The life course implications of ready to use therapeutic food for children in low-income countries

International Journal of Environmental Research and Public Health

Volumn 14, Issue 4, 2017, Pages

  Bazzano, Alessandra N ^a,b   Potts, Kaitlin S ^a   Bazzano, Lydia A ^a   Mason, John B ^a  

^a TULANE UNIVERSITY   (United States)

^b TULANE UNIVERSITY   (United States)

Author keywords

Child; Malnutrition; Maternal; Ready to use therapeutic food (RUTF); Undernutrition

Indexed keywords

CALORIC INTAKE; DIET SUPPLEMENTATION; DIET THERAPY; DIETARY SUPPLEMENT; DROUGHT; ENVIRONMENTAL SUSTAINABILITY; FOOD INDUSTRY; FOOD INSECURITY; HEALTH CARE COST; HUMAN; INTESTINE FLORA; LOW INCOME COUNTRY; MALNUTRITION; MATERNAL NUTRITION; NOTE; NUTRITIONAL COUNSELING; READY TO USE THERAPEUTIC FOOD; TASTE PREFERENCE; THERAPY EFFECT; CHILD NUTRITION DISORDERS; DEVELOPING COUNTRY; EMERGENCY; FEMALE; INFANT; MALE; NUTRITIONAL STATUS; POVERTY; PREGNANCY; PRESCHOOL CHILD;

CHILD NUTRITION DISORDERS; CHILD, PRESCHOOL; DEVELOPING COUNTRIES; DIETARY SUPPLEMENTS; EMERGENCIES; ENERGY INTAKE; FEMALE; HUMANS; INFANT; MALE; MALNUTRITION; NUTRITIONAL STATUS; POVERTY; PREGNANCY;

EID: 85017500083     PISSN: 16617827     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph14040403     Document Type: Note

References (137)

1. Black, R.E.; Victora, C.G.; Walker, S.P.; Bhutta, Z.A.; Christian, P.; de Onis, M.; Ezzati, M.; Grantham-McGregor, S.; Katz, J.; Martorell, R.; et al. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet 2013, 382, 427–451. [CrossRef]
2. World Health Oganization; World Bank Group; UNICEF. Levels and Trends in Child Malnutrition; World Health Organization: Geneva, Switzerland, 2015.
3. World Health Organization. Management of Severe Malnutrition: A Manual for Physicians and Other Senior Health Workers; World Health Organization: Geneva, Switzerland, 1999.
4. Ashworth, A.; Khanum, S.; Jackson, A.; Schofield, C. Guidelines for the Inpatient Treatment of Severely Malnourished Children; World Health Organization: Geneva, Switzerland, 2003.
5. World Health Organization. Severe Malnutrition: Report of a Consultation to Review Current Literature; World Health Organization: Geneva, Switzerland, 2004.
6. World Health Organization. Management of the Child with a Serious Infection or Severe Malnutrition: Guidelines for Care at the First-Referral Level in Developing Countries; World Health Organization: Geneva, Switzerland, 2000.
7. World Health Organization. Guideline: Updates on the Management of Severe Acute Malnutrition in Infants and Children; World Health Organization: Geneva, Switzerland, 2013.
8. World Health Organization; World Food Programme; United Nations System Standing Committee on Nutrition; UNICEF. Community-Based Management of Severe Acute Malnutrition. A Joint Statement by the World Health Organization, the World Food Programme, the United Nations System Standing Committee on Nutrition and the United Nations Children’s Fund; World Health Organization: Geneva, Switzerland, 2007.
9. Briend, A.; Lacsala, R.; Prudhon, C.; Mounier, B.; Grellety, Y.; Golden, M.H.N. Ready-to-use therapeutic food for treatment of marasmus. Lancet 1999, 353, 1767–1768. [CrossRef]
10. Amthor, R.E.; Cole, S.M.; Manary, M.J. The use of home-based therapy with ready-to-use therapeutic food to treat malnutrition in a rural area during a food crisis. J. Am. Diet. Assoc. 2009, 109, 464–467. [CrossRef] [PubMed]
11. Ciliberto, M.A.; Sandige, H.; Ndekha, M.J.; Ashorn, P.; Briend, A.; Ciliberto, H.M.; Manary, M.J. Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: A controlled, clinical effectiveness trial. Am. J. Clin. Nutr. 2005, 81, 864–870. [PubMed]
12. Lazzerini, M.; Rubert, L.; Pani, P. Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income countries. Cochrane Database Syst. Rev. 2013, 6, Cd009584.
