-
1
-
-
84940393497
-
A high-sugar and high-fat diet impairs cardiac systolic and diastolic function in mice
-
Carbone S, Mauro AG, Mezzaroma E, Kraskauskas D, Marchetti C, Buzzetti R, et al. A high-sugar and high-fat diet impairs cardiac systolic and diastolic function in mice. Int J Cardiol 2015; 198: 66-69.
-
(2015)
Int J Cardiol
, vol.198
, pp. 66-69
-
-
Carbone, S.1
Mauro, A.G.2
Mezzaroma, E.3
Kraskauskas, D.4
Marchetti, C.5
Buzzetti, R.6
-
3
-
-
64549091508
-
Inflammation as a therapeutic target in heart failure a scientific statement from the translational research committee of the heart failure association of the european society of cardiology
-
Heymans S, Hirsch E, Anker SD, Aukrust P, Balligand J-L, Cohen-Tervaert JW, et al. Inflammation as a therapeutic target in heart failure A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 2009; 11: 119-129.
-
(2009)
Eur J Heart Fail
, vol.11
, pp. 119-129
-
-
Heymans, S.1
Hirsch, E.2
Anker, S.D.3
Aukrust, P.4
Balligand, J.-L.5
Cohen-Tervaert, J.W.6
-
4
-
-
84902280933
-
Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure
-
O'Brien LC, Mezzaroma E, Van Tassell BW, Marchetti C, Carbone S, Abbate A, et al. Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure. Mol Med 2014; 20: 221-229.
-
(2014)
Mol Med
, vol.20
, pp. 221-229
-
-
O'Brien, L.C.1
Mezzaroma, E.2
Van Tassell, B.W.3
Marchetti, C.4
Carbone, S.5
Abbate, A.6
-
5
-
-
84900547879
-
Interleukin-18 mediates interleukin-1-induced cardiac dysfunction
-
Toldo S, Mezzaroma E, O'Brien L, Marchetti C, Seropian IM, Voelkel NF, et al. Interleukin-18 mediates interleukin-1-induced cardiac dysfunction. Am J Physiol Hear Circ Physiol 2014; 306: 1025-1031.
-
(2014)
Am J Physiol Hear Circ Physiol
, vol.306
, pp. 1025-1031
-
-
Toldo, S.1
Mezzaroma, E.2
O'Brien, L.3
Marchetti, C.4
Seropian, I.M.5
Voelkel, N.F.6
-
6
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT-H, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol 2011; 12: 408-415.
-
(2011)
Nat Immunol
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Mt-H, H.6
-
7
-
-
84865108051
-
Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance
-
Reynolds CM, McGillicuddy FC, Harford KA, Finucane OM, Mills KHG, Roche HM. Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance. Mol Nutr Food Res 2012; 56: 1212-1222.
-
(2012)
Mol Nutr Food Res
, vol.56
, pp. 1212-1222
-
-
Reynolds, C.M.1
McGillicuddy, F.C.2
Harford, K.A.3
Finucane, O.M.4
Mills, K.H.G.5
Roche, H.M.6
-
8
-
-
84928013188
-
MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy
-
Li X, Du N, Zhang Q, Li J, Chen X, Liu X, et al. MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy. Cell Death Dis 2014; 5: E1479.
-
(2014)
Cell Death Dis
, vol.5
, pp. E1479
-
-
Li, X.1
Du, N.2
Zhang, Q.3
Li, J.4
Chen, X.5
Liu, X.6
-
9
-
-
84872027781
-
Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR- A gonism correlates with impaired NLRP3 inflammasome activation
-
Collino M, Benetti E, Rogazzo M, Mastrocola R, Yaqoob MM, Aragno M, et al. Reversal of the deleterious effects of chronic dietary HFCS-55 intake by PPAR- A gonism correlates with impaired NLRP3 inflammasome activation. Biochem Pharmacol 2013; 85: 257-264.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 257-264
-
-
Collino, M.1
Benetti, E.2
Rogazzo, M.3
Mastrocola, R.4
Yaqoob, M.M.5
Aragno, M.6
-
10
-
-
78649498271
-
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
-
Stienstra R, Joosten LAB, Koenen T, van Tits B, van Diepen JA, van den Berg SAA, et al. The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab 2010; 12: 593-605.
