Prevention of advanced glycation end-products formation in diabetic rats through beta-cell modulation by Aegle marmelos

BMC Complementary and Alternative Medicine

Volumn 17, Issue 1, 2017, Pages

  Hafizur, Rahman M ^a   Momin, Shahrukh ^a   Fatima, Noor ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Advanced glycation end products; Aegle marmelos; Eugenol; Immunohistochemistry; Insulin secretion; cell function

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AEGLE MARMELOS EXTRACT; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CREATININE; EUGENOL; GLIBENCLAMIDE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UREA; ANTIDIABETIC AGENT; ANTIOXIDANT; GLUCOSE BLOOD LEVEL; PLANT EXTRACT;

AEGLE MARMELOS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIGLYCATION ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; BOWMAN CAPSULE; CELL FUNCTION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DRUG ACTIVITY; DRUG EFFICACY; FEMALE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HISTOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; KIDNEY TUBULE BASEMENT MEMBRANE; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; AEGLE; ANIMAL; BLOOD; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; FRUIT; KIDNEY; METABOLISM; PHYTOTHERAPY; WISTAR RAT;

AEGLE; ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EUGENOL; FEMALE; FRUIT; GLYCOSYLATION END PRODUCTS, ADVANCED; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; KIDNEY; MALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS, WISTAR;

EID: 85018463895     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-017-1743-y     Document Type: Article

References (34)

