PA-X protein contributes to virulence of triple-reassortant H1N2 influenza virus by suppressing early immune responses in swine

Virology

Volumn 508, Issue , 2017, Pages 45-53

  Xu, Guanlong ^a,b   Zhang, Xuxiao ^a   Liu, Qinfang ^c   Bing, Guoxia ^d   Hu, Zhe ^a   Sun, Honglei ^a   Xiong, Xin ^a   Jiang, Ming ^a   He, Qiming ^a   Wang, Yu ^a   Pu, Juan ^a   Guo, Xin ^a   Yang, Hanchun ^a   Liu, Jinhua ^a   Sun, Yipeng ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b Institute of Veterinary Medicine Control   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d Department of Veterinary Public Health China Animal Disease Control Center   (China)

Author keywords

Immune responses; PA X protein; Swine influenza virus; Virulence

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; HYBRID PROTEIN; INTERLEUKIN 12; INTERLEUKIN 6; MESSENGER RNA; PA X PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; INTERFERON; PA-X PROTEIN, INFLUENZA A VIRUS; REPRESSOR PROTEIN; VIRAL PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA A; INFLUENZA A VIRUS (H1N2); INNATE IMMUNITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; VIRUS VIRULENCE; ANIMAL; GENETIC REASSORTMENT; GENETICS; IMMUNOLOGY; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PHYSIOLOGY; PIG; SWINE DISEASE; VETERINARY; VIROLOGY; VIRULENCE;

ANIMALS; INFLUENZA A VIRUS, H1N2 SUBTYPE; INTERFERONS; ORTHOMYXOVIRIDAE INFECTIONS; REASSORTANT VIRUSES; REPRESSOR PROTEINS; SWINE; SWINE DISEASES; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 85018389579     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2017.05.002     Document Type: Article

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