13. Linneman, Z.; Matilsky, D.; Ndekha, M.; Manary, M.J.; Maleta, K.; Manary, M.J. A large-scale operational study of home-based therapy with ready-to-use therapeutic food in childhood malnutrition in Malawi. Matern. Child Nutr. 2007, 3, 206–215. [CrossRef] [PubMed]
14. Collins, S.; Sadler, K. Outpatient care for severely malnourished children in emergency relief programmes: A retrospective cohort study. Lancet 2002, 360, 1824–1830. [CrossRef]
15. Diop el, H.I.; Dossou, N.I.; Ndour, M.M.; Briend, A.; Wade, S. Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial. Am. J. Clin. Nutr. 2003, 78, 302–307. [PubMed]
16. Tadesse, E.; Ekström, E.-C.; Berhane, Y. Challenges in implementing the integrated community-based outpatient therapeutic program for severely malnourished children in rural southern Etiopia. Nutrients 2016, 8, 251. [CrossRef] [PubMed]
17. UNICEF; Coverage Monitoring Network; ACF International. The State of Global SAM Management Coverage 2012; UNICEF: New York, NY, USA; London, UK, 2012.
18. UNICEF. Position Paper: Ready-To-Use Therapeutic Food for Children with Severe Acute Malnutrition in UNICEF Position Paper; United Nations Children’s Fund: New York, NY, USA, 2013.
19. Briend, A. Highly nutrient-dense spreads: A new approach to delivering multiple micronutrients to high-risk groups. Br. J. Nutr. 2001, 85 (Suppl. 2), S175–S179. [CrossRef] [PubMed]
20. ® Patent Now Accessible On-Line. October 2010. Available online: http://www.nutriset.fr/accordusage (accessed on 1 February 2017).
21. Nutriset. The PlumpyField Network: How It Works. Available online: http://www.nutriset.fr/en/plumpyfield/plumpyfield-how-it-works.html (accessed on 8 August 2016).
22. ®. PlumpyField with Nutriset: Key Data: Production by the Members of the Network. Available online: http://www.plumpyfield.com/about/key-data (accessed on 16 August 2016).
23. Rice, A. The Peanut Solution; New York Times: New York, NY, USA, 2010.
24. Manary, M.J. Local production and provision of ready-to-use therapeutic food (RUTF) spread for the treatment of severe childhood malnutrition. Food Nutr. Bull. 2006, 27 (Suppl. 3), S83–S89. [CrossRef] [PubMed]
25. UNICEF Supply Division. Supplies and Logistics: Committment to Transparency. 28 May 2014. Available online: http://www.unicef.org/supply/index_62310.html (accessed on 16 August 2016).
26. UNICEF Supply Division. UNICEF: Ready-To-Use Therapeutic Food Demand. 5 February 2015. Available online: http://www.unicef.org/supply/files/UNICEF_RUTF_Demand.pdf (accessed on 16 August 2016).
27. UNICEF Supply Division. Ready-To-Use Therapeutic Food: Current Outlook; UNICEF: Geneva, Switzerland, 2014.
28. UNICEF. Ready-To-Use Therapeutic Food Price Data. 25 July 2016. Available online: http://www.unicef. org/supply/index_59716.html (accessed on 16 August 2016).
29. Nutriset. Product Range: Nutritional Solutions by Nutriset. Available online: http://www.nutriset.fr/en/product-range/nutriset-product-range.html (accessed on 16 August 2016).
30. UNICEF Evaluation Office. Evaluation of Community Management of Acute Malnutrition: Global Synthesis Report; United Nations Children’s Fund: New York, NY, USA, 2013.
31. Partners in Health. Nourimanba: Fighting Malnutrition, Fightling Poverty in Haiti. 2 October 2013. Available online: http://www.pih.org/blog/nourimanba-malnutrition-haiti-poverty (accessed on 23 August 2016).
32. “Miracle’ Food Saves Lives” 60 Minutes News. CBS News television broadcast. Originally aired 22 June 2008.
