-
1
-
-
84942063845
-
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
-
Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM, Xing Y, Carstens RP (2015) The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. eLife 4:e08954
-
(2015)
Elife
, vol.4
-
-
Bebee, T.W.1
Park, J.W.2
Sheridan, K.I.3
Warzecha, C.C.4
Cieply, B.W.5
Rohacek, A.M.6
Xing, Y.7
Carstens, R.P.8
-
2
-
-
84946601363
-
ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation
-
Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A (2015) ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nat Commun 6:8768
-
(2015)
Nat Commun
, vol.6
, pp. 8768
-
-
Bhate, A.1
Parker, D.J.2
Bebee, T.W.3
Ahn, J.4
Arif, W.5
Rashan, E.H.6
Chorghade, S.7
Chau, A.8
Lee, J.H.9
Anakk, S.10
Carstens, R.P.11
Xiao, X.12
Kalsotra, A.13
-
3
-
-
84875208735
-
Dynamic integration of splicing within gene regulatory pathways
-
Braunschweig U, Gueroussov S, Plocik AM, Graveley BR, Blencowe BJ (2013) Dynamic integration of splicing within gene regulatory pathways. Cell 152:1252-1269
-
(2013)
Cell
, vol.152
, pp. 1252-1269
-
-
Braunschweig, U.1
Gueroussov, S.2
Plocik, A.M.3
Graveley, B.R.4
Blencowe, B.J.5
-
4
-
-
79952227361
-
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
-
Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J, Cheng C (2011) CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest 121:1064-1074
-
(2011)
J Clin Invest
, vol.121
, pp. 1064-1074
-
-
Brown, R.L.1
Reinke, L.M.2
Damerow, M.S.3
Perez, D.4
Chodosh, L.A.5
Yang, J.6
Cheng, C.7
-
5
-
-
84885963684
-
Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2
-
Cieply B, Farris J, Denvir J, Ford HL, Frisch SM (2013) Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2. Cancer Res 73:6299-6309
-
(2013)
Cancer Res
, vol.73
, pp. 6299-6309
-
-
Cieply, B.1
Farris, J.2
Denvir, J.3
Ford, H.L.4
Frisch, S.M.5
-
6
-
-
0034964418
-
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn J, Berx G, Vermassen P, Verschueren K, van Grunsven L, Bruyneel E, Mareel M, Huylebroeck D, van Roy F (2001) The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell 7:1267-1278
-
(2001)
. Mol Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
van Grunsven, L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
van Roy, F.9
-
7
-
-
78049416081
-
Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
-
David CJ, Manley JL (2010) Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev 24:2343-2364
-
(2010)
Genes Dev
, vol.24
, pp. 2343-2364
-
-
David, C.J.1
Manley, J.L.2
-
8
-
-
84861302942
-
Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing
-
Dittmar KA, Jiang P, Park JW, Amirikian K, Wan J, Shen S, Xing Y, Carstens RP (2012) Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing. Mol Cell Biol 32:1468-1482
-
(2012)
Mol Cell Biol
, vol.32
, pp. 1468-1482
-
-
Dittmar, K.A.1
Jiang, P.2
Park, J.W.3
Amirikian, K.4
Wan, J.5
Shen, S.6
Xing, Y.7
Carstens, R.P.8
-
9
-
-
20144388095
-
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
-
Eger A, Aigner K, Sonderegger S, Dampier B, Oehler S, Schreiber M, Berx G, Cano A, Beug H, Foisner R (2005) DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 24:2375-2385
-
(2005)
Oncogene
, vol.24
, pp. 2375-2385
-
-
Eger, A.1
Aigner, K.2
Sonderegger, S.3
Dampier, B.4
Oehler, S.5
Schreiber, M.6
Berx, G.7
Cano, A.8
Beug, H.9
Foisner, R.10
-
11
-
-
