메뉴 건너뛰기




Volumn 91, Issue 10, 2017, Pages

Pathology in permissive syrian hamsters after infection with species C human adenovirus (HAdV-C) is the result of virus replication: HAdV-C6 replicates more and causes more pathology than HAdV-C5

Author keywords

Adenoviruses; Hamster; Viral pathogenesis

Indexed keywords

ALANINE AMINOTRANSFERASE; CLODRONIC ACID; CYCLOPHOSPHAMIDE; LIPOSOME;

EID: 85018281045     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00284-17     Document Type: Article
Times cited : (27)

References (59)
  • 1
    • 84974682766 scopus 로고    scopus 로고
    • Adenoviridae
    • Knipe DM, Howley PM (ed), Lippincott Williams & Wilkins, Philadelphia, PA
    • Berk AJ. 2013. Adenoviridae, p 1704-1731. In Knipe DM, Howley PM (ed), Fields virology, 6th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
    • (2013) Fields virology, 6th ed , pp. 1704-1731
    • Berk, A.J.1
  • 2
    • 84974708379 scopus 로고    scopus 로고
    • Adenoviruses
    • Knipe DM, Howley PM (ed), Lippincott Williams & Wilkins, Philadelphia, PA
    • Wold WSM, Ison MG. 2013. Adenoviruses, p 1732. In Knipe DM, Howley PM (ed), Fields virology, 6th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
    • (2013) Fields virology, 6th ed , pp. 1732
    • Wold, W.S.M.1    Ison, M.G.2
  • 6
    • 32944474223 scopus 로고    scopus 로고
    • Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors
    • Thomas MA, Spencer JF, La Regina MC, Dhar D, Tollefson AE, Toth K, Wold WS. 2006. Syrian hamster as a permissive immunocompetent animal model for the study of oncolytic adenovirus vectors. Cancer Res 66:1270-1276. https://doi.org/10.1158/0008-5472.CAN-05-3497.
    • (2006) Cancer Res , vol.66 , pp. 1270-1276
    • Thomas, M.A.1    Spencer, J.F.2    La Regina, M.C.3    Dhar, D.4    Tollefson, A.E.5    Toth, K.6    Wold, W.S.7
  • 7
    • 0021281914 scopus 로고
    • A new animal model for human respiratory tract disease due to adenovirus
    • Pacini DL, Dubovi EJ, Clyde WA, Jr. 1984. A new animal model for human respiratory tract disease due to adenovirus. J Infect Dis 150:92-97. https://doi.org/10.1093/infdis/150.1.92.
    • (1984) J Infect Dis , vol.150 , pp. 92-97
    • Pacini, D.L.1    Dubovi, E.J.2    Clyde, W.A.3
  • 9
    • 54749109597 scopus 로고    scopus 로고
    • Immunosuppression enhances oncolytic adenovirus replication and anti tumor efficacy in the Syrian hamster model
    • Thomas MA, Spencer JF, Toth K, Sagartz JE, Phillips N, Wold WSM. 2008. Immunosuppression enhances oncolytic adenovirus replication and anti tumor efficacy in the Syrian hamster model. Mol Ther 16:1665-1673. https://doi.org/10.1038/mt.2008.162.
    • (2008) Mol Ther , vol.16 , pp. 1665-1673
    • Thomas, M.A.1    Spencer, J.F.2    Toth, K.3    Sagartz, J.E.4    Phillips, N.5    Wold, W.S.M.6
  • 11
    • 33847210729 scopus 로고    scopus 로고
    • Targeting interferon-γ increases antitumor efficacy and reduces hepatotoxicity of E1A-mutated spread-enhanced oncolytic adenovirus
    • Shashkova EV, Spencer JF, Wold WSM, Doronin K. 2007. Targeting interferon-γ increases antitumor efficacy and reduces hepatotoxicity of E1A-mutated spread-enhanced oncolytic adenovirus. Mol Ther 15: 598-607. https://doi.org/10.1038/sj.mt.6300064.
