-
1
-
-
84919848147
-
Hepatitis B virus infection
-
Trepo C, Chan HL, Lok A. Hepatitis B virus infection. Lancet 2014;384:2053-2063.
-
(2014)
Lancet
, vol.384
, pp. 2053-2063
-
-
Trepo, C.1
Chan, H.L.2
Lok, A.3
-
2
-
-
84933182063
-
Re-evaluation of hepatitis B virus clinical phases by systems biology identifies unappreciated roles for the innate immune response and B cells
-
Vanwolleghem T, Hou J, van Oord G, Andeweg AC, Osterhaus AD, Pas SD, et al. Re-evaluation of hepatitis B virus clinical phases by systems biology identifies unappreciated roles for the innate immune response and B cells. Hepatology 2015;62:87-100.
-
(2015)
Hepatology
, vol.62
, pp. 87-100
-
-
Vanwolleghem, T.1
Hou, J.2
van Oord, G.3
Andeweg, A.C.4
Osterhaus, A.D.5
Pas, S.D.6
-
3
-
-
84949089603
-
A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
-
Buch S, Stickel F, Trepo E, Way M, Herrmann A, Nischalke HD, et al. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat Genet 2015;47:1443-1448.
-
(2015)
Nat Genet
, vol.47
, pp. 1443-1448
-
-
Buch, S.1
Stickel, F.2
Trepo, E.3
Way, M.4
Herrmann, A.5
Nischalke, H.D.6
-
4
-
-
84964334172
-
The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent
-
e6
-
Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, et al. The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent. Gastroenterology 2016;150:1219-1230.e6.
-
(2016)
Gastroenterology
, vol.150
, pp. 1219-1230
-
-
Mancina, R.M.1
Dongiovanni, P.2
Petta, S.3
Pingitore, P.4
Meroni, M.5
Rametta, R.6
-
5
-
-
85004009110
-
The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans
-
Luukkonen PK, Zhou Y, Hyotylainen T, Leivonen M, Arola J, Orho-Melander M, et al. The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans. J Hepatol 2016;65:1263-1265.
-
(2016)
J Hepatol
, vol.65
, pp. 1263-1265
-
-
Luukkonen, P.K.1
Zhou, Y.2
Hyotylainen, T.3
Leivonen, M.4
Arola, J.5
Orho-Melander, M.6
-
6
-
-
84987829315
-
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C
-
Thabet K, Asimakopoulos A, Shojaei M, Romero-Gomez M, Mangia A, Irving WL, et al. MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. Nat Commun 2016;7:12757.
-
(2016)
Nat Commun
, vol.7
, pp. 12757
-
-
Thabet, K.1
Asimakopoulos, A.2
Shojaei, M.3
Romero-Gomez, M.4
Mangia, A.5
Irving, W.L.6
-
7
-
-
57649171085
-
Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils
-
Gijon MA, Riekhof WR, Zarini S, Murphy RC, Voelker DR. Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. J Biol Chem 2008;283:30235-30245.
-
(2008)
J Biol Chem
, vol.283
, pp. 30235-30245
-
-
Gijon, M.A.1
Riekhof, W.R.2
Zarini, S.3
Murphy, R.C.4
Voelker, D.R.5
-
8
-
-
58849110405
-
Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer
-
Serini S, Piccioni E, Merendino N, Calviello G. Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer. Apoptosis 2009;14:135-152.
-
(2009)
Apoptosis
, vol.14
, pp. 135-152
-
-
Serini, S.1
Piccioni, E.2
Merendino, N.3
Calviello, G.4
-
9
-
-
21044445452
-
Apoptosis: a mechanism of acute and chronic liver injury
-
Guicciardi ME, Gores GJ. Apoptosis: a mechanism of acute and chronic liver injury. Gut 2005;54:1024-1033.
-
(2005)
Gut
, vol.54
, pp. 1024-1033
-
-
Guicciardi, M.E.1
Gores, G.J.2
-
10
-
-
0038108918
-
Amplification mechanisms of inflammation: Paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A(2) is regulated by cytosolic phospholipase A(2)-derived hydroperoxyeicosatetraenoic acid
-
Balboa MA, Perez R, Balsinde J. Amplification mechanisms of inflammation: Paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A(2) is regulated by cytosolic phospholipase A(2)-derived hydroperoxyeicosatetraenoic acid. J Immunol 2003;171:989-994.
-
(2003)
J Immunol
, vol.171
, pp. 989-994
-
-
Balboa, M.A.1
Perez, R.2
Balsinde, J.3
-
11
-
-
34547145165
-
G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences
-
Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007;39:175-191.