84883193285
-
The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells
-
Fagoonee S, Bearzi C, Di Cunto F, Clohessy JG, Rizzi R, Reschke M, Tolosano E, Provero P, Pandolfi PP, Silengo L, Altruda F (2013) The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells. PLoS One 8:e72300
-
(2013)
Plos One
, pp. 8
-
-
Fagoonee, S.1
Bearzi, C.2
Di Cunto, F.3
Clohessy, J.G.4
Rizzi, R.5
Reschke, M.6
Tolosano, E.7
Provero, P.8
Pandolfi, P.P.9
Silengo, L.10
Altruda, F.11
-
12
-
-
1042278129
-
Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase
-
Fiegen D, Haeusler LC, Blumenstein L, Herbrand U, Dvorsky R, Vetter IR, Ahmadian MR (2004) Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase. J Biol Chem 279:4743-4749
-
(2004)
J Biol Chem
, vol.279
, pp. 4743-4749
-
-
Fiegen, D.1
Haeusler, L.C.2
Blumenstein, L.3
Herbrand, U.4
Dvorsky, R.5
Vetter, I.R.6
Ahmadian, M.R.7
-
13
-
-
84863203049
-
TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP
-
Horiguchi K, Sakamoto K, Koinuma D, Semba K, Inoue A, Inoue S, Fujii H, Yamaguchi A, Miyazawa K, Miyazono K, Saitoh M (2012) TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP. Oncogene 31:3190-3201
-
(2012)
Oncogene
, vol.31
, pp. 3190-3201
-
-
Horiguchi, K.1
Sakamoto, K.2
Koinuma, D.3
Semba, K.4
Inoue, A.5
Inoue, S.6
Fujii, H.7
Yamaguchi, A.8
Miyazawa, K.9
Miyazono, K.10
Saitoh, M.11
-
14
-
-
84894463722
-
Novel insights into breast cancer genetic variance through RNA sequencing
-
Horvath A, Pakala SB, Mudvari P, Reddy SD, Ohshiro K, Casimiro S, Pires R, Fuqua SA, Toi M, Costa L, Nair SS, Sukumar S, Kumar R (2013) Novel insights into breast cancer genetic variance through RNA sequencing. Sci Rep 3:2256
-
(2013)
Sci Rep
, vol.3
, pp. 2256
-
-
Horvath, A.1
Pakala, S.B.2
Mudvari, P.3
Reddy, S.D.4
Ohshiro, K.5
Casimiro, S.6
Pires, R.7
Fuqua, S.A.8
Toi, M.9
Costa, L.10
Nair, S.S.11
Sukumar, S.12
Kumar, R.13
-
15
-
-
84957310749
-
The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins
-
Hoshi Y, Endo K, Shirakihara T, Fukagawa A, Miyazawa K, Saitoh M (2016) The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins. FEBS Lett 590:270-278
-
(2016)
FEBS Lett
, vol.590
, pp. 270-278
-
-
Hoshi, Y.1
Endo, K.2
Shirakihara, T.3
Fukagawa, A.4
Miyazawa, K.5
Saitoh, M.6
-
16
-
-
84907483753
-
Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms
-
Ishii H, Saitoh M, Sakamoto K, Kondo T, Katoh R, Tanaka S, Motizuki M, Masuyama K, Miyazawa K (2014) Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J Biol Chem 289:27386-27399
-
(2014)
J Biol Chem
, vol.289
, pp. 27386-27399
-
-
Ishii, H.1
Saitoh, M.2
Sakamoto, K.3
Kondo, T.4
Katoh, R.5
Tanaka, S.6
Motizuki, M.7
Masuyama, K.8
Miyazawa, K.9
-
17
-
-
79952528125
-
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
-
Ishimoto T, Nagano O, Yae T, Tamada M, Motohara T, Oshima H, Oshima M, Ikeda T, Asaba R, Yagi H, Masuko T, Shimizu T, Ishikawa T, Kai K, Takahashi E, Imamura Y, Baba Y, Ohmura M, Suematsu M, Baba H, Saya H (2011) CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell 19:387-400
-
(2011)
Cancer Cell
, vol.19
, pp. 387-400
-
-
Ishimoto, T.1
Nagano, O.2
Yae, T.3
Tamada, M.4
Motohara, T.5
Oshima, H.6
Oshima, M.7
Ikeda, T.8
Asaba, R.9
Yagi, H.10
Masuko, T.11
Shimizu, T.12
Ishikawa, T.13
Kai, K.14
Takahashi, E.15
Imamura, Y.16
Baba, Y.17
Ohmura, M.18
Suematsu, M.19
Baba, H.20
Saya, H.21
more..