    • (2007) Mol Ther , vol.15 , pp. 598-607
    • Shashkova, E.V.1    Spencer, J.F.2    Wold, W.S.M.3    Doronin, K.4
  • 12
    • 70449657531 scopus 로고    scopus 로고
    • New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster
    • Spencer JF, Sagartz JE, Wold WSM, Toth K. 2009. New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster. Cancer Gene Ther 16:912-922. https://doi.org/10.1038/ cgt.2009.36.
    • (2009) Cancer Gene Ther , vol.16 , pp. 912-922
    • Spencer, J.F.1    Sagartz, J.E.2    Wold, W.S.M.3    Toth, K.4
  • 13
    • 70349873326 scopus 로고    scopus 로고
    • Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model
    • Dhar D, Spencer JF, Toth K, Wold WSM. 2009. Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model. Mol Ther 17: 1724-1732. https://doi.org/10.1038/mt.2009.156.
    • (2009) Mol Ther , vol.17 , pp. 1724-1732
    • Dhar, D.1    Spencer, J.F.2    Toth, K.3    Wold, W.S.M.4
  • 14
    • 84884597134 scopus 로고    scopus 로고
    • The role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors
    • Young BA, Spencer JF, Ying B, Tollefson AE, Toth K, Wold WS. 2013. The role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors. Cancer Gene Ther 20:521-530. https://doi.org/10.1038/cgt.2013.49.
    • (2013) Cancer Gene Ther , vol.20 , pp. 521-530
    • Young, B.A.1    Spencer, J.F.2    Ying, B.3    Tollefson, A.E.4    Toth, K.5    Wold, W.S.6
  • 15
    • 84884592718 scopus 로고    scopus 로고
    • The effects of radiation on antitumor efficacy of an oncolytic adenovirus vector in the Syrian hamster model
    • Young BA, Spencer JF, Ying B, Toth K, Wold WS. 2013. The effects of radiation on antitumor efficacy of an oncolytic adenovirus vector in the Syrian hamster model. Cancer Gene Ther 20:531-537. https://doi.org/10 .1038/cgt.2013.50.
    • (2013) Cancer Gene Ther , vol.20 , pp. 531-537
    • Young, B.A.1    Spencer, J.F.2    Ying, B.3    Toth, K.4    Wold, W.S.5
  • 16
    • 84897956577 scopus 로고    scopus 로고
    • Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters
    • Dhar D, Toth K, Wold WS. 2014. Cycles of transient high-dose cyclophosphamide administration and intratumoral oncolytic adenovirus vector injection for long-term tumor suppression in Syrian hamsters. Cancer Gene Ther 21:171-178. https://doi.org/10.1038/cgt.2014.13.
    • (2014) Cancer Gene Ther , vol.21 , pp. 171-178
    • Dhar, D.1    Toth, K.2    Wold, W.S.3
  • 18
    • 34548473135 scopus 로고    scopus 로고
    • Human adenovirus replicates in immunocompetent models of pancreatic cancer in Syrian hamsters
    • Bortolanza S, Alzuguren P, Bunuales M, Qian C, Prieto J, Hernandez-Alcoceba R. 2007. Human adenovirus replicates in immunocompetent models of pancreatic cancer in Syrian hamsters. Hum Gene Ther 18: 681-690. https://doi.org/10.1089/hum.2007.017.
    • (2007) Hum Gene Ther , vol.18 , pp. 681-690
    • Bortolanza, S.1    Alzuguren, P.2    Bunuales, M.3    Qian, C.4    Prieto, J.5    Hernandez-Alcoceba, R.6
  • 19
    • 62549149856 scopus 로고    scopus 로고
    • Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats
    • Sonabend AM, Ulasov IV, Han Y, Rolle CE, Nandi S, Cao D, Tyler MA, Lesniak MS. 2009. Biodistribution of an oncolytic adenovirus after intracranial injection in permissive animals: a comparative study of Syrian hamsters and cotton rats. Cancer Gene Ther 16:362-372. https://doi.org/ 10.1038/cgt.2008.80.
