Lack of an Association between the SDF-1 rs1801157 Polymorphism and Coronary Heart Disease: A Meta-Analysis

Scientific Reports

Volumn 5, Issue 1, 2015, Pages

  Wu, Nan ^a   Zhang, Xiaowen ^b   Jia, Pengyu ^b   Jia, Dalin ^a  

^a First Affiliated Hospital of China Medical University   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL12 PROTEIN, HUMAN; STROMAL CELL DERIVED FACTOR 1;

ASIAN CONTINENTAL ANCESTRY GROUP; CAUCASIAN; CORONARY ARTERY DISEASE; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; HEART INFARCTION; HUMAN; META ANALYSIS; PATHOLOGY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; CHEMOKINE CXCL12; CORONARY DISEASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 85018222845     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/SREP11803     Document Type: Article

References (40)

1. Mathers C. D. & Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3, e442 (2006).
2. Lusis A. J. Atherosclerosis. Nature 407, 233–241 (2000).
3. Madjid M. & Willerson, J. T. Inflammatory markers in coronary heart disease. Brit Med Bull 100, 23–38 (2010).
4. Ross R. Atherosclerosis–an inflammatory disease. New Engl J Med 340, 115–126 (1999).
5. Tedgui A. & Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory Pathways. Physiol Rev 86, 515–581 (2006).
6. Alam S. E., Nasser S. S., Fernainy K. E., Habib A. A. & Badr K. F. Cytokine imbalance in acute coronary syndrome. Curr Opin Pharmacol 4, 166–170 (2004).
7. Bleul C. C., Fuhlbrigge R. C., Casasnovas J. M., Aiuti A. & Springer T. A. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 184, 1101–1109 (1996).
8. Zgraggen S., Huggenberger R., Kerl K. & Detmar M. An important role of the SDF-1/CXCR4 axis in chronic skin inflammation. PLoS One 9, e93665 (2014).
9. Zou Y. R., Kottmann A. H., Kuroda M., Taniuchi I. & Littman D. R. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393, 595–599 (1998).
10. Sun Y., et al. CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis. Tumour Biol 35, 7765–7773 (2014).
11. Ratajczak M. Z. et al. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis. Leukemia 20:1915–1924 (2006).
12. Ho T. K., Shiwen X., Abraham D., Tsui J. & Baker D. Stromal-Cell-Derived Factor-1 (SDF-1)/CXCL12 as Potential Target of Therapeutic Angiogenesis in Critical Leg Ischaemia. Cardiol Res Pract 2012, 143209 (2012).
13. Abi-Younes S. et al. The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques. Circ Res 86, 131–138 (2000).
14. Liehn E. A. et al. Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J Am Coll Cardiol 58, 2415–2423 (2011).
15. Subramanian S. et al. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol 34, 2100–2105 (2014).
16. Samani N. J. et al. Genomewide association analysis of coronary artery disease. New Engl J Med 357, 443–453 (2007).
17. Myocardial Infarction Genetics Consortium, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 41, 334–341 (2009).
18. Huang Y. et al. Relationship between chemokine (C-X-C motif ) ligand 12 gene variant and coronary heart disease: case-control study and meta-analysis. Gene 521, 38–44 (2013).
19. Winkler C. et al. Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC). Science 279, 389–393 (1998).
20. Feng L. et al. A single nucleotide polymorphism in the stromal cell-derived factor 1 gene is associated with coronary heart disease in Chinese patients. Int J Mol Sci 15, 11054–11063 (2014).
21. Gu X. L. et al. Polymorphism of stromal cell-derived factor-1 selectively upregulates gene expression and is associated with increased susceptibility to coronary artery disease. Biochem Bioph Res Co 443, 932–937 (2014).
22. Szalai C. et al. Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD). Coincidence of elevated Lp(a) and MCP-1-2518 G/G genotype in CAD patients. Atherosclerosis 158, 233–239 (2001).
23. Tunstall-Pedoe H. et al. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation 90, 583–612 (1994).
24. Zhang B. C., Li W. M. & Xu Y. W. A meta-analysis of the association of adiponectin gene polymorphisms with coronary heart disease in Chinese Han population. Clin Endocrinol 76, 358–364 (2012).
25. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25, 603–605 (2010).
26. Luan B., Han Y., Zhang X., Kang J. & Yan C. Association of the SDF1-3’A polymorphism with susceptibility to myocardial infarction in Chinese Han population. Mol Biol Rep 37, 399–403 (2010).
27. Borghini A. et al. Stromal cell-derived factor-1-3’A polymorphism is associated with decreased risk of myocardial infarction and early endothelial disturbance. J Cardiovasc Med 15, 710–716 (2014).
28. Apostolakis S. et al. Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery disease. Thromb Res 119, 63–71 (2007).
29. Simeoni E. et al. Association of RANTES G-403A gene polymorphism with increased risk of coronary arteriosclerosis. Eur Heart J 25, 1438–1446 (2004).
30. Zernecke A. et al. Protective role Of CXC receptor 4/CXC ligand 12 unveils the importance of neu trophils in atherosclerosis. Circ Res 102, 209–217 (2008).
31. Damås J. K. et al. Stromal cell-derived factor-1alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects. Circulation 106, 36–42 (2002).
32. Hu X. et al. Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: Role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation 116, 654–663 (2007).
33. Saxena A. et al. Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation 117, 2224– 2231(2008).
34. Jang Y. H. et al. Stromal cell derived factor-1 (SDF-1) targeting reperfusion reduces myocardial infarction in isolated rat hearts. Cardiovasc Ther 30, 264–272 (2012).
35. Hirata H. et al. CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility. Clin Cancer Res 13, 5056–5062 (2007).
36. Gong H. et al. The CXCL12 G801A polymorphism and cancer risk: evidence from 17 case-control studies. Gene 509, 228–231 (2012).
37. Wu F. X. et al. Association of chemokine CXCL12-3’G801A polymorphism with systemic lupus erythematosus in a Han Chinese population. Lupus 21, 604–610 (2012).
38. Selvaraj P., Alagarasu K. & Singh B. Stromal cell-derived factor-1 (SDF-1/CXCL12) gene polymorphisms in pulmonary tuberculosis patients of south India. Int J Immunogenet 39, 26–31 (2012).
39. Ioannidis J. P., Ntzani E. E., Trikalinos T. A. & Contopoulos-Ioannidis D. G. Replication validity of genetic association studies. Nat Genet 29, 306–309 (2001).
40. Schmid C. H., Stark P. C., Berlin J. A., Landais P. & Lau J. Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors. J Clin Epidemiol 57, 683–697 (2004).