Effects of vasodilation in heart failure with preserved or reduced ejection fraction: Implications of distinct pathophysiologies on response to therapy

Journal of the American College of Cardiology

Volumn 59, Issue 5, 2012, Pages 442-451

  Schwartzenberg, Shmuel ^a   Redfield, Margaret M ^a   From, Aaron M ^a   Sorajja, Paul ^a   Nishimura, Rick A ^a   Borlaug, Barry A ^a  

^a MAYO CLINIC ROCHESTER   (United States)

Author keywords

heart failure; treatment; vasodilation; ventricular function; ventricular arterial interaction

Indexed keywords

NITROPRUSSIDE SODIUM; VASODILATOR AGENT;

ADULT; AGED; ARTERIAL PRESSURE; ARTICLE; BLOOD OXYGEN TENSION; CONTROLLED STUDY; DOPPLER ECHOCARDIOGRAPHY; DRUG DOSE INCREASE; DRUG DOSE TITRATION; FEMALE; HEART AFTERLOAD; HEART CATHETERIZATION; HEART EJECTION FRACTION; HEART FAILURE; HEART HEMODYNAMICS; HEART OUTPUT; HEART STROKE VOLUME; HEART VOLUME; HUMAN; LUNG VASCULAR RESISTANCE; LUNG WEDGE PRESSURE; MAJOR CLINICAL STUDY; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PULSE PRESSURE; THERMODILUTION; VASODILATATION;

AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HEART CATHETERIZATION; HEART FAILURE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; NITROPRUSSIDE; PROGNOSIS; PULMONARY WEDGE PRESSURE; RETROSPECTIVE STUDIES; STROKE VOLUME; VASODILATION; VASODILATOR AGENTS; VENTRICULAR FUNCTION, RIGHT;

EID: 84856140884     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.09.062     Document Type: Article

References (29)