-
(2007)
Behav Res Methods
, vol.39
, pp. 175-191
-
-
Faul, F.1
Erdfelder, E.2
Lang, A.G.3
Buchner, A.4
-
12
-
-
79958125953
-
Statistical Power Analysis for the Behavioral Sciences
-
Cohen, J. Statistical Power Analysis for the Behavioral Sciences. Percept Mot Skills 1988;67:1007-1007.
-
(1988)
Percept Mot Skills
, vol.67
, pp. 1007
-
-
Cohen, J.1
-
13
-
-
84884978594
-
Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B
-
Vigano M, Valenti L, Lampertico P, Facchetti F, Motta BM, D'Ambrosio R, et al. Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B. Hepatology 2013;58:1245-1252.
-
(2013)
Hepatology
, vol.58
, pp. 1245-1252
-
-
Vigano, M.1
Valenti, L.2
Lampertico, P.3
Facchetti, F.4
Motta, B.M.5
D'Ambrosio, R.6
-
14
-
-
70349240414
-
Chronic hepatitis B: update 2009
-
Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 2009;50:661-662.
-
(2009)
Hepatology
, vol.50
, pp. 661-662
-
-
Lok, A.S.1
McMahon, B.J.2
-
15
-
-
84916910477
-
Characteristics of adults in the hepatitis B research network in North America reflect their country of origin and hepatitis B virus genotype
-
Ghany MG, Perrillo R, Li R, Belle SH, Janssen HL, Terrault NA, et al. Characteristics of adults in the hepatitis B research network in North America reflect their country of origin and hepatitis B virus genotype. Clin Gastroenterol Hepatol 2015;13:183-192.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 183-192
-
-
Ghany, M.G.1
Perrillo, R.2
Li, R.3
Belle, S.H.4
Janssen, H.L.5
Terrault, N.A.6
-
16
-
-
85006355372
-
Determination of hepatitis B phenotype using biochemical and serological markers
-
Dec 5., [Epub ahead of print]
-
Di Bisceglie AM, Lombardero M, Teckman J, Roberts L, Janssen HL, Belle SH, Hoofnagle JH; Hepatitis B Research Network (HBRN). Determination of hepatitis B phenotype using biochemical and serological markers. J Viral Hepat 2016 Dec 5. doi: 10.1111/jvh.12643. [Epub ahead of print]
-
(2016)
J Viral Hepat
-
-
Di Bisceglie, A.M.1
Lombardero, M.2
Teckman, J.3
Roberts, L.4
Janssen, H.L.5
Belle, S.H.6
Hoofnagle, J.H.7
-
17
-
-
84976496508
-
Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes
-
Eslam M, Mangia A, Berg T, Chan HL, Irving WL, Dore GJ, et al.; International Liver Disease Genetics Consortium. Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes. Hepatology 2016;64:34-36.
-
(2016)
Hepatology
, vol.64
, pp. 34-36
-
-
Eslam, M.1
Mangia, A.2
Berg, T.3
Chan, H.L.4
Irving, W.L.5
Dore, G.J.6
-
18
-
-
0029778988
-
An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group
-
Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 1996;24:289-293.
-
(1996)
Hepatology
, vol.24
, pp. 289-293
-
-
Bedossa, P.1
Poynard, T.2
-
19
-
-
84924362729
-
Interferon-lambda rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease
-
Eslam M, Hashem AM, Leung R, Romero-Gomez M, Berg T, Dore GJ, et al. Interferon-lambda rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nat Commun 2015;6:6422.
-
(2015)
Nat Commun
, vol.6
, pp. 6422
-
-
Eslam, M.1
Hashem, A.M.2
Leung, R.3
Romero-Gomez, M.4
Berg, T.5
Dore, G.J.6
-
20
-
-
84954366506
-
FibroGENE: A gene-based model for staging liver fibrosis
-
Eslam M, Hashem AM, Romero-Gomez M, Berg T, Dore GJ, Mangia A, et al. FibroGENE: A gene-based model for staging liver fibrosis. J Hepatol 2016;64:390-398.
-
(2016)
J Hepatol
, vol.64
, pp. 390-398
-
-
Eslam, M.1
Hashem, A.M.2
Romero-Gomez, M.3
Berg, T.4
Dore, G.J.5
Mangia, A.6
-
21
-
-
84904622632
-
IFNL3 polymorphisms predict response to therapy in chronic hepatitis C genotype 2/3 infection
-
Eslam M, Leung R, Romero-Gomez M, Mangia A, Irving WL, Sheridan D, et al. IFNL3 polymorphisms predict response to therapy in chronic hepatitis C genotype 2/3 infection. J Hepatol 2014;61:235-241.
