메뉴 건너뛰기




Volumn 66, Issue 3, 2017, Pages 896-907

Statins decrease the risk of decompensation in hepatitis B virus– and hepatitis C virus–related cirrhosis: A population-based study

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERFERON;

EID: 85018446169     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.29172     Document Type: Article
Times cited : (100)

References (38)
  • 1
    • 28844490547 scopus 로고    scopus 로고
    • Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies
    • D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217-231.
    • (2006) J Hepatol , vol.44 , pp. 217-231
    • D'Amico, G.1    Garcia-Tsao, G.2    Pagliaro, L.3
  • 2
    • 34547539830 scopus 로고    scopus 로고
    • Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis
    • Ripoll C, Groszmann R, Garcia-Tsao G, Grace N, Burroughs A, Planas R, et al. Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology 2007;133:481-488.
    • (2007) Gastroenterology , vol.133 , pp. 481-488
    • Ripoll, C.1    Groszmann, R.2    Garcia-Tsao, G.3    Grace, N.4    Burroughs, A.5    Planas, R.6
  • 3
    • 24744444714 scopus 로고    scopus 로고
    • A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
    • Liu S, Premont RT, Kontos CD, Zhu S, Rockey DC. A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension. Nat Med 2005;11:952-958.
    • (2005) Nat Med , vol.11 , pp. 952-958
    • Liu, S.1    Premont, R.T.2    Kontos, C.D.3    Zhu, S.4    Rockey, D.C.5
  • 4
    • 84926323391 scopus 로고    scopus 로고
    • Vascular pathobiology in chronic liver disease and cirrhosis—current status and future directions
    • Iwakiri Y, Shah V, Rockey DC. Vascular pathobiology in chronic liver disease and cirrhosis—current status and future directions. J Hepatol 2014;61:912-924.
    • (2014) J Hepatol , vol.61 , pp. 912-924
    • Iwakiri, Y.1    Shah, V.2    Rockey, D.C.3
  • 5
    • 34547469050 scopus 로고    scopus 로고
    • Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase
    • Trebicka J, Hennenberg M, Laleman W, Shelest N, Biecker E, Schepke M, et al. Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase. Hepatology 2007;46:242-253.
    • (2007) Hepatology , vol.46 , pp. 242-253
    • Trebicka, J.1    Hennenberg, M.2    Laleman, W.3    Shelest, N.4    Biecker, E.5    Schepke, M.6
  • 7
    • 1542317594 scopus 로고    scopus 로고
    • Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis
    • Zafra C, Abraldes JG, Turnes J, Berzigotti A, Fernandez M, Garca-Pagan JC, et al. Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis. Gastroenterology 2004;126:749-755.
    • (2004) Gastroenterology , vol.126 , pp. 749-755
    • Zafra, C.1    Abraldes, J.G.2    Turnes, J.3    Berzigotti, A.4    Fernandez, M.5    Garca-Pagan, J.C.6
  • 8
    • 84905580178 scopus 로고    scopus 로고
    • Statin use in patients with cirrhosis: a retrospective cohort study
    • Kumar S, Grace ND, Qamar AA. Statin use in patients with cirrhosis: a retrospective cohort study. Dig Dis Sci 2014;59:1958-1965.
    • (2014) Dig Dis Sci , vol.59 , pp. 1958-1965
    • Kumar, S.1    Grace, N.D.2    Qamar, A.A.3
  • 9
    • 84959470927 scopus 로고    scopus 로고
    • Statins are associated with a decreased risk of decompensation and death in veterans with hepatitis C-related compensated cirrhosis
    • Mohanty A, Tate JP, Garcia-Tsao G. Statins are associated with a decreased risk of decompensation and death in veterans with hepatitis C-related compensated cirrhosis. Gastroenterology 2016;150:430-440.
    • (2016) Gastroenterology , vol.150 , pp. 430-440
    • Mohanty, A.1    Tate, J.P.2    Garcia-Tsao, G.3
  • 10
    • 84966587156 scopus 로고    scopus 로고
    • Statins reduce the risk of cirrhosis and its decompensation in chronic hepatitis B patients: a nationwide cohort study
    • Huang YW, Lee CL, Yang SS, Fu SC, Chen YY, Wang TC, et al. Statins reduce the risk of cirrhosis and its decompensation in chronic hepatitis B patients: a nationwide cohort study. Am J Gastroenterol 2016;111:976-985.