33. Edesia Nutrition. Edesia Nutrition. Available online: https://www.edesianutrition.org/(accessed on 16 August 2016).
34. Edesia Nutrition. Edesia Nutrition: The Foods. Available online: https://www.edesianutrition.org/the-foods/(accessed on 16 August 2016).
35. Edesia Nutrition. Annual Report 2014: Edesia Global Nutrition Solutions. 2015. Available online: http://www.edesianutrition.org/wp-content/uploads/2016/01/annualreport2014.pdf (accessed on 16 August 2016).
36. Edesia Nutrition. Our Current Openings: Business Development Manager. 2016. Available online: http://www.edesianutrition.org/wp-content/uploads/2016/05/busdevmanager052316.pdf (accessed on 16 August 2016).
37. Reed, H. Plumpy’Nut and a Mother’s Love. Available online: https://www.edesianutrition.org/plumpynut-and-a-mothers-love/(accessed on 16 August 2016).
38. Mana Nutritive Aid Products Incorporated; Moore, M.; Tilley, P. Tax Form 990: Return of Organization Exempt from Income Tax (Public Discolsure Copy). 2016. Available online: http://mananutrition.org/images/annualreport/2014-MANA-990.pdf (accessed on 1 February 2017).
39. Valid Nutrition. Valid Nutrition: Our Products. 2016. Available online: http://www.validnutrition.org/our-products/(accessed on 16 August 2016).
40. Valid Nutrition. Valid Nutrition: Annual Review of 2015. February 2016. Available online: http://www. validnutrition.org/wp-content/uploads/2016/03/Annual-Report-2015-Final-.pdf (accessed on 16 August 2016).
41. Amul. Amul Homepage. 2016. Available online: http://www.amul.com/pdf (accessed on 16 August 2016).
42. Koch, F. Change Leader Interview: Dr. Steve Collins. 2016. Available online: http://www.ashoka.ie/media/2016/1/13/change-leader-interview-dr-steve-collins (accessed on 16 August 2016).
43. Valid International. VALID International Homepage. Available online: http://www.validinternational.org/(accessed on 16 August 2016).
44. This Bar Saves Lives. This Bar Saves Lives Homepage. 2016. Available online: http://www.thisbarsaveslives. com/(accessed on 16 August 2016).
45. This Bar Saves Lives. This Bar Saves Lives: What We’re about. 4 June 2014. Available online: https://www.youtube.com/watch?v=jqfqGhoT1HQ (accessed on 16 August 2016).
46. This Bar Saves Lives. Our Cause. 2016. Available online: http://www.thisbarsaveslives.com/pages/our-cause (accessed on 16 August 2016).
47. Calorie Cloud. Calorie Cloud Homepage. 2016. Available online: http://caloriecloud.org/(accessed on 16 August 2016).
48. Toddler Food Partners. Toddler Food Partners: Helping Malnourished Children (Homepage). Available online: http://toddlerfoodpartners.org/index.php (accessed on 16 August 2016).
49. Lissner, J. Merchants of Misery; New Internationalist: Oxford, UK, 1981.
50. Hilary, J. The Unwelcome Return of Development Pornography; The New Internationalist: Oxford, UK, 2014.
51. CONCORD: European NGO Confederation for Relief and Development. Code of Conduct on Images and Messages; Dochas: Dublin, Ireland, 2006.
52. Dochas: The Irish Association of Non-Governmental Development Organisations. The Illustrative Guide to the Dochas Code of Conduct on Images and Messages; The Irish Association of Non-Governmental Development Organisations: Dublin, Ireland, 2014.
53. Sachs, J. Saying “Nuts” to Hunger. In The Blog; Huffington Post: New York, NY, USA, 2010; Available online: http://www.huffingtonpost.com/jeffrey-sachs/saying-nuts-to-hunger_b_706798.html (accessed on 16 August 2016).
