modalities. Sci. Adv., 2, 2016, e1501254 The latest perspectives on the mechanistic basis for the effectiveness of C. thermocellum at mediating solubilization of lignocellulosic feedstocks.
23. Balch, M.L., Holwerda, E.K., Davis, M., Sykes, R., Happs, R., Kumar, R., Wyman, C.E., Lynd, L.R., Lignocellulose fermentation and residue characterization for senescent switchgrass fermentation by Clostridium thernocellum in the presence and absence of continuous in-situ ball-milling. Energy Environ. Sci., 2017, 10.1039/C6EE03748H.
24. • Herring, C.D., Kenealy, W.R., Joe Shaw, A., Covalla, S.F., Olson, D.G., Zhang, J., Ryan Sillers, W., Tsakraklides, V., Bardsley, J.S., Rogers, S.R., et al. Strain and bioprocess improvement of a thermophilic anaerobe for the production of ethanol from wood. Biotechnol. Biofuels, 9, 2016, 125 Production of ethanol at commercially viable yields and titers is reported for engineered strains of a hemicellulose-fermenting thermophilic anaerobe.
25. Lynd, L.R., Weimer, P.J., van Zyl, W.H., Pretorius, I.S., Microbial cellulose utilization: fundamentals and biotechnology. Microbiol. Mol. Biol. Rev. 66 (2002), 506–577.
26. • Tian, L., Papanek, B., Olson, D.G., Rydzak, T., Holwerda, E.K., Zheng, T., Zhou, J., Maloney, M., Jiang, N., Giannone, R.J., et al. Simultaneous achievement of high ethanol yield and titer in Clostridium thermocellum. Biotechnol. Biofuels, 9, 2016, 116 A recent report of metabolic engineering of Costridium thermocellum for improved ethanol production.
27. • Humbird, D., Davis, R., Tao, L., Kinchin, C., Hsu, D., Aden, A., Schoen, P., Lukas, J., Olthof, B., Worley, M., et al. Process Design and Economics for Biochemical Conversion of Lignocellulosic Biomass to Ethanol: Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover., 2011 DOE report NREL/TP-5100-47764 The most recent published lignocellulose-to-ethanol process design by the National Renewable Energy Laboratory.
28. Systems Assessment Group, Energy Systems Division, Argonne National Laboratory, Summary of Expansions, Updates, and Results in GREET. 2016.
29. Lynd, L.R., Laser, M.S., Bransby, D., Dale, B.E., Davison, B., Hamilton, R., Himmel, M., Keller, M., McMillan, J.D., Sheehan, J., et al. How biotech can transform biofuels. Nat. Biotechnol. 26 (2008), 169–172.
30. Clomburg, J.M., Crumbley, A.M., Gonzalez, R., Industrial biomanufacturing: the future of chemical production. Science, 355, 2017.
31. Congressional Research Service, Pirog, R., Petroleum Refining: Economic Performance and Challenges for the Future. 2007 RL32248.
32. Lynd, L.R., Von Blottnitz, H., Tait, B., De Boer, J., Pretorius, I.S., Rumbold, K., Van Zyl, W.H., Converting plant biomass to fuels and commodity chemicals in South Africa: a third chapter?. S. Afr. J. Sci. 99 (2003), 499–507.
33. Lynd, L.R., Wyman, C., Laser, M., Johnson, D., Landucci, R., Strategic Biorefinery Analysis: Review of Existing Biorefinery Examples. 2005 NREL/SR-510-34895.