Cinnamaldehyde derivatives inhibit coxsackievirus B3-induced viral myocarditis

Biomolecules and Therapeutics

Volumn 25, Issue 3, 2017, Pages 279-287

  Li, Xiao Qiang ^a   Liu, Xiao Xiao ^a   Wang, Xue Ying ^a   Xie, Yan Hua ^a   Yang, Qian ^a   Liu, Xin Xin ^a   Ding, Yuan Yuan ^a   Cao, Wei ^a   Wang, Si Wang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anti inflammatory; Cinnamaldehyde; Coxsackievirus B3; Myocarditis

Indexed keywords

2 BROMO 3 (4 CHLOROPHENYL)ACRYLALDEHYDE; 2 BROMO 3 4 TOLYLACRYLALDEHYDE; 3 (4 CHLOROPHENYL)ACRYLALDEHYDE; 3 (4 METHOXYPHENYL)ACRYLALDEHYDE; 3 4 TOLYLACRYLALDEHYDE; ALPHA INTERFERON; CINNAMALDEHYDE DERIVATIVE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; COXSACKIEVIRUS B3; CYTOKINE RELEASE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL LINE; IN VIVO STUDY; MALE; MOUSE; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT; VIRUS MYOCARDITIS; VIRUS TITRATION;

EID: 85019027052     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2016.070     Document Type: Article

References (35)

