Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on the growth of influenza A/PR/8 virus in vitro and in vivo

Antiviral Research

Volumn 74, Issue 1, 2007, Pages 1-8

  Hayashi, K ^a   Imanishi, N ^b   Kashiwayama, Y ^b   Kawano, A ^b   Terasawa, K ^a,b   Shimada, Y ^b   Ochiai, H ^b  

^a CHIBA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cinnamaldehyde; Influenza; Protein synthesis; Survival rate

Indexed keywords

CINNAMALDEHYDE; ESSENTIAL OIL; PLANT EXTRACT; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CINNAMON; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA; INFLUENZA VIRUS A; INOCULATION; KIDNEY CELL; LUNG INFECTION; LUNG LAVAGE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RESPIRATORY TRACT INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; VIROGENESIS; VIRUS INHIBITION; VIRUS PNEUMONIA;

ACROLEIN; ADMINISTRATION, INHALATION; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIVIRAL AGENTS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CHICK EMBRYO; CINNAMOMUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA B VIRUS; MICE; MICROBIAL SENSITIVITY TESTS; ORTHOMYXOVIRIDAE INFECTIONS; VIRAL PROTEINS;

CINNAMOMI; MUS;

EID: 33847635652     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.01.003     Document Type: Article

References (24)

1. Akaike T., Noguchi Y., Ijiri S., Setoguchi K., Suga M., Zheng Y.M., Dietzschold B., and Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 2448-2453
2. Chang S.T., Chen P.F., and Chang S.C. Antibacterial activity of leaf essential oils and their constituents from Cinnamomum osmophloeum. J. Ethnopharmacol. 77 (2001) 123-127
3. Cheung C., Hotchkiss S.A., and Pease C.K. Cinnamic compound metabolism in human skin and the role metabolism may play in determining relative sensitisation potency. J. Dermatol. Sci. 31 (2003) 9-19
4. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
5. Hey A.J. The virus genome and its replication. In: Nicholson K.G., Webster R.G., and Hey A.J. (Eds). Textbook of Influenza (1998), Blackwell Science, London 43-53
6. Imanishi N., Andoh T., Mantani N., Sakai S., Terasawa K., Shimada Y., Sato M., Katada Y., Ueda K., and Ochiai H. Macrophage-mediated inhibitory effect of Zingiber officinale Rosc, a traditional oriental herbal medicine, on the growth of influenza A/Aichi/2/68 virus. Am. J. Chin. Med. 34 (2006) 157-169
7. Ka H., Park H.J., Jung H.J., Choi J.W., Cho K.S., Ha J., and Lee K.T. Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells. Cancer Lett. 196 (2003) 143-152
8. Koo B.S., Lee S.I., Ha J.H., and Lee D.U. Inhibitory effects of the essential oil from SuHeXiang Wan on the central nervous system after inhalation. Biol. Pharm. Bull. 27 (2004) 515-519
9. Kurokawa M., Ochiai H., Nakajima K., and Niwayama S. Inhibitory effect of protein kinase C inhibitor on the replication of influenza type A virus. J. Gen. Virol. 71 (1990) 2149-2155
10. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
11. Lee H.S., Kim B.S., and Kim M.K. Suppression effect of Cinnamomum cassia bark-derived component on nitric oxide synthase. J. Agric. Food Chem. 50 (2002) 7700-7703
12. Mantani N., Andoh T., Kawamata H., Terasawa K., and Ochiai H. Inhibitory effect of Ephedrae herba, an oriental traditional medicine, on the growth of influenza A/PR/8 virus in MDCK cells. Antiviral. Res. 44 (1999) 193-200
13. Mantani N., Imanishi N., Kawamata H., Terasawa K., and Ochiai H. Inhibitory effect of (+)-catechin on the growth of influenza A/PR/8 virus in MDCK cells. Planta Med. 67 (2001) 240-243
14. Moon K.H., and Pack M.Y. Cytotoxicity of cinnamic aldehyde on leukemia L1210 cells. Drug Chem. Toxicol. 6 (1983) 521-535
15. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
16. National Toxicology Program. NTP toxicology and carcinogenesis studies of trans-cinnamaldehyde (CAS No. 14371-10-9) in F344/N rats and B6C3F1 mice (feed studies). Natl. Toxicol. Program Tech. Rep. Ser. 514 (2004) 1-281
17. Ochiai H., Sakai S., Hirabayashi T., Shimizu Y., and Terasawa K. Inhibitory effect of bafilomycin A1, a specific inhibitor of vacuolar-type proton pump, on the growth of influenza A and B viruses in MDCK cells. Antiviral. Res. 27 (1995) 425-430
18. Prime G., Ebner S., and Marin-Grez M. Reverse transcriptase-polymerase chain reaction study of anion exchanger-2 in canine tissues and different Madin-Darby canine kidney cell types. Kidney Int. 67 (1998) S171-S173
19. Sakai S., Kawamata H., Mantani N., Kogure T., Shimada Y., Terasawa K., Sakai T., Imanishi N., and Ochiai H. Therapeutic effect of anti-macrophage inflammatory protein 2 antibody on influenza virus-induced pneumonia in mice. J. Virol. 74 (2000) 2472-2476
20. Sapienza P.P., Ikeda G.J., Warr P.I., Plummer S.L., Dailey R.E., and Lin C.S. Tissue distribution and excretion of 14 C-labelled cinnamic aldehyde following single and multiple oral administration in male Fischer 344 rats. Food Chem. Toxicol. 31 (1993) 253-261
21. Tobita K. Permanent canine kidney (MDCK) cells for isolation and plaque assay of influenza B viruses. Med. Microbiol. Immunol. 162 (1975) 23-27
22. Vabret A., Sapin G., Lezin B., Mosnier A., Cohen J.M., Burnouf L., Petitjean J., Gouarin S., Campet M., and Freymuth F. Comparison of three non-nested RT-PCR for the detection of influenza A viruses. J. Clin. Virol. 17 (2000) 167-175
23. Yamada K., Mimaki Y., and Sashida Y. Effects of inhaling the vapor of Lavandula burnatii super-derived essential oil and linalool on plasma adrenocorticotropic hormone (ACTH), catecholamine and gonadotropin levels in experimental menopausal female rats. Biol. Pharm. Bull. 28 (2005) 378-379
24. Yuan J.H., Dieter M.P., Bucher J.R., and Jameson C.W. Toxicokinetics of cinnamaldehyde in F344 rats. Food Chem. Toxicol. 30 (1992) 997-1004