1. Singh R, Barden A, Mori T, Beilin L. Advanced glycation end-products: a review. Diabetologia. 2001;44:129-46.
2. Ahmed N, Babaei-Jadidi R, Howell S, Thornalley P, Beisswenger P. Glycated and Oxidized Protein Degradation Products Are Indicators of Fasting and Postprandial Hyperglycemia in Diabetes. Diabetes Care. 2005;28:2465-71.
3. Freedman BI, Wuerth JP, Cartwright K, Bain RP, Dippe S, Hershon K, Mooradian AD, Spinowitz BS. Design and baseline characteristics for the aminoguanidine clinical trial in overt type 2 diabetic nephropathy (ACTION II). Control Clin Trials. 1999;20:493-510.
4. Alam S, Ahsan A, Alam S. Newer insights in drugs inhibiting formation and accumulation of advanced glycation end products. J Biochem Tech. 2013;5:666-72.
5. Dikshit BBL, Dutt S. Preliminary chemical examination of Aegle marmelos or the Indian Bel. J Ind Chem Society. 1930;7:759-64.
6. Parmar C, Kaushal MK. Wild fruits of the Sub-Himalayan Region. New Delhi: Kalyani Publishers; 1982.
7. Suvimol C, Pranee A. Bioactive compounds of Thai bael fruit (Aegle marmelos (L.) Correa) as a valuable source for functional food ingredients. Int Food Res J. 2008;15:287-95.
8. Yadav NP, Chanotia CS. Phytochemical and pharmacological profile of leaves of Aegle marmelos L Corr. Pharm Rev. 2009:144-9.
9. Johnson M. Biochemical variation studies in Aegle marmelos L. Corr: a medicinally important plant. J Chem Pharm Res. 2010;2:454-62.
10. Maity P, Hansda D, Bandyopadhyay U, Mishra DK. x crude extracts and chemical constituents of Bael, Aegle marmelos (L.) Corr. Ind J Ext Biol. 2009;47:849-61.
11. Patel PK, Sahu J, Sahu L, Prajapati NK, Dubey BK. Aegle marmelos: A review on its medicinal properties. Int J Pharm Phytopharmacol Res. 2012;1:332-41.
12. Kumar KS, Ashish GR, Mony RS, Sundaresan A. Comparative evaluation of the antioxidant and antidiabetic activity of different parts of Aegle marmelos and its chemical profiling using HPLC and HPTLC technique. World J Pharm Pharm Sci. 2015;4:1107-21.
13. Kamalakkanan N, Rajadurai M, Prince PS. Effect of Aegle marmelos fruits on normal and streptozotocin-diabetic Wistar rats. J Med Food. 2003;6:93-8.
14. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-9.
15. Hafizur RM, Kabir N, Chishti S. Modulation of pancreatic β-cells in neonatally streptozotocin induced type 2 diabetic rats by the ethanolic extract of Momordica charantia fruit pulp. Nat Prod Res. 2011;25:353-67.
16. Hafizur RM, Kabir N, Chishti S. Asparagus officinalis extract controls blood glucose by improving insulin secretion and β-cell function in streptozotocin-induced type 2 diabetic rats. Br J Nutr. 2012;108:1586-95.
17. Siddiqui BS, Hasan M, Mairaj F, Mehmood I, Hafizur RM, Hameed A, Khan Shinwari Z. Two new compounds from the aerial parts of Bergenia himalaica Boriss and their antihyperglycemic effect in streptozotocin-nicotinamide induced diabetic rats. J Ethnopharmacol. 2014;152:561-7.
18. Hafizur RM, Hameed A, Shukrana M, Raza SA, Chishti S, Kabir N, Siddiqui RA. Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro. Phytomedicine. 2015;22:297-300.
19. Sachdewa A, Raina D, Srivastava AK, Khemani LD. Effect of Aegle marmelos and Hibiscus rosa sinensis leaf extract on glucose tolerance in glucose induced hyperglycemic rats (Charles foster). J Environ Biol. 2001;22:53-7.
20. Kamalakkannan N, Prince PS. The effect of Aegle marmelos fruit extract in streptozotocin diabetes: a histopathological study. J Herb Pharmacother. 2005;5:87-96.
21. Esmaeili MA, Zohari F, Sadeghi H. Antioxidant and protective effects of major flavonoids from Teucrium polium on beta-cell destruction in a model of streptozotocin-induced diabetes. Planta Med. 2009;75:1418-20.
22. Noumura E, Kashiwada A, Hosoda A, Nakamura K, Morishita H, Tsuno T, Taniguchi H. Synthesis of amide compounds of ferulic acid and their stimulatory effects on insulin secretion in vitro. Bioorg Med Chem. 2003;11:3807-13.
23. Fatima N, Hafizur RM, Hameed A, Ahmed S, Nisar M, Kabir N: Ellagic acid in Emblica officinalis exerts anti-diabetic activity through the action on β-cells of pancreas. Eur J Nutr. 2015. doi: 10.1007/s00394-015-1103-y.
24. Papaccio G, Mezzogiorno M. Morphological aspect of glucagon and somatostatin islet cells in diabetic biobreeding and low-dose streptozotocin-treated Wistar rats. Pancreas. 1989;4:289-94.
25. Pons P, Aoki A. Differential proliferation of somatostatin and glucagon cells in rat pancreatic islets submitted to different stimuli. Ann Anat. 1995;177:221-7.
26. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes. 2003;52:102-10.
27. Rahier J, Goebbels RM, Henquin JC. Cellular composition of the human diabetic pancreas. Diabetologia. 1983;24:366-71.
28. Berg TJ, Bangstad HJ, Torjesen PA, Osterby R, Bucala R, Hanssen KF. Advanced glycation end products in serum predict changes in the kidney morphology of patients with insulin-dependent diabetes mellitus. Metabolism. 1997;46:661-5.
29. Aso Y, Inukai T, Tayama K, Takemura Y. Serum concentrations of advanced glycation endproducts are associated with the development of atherosclerosis as well as diabetic microangiopathy in patients with type 2 diabetes. Acta Diabetol. 2000;37:87-92.
30. Verbeke P, Perichon M, Borot-Laloi C, Schaeverbeke J, Bakala H. Accumulation of advanced glycation endproducts in the rat nephron: link with circulating AGEs during aging. J Histochem Cytochem. 1997;45:1059-68.
31. Bendayan M. Immunocytochemical detection of advanced glycated endproducts in rat renal tissue as a function of age and diabetes. Kidney Int. 1998;54:438-47.
32. Kittl M, Beyreis M, Tumurkhuu M, Fürst J, Helm K, Pitschmann A, Gaisberger M, Glasl S, Ritter M, Jakab M. Quercetin stimulates insulin secretion and reduces the viability of rat INS-1 beta-cells. Cell Physiol Biochem. 2016;39:278-93.
33. Cervantes-Laurean D, Schramm DD, Jacobson EL, Halaweish I, Bruckner GG, Boissonneault GA. Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites. J Nutr Biochem. 2006;17:531-40.
34. Li X, Zheng T, Sang S, Lv L. Quercetin inhibits advanced glycation end product formation by trapping methylglyoxal and glyoxal. J Agric Food Chem. 2014;62:12152-8.