    • (2009) Cancer Gene Ther , vol.16 , pp. 362-372
    • Sonabend, A.M.1    Ulasov, I.V.2    Han, Y.3    Rolle, C.E.4    Nandi, S.5    Cao, D.6    Tyler, M.A.7    Lesniak, M.S.8
  • 24
    • 68949218981 scopus 로고    scopus 로고
    • Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters
    • Bortolanza S, Bunuales M, Alzuguren P, Lamas O, Aldabe R, Prieto J, Hernandez-Alcoceba R. 2009. Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters. Cancer Gene Ther 16:703-712. https://doi.org/ 10.1038/cgt.2009.12.
    • (2009) Cancer Gene Ther , vol.16 , pp. 703-712
    • Bortolanza, S.1    Bunuales, M.2    Alzuguren, P.3    Lamas, O.4    Aldabe, R.5    Prieto, J.6    Hernandez-Alcoceba, R.7
  • 25
    • 84879965657 scopus 로고    scopus 로고
    • Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters
    • Hasegawa N, Abei M, Yokoyama KK, Fukuda K, Seo E, Kawashima R, Nakano Y, Yamada T, Nakade K, Hamada H, Obata Y, Hyodo I. 2013. Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters. Int J Cancer 133:1479-1488. https://doi.org/10 .1002/ijc.28132.
    • (2013) Int J Cancer , vol.133 , pp. 1479-1488
    • Hasegawa, N.1    Abei, M.2    Yokoyama, K.K.3    Fukuda, K.4    Seo, E.5    Kawashima, R.6    Nakano, Y.7    Yamada, T.8    Nakade, K.9    Hamada, H.10    Obata, Y.11    Hyodo, I.12
  • 27
    • 84929043772 scopus 로고    scopus 로고
    • Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer
    • LaRocca CJ, Han J, Gavrikova T, Armstrong L, Oliveira AR, Shanley R, Vickers SM, Yamamoto M, Davydova J. 2015. Oncolytic adenovirus expressing interferon alpha in a syngeneic Syrian hamster model for the treatment of pancreatic cancer. Surgery 157:888-898. https://doi.org/ 10.1016/j.surg.2015.01.006.
    • (2015) Surgery , vol.157 , pp. 888-898
    • LaRocca, C.J.1    Han, J.2    Gavrikova, T.3    Armstrong, L.4    Oliveira, A.R.5    Shanley, R.6    Vickers, S.M.7    Yamamoto, M.8    Davydova, J.9
  • 28
    • 84969277547 scopus 로고    scopus 로고
    • Evaluation of polymer shielding for adenovirus serotype 6 (Ad6) for systemic virotherapy against human prostate cancers
    • Nguyen TV, Heller GJ, Barry ME, Crosby CM, Turner MA, Barry MA. 2016. Evaluation of polymer shielding for adenovirus serotype 6 (Ad6) for systemic virotherapy against human prostate cancers. Mol Ther Oncolytics 3:15021. https://doi.org/10.1038/mto.2015.21.
    • (2016) Mol Ther Oncolytics , vol.3 , pp. 15021
    • Nguyen, T.V.1    Heller, G.J.2    Barry, M.E.3    Crosby, C.M.4    Turner, M.A.5    Barry, M.A.6
  • 29
    • 84866780520 scopus 로고    scopus 로고
    • Syrian hamster as an animal model to study oncolytic adenoviruses and to evaluate the efficacy of antiviral compounds
    • Wold WS, Toth K. 2012. Syrian hamster as an animal model to study oncolytic adenoviruses and to evaluate the efficacy of antiviral compounds. Adv Cancer Res 115:69-92. https://doi.org/10.1016/B978-0-12-398342-8.00003-3.
    • (2012) Adv Cancer Res , vol.115 , pp. 69-92
    • Wold, W.S.1    Toth, K.2
  • 30
    • 80555127437 scopus 로고    scopus 로고
    • Syrian hamster tumor model to study oncolytic Ad5-based vectors
    • Dhar D, Toth K, Wold WS. 2012. Syrian hamster tumor model to study oncolytic Ad5-based vectors. Methods Mol Biol 797:53-63. https://doi .org/10.1007/978-1-61779-340-0_4.
