메뉴 건너뛰기




Volumn 14, Issue 3, 2017, Pages 323-328

Tranexamic acid in total hip arthroplasty: A recursive cumulative meta-analysis of randomized controlled trials and assessment of publication bias

Author keywords

Fisher method; Rosenthal method; Trim and fill method

Indexed keywords

PLACEBO; TRANEXAMIC ACID;

EID: 85019373877     PISSN: None     EISSN: 0972978X     Source Type: Journal    
DOI: 10.1016/j.jor.2017.05.004     Document Type: Review
Times cited : (8)

References (39)
  • 1
    • 85006210396 scopus 로고    scopus 로고
    • Tranexamic acid for the prevention and management of orthopaedic surgical haemorrhage: current evidence
    • Kim, C., Park, S.S.-H., Davey, J.R., Tranexamic acid for the prevention and management of orthopaedic surgical haemorrhage: current evidence. J Blood Med 6 (2015), 239–244.
    • (2015) J Blood Med , vol.6 , pp. 239-244
    • Kim, C.1    Park, S.S.-H.2    Davey, J.R.3
  • 2
    • 85014245390 scopus 로고    scopus 로고
    • Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: A meta-analysis
    • Zhang, P., Liang, Y., Chen, P., Fang, Y., He, J., Wang, J., Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: A meta-analysis. BMC Musculoskelet Disord, 18, 2017, 90.
    • (2017) BMC Musculoskelet Disord , vol.18 , pp. 90
    • Zhang, P.1    Liang, Y.2    Chen, P.3    Fang, Y.4    He, J.5    Wang, J.6
  • 3
    • 85007356679 scopus 로고    scopus 로고
    • Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty A meta-analysis
    • Lin, C., Qi, Y., Jie, L., et al. Is combined topical with intravenous tranexamic acid superior than topical, intravenous tranexamic acid alone and control groups for blood loss controlling after total knee arthroplasty A meta-analysis. Medicine (Baltimore), 95, 2016, 51.
    • (2016) Medicine (Baltimore) , vol.95 , pp. 51
    • Lin, C.1    Qi, Y.2    Jie, L.3
  • 4
    • 0023122841 scopus 로고
    • Antifibrinolytic therapy for prevention of hemorrhage during surgery of the thyroid gland
    • Auvinen, O., Baer, G.A., Nordback, I., Saaristo, J., Antifibrinolytic therapy for prevention of hemorrhage during surgery of the thyroid gland. Klin Wochenschr 65 (1987), 253–255.
    • (1987) Klin Wochenschr , vol.65 , pp. 253-255
    • Auvinen, O.1    Baer, G.A.2    Nordback, I.3    Saaristo, J.4
  • 5
    • 84958169836 scopus 로고    scopus 로고
    • The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis
    • Chen, S., Wu, K., Kong, G., Feng, W., Deng, Z., Wang, H., The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis. BMC Musculoskelet Disord, 17, 2016, 81.
    • (2016) BMC Musculoskelet Disord , vol.17 , pp. 81
    • Chen, S.1    Wu, K.2    Kong, G.3    Feng, W.4    Deng, Z.5    Wang, H.6
  • 6
    • 78651225746 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement
    • Sukeik, M., Alshryda, S., Haddad, F.S., Mason, J.M., Systematic review and meta-analysis of the use of tranexamic acid in total hip replacement. J Bone Joint Surg Br 93 (2011), 39–46.
    • (2011) J Bone Joint Surg Br , vol.93 , pp. 39-46
    • Sukeik, M.1    Alshryda, S.2    Haddad, F.S.3    Mason, J.M.4
  • 7
    • 84986569358 scopus 로고    scopus 로고
    • Grey matters; on the importance of publication bias in systematic reviews
    • Winters, M., Weir, A., Grey matters; on the importance of publication bias in systematic reviews. Br J Sports Med 51 (2017), 488–489.
    • (2017) Br J Sports Med , vol.51 , pp. 488-489
    • Winters, M.1    Weir, A.2
  • 8
    • 85007454027 scopus 로고    scopus 로고
    • Comparing efficacy and safety of 2 methods of tranexamic acid administration in reducing blood loss following total knee arthroplasty A meta-analysis
    • Fu, Y., Shi, Z., Han, B., et al. Comparing efficacy and safety of 2 methods of tranexamic acid administration in reducing blood loss following total knee arthroplasty A meta-analysis. Medicine (Baltimore), 95, 2016, 50.
    • (2016) Medicine (Baltimore) , vol.95 , pp. 50
    • Fu, Y.1    Shi, Z.2    Han, B.3
  • 9
    • 84965017920 scopus 로고    scopus 로고
    • What is the optimal approach for tranexamic acid application in patients with unilateral total hip arthroplasty?