-
18
-
-
0033581944
-
Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
-
Jordan P, Brazåo R, Boavida MG, Gespach C, Chastre E (1999) Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors. Oncogene 18:6835-6839
-
(1999)
Oncogene
, vol.18
, pp. 6835-6839
-
-
Jordan, P.1
Brazåo, R.2
Boavida, M.G.3
Gespach, C.4
Chastre, E.5
-
19
-
-
84865769799
-
Splicing in oncogenesis and tumor suppression
-
Kaida D, Schneider-Poesch T, Yoshida M (2012) Splicing in oncogenesis and tumor suppression. Cancer Sci 103:1611-1616
-
(2012)
Cancer Sci
, vol.103
, pp. 1611-1616
-
-
Kaida, D.1
Schneider-Poesch, T.2
Yoshida, M.3
-
20
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119:1420-1428
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
21
-
-
59449096532
-
RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer
-
Leontieva OV, Ionov Y (2009) RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer. Cell Cycle 8:490-497
-
(2009)
Cell Cycle
, vol.8
, pp. 490-497
-
-
Leontieva, O.V.1
Ionov, Y.2
-
22
-
-
84892163927
-
Exo70 isoform switching upon epithelial-mesenchymal transition mediates cancer cell invasion
-
Lu H, Liu J, Liu S, Zeng J, Ding D, Carstens RP, Cong Y, Xu X, Guo W (2013) Exo70 isoform switching upon epithelial-mesenchymal transition mediates cancer cell invasion. Dev Cell 27:560-573
-
(2013)
Dev Cell
, vol.27
, pp. 560-573
-
-
Lu, H.1
Liu, J.2
Liu, S.3
Zeng, J.4
Ding, D.5
Carstens, R.P.6
Cong, Y.7
Xu, X.8
Guo, W.9
-
23
-
-
84977621648
-
The Arkadia-ESRP2 axis suppresses tumor progression: Analyses in clear-cell renal cell carcinoma
-
Mizutani A, Koinuma D, Seimiya H, Miyazono K (2015) The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma. Oncogene. doi:10.1038/onc2015.412
-
(2015)
Oncogene
-
-
Mizutani, A.1
Koinuma, D.2
Seimiya, H.3
Miyazono, K.4
-
25
-
-
84941737633
-
A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells
-
Preca BT, Bajdak K, Mock K, Sundararajan V, Pfannstiel J, Maurer J, Wellner U, Hopt UT, Brummer T, Brabletz S, Brabletz T, Stemmler MP (2015) A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. Int J Cancer 137:2566-2577
-
(2015)
Int J Cancer
, vol.137
, pp. 2566-2577
-
-
Preca, B.T.1
Bajdak, K.2
Mock, K.3
Sundararajan, V.4
Pfannstiel, J.5
Maurer, J.6
Wellner, U.7
Hopt, U.T.8
Brummer, T.9
Brabletz, S.10
Brabletz, T.11
Stemmler, M.P.12
-
26
-
-
84867795377
-
Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial-mesenchymal transition
-
Reinke LM, Xu Y, Cheng C (2012) Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial-mesenchymal transition. J Biol Chem 287:36435-36442
-
(2012)
J Biol Chem
, vol.287
, pp. 36435-36442
-
-
Reinke, L.M.1
Xu, Y.2
Cheng, C.3
-
27
-
-
0034659739
-
Rac1 in human breast cancer: Overexpression, mutation analysis, and characterization of a new isoform, Rac1b
-
Schnelzer A, Prechtel D, Knaus U, Dehne K, Gerhard M, Graeff H, Harbeck N, Schmitt M, Lengyel E (2000) Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b. Oncogene 19:3013-3020
-
(2000)
Oncogene
, vol.19
, pp. 3013-3020
-
-
Schnelzer, A.1
Prechtel, D.2
Knaus, U.3
Dehne, K.4
Gerhard, M.5
Graeff, H.6
Harbeck, N.7
Schmitt, M.8
Lengyel, E.9
-
28
-
-
79951813692
-
TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition
-
Shirakihara T, Horiguchi K, Miyazawa K, Ehata S, Shibata T, Morita I, Miyazono K, Saitoh M (2011) TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition. EMBO J 30:783-795
-
(2011)
EMBO J
, vol.30
, pp. 783-795
-
-
Shirakihara, T.1
Horiguchi, K.2
Miyazawa, K.3
Ehata, S.4
Shibata, T.5
Morita, I.6
Miyazono, K.7
Saitoh, M.8
-
29
-
-
84884666662
-
Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases
-
Ueda J, Matsuda Y, Yamahatsu K, Uchida E, Naito Z, Korc M, Ishiwata T (2014) Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene 33:4485-4495