54. Godfrey, K.M.; Gluckman, P.D.; Hanson, M.A. Developmental origins of metabolic disease: Life course and intergenerational perspectives. Trends Endocrinol. Metab. 2010, 21, 199–205. [CrossRef] [PubMed]
55. Correia-Branco, A.; Keating, E.; Martel, F. Maternal undernutrition and fetal developmental programming of obesity: The glucocorticoid connection. Reprod. Sci. 2015, 22, 138–145. [CrossRef] [PubMed]
56. McMillen, I.C.; Robinson, J.S. Developmental origins of the metabolic syndrome: Prediction, plasticity, and programming. Physiol. Rev. 2005, 85, 571–633. [CrossRef] [PubMed]
57. Milovanovic, I.; Njuieyon, F.; Deghmoun, S.; Chevenne, D.; Levy-Marchal, C.; Beltrand, J. SGA children with moderate catch-up growth are showing the impaired insulin secretion at the age of 4. PLoS ONE 2014, 9, e100337. [CrossRef] [PubMed]
58. Somasse, Y.E.; Dramaix, M.; Bahwere, P.; Donnen, P. Relapses from acute malnutrition and related factors in a community-based management programme in Burkina Faso. Matern. Child Nutr. 2015, 12, 908–917. [CrossRef] [PubMed]
59. Schoonees, A.; Lombard, M.; Musekiwa, A.; Nel, E.; Volmink, J. Ready-to-use therapeutic food for home-based treatment of severe acute malnutrition in children from six months to five years of age. Cochrane Database Syst. Rev. 2013, 6, CD009000.
60. Lussana, F.; Painter, R.; Ocke, M.C.; Buller, H.R.; Bossuyt, P.M.; Roseboom, T.J. Prenatal exposure to the Dutch famine is associated with a preference for fatty foods and a more atherogenic lipid profile. Am. J. Clin. Nutr. 2008, 88, 1648–1652. [CrossRef] [PubMed]
61. Uauy, R.; Kain, J. The epidemiological transition: Need to incorporate obesity prevention into nutrition programmes. Public Health Nutr. 2002, 5, 223–229. [CrossRef] [PubMed]
62. Ekelund, U.; Ong, K.; Linne, Y.; Neovius, M.; Brage, S.; Dunger, D.B.; Wareham, N.J.; Rossner, S. Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: The Stockholm Weight Development Study (SWEDES). Am. J. Clin. Nutr. 2006, 83, 324–330. [PubMed]
63. Gordon-Larsen, P.; Jones-Smith, J. Challenges in ameliorating hunger while preventing obesity. Lancet 2012, 380, 787–789. [CrossRef]
64. Adair, L.S.; Fall, C.H.; Osmond, C.; Stein, A.D.; Martorell, R.; Ramirez-Zea, M.; Sachdev, H.S.; Dahly, D.L.; Bas, I.; Norris, S.A.; et al. Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income: Findings from five birth cohort studies. Lancet 2013, 382, 525–534. [CrossRef]
65. Victora, C.G.; Sibbritt, D.; Horta, B.L.; Lima, R.C.; Cole, T.; Wells, J. Weight gain in childhood and body composition at 18 years of age in Brazilian males. Acta Paediatr. 2007, 96, 296–300. [CrossRef] [PubMed]
66. World Health Organization. Integrated Management of Childhood Illness: Distance Learnign Course. Module 6: Malnutrition and Anaemia; World Health Organization: Geneva, Switzerland, 2014.
67. Nutrition Wing Ministry of Health Government of Pakistan; UNICEF; World Health Organization; Save the Children USA. National Guidelines for the Management of Acute Malnutrition among Children under Five and Pregnant and Lactating Women; Ministry of Health: Lahore, Pakistan, 2010.
68. Food and Nutrition Technical Assistance. Trainers Guide: Community-Based Management of Acute Malnutrition: Module Four: Outpatient Care for the Management of SAM without Medical Complications; Food and Nutrition Technical Assistance, USAID: Washington, DC, USA, 2008.
