Isomethoxyneihumicin, a new cytotoxic agent produced by marine Nocardiopsis alba KM6-1

Journal of Antibiotics

Volumn 70, Issue 5, 2017, Pages 590-594

  Fukuda, Takashi ^a   Takahashi, Misaki ^a   Nagai, Kenichiro ^a   Harunari, Enjuro ^b   Imada, Chiaki ^b   Tomoda, Hiroshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT; ISOMETHOXYNEIHUMICIN; METHOXYNEIHUMICIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; LACTAM; PYRAZINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL DEATH; CHO CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; FEMALE; HCT 116 CELL LINE; HUMAN; HUMAN CELL; IC50; JURKAT CELL LINE; KERATINOCYTE; MARINE SPECIES; MOLECULAR WEIGHT; NOCARDIOPSACEAE; NOCARDIOPSIS ALBA KM6 1; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TAUTOMER; ACTINOMYCETALES; DOSE RESPONSE; DRUG EFFECTS; G2 PHASE CELL CYCLE CHECKPOINT; ISOLATION AND PURIFICATION; M PHASE CELL CYCLE CHECKPOINT; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACTINOMYCETALES; ANTINEOPLASTIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; INHIBITORY CONCENTRATION 50; JURKAT CELLS; LACTAMS; M PHASE CELL CYCLE CHECKPOINTS; MAGNETIC RESONANCE SPECTROSCOPY; PYRAZINES;

EID: 85019585400     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2016.152     Document Type: Article

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