-
(2014)
Oncogene
, vol.33
, pp. 4485-4495
-
-
Ueda, J.1
Matsuda, Y.2
Yamahatsu, K.3
Uchida, E.4
Naito, Z.5
Korc, M.6
Ishiwata, T.7
-
30
-
-
84866320228
-
Complex changes in alternatice pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT)
-
Warzecha CC, Carstens RP (2012) Complex changes in alternatice pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT). Semin Cancer Biol 22:417-427
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 417-427
-
-
Warzecha, C.C.1
Carstens, R.P.2
-
31
-
-
61649087689
-
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
-
Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP (2009a) ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 33:591-601
-
(2009)
Mol Cell
, vol.33
, pp. 591-601
-
-
Warzecha, C.C.1
Sato, T.K.2
Nabet, B.3
Hogenesch, J.B.4
Carstens, R.P.5
-
32
-
-
77950552549
-
The epithelial splicing regulatory factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
-
Warzecha CC, Shen S, Xing Y, Carstens RP (2009b) The epithelial splicing regulatory factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol 6:546-562
-
(2009)
RNA Biol
, vol.6
, pp. 546-562
-
-
Warzecha, C.C.1
Shen, S.2
Xing, Y.3
Carstens, R.P.4
-
33
-
-
77957767273
-
An ESRP-regualted splicing programme is abrogated during the epithelial-mesenchymal transition
-
Warzecha CC, Jiang P, Amirikian K, Ditmmar KA, Lu H, Shen S, Guo W, Xing Y, Carstens RP (2010) An ESRP-regualted splicing programme is abrogated during the epithelial-mesenchymal transition. EMBO J 29:3286-3300
-
(2010)
EMBO J
, vol.29
, pp. 3286-3300
-
-
Warzecha, C.C.1
Jiang, P.2
Amirikian, K.3
Ditmmar, K.A.4
Lu, H.5
Shen, S.6
Guo, W.7
Xing, Y.8
Carstens, R.P.9
-
34
-
-
84881439613
-
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer
-
Werner S, Frey S, Riethdorf S, Schulze C, Alawi M, Kling L, Vafaizadeh V, Sauter G, Terracciano L, Schumacher U, Pantel K, Assmann V (2013) Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer. J Biol Chem 288:22993-23008
-
(2013)
J Biol Chem
, vol.288
, pp. 22993-23008
-
-
Werner, S.1
Frey, S.2
Riethdorf, S.3
Schulze, C.4
Alawi, M.5
Kling, L.6
Vafaizadeh, V.7
Sauter, G.8
Terracciano, L.9
Schumacher, U.10
Pantel, K.11
Assmann, V.12
-
35
-
-
84871312342
-
Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression
-
Xiang X, Deng Z, Zhuang X, Ju S, Mu J, Jiang H, Zhang L, Yan J, Miller D, Zhang HG (2012) Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression. PLoS One 7:e50781
-
(2012)
Plos One
, pp. 7
-
-
Xiang, X.1
Deng, Z.2
Zhuang, X.3
Ju, S.4
Mu, J.5
Jiang, H.6
Zhang, L.7
Yan, J.8
Miller, D.9
Zhang, H.G.10
-
36
-
-
84901746783
-
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
-
Xu Y, Gao XD, Lee JH, Huang H, Tan H, Ahn J, Reinke LM, Peter ME, Feng Y, Gius D, Siziopikou KP, Peng J, Xiao X, Cheng C (2014) Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing. Genes Dev 28:1191-1203
-
(2014)
Genes Dev
, vol.28
, pp. 1191-1203
-
-
Xu, Y.1
Gao, X.D.2
Lee, J.H.3
Huang, H.4
Tan, H.5
Ahn, J.6
Reinke, L.M.7
Peter, M.E.8
Feng, Y.9
Gius, D.10
Siziopikou, K.P.11
Peng, J.12
Xiao, X.13
Cheng, C.14
-
37
-
-
84863321158
-
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
-
Yae T, Tsuchihashi K, Ishimoto T, Motohara T, Yoshikawa M, Yoshida GJ, Wada T, Masuko T, Mogushi K, Tanaka H, Osawa T, Kanki Y, Minami T, Aburatani H, Ohmura M, Kubo A, Suematsu M, Takahashi K, Saya H, Nagano O (2012) Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun 3:883
-
(2012)
Nat Commun
, vol.3
, pp. 883
-
-
Yae, T.1
Tsuchihashi, K.2
Ishimoto, T.3
Motohara, T.4
Yoshikawa, M.5
Yoshida, G.J.6
Wada, T.7
Masuko, T.8
Mogushi, K.9
Tanaka, H.10
Osawa, T.11
Kanki, Y.12
Minami, T.13
Aburatani, H.14
Ohmura, M.15
Kubo, A.16
Suematsu, M.17
Takahashi, K.18
Saya, H.19
Nagano, O.20
more..
|