69. Davis, C. Self-selection of diets by newly-weaned infants. Am. J. Dis. Child 1928, 36, 651–679. [CrossRef]
70. Davis, C.M. Results of the self selection of diets by young children. Can. Med. Assoc. J. 1939, 41, 257–261. [PubMed]
71. Rozin, P.; Vollmecke, T.A. Food likes and dislikes. Annu. Rev. Nutr. 1986, 6, 433–456. [CrossRef] [PubMed]
72. Nicklaus, S.; Boggio, V.; Chabanet, C.; Issanchou, S. A prospective study of food variety seeking in childhood, adolescence and early adult life. Appetite 2005, 44, 289–297. [CrossRef] [PubMed]
73. Nicklaus, S.; Chabanet, C.; Boggio, V.; Issanchou, S. Food choices at lunch during the third year of life: Increase in energy intake but decrease in variety. Acta Paediatr. 2005, 94, 1023–1029. [CrossRef] [PubMed]
74. Nicklaus, S. Development of food variety in children. Appetite 2009, 52, 253–255. [CrossRef] [PubMed]
75. Rigal, N.; Reiter, F.; Morice, C.; De Boissieu, D.; Dupont, C. Food allergy in the child: An exploratory study on the impact of the elimination diet on food neophobia. Arch. Pediatr. 2005, 12, 1714–1720. [CrossRef] [PubMed]
76. Birch, L.L.; Marlin, D.W. I don’t like it; I never tried it: Effects of exposure on two-year-old children’s food preferences. Appetite 1982, 3, 353–360. [CrossRef]
77. Birch, L.L.; McPhee, L.; Shoba, B.C.; Pirok, E.; Steinberg, L. What kind of exposure reduces children’s food neophobia? Looking vs. tasting. Appetite 1987, 9, 171–178. [CrossRef]
78. Pliner, P. The effects of mere exposure on liking for edible substances. Appetite 1982, 3, 283–290. [CrossRef]
79. Shomaker, L.B.; Tanofsky-Kraff, M.; Zocca, J.M.; Courville, A.; Kozlosky, M.; Columbo, K.M.; Wolkoff, L.E.; Brady, S.M.; Crocker, M.K.; Ali, A.H.; et al. Eating in the absence of hunger in adolescents: Intake after a large-array meal compared with that after a standardized meal. Am. J. Clin. Nutr. 2010, 92, 697–703. [CrossRef] [PubMed]
80. Zheng, H.; Lenard, N.R.; Shin, A.C.; Berthoud, H.R. Appetite control and energy balance regulation in the modern world: Reward-driven brain overrides repletion signals. Int. J. Obes. 2009, 33 (Suppl. 2), S8–S13. [CrossRef] [PubMed]
81. Sunday, S.R.; Sanders, S.A.; Collier, G. Palatability and meal patterns. Physiol. Behav. 1983, 30, 915–918. [CrossRef]
82. Wang, G.J.; Volkow, N.D.; Telang, F.; Jayne, M.; Ma, J.; Rao, M.; Zhu, W.; Wong, C.T.; Pappas, N.R.; Geliebter, A.; et al. Exposure to appetitive food stimuli markedly activates the human brain. Neuroimage 2004, 21, 1790–1797. [CrossRef] [PubMed]
83. Wang, G.J.; Volkow, N.D.; Thanos, P.K.; Fowler, J.S. Similarity between obesity and drug addiction as assessed by neurofunctional imaging: A concept review. J. Addict. Dis. 2004, 23, 39–53. [CrossRef] [PubMed]
84. Macht, M.; Mueller, J. Immediate effects of chocolate on experimentally induced mood states. Appetite 2007, 49, 667–674. [CrossRef] [PubMed]
85. Kenny, P.J. Reward mechanisms in obesity: New insights and future directions. Neuron 2011, 69, 664–679. [CrossRef] [PubMed]
86. Cornelius, J.R.; Tippmann-Peikert, M.; Slocumb, N.L.; Frerichs, C.F.; Silber, M.H. Impulse control disorders with the use of dopaminergic agents in restless legs syndrome: A case-control study. Sleep 2010, 33, 81–87. [PubMed]
