Autotaxin-LPA axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3-dependent PKC/GSK3β/β-catenin and PKC/Rho GTPase pathways

Stem Cells

Volumn 33, Issue 3, 2015, Pages 819-832

  Ryu, Jung Min ^a   Han, Ho Jae ^a  

^a Seoul National University   (South Korea)

Author keywords

Adherent junction; Autotaxin; Cytoskeleton rearrangement; Lysophosphatidic acid; Migration; Wound healing

Indexed keywords

AUTOTAXIN; BETA CATENIN; CADHERIN; CADHERIN 1; F ACTIN; GLYCOGEN SYNTHASE KINASE 3BETA; LYSOPHOSPHATIDIC ACID; PERTUSSIS TOXIN; PROTEIN CDC42; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; ALKYLGLYCEROPHOSPHOETHANOLAMINE PHOSPHODIESTERASE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHOLIPID; PHOSPHODIESTERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL DISRUPTION; CELL MIGRATION; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WOUND HEALING; ANIMAL; CELL CULTURE; CELL JUNCTION; CELL MOTION; CYTOLOGY; CYTOSKELETON; GENETIC TRANSFECTION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; MESENCHYMAL STROMA CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADHERENS JUNCTIONS; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CYTOSKELETON; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LYSOPHOSPHOLIPIDS; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED ICR; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, LYSOPHOSPHATIDIC ACID; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84923219594     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1882     Document Type: Article

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