Antibiotics-induced gut microbiota dysbiosis promotes tumor initiation via affecting APC-Th1 development in mice

Biochemical and Biophysical Research Communications

Volumn 488, Issue 2, 2017, Pages 418-424

  Xu, Chengming ^a   Ruan, Banjun ^a   Jiang, Yinghao ^a   Xue, Ting ^a   Wang, Zhenyu ^a   Lu, Huanyu ^a   Wei, Ming ^b   Wang, Shan ^c   Ye, Zicheng ^a   Zhai, Dongsheng ^a   Wang, Li ^a   Lu, Zifan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b XI'AN MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antigen presenting cells; Gut microbiota; LPS; Tumor immune microenvironment

Indexed keywords

ANTIBIOTIC AGENT; B7 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12P35; INTERLEUKIN 12P40; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR; ANTIINFECTIVE AGENT; APC PROTEIN; APC PROTEIN, HUMAN; CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; CYTOKINE RELEASE; DYSBIOSIS; FEMALE; INTESTINE FLORA; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; TUMOR MICROENVIRONMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL PROLIFERATION; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; MELANOMA; ORAL DRUG ADMINISTRATION; PATHOLOGY; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR CELL LINE;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GASTROINTESTINAL MICROBIOME; INJECTIONS, SUBCUTANEOUS; LIPOPOLYSACCHARIDES; MELANOMA; MICE; MICE, INBRED C57BL; TH1 CELLS;

EID: 85019351319     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.05.071     Document Type: Article

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