87. Rolls, E.T. Taste, olfactory and food texture reward processing in the brain and obesity. Int. J. Obes. 2011, 35, 550–561. [CrossRef] [PubMed]
88. Small, D.M. Taste representation in the human insula. Brain Struct Funct. 2010, 214, 551–561. [CrossRef] [PubMed]
89. Berridge, K.C. ‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders. Physiol. Behav. 2009, 97, 537–550. [CrossRef] [PubMed]
90. Dagher, A. The neurobiology of appetite: Hunger as addiction. Int. J. Obes. 2009, 33 (Suppl. 2), S30–S33. [CrossRef] [PubMed]
91. Gahagan, S. The Development of Eating Behavior—Biology and Context. J. Dev. Behav. Pediatr. 2012, 33, 261–271. [CrossRef] [PubMed]
92. Cho, I.; Blaser, M.J. The human microbiome: At the interface of health and disease. Nat. Rev. Genet. 2012, 13, 260–270. [CrossRef] [PubMed]
93. Baumann, P.; Moran, N.A. Non-cultivable microorganisms from symbiotic associations of insects and other hosts. Antonie Leeuwenhoek 1997, 72, 39–48. [CrossRef] [PubMed]
94. Matthews, K.A.; Zhu, S.; Tucker, D.C.; Whooley, M.A. Blood pressure reactivity to psychological stress and coronary calcification in the Coronary Artery Risk Development in Young Adults Study. Hypertension 2006, 47, 391–395. [CrossRef] [PubMed]
95. Turnbaugh, P.J.; Hamady, M.; Yatsunenko, T.; Cantarel, B.L.; Duncan, A.; Ley, R.E.; Sogin, M.L.; Jones, W.J.; Roe, B.A.; Affourtit, J.P.; et al. A core gut microbiome in obese and lean twins. Nature 2009, 457, 480–484. [CrossRef] [PubMed]
96. Zhang, H.; DiBaise, J.K.; Zuccolo, A.; Kudrna, D.; Braidotti, M.; Yu, Y.; Parameswaran, P.; Crowell, M.D.; Wing, R.; Rittmann, B.E.; et al. Human gut microbiota in obesity and after gastric bypass. Proc. Natl. Acad. Sci. USA 2009, 106, 2365–2370. [CrossRef] [PubMed]
97. Furet, J.; Kong, L.C.; Tap, J.; Poitou, C.; Basdevant, A.; Bouillot, J.L.; Mariat, D.; Corthier, G.; Dore, J.; Henegar, C.; et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: Links with metabolic and low-grade inflammation markers. Diabetes 2010, 59, 3049–3057. [CrossRef] [PubMed]
98. Greenblum, S.; Turnbaugh, P.J.; Borenstein, E. Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease. Proc. Natl. Acad. Sci. USA 2012, 109, 594–599. [CrossRef] [PubMed]
99. Le Chatelier, E.; Nielsen, T.; Qin, J.; Prifti, E.; Hildebrand, F.; Falony, G.; Almeida, M.; Arumugam, M.; Batto, J.M.; Kennedy, S.; et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013, 500, 541–546. [CrossRef] [PubMed]
100. Larsen, N.; Vogensen, F.K.; van den Berg, F.W.; Nielsen, D.S.; Andreasen, A.S.; Pedersen, B.K.; Al-Soud, W.A.; Sorensen, S.J.; Hansen, L.H.; Jakobsen, M. Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults. PLoS ONE 2010, 5, e9085. [CrossRef] [PubMed]
101. Qin, J.; Li, Y.; Cai, Z.; Li, S.; Zhu, J.; Zhang, F.; Liang, S.; Zhang, W.; Guan, Y.; Shen, D.; et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012, 490, 55–60. [CrossRef] [PubMed]
102. Karlsson, F.H.; Tremaroli, V.; Nookaew, I.; Bergstrom, G.; Behre, C.J.; Fagerberg, B.; Nielsen, J.; Backhed, F. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature 2013, 498, 99–103. [CrossRef] [PubMed]
103. Serino, M.; Fernandez-Real, J.M.; Garcia-Fuentes, E.; Queipo-Ortuno, M.; Moreno-Navarrete, J.M.; Sanchez, A.; Burcelin, R.; Tinahones, F. The gut microbiota profile is associated with insulin action in humans. Acta Diabetol. 2013, 50, 753–761. [CrossRef] [PubMed]