    • (2012) Methods Mol Biol , vol.797 , pp. 53-63
    • Dhar, D.1    Toth, K.2    Wold, W.S.3
  • 31
    • 84940732691 scopus 로고    scopus 로고
    • STAT2 knockout Syrian hamsters support enhanced replication and pathogenicity of human adenovirus, revealing an important role of type I interferon response in viral control
    • Toth K, Lee SR, Ying B, Spencer JF, Tollefson AE, Sagartz JE, Kong IK, Wang Z, Wold WS. 2015. STAT2 knockout Syrian hamsters support enhanced replication and pathogenicity of human adenovirus, revealing an important role of type I interferon response in viral control. PLoS Pathog 11:e1005084. https://doi.org/10.1371/journal.ppat.1005084.
    • (2015) PLoS Pathog , vol.11
    • Toth, K.1    Lee, S.R.2    Ying, B.3    Spencer, J.F.4    Tollefson, A.E.5    Sagartz, J.E.6    Kong, I.K.7    Wang, Z.8    Wold, W.S.9
  • 32
    • 44449121495 scopus 로고    scopus 로고
    • Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirusinduced mortality in a permissive, immunosuppressed animal model
    • Toth K, Spencer JF, Dhar D, Sagartz JE, Buller RM, Painter GR, Wold WSM. 2008. Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirusinduced mortality in a permissive, immunosuppressed animal model. Proc Natl Acad Sci U S A 105:7293-7297. https://doi.org/10.1073/pnas .0800200105.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 7293-7297
    • Toth, K.1    Spencer, J.F.2    Dhar, D.3    Sagartz, J.E.4    Buller, R.M.5    Painter, G.R.6    Wold, W.S.M.7
  • 33
    • 84908441171 scopus 로고    scopus 로고
    • Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model
    • Tollefson AE, Spencer JF, Ying B, Buller RM, Wold WS, Toth K. 2014. Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model. Antiviral Res 112:38-46. https://doi.org/10.1016/j.antiviral.2014.10.005.
    • (2014) Antiviral Res , vol.112 , pp. 38-46
    • Tollefson, A.E.1    Spencer, J.F.2    Ying, B.3    Buller, R.M.4    Wold, W.S.5    Toth, K.6
  • 35
    • 84925845408 scopus 로고    scopus 로고
    • Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters
    • Toth K, Ying B, Tollefson AE, Spencer JF, Balakrishnan L, Sagartz JE, Buller RM, Wold WS. 2015. Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters. Viruses 7:1409-1428. https://doi.org/10 .3390/v7031409.
    • (2015) Viruses , vol.7 , pp. 1409-1428
    • Toth, K.1    Ying, B.2    Tollefson, A.E.3    Spencer, J.F.4    Balakrishnan, L.5    Sagartz, J.E.6    Buller, R.M.7    Wold, W.S.8
  • 36
    • 84940106869 scopus 로고    scopus 로고
    • Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters
    • Ying B, Toth K, Spencer JF, Aurora R, Wold WSM. 2015. Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters. Virology 485:305-312. https://doi.org/10.1016/j.virol.2015.07.024.
    • (2015) Virology , vol.485 , pp. 305-312
    • Ying, B.1    Toth, K.2    Spencer, J.F.3    Aurora, R.4    Wold, W.S.M.5
  • 39
    • 80052966552 scopus 로고    scopus 로고
    • Mining the adenovirus virome for oncolytics against multiple solid tumor types
    • Chen CY, Weaver EA, Khare R, May SM, Barry MA. 2011. Mining the adenovirus virome for oncolytics against multiple solid tumor types. Cancer Gene Ther 18:744-750. https://doi.org/10.1038/cgt.2011.47.
    • (2011) Cancer Gene Ther , vol.18 , pp. 744-750
    • Chen, C.Y.1    Weaver, E.A.2    Khare, R.3    May, S.M.4    Barry, M.A.5
  • 40
    • 84919429847 scopus 로고    scopus 로고
    • Amplified and persistent immune responses generated by single-cycle replicating adenovirus vaccines
    • Crosby CM, Nehete P, Sastry KJ, Barry MA. 2015. Amplified and persistent immune responses generated by single-cycle replicating adenovirus vaccines. J Virol 89:669-675. https://doi.org/10.1128/JVI.02184-14.
