Autocrine lysophosphatidic acid signaling activates ?-catenin and promotes lung allograft fibrosis

Journal of Clinical Investigation

Volumn 127, Issue 4, 2017, Pages 1517-1530

  Cao, Pengxiu ^a   Aoki, Yoshiro ^a   Badri, Linda ^a   Walker, Natalie M ^a   Manning, Casey M ^a   Lagstein, Amir ^b   Fearon, Eric R ^c   Lama, Vibha N ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOTAXIN; BETA CATENIN; LYSOPHOSPHATIDIC ACID; NUCLEAR FACTOR OF ACTIVATED T CELL 2; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; ALKYLGLYCEROPHOSPHOETHANOLAMINE PHOSPHODIESTERASE; COLLAGEN; CTNNB1 PROTEIN, HUMAN; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHOLIPID; NFATC2 PROTEIN, HUMAN; PHOSPHODIESTERASE;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BRONCHIOLITIS OBLITERANS; CONTROLLED STUDY; CYTOKINE RELEASE; FIBROGENESIS; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; IN VIVO STUDY; LUNG FIBROSIS; LUNG TRANSPLANTATION; MALE; MESENCHYME CELL; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DBA MOUSE; FEMALE; GRAFT REJECTION; LUNG; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ALLOGRAFTS; ANIMALS; AUTOCRINE COMMUNICATION; BETA CATENIN; BRONCHIOLITIS OBLITERANS; CELLS, CULTURED; COLLAGEN; FEMALE; GRAFT REJECTION; HUMANS; LUNG; LUNG TRANSPLANTATION; LYSOPHOSPHOLIPIDS; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; NFATC TRANSCRIPTION FACTORS; PHOSPHORIC DIESTER HYDROLASES; PULMONARY FIBROSIS; RECEPTORS, LYSOPHOSPHATIDIC ACID; TRANSCRIPTIONAL ACTIVATION;

EID: 85018686239     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI88896     Document Type: Article

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