104. Texeira, F.S.; Grzeskowiak, L.M.; Salminen, S.; Laitinen, K.; Bressan, J.; Gouveia Peluzio Mdo, C. Faecal levels of Bifidobacterium and Clostridium coccoides but not plasma lipopolysaccharide are inversely related to insulin and HOMA index in women. Clin. Nutr. 2013, 32, 1017–1022. [CrossRef] [PubMed]
105. Zhang, X.; Shen, D.; Fang, Z.; Jie, Z.; Qiu, X.; Zhang, C.; Chen, Y.; Ji, L. Human gut microbiota changes reveal the progression of glucose intolerance. PLoS ONE 2013, 8, e71108. [CrossRef] [PubMed]
106. Joyce, S.; MacSharry, J.; Casey, P.G.; Kinsella, M.; Murphy, E.F.; Shanahan, F.; Hill, C.; Gahan, C.G.M. Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut. Proc. Natl. Acad. Sci. USA 2014, 111, 7421–7426. [CrossRef] [PubMed]
107. Ridaura, V.K.; Faith, J.J.; Rey, F.E.; Cheng, J.; Duncan, A.E.; Kau, A.L.; Griffin, N.W.; Lombard, V.; Henrissat, B.; Bain, J.R.; et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013, 341, 1241214. [CrossRef] [PubMed]
108. Ellekilde, M.; Selfjord, E.; Larsen, C.S.; Jakesevic, M.; Rune, I.; Tranberg, B.; Vogensen, F.K.; Nielsen, D.S.; Bahl, M.I.; Licht, T.R.; et al. Transfer of gut microbiota from lean and obese mice to antibiotic-treated mice. Sci. Rep. 2014, 4, 5922. [CrossRef] [PubMed]
109. Turnbaugh, P.J.; Ley, R.E.; Mahowald, M.A.; Magrini, V.; Mardis, E.R.; Gordon, J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444, 1027–1031. [CrossRef] [PubMed]
110. Vrieze, A.; Van Nood, E.; Holleman, F.; Salojarvi, J.; Kootte, R.S.; Bartelsman, J.F.; Dallinga-Thie, G.M.; Ackermans, M.T.; Serlie, M.J.; Oozeer, R.; et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology 2012, 143, 913.e7–916.e7. [CrossRef] [PubMed]
111. Alcock, J.; Maley, C.; Aktipis, A. Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms. BioEssays 2016, 36, 940–949. [CrossRef] [PubMed]
112. Cox, A.J.; West, N.P.; Cripps, A.W. Obesity, inflammation, and the gut microbiota. Lancet Diabetes Endocrinol. 2015, 3, 207–215. [CrossRef]
113. Cani, P.D.; Osto, M.; Geurts, L.; Everard, A. Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity. Gut Microbes 2012, 3, 279–288. [CrossRef] [PubMed]
114. Kallus, S.J.; Brandt, L.J. The intestinal microbiota and obesity. J. Clin. Gastroenterol. 2012, 46, 16–24. [CrossRef] [PubMed]
115. Smith, M.I.; Yatsunenko, T.; Manary, M.J.; Trehan, I.; Mkakosya, R.; Cheng, J.; Kau, A.L.; Rich, S.S.; Concannon, P.; Mychaleckyj, J.C.; et al. Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor. Science 2013, 339, 548–554. [CrossRef] [PubMed]
116. Relman, D.A. Undernutrition—Looking Within for Answers. Science 2013, 339, 530–532. [CrossRef] [PubMed]
117. Ashworth, A.; Ferguson, E. Dietary counseling in the management of moderate malnourishment in children. Food Nutr. Bull. 2009, 30 (Suppl. 3), S405–S433. [CrossRef] [PubMed]
118. Mason, J.B.; Hay, R.W.; Leresche, J.; Peel, S.; Darley, S. Treatment of severe malnutrition in relief. Lancet 1974, 303, 332–335. [CrossRef]
119. Khanum, S. A Comparison of the Cost-Effectiveness of Alternative Approaches to the Treatment of Severly Malnourished Childrend. Ph.D. Thesis, London School of Hygiene & Tropical Medicine, London, UK, 1994.