    • (2016) Am J Gastroenterol , vol.111 , pp. 976-985
    • Huang, Y.W.1    Lee, C.L.2    Yang, S.S.3    Fu, S.C.4    Chen, Y.Y.5    Wang, T.C.6
  • 12
    • 84863115964 scopus 로고    scopus 로고
    • Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection
    • Tsan YT, Lee CH, Wang JD, Chen PC. Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection. J Clin Oncol 2012;30:623-630.
    • (2012) J Clin Oncol , vol.30 , pp. 623-630
    • Tsan, Y.T.1    Lee, C.H.2    Wang, J.D.3    Chen, P.C.4
  • 13
    • 84876516919 scopus 로고    scopus 로고
    • Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection
    • Tsan YT, Lee CH, Ho WC, Lin MH, Wang JD, Chen PC. Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection. J Clin Oncol 2013;31:1514-1521.
    • (2013) J Clin Oncol , vol.31 , pp. 1514-1521
    • Tsan, Y.T.1    Lee, C.H.2    Ho, W.C.3    Lin, M.H.4    Wang, J.D.5    Chen, P.C.6
  • 14
    • 84945437158 scopus 로고    scopus 로고
    • Statin use and the risk of cirrhosis development in patients with hepatitis C virus infection
    • Yang YH, Chen WC, Tsan YT, Chen MJ, Shih WT, Tsai YH, et al. Statin use and the risk of cirrhosis development in patients with hepatitis C virus infection. J Hepatol 2015;63:1111-1117.
    • (2015) J Hepatol , vol.63 , pp. 1111-1117
    • Yang, Y.H.1    Chen, W.C.2    Tsan, Y.T.3    Chen, M.J.4    Shih, W.T.5    Tsai, Y.H.6
  • 15
    • 84862269178 scopus 로고    scopus 로고
    • Long-term survival and predictors for mortality among dialysis patients in an endemic area for chronic liver disease: a national cohort study in Taiwan
    • Chien CC, Wang JJ, Sun YM, Sun DP, Sheu MJ, Weng SF, et al. Long-term survival and predictors for mortality among dialysis patients in an endemic area for chronic liver disease: a national cohort study in Taiwan. BMC Nephrol 2012;13:43.
    • (2012) BMC Nephrol , vol.13 , pp. 43
    • Chien, C.C.1    Wang, J.J.2    Sun, Y.M.3    Sun, D.P.4    Sheu, M.J.5    Weng, S.F.6
  • 16
    • 84880959431 scopus 로고    scopus 로고
    • Increased incidence of orthopedic fractures in cirrhotic patients: a nationwide population-based study
    • Tsai CF, Liu CJ, Chen TJ, Chu CJ, Lin HC, Lee FY, et al. Increased incidence of orthopedic fractures in cirrhotic patients: a nationwide population-based study. J Hepatol 2013;58:706-714.
    • (2013) J Hepatol , vol.58 , pp. 706-714
    • Tsai, C.F.1    Liu, C.J.2    Chen, T.J.3    Chu, C.J.4    Lin, H.C.5    Lee, F.Y.6
  • 17
    • 77957338399 scopus 로고    scopus 로고
    • Histamine2-receptor antagonists are an alternative to proton pump inhibitor in patients receiving clopidogrel
    • Wu CY, Chan FK, Wu MS, Kuo KN, Wang CB, Tsao CR, et al. Histamine2-receptor antagonists are an alternative to proton pump inhibitor in patients receiving clopidogrel. Gastroenterology 2010;139:1165-1171.
    • (2010) Gastroenterology , vol.139 , pp. 1165-1171
    • Wu, C.Y.1    Chan, F.K.2    Wu, M.S.3    Kuo, K.N.4    Wang, C.B.5    Tsao, C.R.6
  • 18
    • 79951968347 scopus 로고    scopus 로고
    • Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan
    • Cheng CL, Kao YH, Lin SJ, Lee CH, Lai ML. Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan. Pharmacoepidemiol Drug Saf 2011;20:236-242.
