iPSC-Derived Regulatory Dendritic Cells Inhibit Allograft Rejection by Generating Alloantigen-Specific Regulatory T Cells

Stem Cell Reports

Volumn 8, Issue 5, 2017, Pages 1174-1189

  Cai, Songjie ^a,b   Hou, Jiangang ^a,c   Fujino, Masayuki ^a,d   Zhang, Qi ^c   Ichimaru, Naotsugu ^b   Takahara, Shiro ^b   Araki, Ryoko ^e   Lu, Lina ^f   Chen, Ji Mei ^g   Zhuang, Jian ^g   Zhu, Ping ^g   Li, Xiao Kang ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c FUDAN UNIVERSITY   (China)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^e NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^f LERNER RESEARCH INSTITUTE   (United States)

^g GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

antigen specific tolerance; iPSC; murine cardiac allotransplant; regulatory dendritic cells; regulatory T cells; TGF 1

Indexed keywords

ALLOANTIGEN; ARG 1 PROTEIN; B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GRANZYME B; HO 1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PERFORIN; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; GRAFT REJECTION; GRAFT SURVIVAL; HEART GRAFT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INDUCED PLURIPOTENT STEM CELL; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SPLEEN CELL; VACCINATION; ALLOGRAFT; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CBA MOUSE; CELL CULTURE; CELL TRANSPLANTATION; CYTOLOGY; IMMUNOLOGY; IMMUNOTHERAPY; MALE; PROCEDURES; TRANSPLANTATION;

ALLOGRAFTS; ANIMALS; CELL TRANSPLANTATION; CELLS, CULTURED; DENDRITIC CELLS; GRAFT REJECTION; IMMUNOTHERAPY; INDUCED PLURIPOTENT STEM CELLS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED CBA; T-LYMPHOCYTES, REGULATORY;

EID: 85018575293     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2017.03.020     Document Type: Article

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