120. Greco, L.; Balungi, J.; Amono, K.; Iriso, R.; Corrado, B. Effect of a low-cost food on the recovery and death rate of malnourished children. J. Pediatr. Gastroenterol. Nutr. 2006, 43, 512–517. [CrossRef] [PubMed]
121. Mamidi, R.S.; Kulkarni, B.; Radhakrishna, K.V.; Shatrugna, V. Hospital based nutrition rehabilitation of severely undernourished children using energy dense local foods. Indian Pediatr. 2010, 47, 687–693. [CrossRef] [PubMed]
122. Ashworth, A. Efficacy and effectiveness of community-based treatment of severe malnutrition. Food Nutr. Bull. 2006, 27 (Suppl. 3), S24–S48. [CrossRef] [PubMed]
123. Fahmida, U.; Kolopaking, R.; Santika, O.; Sriani, S.; Umar, J.; Htet, M.K.; Ferguson, E. Effectiveness in improving knowledge, practices, and intakes of “key problem nutrients” of a complementary feeding intervention developed by using linear programming: Experience in lombok, indonesia. Am. J. Clin. Nutr. 2015, 101, 455–461. [CrossRef] [PubMed]
124. Ahmed, T.; Choudhury, N.; Hossain, M.I.; Tangsuphoom, N.; Islam, M.M.; de Pee, S.; Steiger, G.; Fuli, R.; Sarker, S.A.; Parveen, M.; et al. Development and acceptability testing of ready-to-use supplementary food made from locally available food ingredients in bangladesh. BMC Pediatr. 2014, 14, 164. [CrossRef] [PubMed]
125. Hlaing, L.M.; Fahmida, U.; Htet, M.K.; Utomo, B.; Firmansyah, A.; Ferguson, E.L. Local food-based complementary feeding recommendations developed by the linear programming approach to improve the intake of problem nutrients among 12–23-month-old myanmar children. Br. J. Nutr. 2016, 116 (Suppl. 1), S16–S26. [CrossRef] [PubMed]
126. Tadesse, E.; Berhane, Y.; Hjern, A.; Olsson, P.; Ekstrom, E.C. Perceptions of usage and unintended consequences of provision of ready-to-use therapeutic food for management of severe acute child malnutrition. A qualitative study in Southern Ethiopia. Health Policy Plan. 2015, 30, 1334–1341. [CrossRef] [PubMed]
127. PlumpyField. PlumpyField with Nutriset: FAQ. Available online: http://www.plumpyfield.com/faq (accessed on 16 August 2016).
128. Sandige, H.; Ndekha, M.J.; Briend, A.; Ashorn, P.; Manary, M.J. Home-based treatment of malnourished Malawian children with locally produced or imported ready-to-use food. J. Pediatr. Gastroenterol. Nutr. 2004, 39, 141–146. [CrossRef] [PubMed]
129. Bahwere, P.; Banda, T.; Sadler, K.; Nyirenda, G.; Owino, V.; Shaba, B.; Dibari, F.; Collins, S. Effectiveness of milk whey protein-based ready-to-use therapeutic food in treatment of severe acute malnutrition in Malawian under-5 children: A randomised, double-blind, controlled non-inferiority clinical trial. Matern. Child Nutr. 2014, 10, 436–451. [CrossRef] [PubMed]
130. Weber, J.M.; Ryan, K.N.; Tandon, R.; Mathur, M.; Girma, T.; Steiner-Asiedu, M.; Saalia, F.; Zaidi, S.; Soofi, S.; Okos, M. Acceptability of locally produced ready-to-use therapeutic foods in Ethiopia, Ghana, Pakistan and India. Matern. Child Nutr. 2016. [CrossRef] [PubMed]
131. Manary, M. Alternative RUTF Formulas. In Proceedings of the RUTF Pre-Bid Conference, Copenhagen, Denmark, 1–2 July 2015; UNICEF Supply: København, Denmark, 2015.
132. Bahwere, P.; Balaluka, B.; Wells, J.C.; Mbiribindi, C.N.; Sadler, K.; Akomo, P.; Dramaix-Wilmet, M.; Collins, S. Cereals and pulse-based ready-to-use therapeutic food as an alternative to the standard milk- and peanut paste-based formulation for treating severe acute malnutrition: A noninferiority, individually randomized controlled efficacy clinical trial. Am. J. Clin. Nutr. 2016, 103, 1145–1161. [CrossRef] [PubMed]
133. Ackatia-Armah, R.S.; McDonald, C.; Doumbia, S.; Brown, K.H. Effect of selected dietary regimens on recovery from moderate acute malnutrition in young Malian children. FASEB J. 2012, 26 (Suppl. 1), 1031.10.
134. Popkin, B.M.; Latham, M.C. The limitations and dangers of commerciogenic nutritious foods. Am. J. Clin. Nutr. 1973, 26, 1015–1023. [PubMed]
135. Jelliffe, D.B. Commerciogenic Malnutrition? Nutr. Rev. 1972, 30, 199–205. [CrossRef] [PubMed]
136. Lelijveld, N.; Seal, A.; Wells, J.C.; Kirkby, J.; Opondo, C.; Chimwezi, E.; Bunn, J.; Bandsma, R.; Heyderman, R.S.; Nyirenda, M.J.; et al. Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): A cohort study. Lancet Glob. Health 2016, 4, e654–e662. [CrossRef]
137. Talukder, S.H. Vitamin A: The MOON also rises. World Nutr. 2015, 6, 327–332.