    • (2011) Pharmacoepidemiol Drug Saf , vol.20 , pp. 236-242
    • Cheng, C.L.1    Kao, Y.H.2    Lin, S.J.3    Lee, C.H.4    Lai, M.L.5
  • 20
    • 84900807809 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology
    • Linden KG, Leachman SA, Zager JS, Jakowatz JG, Viner JL, McLaren CE, et al. A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology. Cancer Prev Res (Phila) 2014;7:496-504.
    • (2014) Cancer Prev Res (Phila) , vol.7 , pp. 496-504
    • Linden, K.G.1    Leachman, S.A.2    Zager, J.S.3    Jakowatz, J.G.4    Viner, J.L.5    McLaren, C.E.6
  • 21
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: development and validation
    • Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-383.
    • (1987) J Chronic Dis , vol.40 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.L.3    MacKenzie, C.R.4
  • 22
    • 84961170459 scopus 로고    scopus 로고
    • Addition of simvastatin to standard therapy for the prevention of variceal rebleeding does not reduce rebleeding but increases survival in patients with cirrhosis
    • Abraldes JG, Villanueva C, Aracil C, Turnes J, Hernandez-Guerra M, Genesca J, et al. Addition of simvastatin to standard therapy for the prevention of variceal rebleeding does not reduce rebleeding but increases survival in patients with cirrhosis. Gastroenterology 2016;150:1160-1170.
    • (2016) Gastroenterology , vol.150 , pp. 1160-1170
    • Abraldes, J.G.1    Villanueva, C.2    Aracil, C.3    Turnes, J.4    Hernandez-Guerra, M.5    Genesca, J.6
  • 23
    • 0038216602 scopus 로고    scopus 로고
    • Alcohol relapse after liver transplantation for alcoholic liver disease: does it matter?
    • Pageaux GP, Bismuth M, Perney P, Costes V, Jaber S, Possoz P, et al. Alcohol relapse after liver transplantation for alcoholic liver disease: does it matter? J Hepatol 2003;38:629-634.
    • (2003) J Hepatol , vol.38 , pp. 629-634
    • Pageaux, G.P.1    Bismuth, M.2    Perney, P.3    Costes, V.4    Jaber, S.5    Possoz, P.6
  • 24
    • 84939165662 scopus 로고    scopus 로고
    • Recurrent alcoholic cirrhosis in severe alcoholic relapse after liver transplantation: a frequent and serious complication
    • Dumortier J, Dharancy S, Cannesson A, Lassailly G, Rolland B, Pruvot F-R, et al. Recurrent alcoholic cirrhosis in severe alcoholic relapse after liver transplantation: a frequent and serious complication. Am J Gastroenterol 2015;110:1160-1166.
    • (2015) Am J Gastroenterol , vol.110 , pp. 1160-1166
    • Dumortier, J.1    Dharancy, S.2    Cannesson, A.3    Lassailly, G.4    Rolland, B.5    Pruvot, F.-R.6
  • 25
    • 78649676642 scopus 로고    scopus 로고
    • A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization
    • Azar MM, Springer SA, Meyer JP, Altice FL. A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug Alcohol Depend 2010;112:178-193.
    • (2010) Drug Alcohol Depend , vol.112 , pp. 178-193
    • Azar, M.M.1    Springer, S.A.2    Meyer, J.P.3    Altice, F.L.4
  • 26
    • 20144379879 scopus 로고    scopus 로고
    • Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins
    • Arnaud C, Burger F, Steffens S, Veillard NR, Nguyen TH, Trono D, et al. Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins. Arterioscler Thromb Vasc Biol 2005;25:1231-1236.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1231-1236
    • Arnaud, C.1    Burger, F.2    Steffens, S.3    Veillard, N.R.4    Nguyen, T.H.5    Trono, D.6
  • 27
    • 84918578495 scopus 로고    scopus 로고
    • Statin use is associated with a reduced risk of fibrosis progression in chronic hepatitis C
    • Simon TG, King LY, Zheng H, Chung RT. Statin use is associated with a reduced risk of fibrosis progression in chronic hepatitis C. J Hepatol 2015;62:18-23.