    • (2015) J Virol , vol.89 , pp. 669-675
    • Crosby, C.M.1    Nehete, P.2    Sastry, K.J.3    Barry, M.A.4
  • 41
    • 70449130491 scopus 로고    scopus 로고
    • Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agents
    • Shashkova EV, May SM, Barry MA. 2009. Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agents. Virology 394:311-320. https://doi.org/10.1016/j.virol.2009.08.038.
    • (2009) Virology , vol.394 , pp. 311-320
    • Shashkova, E.V.1    May, S.M.2    Barry, M.A.3
  • 43
    • 0031060294 scopus 로고    scopus 로고
    • Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ
    • Wolff G, Worgall S, vanRooijen N, Song WR, Harvey BG, Crystal RG. 1997. Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ. J Virol 71:624-629.
    • (1997) J Virol , vol.71 , pp. 624-629
    • Wolff, G.1    Worgall, S.2    vanRooijen, N.3    Song, W.R.4    Harvey, B.G.5    Crystal, R.G.6
  • 44
    • 0033926002 scopus 로고    scopus 로고
    • Replicative adenoviruses for cancer therapy
    • Alemany R, Balague C, Curiel DT. 2000. Replicative adenoviruses for cancer therapy. Nat Biotechnol 18:723-727. https://doi.org/10.1038/ 77283.
    • (2000) Nat Biotechnol , vol.18 , pp. 723-727
    • Alemany, R.1    Balague, C.2    Curiel, D.T.3
  • 45
    • 0031034030 scopus 로고    scopus 로고
    • Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
    • Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. 1997. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum Gene Ther 8:37-77. https://doi.org/10.1089/ hum.1997.8.1-37.
    • (1997) Hum Gene Ther , vol.8 , pp. 37-77
    • Worgall, S.1    Wolff, G.2    Falck-Pedersen, E.3    Crystal, R.G.4
  • 46
    • 85027921140 scopus 로고    scopus 로고
    • Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer
    • Khare R, May SM, Vetrini F, Weaver EA, Palmer D, Rosewell A, Grove N, Ng P, Barry MA. 2011. Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer. Mol Ther 19:1254-1262. https://doi.org/10.1038/mt.2011.71.
    • (2011) Mol Ther , vol.19 , pp. 1254-1262
    • Khare, R.1    May, S.M.2    Vetrini, F.3    Weaver, E.A.4    Palmer, D.5    Rosewell, A.6    Grove, N.7    Ng, P.8    Barry, M.A.9
  • 47
    • 84875553236 scopus 로고    scopus 로고
    • Circulating antibodies and macrophages as modulators of adenovirus pharmacology
    • Khare R, Hillestad ML, Xu Z, Byrnes AP, Barry MA. 2013. Circulating antibodies and macrophages as modulators of adenovirus pharmacology. J Virol 87:3678-3686. https://doi.org/10.1128/JVI.01392-12.
    • (2013) J Virol , vol.87 , pp. 3678-3686
    • Khare, R.1    Hillestad, M.L.2    Xu, Z.3    Byrnes, A.P.4    Barry, M.A.5
  • 48
    • 79952536568 scopus 로고    scopus 로고
    • Characterization of species C human adenovirus serotype 6 (Ad6)
    • Weaver EA, Hillestad ML, Khare R, Palmer D, Ng P, Barry MA. 2011. Characterization of species C human adenovirus serotype 6 (Ad6). Virology 412:19-27. https://doi.org/10.1016/j.virol.2010.10.041.
    • (2011) Virology , vol.412 , pp. 19-27
    • Weaver, E.A.1    Hillestad, M.L.2    Khare, R.3    Palmer, D.4    Ng, P.5    Barry, M.A.6
  • 49
    • 84949845384 scopus 로고    scopus 로고
    • Comparison of the life cycles of genetically distant species C and species D human adenoviruses Ad6 and Ad26 in human cells
    • Turner MA, Middha S, Hofherr SE, Barry MA. 2015. Comparison of the life cycles of genetically distant species C and species D human adenoviruses Ad6 and Ad26 in human cells. J Virol 89:12401-12417. https://doi .org/10.1128/JVI.01534-15.
