Over-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancer

Oncotarget

Volumn 8, Issue 16, 2017, Pages 25977-25988

  Jin, Cheng ^a   Yuan, Feng Lai ^a   Gu, Yuan Long ^a   Li, Xia ^a   Liu, Min Feng ^a   Shen, Xiao Min ^a   Liu, Bo ^a   Zhu, Mao Qun ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

ASIC1a; CRISPR CAS9; Liver cancer; Proliferation; catenin

Indexed keywords

ACID SENSING ION CHANNEL 1A; BETA CATENIN; LYMPHOID ENHANCER FACTOR T CELL FACTOR; ONCOPROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG; ACID SENSING ION CHANNEL; ASIC1 PROTEIN, HUMAN; T CELL FACTOR PROTEIN;

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CARCINOGENICITY; CELL CYCLE ARREST; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; CRISPR CAS SYSTEM; DISEASE ASSOCIATION; FEMALE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; CELL CYCLE; DISEASE MODEL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE KNOCKOUT; GENETICS; KAPLAN MEIER METHOD; LIVER TUMOR; METABOLISM; MORTALITY; MOUSE; PATHOLOGY; PROGNOSIS; TUMOR CELL LINE; XENOGRAFT;

ACID SENSING ION CHANNELS; ANIMALS; APOPTOSIS; BETA CATENIN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKOUT TECHNIQUES; HETEROGRAFTS; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; MALE; MICE; MODELS, BIOLOGICAL; NEOPLASM STAGING; PROGNOSIS; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS;

EID: 85017524686     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10774     Document Type: Article

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