-
(2010)
Cell Metab
, vol.12
, pp. 593-605
-
-
Stienstra, R.1
Joosten, L.A.B.2
Koenen, T.3
Van Tits, B.4
Van Diepen, J.A.5
Van Den Berg, S.A.A.6
-
11
-
-
84885987718
-
Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages
-
L'homme L, Esser N, Riva L, Scheen A, Paquot N, Piette J, et al. Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages. J Lipid Res 2013; 54: 2998-3008.
-
(2013)
J Lipid Res
, vol.54
, pp. 2998-3008
-
-
L'Homme, L.1
Esser, N.2
Riva, L.3
Scheen, A.4
Paquot, N.5
Piette, J.6
-
12
-
-
84959880427
-
Dietary saturated fatty acid and polyunsaturated fatty acid oppositely affect hepatic NOD-like receptor protein 3 inflammasome through regulating nuclear factor-kappa B activation
-
Sui Y-H, Luo W-J, Xu Q-Y, Hua J. Dietary saturated fatty acid and polyunsaturated fatty acid oppositely affect hepatic NOD-like receptor protein 3 inflammasome through regulating nuclear factor-kappa B activation. World J Gastroenterol 2016; 22: 2533-2544.
-
(2016)
World J Gastroenterol
, vol.22
, pp. 2533-2544
-
-
Sui, Y.-H.1
Luo, W.-J.2
Xu, Q.-Y.3
Hua, J.4
-
13
-
-
33745009509
-
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
-
Netea MG, Joosten LA, Lewis E, Jensen DR, Voshol PJ, Kullberg BJ, et al. Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat Med 2006; 12: 650-656.
-
(2006)
Nat Med
, vol.12
, pp. 650-656
-
-
Netea, M.G.1
Joosten, L.A.2
Lewis, E.3
Jensen, D.R.4
Voshol, P.J.5
Kullberg, B.J.6
-
14
-
-
84920282718
-
Obesity and diastolic heart failure: Is inflammation the link
-
Carbone S, Shah KB, Van Tassell B, JMJ Canada, Evans RK, Regan JA, et al. Obesity and diastolic heart failure: Is inflammation the link Transl Med 2013; 3: E124.
-
(2013)
Transl Med
, vol.3
, pp. E124
-
-
Carbone, S.1
Shah, K.B.2
Van Tassell, B.3
Canada, J.M.J.4
Evans, R.K.5
Regan, J.A.6
-
15
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar B, Youm Y-H, Ravussin A, Galgani JE, Stadler K, Mynatt RL, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 2011; 17: 179-188.
-
(2011)
Nat Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.-H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
-
16
-
-
79959438318
-
Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis
-
Mcgillicuddy FC, Harford KA, Reynolds CM, Oliver E, Claessens M, Mills KHG, et al. Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis. Diabetes 2011; 60: 1688-1698.
-
(2011)
Diabetes
, vol.60
, pp. 1688-1698
-
-
McGillicuddy, F.C.1
Harford, K.A.2
Reynolds, C.M.3
Oliver, E.4
Claessens, M.5
Mills, K.H.G.6
-
17
-
-
0141784866
-
IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions
-
Matsuki T, Horai R, Sudo K, Iwakura Y. IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions. J Exp Med 2003; 198: 877-888.
-
(2003)
J Exp Med
, vol.198
, pp. 877-888
-
-
Matsuki, T.1
Horai, R.2
Sudo, K.3
Iwakura, Y.4
-
18
-
-
85017352381
-
Questions and controversies in innate immune research : What is the physiological role of NLRP3
-
Coll RC, LAJO Neill, Schroder K. Questions and controversies in innate immune research : What is the physiological role of NLRP3 Nat Publ Gr 2016; 1-5.