    • (2015) J Virol , vol.89 , pp. 12401-12417
    • Turner, M.A.1    Middha, S.2    Hofherr, S.E.3    Barry, M.A.4
  • 50
    • 0033756313 scopus 로고    scopus 로고
    • Blood clearance rates of adenovirus type 5 in mice
    • Alemany R, Suzuki K, Curiel DT. 2000. Blood clearance rates of adenovirus type 5 in mice. J Gen Virol 81:2605-2609. https://doi.org/10.1099/ 0022-1317-81-11-2605.
    • (2000) J Gen Virol , vol.81 , pp. 2605-2609
    • Alemany, R.1    Suzuki, K.2    Curiel, D.T.3
  • 51
    • 80053444500 scopus 로고    scopus 로고
    • Rapid and efficient clearance of blood-borne virus by liver sinusoidal endothelium
    • Ganesan LP, Mohanty S, Kim J, Clark KR, Robinson JM, Anderson CL. 2011. Rapid and efficient clearance of blood-borne virus by liver sinusoidal endothelium. PLoS Pathog 7:e1002281. https://doi.org/10.1371/ journal.ppat.1002281.
    • (2011) PLoS Pathog , vol.7
    • Ganesan, L.P.1    Mohanty, S.2    Kim, J.3    Clark, K.R.4    Robinson, J.M.5    Anderson, C.L.6
  • 52
    • 84910107014 scopus 로고    scopus 로고
    • SR-A and SREC-I binding peptides increase HDAd-mediated liver transduction
    • Piccolo P, Annunziata P, Mithbaokar P, Brunetti-Pierri N. 2014. SR-A and SREC-I binding peptides increase HDAd-mediated liver transduction. Gene Ther 21:950-957. https://doi.org/10.1038/gt.2014.71.
    • (2014) Gene Ther , vol.21 , pp. 950-957
    • Piccolo, P.1    Annunziata, P.2    Mithbaokar, P.3    Brunetti-Pierri, N.4
  • 53
    • 0034980914 scopus 로고    scopus 로고
    • Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver
    • Tao N, Gao GP, Parr M, Johnston J, Baradet T, Wilson JM, Barsoum J, Fawell SE. 2001. Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver. Mol Ther 3:28-35. https://doi.org/10.1006/mthe.2000.0227.
    • (2001) Mol Ther , vol.3 , pp. 28-35
    • Tao, N.1    Gao, G.P.2    Parr, M.3    Johnston, J.4    Baradet, T.5    Wilson, J.M.6    Barsoum, J.7    Fawell, S.E.8
  • 55
    • 0030756389 scopus 로고    scopus 로고
    • The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors
    • Lieber A, He CY, Meuse L, Schowalter D, Kirillova I, Winther B, Kay MA. 1997. The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors. J Virol 71:8798-8807.
    • (1997) J Virol , vol.71 , pp. 8798-8807
    • Lieber, A.1    He, C.Y.2    Meuse, L.3    Schowalter, D.4    Kirillova, I.5    Winther, B.6    Kay, M.A.7
  • 56
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP, Wilson JM, Batshaw ML. 2003. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 80:148-158. https://doi.org/10.1016/j.ymgme .2003.08.016.
    • (2003) Mol Genet Metab , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6    Wilson, J.M.7    Batshaw, M.L.8
  • 59
    • 34547434066 scopus 로고    scopus 로고
    • Use of the Syrian hamster as an animal model for oncolytic adenovirus vectors
    • Thomas MA, Spencer JF, Wold WSM. 2007. Use of the Syrian hamster as an animal model for oncolytic adenovirus vectors. Methods Mol Med 130:169-183. https://doi.org/10.1385/1-59745-166-5:169.
    • (2007) Methods Mol Med , vol.130 , pp. 169-183
    • Thomas, M.A.1    Spencer, J.F.2    Wold, W.S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.