Bicyclol exerts an anti-tumor effect via ROS-mediated endoplasmic reticulum stress in human renal cell carcinoma cells

Biomedicine and Pharmacotherapy

Volumn 91, Issue , 2017, Pages 1184-1192

  Wu, Jing ^a   Zheng, Weichao ^a   Rong, Ling ^b   Xing, Yingru ^a   Hu, Dong ^a  

^a ANHUI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Department of Neurology People's Hospital of Bozhou   (China)

Author keywords

Apoptosis; Bicyclol; ER stress; ROS

Indexed keywords

ANTINEOPLASTIC AGENT; BICYCLOL; CASPASE 3; CASPASE 8; CASPASE 9; GLUTATHIONE; INITIATION FACTOR 2ALPHA; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; BIPHENYL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; CELL CYCLE ARREST; CELL VIABILITY; CLONOGENIC ASSAY; COLONY FORMATION; CONCENTRATION (PARAMETERS); CONTINUOUS INFUSION; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC50; KIDNEY CARCINOMA; PRIORITY JOURNAL; RENAL CANCER CELL LINE; WESTERN BLOTTING; CELL CYCLE; CELL SURVIVAL; DRUG EFFECTS; KIDNEY TUMOR; METABOLISM; RENAL CELL CARCINOMA; TUMOR CELL LINE;

APOPTOSIS; BIPHENYL COMPOUNDS; CARCINOMA, RENAL CELL; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; HUMANS; KIDNEY NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 85019395310     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.05.041     Document Type: Article

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