-
(2014)
J Hepatol
, vol.61
, pp. 235-241
-
-
Eslam, M.1
Leung, R.2
Romero-Gomez, M.3
Mangia, A.4
Irving, W.L.5
Sheridan, D.6
-
22
-
-
66049157487
-
Signals of recent positive selection in a worldwide sample of human populations
-
Pickrell JK, Coop G, Novembre J, Kudaravalli S, Li JZ, Absher D, et al. Signals of recent positive selection in a worldwide sample of human populations. Genome Res 2009;19:826-837.
-
(2009)
Genome Res
, vol.19
, pp. 826-837
-
-
Pickrell, J.K.1
Coop, G.2
Novembre, J.3
Kudaravalli, S.4
Li, J.Z.5
Absher, D.6
-
23
-
-
84858779229
-
HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
-
Ward LD, Kellis M. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res 2012;40:D930-D934.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D930-D934
-
-
Ward, L.D.1
Kellis, M.2
-
24
-
-
70350199624
-
The impact of handling missing data on alcohol consumption estimates in the UK women cohort study
-
Nur U, Longford NT, Cade JE, Greenwood DC. The impact of handling missing data on alcohol consumption estimates in the UK women cohort study. Eur J Epidemiol 2009;24:589-595.
-
(2009)
Eur J Epidemiol
, vol.24
, pp. 589-595
-
-
Nur, U.1
Longford, N.T.2
Cade, J.E.3
Greenwood, D.C.4
-
26
-
-
84943171338
-
A global reference for human genetic variation
-
1000 Genomes Project Consortium, Auton A, Brooks LD, Durbin RM, Garrison EP, Kang HM, et al. A global reference for human genetic variation. Nature 2015;526:68-74.
-
(2015)
Nature
, vol.526
, pp. 68-74
-
-
Auton, A.1
Brooks, L.D.2
Durbin, R.M.3
Garrison, E.P.4
Kang, H.M.5
-
27
-
-
79959554057
-
Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C
-
Trepo E, Pradat P, Potthoff A, Momozawa Y, Quertinmont E, Gustot T, et al. Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C. Hepatology 2011;54:60-69.
-
(2011)
Hepatology
, vol.54
, pp. 60-69
-
-
Trepo, E.1
Pradat, P.2
Potthoff, A.3
Momozawa, Y.4
Quertinmont, E.5
Gustot, T.6
-
28
-
-
77950607738
-
Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
-
Valenti L, Al-Serri A, Daly AK, Galmozzi E, Rametta R, Dongiovanni P, et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2010;51:1209-1217.
-
(2010)
Hepatology
, vol.51
, pp. 1209-1217
-
-
Valenti, L.1
Al-Serri, A.2
Daly, A.K.3
Galmozzi, E.4
Rametta, R.5
Dongiovanni, P.6
-
29
-
-
84856691720
-
Disruption of Smad4 impairs TGF-beta/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro
-
Meng XM, Huang XR, Xiao J, Chung AC, Qin W, Chen HY, Lan HY. Disruption of Smad4 impairs TGF-beta/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro. Kidney Int 2012;81:266-279.
-
(2012)
Kidney Int
, vol.81
, pp. 266-279
-
-
Meng, X.M.1
Huang, X.R.2
Xiao, J.3
Chung, A.C.4
Qin, W.5
Chen, H.Y.6
Lan, H.Y.7
-
30
-
-
0035112148
-
The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis
-
Lee DK, Park SH, Yi Y, Choi SG, Lee C, Parks WT, et al. The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis. Genes Dev 2001;15:455-466.
-
(2001)
Genes Dev
, vol.15
, pp. 455-466
-
-
Lee, D.K.1
Park, S.H.2
Yi, Y.3
Choi, S.G.4
Lee, C.5
Parks, W.T.6
-
32
-
-
84884153932
-
Fatty acid remodeling in cellular glycerophospholipids following the activation of human T cells
-
Robichaud PP, Boulay K, Munganyiki JE, Surette ME. Fatty acid remodeling in cellular glycerophospholipids following the activation of human T cells. J Lipid Res 2013;54:2665-2677.
-
(2013)
J Lipid Res
, vol.54
, pp. 2665-2677
-
-
Robichaud, P.P.1
Boulay, K.2
Munganyiki, J.E.3
Surette, M.E.4
-
33
-
-
78651459446
-
Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell line
-
Notarnicola M, Messa C, Refolo MG, Tutino V, Miccolis A, Caruso MG. Polyunsaturated fatty acids reduce fatty acid synthase and hydroxy-methyl-glutaryl CoA-reductase gene expression and promote apoptosis in HepG2 cell line. Lipids Health Dis 2011;10:10.