1. B.A. Borlaug, W.J. Paulus Heart failure with preserved ejection fraction: pathophysiology, diagnosis and treatment Eur Heart J 32 2011 670 679
2. G.W. De Keulenaer, D.L. Brutsaert Systolic and diastolic heart failure are overlapping phenotypes within the heart failure spectrum Circulation 123 2011 1996 2005
3. S. Yusuf, M.A. Pfeffer, K. Swedberg Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial Lancet 362 2003 777 781 (Pubitemid 37093918)
4. J.G. Cleland, M. Tendera, J. Adamus, N. Freemantle, L. Polonski, J. Taylor The Perindopril in Elderly People With Chronic Heart Failure (PEP-CHF) study Eur Heart J 27 2006 2338 2345 (Pubitemid 44453578)
5. B.M. Massie, P.E. Carson, J.J. McMurray Irbesartan in patients with heart failure and preserved ejection fraction N Engl J Med 359 2008 2456 2467
6. J.N. Cohn, J.A. Franciosa Vasodilator therapy of cardiac failure (first of two parts) N Engl J Med 297 1977 27 31 (Pubitemid 8114597)
7. J.D. Carroll, R.M. Lang, A.L. Neumann, K.M. Borow, S.I. Rajfer The differential effects of positive inotropic and vasodilator therapy on diastolic properties in patients with congestive cardiomyopathy Circulation 74 1986 815 825 (Pubitemid 16007198)
8. D.A. Kass, W.L. Maughan From "Emax" to pressure-volume relations: a broader view Circulation 77 1988 1203 1212
9. D.A. Kass, R.P. Kelly Ventriculo-arterial coupling: concepts, assumptions, and applications Ann Biomed Engineer 20 1992 41 62
10. M. Kawaguchi, I. Hay, B. Fetics, D.A. Kass Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic reserve limitations Circulation 107 2003 714 720 (Pubitemid 36222599)
11. B.A. Borlaug, C.S. Lam, V.L. Roger, R.J. Rodeheffer, M.M. Redfield Contractility and ventricular systolic stiffening in hypertensive heart disease insights into the pathogenesis of heart failure with preserved ejection fraction J Am Coll Cardiol 54 2009 410 418
12. B.A. Borlaug, D.A. Kass Ventricular-vascular interaction in heart failure Heart Fail Clin 4 2008 23 36 (Pubitemid 351289326)
13. B.A. Borlaug, R.A. Nishimura, P. Sorajja, C.S. Lam, M.M. Redfield Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction Circ Heart Fail 3 2010 588 595
14. B.A. Borlaug, V. Melenovsky, M.M. Redfield Impact of arterial load and loading sequence on left ventricular tissue velocities in humans J Am Coll Cardiol 50 2007 1570 1577 (Pubitemid 47532334)
15. L. van Heerebeek, A. Borbely, H.W. Niessen Myocardial structure and function differ in systolic and diastolic heart failure Circulation 113 2006 1966 1973
16. W.C. Little, C.P. Cheng Left ventricular-arterial coupling in conscious dogs Am J Physiol 261 1991 H70 H76
17. H. Asanoi, S. Sasayama, T. Kameyama Ventriculoarterial coupling in normal and failing heart in humans Circ Res 65 1989 483 493 (Pubitemid 19194635)
18. S.K. Gandhi, J.C. Powers, A.M. Nomeir The pathogenesis of acute pulmonary edema associated with hypertension N Engl J Med 344 2001 17 22 (Pubitemid 32064840)
19. C.H. Chen, M. Nakayama, E. Nevo, B.J. Fetics, W.L. Maughan, D.A. Kass Coupled systolic-ventricular and vascular stiffening with age: implications for pressure regulation and cardiac reserve in the elderly J Am Coll Cardiol 32 1998 1221 1227
20. N.K. Sweitzer, M. Lopatin, C.W. Yancy, R.M. Mills, L.W. Stevenson Comparison of clinical features and outcomes of patients hospitalized with heart failure and normal ejection fraction (> or =55%) versus those with mildly reduced (40% to 55%) and moderately to severely reduced (<40%) fractions Am J Cardiol 101 2008 1151 1156
21. T.C. Gillebert, A.F. Leite-Moreira, S.G. De Hert Load dependent diastolic dysfunction in heart failure Heart Fail Rev 5 2000 345 355 (Pubitemid 32000432)
22. S.D. Solomon, R. Janardhanan, A. Verma Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trial Lancet 369 2007 2079 2087 (Pubitemid 46935945)
23. W.J. Paulus, P.J. Vantrimpont, A.M. Shah Acute effects of nitric oxide on left ventricular relaxation and diastolic distensibility in humans Assessment by bicoronary sodium nitroprusside infusion Circulation 89 1994 2070 2078 (Pubitemid 24142783)
24. C. Risoe, S. Simonsen, K. Rootwelt, S. Sire, O.A. Smiseth Nitroprusside and regional vascular capacitance in patients with severe congestive heart failure Circulation 85 1992 997 1002
25. O.A. Smiseth, D.E. Manyari, J.A. Lima Modulation of vascular capacitance by angiotensin and nitroprusside: a mechanism of changes in pericardial pressure Circulation 76 1987 875 883 (Pubitemid 17151346)
26. F.L. Abel, J.A. Waldhausen Effects of alterations in pulmonary vascular resistance on right ventricular function J Thorac Cardiovasc Surg 54 1967 886 894
27. S. Ghio Pulmonary hypertension in advanced heart failure Herz 30 2005 311 317 (Pubitemid 40922285)
28. C.S. Lam, V.L. Roger, R.J. Rodeheffer, B.A. Borlaug, F.T. Enders, M.M. Redfield Pulmonary hypertension in heart failure with preserved ejection fraction: a community-based study J Am Coll Cardiol 53 2009 1119 1126
29. G.L. Freeman, W.C. Little, R.A. O'Rourke The effect of vasoactive agents on the left ventricular end-systolic pressure-volume relation in closed-chest dogs Circulation 74 1986 1107 1113 (Pubitemid 17174960)