    • Zhang, Y., Zhang, L., Ma, X., et al. What is the optimal approach for tranexamic acid application in patients with unilateral total hip arthroplasty?. Orthopade 45 (2016), 616–621.
    • (2016) Orthopade , vol.45 , pp. 616-621
    • Zhang, Y.1    Zhang, L.2    Ma, X.3
  • 10
    • 84904895520 scopus 로고    scopus 로고
    • Accumulating research: A systematic account of how cumulative meta-analyses would have provided knowledge, improved health, reduced harm and saved resources
    • e102670
    • Clarke, M., Brice, A., Chalmers, I., Accumulating research: A systematic account of how cumulative meta-analyses would have provided knowledge, improved health, reduced harm and saved resources. PLoS ONE, 9(7), 2014, 10.1371/journal.pone.0102670 e102670.
    • (2014) PLoS ONE , vol.9 , Issue.7
    • Clarke, M.1    Brice, A.2    Chalmers, I.3
  • 11
    • 84991111473 scopus 로고    scopus 로고
    • Cumulative meta-analysis by precision as a method to evaluate publication bias
    • Atakpo, P., Vassar, M., Cumulative meta-analysis by precision as a method to evaluate publication bias. J Dermatol Sci 83 (2016), 240–253.
    • (2016) J Dermatol Sci , vol.83 , pp. 240-253
    • Atakpo, P.1    Vassar, M.2
  • 12
    • 33746341926 scopus 로고
    • The File Drawer Problem and tolerance for null results
    • Rosenthal, R., The File Drawer Problem and tolerance for null results. Psychol Bull 86 (1979), 638–641.
    • (1979) Psychol Bull , vol.86 , pp. 638-641
    • Rosenthal, R.1
  • 13
    • 0033934949 scopus 로고    scopus 로고
    • Trim and Fill A simple Funnel-Plot-based method of testing and adjusting for publication bias in meta-analysis
    • Duval, S., Tweedie, R., Trim and Fill A simple Funnel-Plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56 (2000), 455–463.
    • (2000) Biometrics , vol.56 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 14
    • 84925548115 scopus 로고    scopus 로고
    • The PRISMA Group: preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement
    • Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., The PRISMA Group: preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement. J Clin Epidemiol 62 (2009), 1006–1012.
    • (2009) J Clin Epidemiol , vol.62 , pp. 1006-1012
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 16
    • 84955367501 scopus 로고    scopus 로고
    • Advances in the meta-analysis of heterogeneous clinical trials II: The quality effects model
    • Doi, S.A., Barendregt, J.J., Khan, S., Thalib, L., Williams, G.M., Advances in the meta-analysis of heterogeneous clinical trials II: The quality effects model. Contemp Clin Trials 45 (2015), 123–129.
    • (2015) Contemp Clin Trials , vol.45 , pp. 123-129
    • Doi, S.A.1    Barendregt, J.J.2    Khan, S.3    Thalib, L.4    Williams, G.M.5
  • 17
    • 84962760888 scopus 로고    scopus 로고
    • User Manual for Meta-Essentials: Workbooks for Meta-analysis (Version 1.0)
    • Rotterdam, The Netherlands: Erasmus Research Institute of Management. Available from =. Accessed on 12 Mar 17]
    • Van Rhee, H.J., Suurmond Hak, R.T., User Manual for Meta-Essentials: Workbooks for Meta-analysis (Version 1.0). 2017, Rotterdam, The Netherlands: Erasmus Research Institute of Management. Available from www.erim.eur.nl/research-support/meta-essentials =. Accessed on 12 Mar 17].
    • (2017)
    • Van Rhee, H.J.1    Suurmond Hak, R.T.2
  • 18
    • 0034768780 scopus 로고    scopus 로고
    • Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations
    • Benoni, G., Fredin, H., Knebel, R., Nilsson, P., Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations. Acta Orthop Scand 72 (2001), 442–448.
    • (2001) Acta Orthop Scand , vol.72 , pp. 442-448
    • Benoni, G.1    Fredin, H.2    Knebel, R.3    Nilsson, P.4
  • 19
    • 22844450760 scopus 로고    scopus 로고
    • Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients
    • Johansson, T., Pettersson, L.G., Lisander, B., Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients. Acta Orthop 76 (2005), 314–319.
    • (2005) Acta Orthop , vol.76 , pp. 314-319
    • Johansson, T.1    Pettersson, L.G.2    Lisander, B.3
  • 20
    • 84908254118 scopus 로고    scopus 로고
    • Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty
    • Wei, W., Wei, B., Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty. J Arthroplasty 29 (2014), 2113–2116.
    • (2014) J Arthroplasty , vol.29 , pp. 2113-2116
    • Wei, W.1    Wei, B.2
  • 21
    • 33644853357 scopus 로고    scopus 로고
    • Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis
    • Niskanen, R.O., Korkala, O.L., Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis. Acta Orthop 76 (2005), 829–832.
    • (2005) Acta Orthop , vol.76 , pp. 829-832
    • Niskanen, R.O.1    Korkala, O.L.2
  • 22
    • 84978821785 scopus 로고    scopus 로고
    • Tranexamic acid administration in primary total hip arthroplasty: a randomized controlled trial of intravenous combined with topical versus single-dose intravenous administration
    • Yi, Z., Bin, S., Jing, Y., Zongke, Z., Pengde, K., Fuxing, P., Tranexamic acid administration in primary total hip arthroplasty: a randomized controlled trial of intravenous combined with topical versus single-dose intravenous administration. J Bone Joint Surg Am 98 (2016), 983–991.
    • (2016) J Bone Joint Surg Am , vol.98 , pp. 983-991
    • Yi, Z.1    Bin, S.2    Jing, Y.3    Zongke, Z.4    Pengde, K.5    Fuxing, P.6
  • 23
    • 84957869483 scopus 로고    scopus 로고
    • Combined use of intravenous and topical tranexamic acid following cementless total hip arthroplasty: a randomised clinical trial
    • Xie, J., Ma, J., Yue, C., Kang, P., Pei, F., Combined use of intravenous and topical tranexamic acid following cementless total hip arthroplasty: a randomised clinical trial. Hip Int 26 (2016), 36–42.
    • (2016) Hip Int , vol.26 , pp. 36-42
    • Xie, J.1    Ma, J.2    Yue, C.3    Kang, P.4    Pei, F.5
  • 24
    • 84961566757 scopus 로고    scopus 로고
    • Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: a double-blind, randomized controlled trial of different doses
    • Wang, C., Kang, P., Ma, J., Yue, C., Xie, J., Pei, F., Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: a double-blind, randomized controlled trial of different doses. Thromb Res 141 (2016), 119–123.
    • (2016) Thromb Res , vol.141 , pp. 119-123
    • Wang, C.1    Kang, P.2    Ma, J.3    Yue, C.4    Xie, J.5    Pei, F.6
  • 25
    • 84912528650 scopus 로고    scopus 로고
    • Topical application of tranexamic acid in primary total hip arthroplasty: a randomized double-blind controlled trial
    • Yue, C., Kang, P., Yang, P., Xie, J., Pei, F., Topical application of tranexamic acid in primary total hip arthroplasty: a randomized double-blind controlled trial. J Arthroplasty 29 (2014), 2452–2456.
    • (2014) J Arthroplasty , vol.29 , pp. 2452-2456
    • Yue, C.1    Kang, P.2    Yang, P.3    Xie, J.4    Pei, F.5
  • 26
    • 84966603253 scopus 로고    scopus 로고
    • The efficacy and safety of combination of intravenous and topical tranexamic acid in revision hip arthroplasty: a randomized, controlled trial
    • Wu, Y.G., Zeng, Y., Yang, T.M., Si, H.B., Cao, F., Shen, B., The efficacy and safety of combination of intravenous and topical tranexamic acid in revision hip arthroplasty: a randomized, controlled trial. J Arthroplasty 31 (2016), 2548–2553.
    • (2016) J Arthroplasty , vol.31 , pp. 2548-2553
    • Wu, Y.G.1    Zeng, Y.2    Yang, T.M.3    Si, H.B.4    Cao, F.5    Shen, B.6
  • 27
    • 85019349720 scopus 로고    scopus 로고
    • OBTAIN A: Outcome benefits of tranexamic acid in hip arthroplasty. A randomized double-blinded controlled trial
    • S0883-5403(16)30845-2
    • Fraval, A., Effeney, P., Fiddelaers, L., Smith, B., Towell, B., Tran, P., OBTAIN A: Outcome benefits of tranexamic acid in hip arthroplasty. A randomized double-blinded controlled trial. J Arthroplasty, 2016 S0883-5403(16)30845-2.
    • (2016) J Arthroplasty
    • Fraval, A.1    Effeney, P.2    Fiddelaers, L.3    Smith, B.4    Towell, B.5    Tran, P.6
  • 28
    • 84891890096 scopus 로고    scopus 로고
    • Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial
    • Oremus, K., Sostaric, S., Trkulja, V., Haspl, M., Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial. Transfusion 54 (2014), 31–41.
    • (2014) Transfusion , vol.54 , pp. 31-41
    • Oremus, K.1    Sostaric, S.2    Trkulja, V.3    Haspl, M.4
  • 29
    • 82255176890 scopus 로고    scopus 로고
    • Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray
    • McConnell, J.S., Shewale, S., Munro, N.A., Shah, K., Deakin, A.H., Kinninmonth, A.W., Reduction of blood loss in primary hip arthroplasty with tranexamic acid or fibrin spray. Acta Orthop 82 (2011), 660–663.
    • (2011) Acta Orthop , vol.82 , pp. 660-663
    • McConnell, J.S.1    Shewale, S.2    Munro, N.A.3    Shah, K.4    Deakin, A.H.5    Kinninmonth, A.W.6
  • 30
    • 0033848970 scopus 로고    scopus 로고
    • Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty
    • Benoni, G., Lethagen, S., Nilsson, P., Fredin, H., Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty. Acta Orthop Scand 71 (2000), 250–254.
    • (2000) Acta Orthop Scand , vol.71 , pp. 250-254
    • Benoni, G.1    Lethagen, S.2    Nilsson, P.3    Fredin, H.4
  • 31
    • 75649122555 scopus 로고    scopus 로고
    • The effect of tranexamic acid on reducing blood loss in cementless total hip arthroplasty under epidural anesthesia
    • Kazemi, S.M., Mosaffa, F., Eajazi, A., et al. The effect of tranexamic acid on reducing blood loss in cementless total hip arthroplasty under epidural anesthesia. Orthopedics, 33, 2010, 17.
    • (2010) Orthopedics , vol.33 , pp. 17
    • Kazemi, S.M.1    Mosaffa, F.2    Eajazi, A.3
  • 32
    • 84869087886 scopus 로고    scopus 로고
    • Tranexamic acid for reduction of blood loss during total hip arthroplasty
    • Imai, N., Dohmae, Y., Suda, K., Miyasaka, D., Ito, T., Endo, N., Tranexamic acid for reduction of blood loss during total hip arthroplasty. J Arthroplasty 27 (2012), 1838–1843.
    • (2012) J Arthroplasty , vol.27 , pp. 1838-1843
    • Imai, N.1    Dohmae, Y.2    Suda, K.3    Miyasaka, D.4    Ito, T.5    Endo, N.6
  • 34
    • 2642576572 scopus 로고    scopus 로고
    • Bone bleeding during total hip arthroplasty after administration of tranexamic acid
    • Garneti, N., Field, J., Bone bleeding during total hip arthroplasty after administration of tranexamic acid. J Arthroplasty 19 (2004), 488–492.
    • (2004) J Arthroplasty , vol.19 , pp. 488-492
    • Garneti, N.1    Field, J.2
  • 35
    • 84965017920 scopus 로고    scopus 로고
    • What is the optimal approach for tranexamic acid application in patients with unilateral total hip arthroplasty?
    • Zhang, Y., Zhang, L., Ma, X., et al. What is the optimal approach for tranexamic acid application in patients with unilateral total hip arthroplasty?. Orthopade 45 (2016), 616–621.
    • (2016) Orthopade , vol.45 , pp. 616-621
    • Zhang, Y.1    Zhang, L.2    Ma, X.3
  • 36
    • 2142656471 scopus 로고    scopus 로고
    • Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases
    • Yamasaki, S., Masuhara, K., Fuji, T., Tranexamic acid reduces blood loss after cementless total hip arthroplasty-prospective randomized study in 40 cases. Int Orthop 28 (2004), 69–73.
    • (2004) Int Orthop , vol.28 , pp. 69-73
    • Yamasaki, S.1    Masuhara, K.2    Fuji, T.3
  • 37
    • 85014217932 scopus 로고    scopus 로고
    • A prospective randomized controlled study of tranexamic acid used in different ways to reduce blood loss in total hip arthroplasty
    • Lu, C., Guo, H., Hao, Y.Q., Chen, X.S., Cai, Y.Z., Xu, P., A prospective randomized controlled study of tranexamic acid used in different ways to reduce blood loss in total hip arthroplasty. CJBJS 9 (2016), 140–144.
    • (2016) CJBJS , vol.9 , pp. 140-144
    • Lu, C.1    Guo, H.2    Hao, Y.Q.3    Chen, X.S.4    Cai, Y.Z.5    Xu, P.6
  • 38
    • 0035230145 scopus 로고    scopus 로고
    • Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
    • CD001886
    • Henry, D.A., Moxey, A.J., Carless, P.A., et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev, 1, 2001 CD001886.
    • (2001) Cochrane Database Syst Rev , vol.1
    • Henry, D.A.1    Moxey, A.J.2    Carless, P.A.3
  • 39
    • 84861503406 scopus 로고    scopus 로고
    • Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis
    • Ker, K., Perel, P., Shakur, H., Roberts, I., Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ, 344, 2012, e3054.
    • (2012) BMJ , vol.344 , pp. e3054
    • Ker, K.1    Perel, P.2    Shakur, H.3    Roberts, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.