Interleukin-1 blockade in heart failure with preserved ejection fraction: rationale and design of the Diastolic Heart Failure Anakinra Response Trial 2 (D-HART2)

Clinical Cardiology

Volumn 40, Issue 9, 2017, Pages 626-632

  Van Tassell, Benjamin W ^a   Buckley, Leo F ^a   Carbone, Salvatore ^a,b   Trankle, Cory R ^a   Canada, Justin M ^a   Dixon, Dave L ^a   Abouzaki, Nayef ^a   Oddi Erdle, Claudia ^a   Biondi Zoccai, Giuseppe ^c   Arena, Ross ^d   Abbate, Antonio ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

clinical trial study design; Heart Failure; Interleukin 1

Indexed keywords

ANAKINRA; INTERLEUKIN 1; PLACEBO; ANTIINFLAMMATORY AGENT; CARDIOVASCULAR AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ARTICLE; BODY COMPOSITION; CARDIORESPIRATORY FITNESS; CLINICAL ARTICLE; CLINICAL OUTCOME; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENDOTHELIAL FUNCTION; ENDOTHELIUM; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HEART FUNCTION; HUMAN; LUNG VENTILATION; NUTRITIONAL STATUS; OXYGEN CONSUMPTION; PHASE 2 CLINICAL TRIAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT DURATION; ANTAGONISTS AND INHIBITORS; CLINICAL PROTOCOL; CLINICAL TRIAL; CONVALESCENCE; CROSSOVER PROCEDURE; EXERCISE TOLERANCE; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HEART VENTRICLE; IMMUNOLOGY; METHODOLOGY; PATHOPHYSIOLOGY; PILOT STUDY; TIME FACTOR; TREATMENT OUTCOME; VIRGINIA;

ANTI-INFLAMMATORY AGENTS; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR AGENTS; CLINICAL PROTOCOLS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EXERCISE TOLERANCE; HEART FAILURE; HEART VENTRICLES; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; PILOT PROJECTS; RECOVERY OF FUNCTION; RESEARCH DESIGN; STROKE VOLUME; TIME FACTORS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT; VIRGINIA;

EID: 85018427537     PISSN: 01609289     EISSN: 19328737     Source Type: Journal    
DOI: 10.1002/clc.22719     Document Type: Article

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