1. Battistuzzi, G., Cacchi, S. and Fabrizi, G. (2003) An efficient palladium-catalyzed synthesis of cinnamaldehydes from acrolein diethyl acetal and aryl iodides and bromides. Org. Lett. 5, 777-780.
2. Beige, J., Weber, A., Engeli, S., Offermann, G., Distler, A. and Sharma, A. M. (1996) Angiotensinogen-M235T genotype and post-trans-plant hypertension. Nephrol. Dial. Transplant. 11, 1538-1541.
3. Blauwet, L. A. and Cooper, L. T. (2010) Myocarditis. Prog. Cardiovasc. Dis. 52, 274-288.
4. Cao, W., Xie, Y. H., Li, X. Q., Zhang, X. K., Chen, Y. T., Kang, R., Chen, X., Miao, S. and Wang, S. W. (2011) Burn-induced apoptosis of cardiomyocytes is survivin dependent and regulated by PI3K/Akt, p38 MAPK and ERK pathways. Basic Res. Cardiol. 106, 1207-1220.
5. Chen, R., Zhou, H., Beltran, J., Malellari, L. and Chang, S. L. (2005) Differential expression of cytokines in the brain and serum during endotoxin tolerance. J. Neuroimmunol. 163, 53-72.
6. Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T. and Lin, C. C. (2002) Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral Res. 55, 53-62.
7. Cooper, L. T., Jr. (2009) Myocarditis. N. Engl. J. Med. 360, 1526-1538.
8. De Logu, A., Loy, G., Pellerano, M. L., Bonsignore, L. and Schivo, M. L. (2000) Inactivation of HSV-1 and HSV-2 and prevention of cell-to-cell virus spread by Santolina insularis essential oil. Antiviral Res. 48, 177-185.
9. Dennert, R., Crijns, H. J. and Heymans, S. (2008) Acute viral myocarditis. Eur. Heart J. 29, 2073-2082.
10. Ding, Y., Qiu, L., Zhao, G., Xu, J. and Wang, S. (2010) Influence of cinnamaldehyde on viral myocarditis in mice. Am. J. Med. Sci. 340, 114-120.
11. Fabre, A. and Sheppard, M. N. (2006) Sudden adult death syndrome and other non-ischaemic causes of sudden cardiac death. Heart 92, 316-320.
12. Feldman, A. M. and McNamara, D. (2000) Myocarditis. N. Engl. J. Med. 343, 1388-1398.
13. Gu, Y. and Tian, S. K. (2012) Olefination reactions of phosphorus-sta-bilized carbon nucleophiles. Top. Curr. Chem. 327, 197-238.
14. Gui, J., Yue, Y., Chen, R., Xu, W. and Xiong, S. (2012) A20 (TNFAIP3) alleviates CVB3-induced myocarditis via inhibiting NF-κB signaling. PLoS ONE 7, e46515.
15. Hayashi, K., Imanishi, N., Kashiwayama, Y., Kawano, A., Terasawa, K., Shimada, Y. and Ochiai, H. (2007) Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo. Antiviral Res. 74, 1-8.
16. Jessup, M., Abraham, W. T., Casey, D. E., Feldman, A. M., Francis, G. S., Ganiats, T. G., Konstam, M. A., Mancini, D. M., Rahko, P. S., Silver, M. A., Stevenson, L. W. and Yancy, C. W. (2009) 2009 focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation 119, 1977-2016.
17. Kashimura, T., Kodama, M., Hotta, Y., Hosoya, J., Yoshida, K., Ozawa, T., Watanabe, R., Okura, Y., Kato, K., Hanawa, H., Kuwano, R. and Aizawa, Y. (2004) Spatiotemporal changes of coxsackievirus and adenovirus receptor in rat hearts during postnatal development and in cultured cardiomyocytes of neonatal rat. Virchows Arch. 444, 283-292.
18. Liu, P. P. and Mason, J. W. (2001) Advances in the understanding of myocarditis. Circulation 104, 1076-1082.
19. Mall, G., Klingel, K., Albrecht, M., Seemann, M., Rieger, P. and Kan-dolf, R. (1991) Natural history of Coxsackievirus B3-induced myocarditis in ACA/Sn mice: viral persistence demonstrated by quantitative in situ hybridization histochemistry. Eur. Heart J. 12 Suppl D, 121-123.
20. Matsumori, A., Crumpacker, C. S. and Abelmann, W. H. (1987) Prevention of viral myocarditis with recombinant human leukocyte interferon alpha A/D in a murine model. J. Am. Coll. Cardiol. 9, 1320-1325.
21. Matsumori, A., Tomioka, N. and Kawai, C. (1988) Protective effect of recombinant alpha interferon on coxsackievirus B3 myocarditis in mice. Am. Heart J. 115, 1229-1232.
22. Nishio, R., Matsumori, A., Shioi, T., Ishida, H. and Sasayama, S. (1999) Treatment of experimental viral myocarditis with interleukin-10. Circulation 100, 1102-1108.
23. Nordqvist, A., Bjorkelid, C., Andaloussi, M., Jansson, A. M., Mowbray, S. L., Karlen, A. and Larhed, M. (2011) Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors. J. Org. Chem. 76, 8986-8998.
24. Reed, L. J. and Muench, H. (1938) A simple method of estimating fifty per cent endpoints. Am. J. Epidemiol. 27, 493-497.
25. Schultz, J. C., Hilliard, A. A., Cooper, L. T., Jr. and Rihal, C. S. (2009) Diagnosis and treatment of viral myocarditis. Mayo Clin. Proc. 84, 1001-1009.
26. Seong, I. W., Choe, S. C. and Jeon, E. S. (2001) Fulminant coxsacki-eviral myocarditis. N. Engl. J. Med. 345, 379.
27. Shen, Y., Kan, Q. C., Xu, W., Chu, Y. W. and Xiong, S. D. (2009) Coxsackievirus B3 infection induced viral myocarditis by regulating the expression pattern of chemokines in cardiac myocytes. Iran. J. Allergy Asthma Immunol. 8, 1-9.
28. Swedberg, K., Cleland, J., Dargie, H., Drexler, H., Follath, F., Komajda, M., Tavazzi, L., Smiseth, O. A., Gavazzi, A., Haverich, A., Hoes, A., Jaarsma, T., Korewicki, J., Levy, S., Linde, C., Lopez-Sendon, J. L., Nieminen, M. S., Pierard, L. and Remme, W. J.; Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology (2005) Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The task force for the diagnosis and treatment of chronic heart failure of the European Society of Cardiology. Eur. Heart J. 26, 1115-1140.
29. van Staden, L. F., Gravestock, D. and Ager, D. J. (2002) New developments in the Peterson olefination reaction. Chem. Soc. Rev. 31, 195-200.
30. Wang, Y. F., Wang, X. Y., Ren, Z., Qian, C. W., Li, Y. C., Kaio, K., Wang, Q. D., Zhang, Y., Zheng, L. Y., Jiang, J. H., Yang, C. R., Liu, Q., Zhang, Y. J. and Wang, Y. F. (2009) Phyllaemblicin B inhibits Coxsackie virus B3 induced apoptosis and myocarditis. Antiviral Res. 84, 150-158.
31. 2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice. Am. J. Physiol. Heart Circ. Physiol. 293, H69-H76.
32. Youn, H. S., Lee, J. K., Choi, Y. J., Saitoh, S. I., Miyake, K., Hwang, D. H. and Lee, J. Y. (2008) Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization. Biochem. Pharmacol. 75, 494-502.
33. Yuan, J., Bucher, J. R., Goehl, T. J., Dieter, M. P. and Jameson, C. W. (1992) Quantitation of cinnamaldehyde and cinnamic acid in blood by HPLC. J. Anal. Toxicol. 16, 359-362.
34. Zhang, Y., Cao, W., Xie, Y. H., Yang, Q., Li, X. Q., Liu, X. X. and Wang, S. W. (2012) The comparison of α-bromo-4-chlorocinnamaldehyde and cinnamaldehyde on coxsackie virus B3-induced myocarditis and their mechanisms. Int. Immunopharmacol. 14, 107-113.
35. Zhao, H., Xie, Y., Yang, Q., Cao, Y., Tu, H., Cao, W. and Wang, S. (2014) Pharmacokinetic study of cinnamaldehyde in rats by GC-MS after oral and intravenous administration. J. Pharm. Biomed. Anal. 89, 150-157.