    • (2015) J Hepatol , vol.62 , pp. 18-23
    • Simon, T.G.1    King, L.Y.2    Zheng, H.3    Chung, R.T.4
  • 28
    • 41149135364 scopus 로고    scopus 로고
    • Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2
    • Tuomisto TT, Lumivuori H, Kansanen E, Hakkinen SK, Turunen MP, van Thienen JV, et al. Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2. Cardiovasc Res 2008;78:175-184.
    • (2008) Cardiovasc Res , vol.78 , pp. 175-184
    • Tuomisto, T.T.1    Lumivuori, H.2    Kansanen, E.3    Hakkinen, S.K.4    Turunen, M.P.5    van Thienen, J.V.6
  • 29
    • 2542500709 scopus 로고    scopus 로고
    • KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation
    • SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, et al. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation. J Exp Med 2004;199:1305-1315.
    • (2004) J Exp Med , vol.199 , pp. 1305-1315
    • SenBanerjee, S.1    Lin, Z.2    Atkins, G.B.3    Greif, D.M.4    Rao, R.M.5    Kumar, A.6
  • 30
    • 84871211218 scopus 로고    scopus 로고
    • The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial–stellate cell deactivation induced by statins
    • Marrone G, Russo L, Rosado E, Hide D, García-Cardeña G, García-Pagán JC, et al. The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial–stellate cell deactivation induced by statins. J Hepatol 2013;58:98-103.
    • (2013) J Hepatol , vol.58 , pp. 98-103
    • Marrone, G.1    Russo, L.2    Rosado, E.3    Hide, D.4    García-Cardeña, G.5    García-Pagán, J.C.6
  • 31
    • 84941281919 scopus 로고    scopus 로고
    • KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins
    • Marrone G, Maeso-Díaz R, García-Cardena G, Abraldes JG, García-Pagán JC, Bosch J, et al. KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins. Gut 2015;64:1434-1443.
    • (2015) Gut , vol.64 , pp. 1434-1443
    • Marrone, G.1    Maeso-Díaz, R.2    García-Cardena, G.3    Abraldes, J.G.4    García-Pagán, J.C.5    Bosch, J.6
  • 32
    • 67651150050 scopus 로고    scopus 로고
    • Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development
    • Delang L, Paeshuyse J, Vliegen I, Leyssen P, Obeid S, Durantel D, et al. Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development. Hepatology 2009;50:6-16.
    • (2009) Hepatology , vol.50 , pp. 6-16
    • Delang, L.1    Paeshuyse, J.2    Vliegen, I.3    Leyssen, P.4    Obeid, S.5    Durantel, D.6
  • 34
    • 33745903898 scopus 로고    scopus 로고
    • Different anti-HCV profiles of statins and their potential for combination therapy with interferon
    • Ikeda M, Abe K, Yamada M, Dansako H, Naka K, Kato N. Different anti-HCV profiles of statins and their potential for combination therapy with interferon. Hepatology 2006;44:117-125.
    • (2006) Hepatology , vol.44 , pp. 117-125
    • Ikeda, M.1    Abe, K.2    Yamada, M.3    Dansako, H.4    Naka, K.5    Kato, N.6
  • 35
    • 78650457786 scopus 로고    scopus 로고
    • Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C
    • Rao GA, Pandya PK. Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C. Gastroenterology 2011;140:144-152.
    • (2011) Gastroenterology , vol.140 , pp. 144-152
    • Rao, G.A.1    Pandya, P.K.2
  • 36
    • 0036158675 scopus 로고    scopus 로고
    • 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis
    • Kusama T, Mukai M, Iwasaki T, Tatsuta M, Matsumoto Y, Akedo H, et al. 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. Gastroenterology 2002;122:308-317.
    • (2002) Gastroenterology , vol.122 , pp. 308-317
    • Kusama, T.1    Mukai, M.2    Iwasaki, T.3    Tatsuta, M.4    Matsumoto, Y.5    Akedo, H.6
  • 38
    • 65349094504 scopus 로고    scopus 로고
    • Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial
    • Abraldes JG, Albillos A, Banares R, Turnes J, Gonzalez R, Garcia-Pagan JC, et al. Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial. Gastroenterology 2009;136:1651-1658.
    • (2009) Gastroenterology , vol.136 , pp. 1651-1658
    • Abraldes, J.G.1    Albillos, A.2    Banares, R.3    Turnes, J.4    Gonzalez, R.5    Garcia-Pagan, J.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.