An exploration of heterogeneity in genetic analysis of complex pedigrees: Linkage and association using whole genome sequencing data in the MAP4 region

BMC Proceedings

Volumn 8, Issue , 2014, Pages

  Bull, Shelley B ^a,b   Chen, Zhijian ^a   Tan, Kuan Rui ^b   Poirier, Julia ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME 3; CONFERENCE PAPER; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINKAGE; HUMAN; MAP4 REGION; MEXICAN AMERICAN; PEDIGREE ANALYSIS; SIMULATION; SYSTOLIC BLOOD PRESSURE; WHOLE GENOME SEQUENCING;

EID: 85018193183     PISSN: None     EISSN: 17536561     Source Type: Journal    
DOI: 10.1186/1753-6561-8-S1-S107     Document Type: Conference Paper

References (6)

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3. Chen Z, Tan KR, Bull SB: Multiphase analysis by linkage, quantitative transmission disequilibrium, and measured genotype: systolic blood pressure in complex Mexican American pedigrees. BMC Proc. 2014, 8 (Suppl 1): S108-
4. Almasy L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet. 1998, 62: 1198-1211. 10.1086/301844.
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6. Kent JW, Dyer TD, Göring HH, Blangero J: Type I error rates in association versus joint linkage/association tests in related individuals. Genet Epidemiol. 2007, 31: 173-177. 10.1002/gepi.20200.