-
(2016)
Nat Publ Gr
, pp. 1-5
-
-
Coll, R.C.1
Neill, L.2
Schroder, K.3
-
19
-
-
84990221063
-
The HFpEF obesity phenotype: The elephant in the room
-
Kitzman DW, Shah SJ. The HFpEF obesity phenotype: The elephant in the room. J Am Coll Cardiol 2016; 68: 200-203.
-
(2016)
J Am Coll Cardiol
, vol.68
, pp. 200-203
-
-
Kitzman, D.W.1
Shah, S.J.2
-
20
-
-
84999767775
-
Obesity contributes to exercise intolerance in heart failure with preserved ejection fraction
-
Carbone S, Canada JM, Buckley L, Trankle CR, Dixon DL, Buzzetti R, et al. Obesity contributes to exercise intolerance in heart failure with preserved ejection fraction. J Am Coll Cardiol 2016; 68: 2487-2488.
-
(2016)
J Am Coll Cardiol
, vol.68
, pp. 2487-2488
-
-
Carbone, S.1
Canada, J.M.2
Buckley, L.3
Trankle, C.R.4
Dixon, D.L.5
Buzzetti, R.6
-
21
-
-
84877935534
-
Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure
-
Lavie CJ, Alpert MA, Arena R, Mehra MR, Milani RV, Ventura HO. Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure. JACC Heart Fail 2013; 1: 93-102.
-
(2013)
JACC Heart Fail
, vol.1
, pp. 93-102
-
-
Lavie, C.J.1
Alpert, M.A.2
Arena, R.3
Mehra, M.R.4
Milani, R.V.5
Ventura, H.O.6
-
22
-
-
85009806820
-
Obesity and heart failure: Focus on the obesity paradox
-
In press. Available at
-
Carbone S, Lavie CJ, Arena R, et al. Obesity and Heart Failure: Focus on the Obesity Paradox. Mayo Clinic Proceedings 2017. In press. Available at: Http://dx. doi. org/10. 1016/j. mayocp. 2016. 11. 001
-
(2017)
Mayo Clinic Proceedings
-
-
Carbone, S.1
Lavie, C.J.2
Arena, R.3
-
23
-
-
85032138475
-
Interleukin-18 blockade prevents diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction
-
Regan JA, Mauro AG, Carbone S, Marchetti C, Mezzaroma E, Krauskaus D, et al. Interleukin-18 blockade prevents diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction. Circulation 2015; 132: A14648-A14648.
-
(2015)
Circulation
, vol.132
, pp. A14648-A14648
-
-
Regan, J.A.1
Mauro, A.G.2
Carbone, S.3
Marchetti, C.4
Mezzaroma, E.5
Krauskaus, D.6
-
24
-
-
84961917325
-
A study to investigate the efficacy and safety of an anti-interleukin-18 monoclonal antibody in the treatment of type 2 diabetes mellitus
-
McKie EA, Reid JL, Mistry PC, DeWall SL, Abberley L, Ambery PD, et al. A study to investigate the efficacy and safety of an anti-interleukin-18 monoclonal antibody in the treatment of type 2 diabetes mellitus. PLoS One 2016; 11: E0150018.
-
(2016)
PLoS One
, vol.11
, pp. E0150018
-
-
McKie, E.A.1
Reid, J.L.2
Mistry, P.C.3
DeWall, S.L.4
Abberley, L.5
Ambery, P.D.6
-
25
-
-
33746687953
-
Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis
-
Tak PP, Bacchi M, Bertolino M. Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis. Eur J Drug Metab Pharmacokinet 31: 109-116.
-
Eur J Drug Metab Pharmacokinet
, vol.31
, pp. 109-116
-
-
Tak, P.P.1
Bacchi, M.2
Bertolino, M.3
|