-
(2011)
Lipids Health Dis
, vol.10
, pp. 10
-
-
Notarnicola, M.1
Messa, C.2
Refolo, M.G.3
Tutino, V.4
Miccolis, A.5
Caruso, M.G.6
-
34
-
-
84925937811
-
Alterations of protein expression in serum of infants with intrauterine growth restriction and different gestational ages
-
Ruis-Gonzalez MD, Canete MD, Gomez-Chaparro JL, Abril N, Canete R, Lopez-Barea J. Alterations of protein expression in serum of infants with intrauterine growth restriction and different gestational ages. J Proteomics 2015;119:169-182.
-
(2015)
J Proteomics
, vol.119
, pp. 169-182
-
-
Ruis-Gonzalez, M.D.1
Canete, M.D.2
Gomez-Chaparro, J.L.3
Abril, N.4
Canete, R.5
Lopez-Barea, J.6
-
35
-
-
67651158857
-
Liver steatosis in patients with chronic hepatitis B infection: host and viral risk factors
-
Minakari M, Molaei M, Shalmani HM, Mohammad Alizadeh AH, Jazi AH, Naderi N, et al. Liver steatosis in patients with chronic hepatitis B infection: host and viral risk factors. Eur J Gastroenterol Hepatol 2009;21:512-516.
-
(2009)
Eur J Gastroenterol Hepatol
, vol.21
, pp. 512-516
-
-
Minakari, M.1
Molaei, M.2
Shalmani, H.M.3
Mohammad Alizadeh, A.H.4
Jazi, A.H.5
Naderi, N.6
-
36
-
-
84887440152
-
LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition
-
Rong X, Albert CJ, Hong C, Duerr MA, Chamberlain BT, Tarling EJ, et al. LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition. Cell Metabolism 2013;18:685-697.
-
(2013)
Cell Metabolism
, vol.18
, pp. 685-697
-
-
Rong, X.1
Albert, C.J.2
Hong, C.3
Duerr, M.A.4
Chamberlain, B.T.5
Tarling, E.J.6
-
37
-
-
84964841400
-
Small Intestine but Not Liver Lysophosphatidylcholine acyltransferase 3 (Lpcat3) deficiency has a dominant effect on plasma lipid metabolism
-
Kabir I, Li Z, Bui HH, Kuo MS, Gao G, Jiang XC. Small Intestine but Not Liver Lysophosphatidylcholine acyltransferase 3 (Lpcat3) deficiency has a dominant effect on plasma lipid metabolism. J Biol Chem 2016;291:7651-7660.
-
(2016)
J Biol Chem
, vol.291
, pp. 7651-7660
-
-
Kabir, I.1
Li, Z.2
Bui, H.H.3
Kuo, M.S.4
Gao, G.5
Jiang, X.C.6
-
38
-
-
80052386721
-
Hepatic steatosis in hepatitis B virus infected patients: meta-analysis of risk factors and comparison with hepatitis C infected patients
-
Machado MV, Oliveira AG, Cortez-Pinto H. Hepatic steatosis in hepatitis B virus infected patients: meta-analysis of risk factors and comparison with hepatitis C infected patients. J Gastroenterol Hepatol 2011;26:1361-1367.
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 1361-1367
-
-
Machado, M.V.1
Oliveira, A.G.2
Cortez-Pinto, H.3
-
39
-
-
34548738566
-
Population genomics of human gene expression
-
Stranger BE, Nica AC, Forrest MS, Dimas A, Bird CP, Beazley C, et al. Population genomics of human gene expression. Nat Genet 2007;39:1217-1224.
-
(2007)
Nat Genet
, vol.39
, pp. 1217-1224
-
-
Stranger, B.E.1
Nica, A.C.2
Forrest, M.S.3
Dimas, A.4
Bird, C.P.5
Beazley, C.6
-
40
-
-
33846631884
-
Common genetic variants account for differences in gene expression among ethnic groups
-
Spielman RS, Bastone LA, Burdick JT, Morley M, Ewens WJ, Cheung VG. Common genetic variants account for differences in gene expression among ethnic groups. Nat Genet 2007;39:226-231.
-
(2007)
Nat Genet
, vol.39
, pp. 226-231
-
-
Spielman, R.S.1
Bastone, L.A.2
Burdick, J.T.3
Morley, M.4
Ewens, W.J.5
Cheung, V.G.6
-
42
-
-
79957993750
-
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue
-
Innocenti F, Cooper GM, Stanaway IB, Gamazon ER, Smith JD, Mirkov S, et al. Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. PLoS Genet 2011;7:e1002078.
-
(2011)
PLoS Genet
, vol.7
-
-
Innocenti, F.1
Cooper, G.M.2
Stanaway, I.B.3
Gamazon, E.R.4
Smith, J.D.5
Mirkov, S.6
|